Functional Enhancers Shape Extrachromosomal Oncogene Amplifications von Morton, Andrew R., Dogan-Artun, Nergiz, Faber, Zachary J., MacLeod, Graham, Bartels, Cynthia F., Piazza, Megan S., Allan, Kevin C., Mack, Stephen C., Wang, Xiuxing, Gimple, Ryan C., Wu, Qiulian, Rubin, Brian P., Shetty, Shashirekha, Angers, Stephane, Dirks, Peter B., Sallari, Richard C., Lupien, Mathieu, Rich, Jeremy N., Scacheri, Peter C.

Volltext

Brain Tumor Stem Cells: Bringing Order to the Chaos of Brain Cancer von Dirks, Peter B

Volltext

GLUT1 inhibition blocks growth of RB1-positive triple negative breast cancer von Wu, Qin, ba-alawi, Wail, Deblois, Genevieve, Cruickshank, Jennifer, Duan, Shili, Lima-Fernandes, Evelyne, Haight, Jillian, Tonekaboni, Seyed Ali Madani, Fortier, Anne-Marie, Kuasne, Hellen, McKee, Trevor D., Mahmoud, Hassan, Kushida, Michelle, Cameron, Sarina, Dogan-Artun, Nergiz, Chen, WenJun, Nie, Yan, Zhang, Lan Xin, Vellanki, Ravi N., Zhou, Stanley, Prinos, Panagiotis, Wouters, Bradly G., Dirks, Peter B., Done, Susan J., Park, Morag, Cescon, David W., Haibe-Kains, Benjamin, Lupien, Mathieu, Arrowsmith, Cheryl H.

Volltext

Single cell-derived clonal analysis of human glioblastoma links functional and genomic heterogeneity von Meyer, Mona, Reimand, Jüri, Lan, Xiaoyang, Head, Renee, Zhu, Xueming, Kushida, Michelle, Bayani, Jane, Pressey, Jessica C., Lionel, Anath C., Clarke, Ian D., Cusimano, Michael, Squire, Jeremy A., Scherer, Stephen W., Bernstein, Mark, Woodin, Melanie A., Bader, Gary D., Dirks, Peter B.

Volltext

Fate mapping of human glioblastoma reveals an invariant stem cell hierarchy von Lan, Xiaoyang, Jörg, David J., Cavalli, Florence M. G., Richards, Laura M., Nguyen, Long V., Vanner, Robert J., Guilhamon, Paul, Lee, Lilian, Kushida, Michelle M., Pellacani, Davide, Park, Nicole I., Coutinho, Fiona J., Whetstone, Heather, Selvadurai, Hayden J., Che, Clare, Luu, Betty, Carles, Annaick, Moksa, Michelle, Rastegar, Naghmeh, Head, Renee, Dolma, Sonam, Prinos, Panagiotis, Cusimano, Michael D., Das, Sunit, Bernstein, Mark, Arrowsmith, Cheryl H., Mungall, Andrew J., Moore, Richard A., Ma, Yussanne, Gallo, Marco, Lupien, Mathieu, Pugh, Trevor J., Taylor, Michael D., Hirst, Martin, Eaves, Connie J., Simons, Benjamin D., Dirks, Peter B.

Volltext

The current consensus on the clinical management of intracranial ependymoma and its distinct molecular variants von Pajtler, Kristian W., Mack, Stephen C., Ramaswamy, Vijay, Smith, Christian A., Witt, Hendrik, Smith, Amy, Hansford, Jordan R., von Hoff, Katja, Wright, Karen D., Hwang, Eugene, Frappaz, Didier, Kanemura, Yonehiro, Massimino, Maura, Faure-Conter, Cécile, Modena, Piergiorgio, Tabori, Uri, Warren, Katherine E., Holland, Eric C., Ichimura, Koichi, Giangaspero, Felice, Castel, David, von Deimling, Andreas, Kool, Marcel, Dirks, Peter B., Grundy, Richard G., Foreman, Nicholas K., Gajjar, Amar, Korshunov, Andrey, Finlay, Jonathan, Gilbertson, Richard J., Ellison, David W., Aldape, Kenneth D., Merchant, Thomas E., Bouffet, Eric, Pfister, Stefan M., Taylor, Michael D.

Volltext

Genome-Wide CRISPR-Cas9 Screens Expose Genetic Vulnerabilities and Mechanisms of Temozolomide Sensitivity in Glioblastoma Stem Cells von MacLeod, Graham, Bozek, Danielle A., Rajakulendran, Nishani, Monteiro, Vernon, Ahmadi, Moloud, Steinhart, Zachary, Kushida, Michelle M., Yu, Helen, Coutinho, Fiona J., Cavalli, Florence M.G., Restall, Ian, Hao, Xiaoguang, Hart, Traver, Luchman, H. Artee, Weiss, Samuel, Dirks, Peter B., Angers, Stephane

Volltext

Inhibition of Dopamine Receptor D4 Impedes Autophagic Flux, Proliferation, and Survival of Glioblastoma Stem Cells von Dolma, Sonam, Selvadurai, Hayden J., Lan, Xiaoyang, Lee, Lilian, Kushida, Michelle, Voisin, Veronique, Whetstone, Heather, So, Milly, Aviv, Tzvi, Park, Nicole, Zhu, Xueming, Xu, ChangJiang, Head, Renee, Rowland, Katherine J., Bernstein, Mark, Clarke, Ian D., Bader, Gary, Harrington, Lea, Brumell, John H., Tyers, Mike, Dirks, Peter B.

Volltext

Pervasive H3K27 Acetylation Leads to ERV Expression and a Therapeutic Vulnerability in H3K27M Gliomas von Krug, Brian, De Jay, Nicolas, Harutyunyan, Ashot S., Deshmukh, Shriya, Marchione, Dylan M., Guilhamon, Paul, Bertrand, Kelsey C., Mikael, Leonie G., McConechy, Melissa K., Chen, Carol C.L., Khazaei, Sima, Koncar, Robert F., Agnihotri, Sameer, Faury, Damien, Ellezam, Benjamin, Weil, Alexander G., Ursini-Siegel, Josie, De Carvalho, Daniel D., Dirks, Peter B., Lewis, Peter W., Salomoni, Paolo, Lupien, Mathieu, Arrowsmith, Cheryl, Lasko, Paul F., Garcia, Benjamin A., Kleinman, Claudia L., Jabado, Nada, Mack, Stephen C.

Volltext

BRAF mutation and CDKN2A deletion define a clinically distinct subgroup of childhood secondary high-grade glioma von Mistry, Matthew, Zhukova, Nataliya, Merico, Daniele, Rakopoulos, Patricia, Krishnatry, Rahul, Shago, Mary, Stavropoulos, James, Alon, Noa, Pole, Jason D, Ray, Peter N, Navickiene, Vilma, Mangerel, Joshua, Remke, Marc, Buczkowicz, Pawel, Ramaswamy, Vijay, Guerreiro Stucklin, Ana, Li, Martin, Young, Edwin J, Zhang, Cindy, Castelo-Branco, Pedro, Bakry, Doua, Laughlin, Suzanne, Shlien, Adam, Chan, Jennifer, Ligon, Keith L, Rutka, James T, Dirks, Peter B, Taylor, Michael D, Greenberg, Mark, Malkin, David, Huang, Annie, Bouffet, Eric, Hawkins, Cynthia E, Tabori, Uri

Volltext

DNA hypermethylation within TERT promoter upregulates TERT expression in cancer von Lee, Donghyun D, Leão, Ricardo, Komosa, Martin, Gallo, Marco, Zhang, Cindy H, Lipman, Tatiana, Remke, Marc, Heidari, Abolfazl, Nunes, Nuno Miguel, Apolónio, Joana D, Price, Aryeh J, De Mello, Ramon Andrade, Dias, João S, Huntsman, David, Hermanns, Thomas, Wild, Peter J, Vanner, Robert, Zadeh, Gelareh, Karamchandani, Jason, Das, Sunit, Taylor, Michael D, Hawkins, Cynthia E, Wasserman, Jonathan D, Figueiredo, Arnaldo, Hamilton, Robert J, Minden, Mark D, Wani, Khalida, Diplas, Bill, Yan, Hai, Aldape, Kenneth, Akbari, Mohammad R, Danesh, Arnavaz, Pugh, Trevor J, Dirks, Peter B, Castelo-Branco, Pedro, Tabori, Uri

Volltext

Brain tumor stem cells: The cancer stem cell hypothesis writ large von Dirks, Peter B.

Volltext

Foramen magnum stenosis in a 5-month-old boy with achondroplasia von Malhotra, Armaan K, Parker, Whitney, Dirks, Peter B

Volltext

The white matter is a pro-differentiative niche for glioblastoma von Brooks, Lucy J., Clements, Melanie P., Burden, Jemima J., Kocher, Daniela, Richards, Luca, Devesa, Sara Castro, Zakka, Leila, Woodberry, Megan, Ellis, Michael, Jaunmuktane, Zane, Brandner, Sebastian, Morrison, Gillian, Pollard, Steven M., Dirks, Peter B., Marguerat, Samuel, Parrinello, Simona

Volltext

Survival and functional outcomes of molecularly defined childhood posterior fossa ependymoma: Cure at a cost von Zapotocky, Michal, Beera, Kiran, Adamski, Jenny, Laperierre, Normand, Guger, Sharon, Janzen, Laura, Lassaletta, Alvaro, Figueiredo Nobre, Liana, Bartels, Ute, Tabori, Uri, Hawkins, Cynthia, Urbach, Stacey, Tsang, Derek S., Dirks, Peter B., Taylor, Michael D., Bouffet, Eric, Mabbott, Donald J., Ramaswamy, Vijay

Volltext

ASCL1 Reorganizes Chromatin to Direct Neuronal Fate and Suppress Tumorigenicity of Glioblastoma Stem Cells von Park, Nicole I., Guilhamon, Paul, Desai, Kinjal, McAdam, Rochelle F., Langille, Ellen, O’Connor, Madlen, Lan, Xiaoyang, Whetstone, Heather, Coutinho, Fiona J., Vanner, Robert J., Ling, Erick, Prinos, Panagiotis, Lee, Lilian, Selvadurai, Hayden, Atwal, Gurnit, Kushida, Michelle, Clarke, Ian D., Voisin, Veronique, Cusimano, Michael D., Bernstein, Mark, Das, Sunit, Bader, Gary, Arrowsmith, Cheryl H., Angers, Stephane, Huang, Xi, Lupien, Mathieu, Dirks, Peter B.

Volltext

Quiescent Sox2+ Cells Drive Hierarchical Growth and Relapse in Sonic Hedgehog Subgroup Medulloblastoma von Vanner, Robert J., Remke, Marc, Gallo, Marco, Selvadurai, Hayden J., Coutinho, Fiona, Lee, Lilian, Kushida, Michelle, Head, Renee, Morrissy, Sorana, Zhu, Xueming, Aviv, Tzvi, Voisin, Veronique, Clarke, Ian D., Li, Yisu, Mungall, Andrew J., Moore, Richard A., Ma, Yussanne, Jones, Steven J.M., Marra, Marco A., Malkin, David, Northcott, Paul A., Kool, Marcel, Pfister, Stefan M., Bader, Gary, Hochedlinger, Konrad, Korshunov, Andrey, Taylor, Michael D., Dirks, Peter B.

Volltext

Cancer stem cells--perspectives on current status and future directions: AACR Workshop on cancer stem cells von Clarke, Michael F, Dick, John E, Dirks, Peter B, Eaves, Connie J, Jamieson, Catriona H M, Jones, D Leanne, Visvader, Jane, Weissman, Irving L, Wahl, Geoffrey M

Volltext

Single-cell chromatin profiling of the primitive gut tube reveals regulatory dynamics underlying lineage fate decisions von Smith, Ryan J., Zhang, Hongpan, Hu, Shengen Shawn, Yung, Theodora, Francis, Roshane, Lee, Lilian, Onaitis, Mark W., Dirks, Peter B., Zang, Chongzhi, Kim, Tae-Hee

Volltext

Cancer stem cells in gliomas: Identifying and understanding the apex cell in cancer's hierarchy von Venere, Monica, Fine, Howard A., Dirks, Peter B., Rich, Jeremy N.

Volltext