Identification and evaluation of small-molecule inhibitors against the dNTPase SAMHD1 via a comprehensive screening funnel von Zhang, Si Min, Paulin, Cynthia B.J., Shu, Huazhang, Yagüe-Capilla, Miriam, Michel, Maurice, Marttila, Petra, Ortis, Florian, Bwanika, Henri Colyn, Dirks, Christopher, Venkatram, Rajagopal Papagudi, Wiita, Elisée, Jemth, Ann-Sofie, Almlöf, Ingrid, Loseva, Olga, Hormann, Femke M., Koolmeister, Tobias, Linde, Erika, Lee, Sun, Llona-Minguez, Sabin, Haraldsson, Martin, Axelsson, Hanna, Strömberg, Kia, Homan, Evert J., Scobie, Martin, Lundbäck, Thomas, Helleday, Thomas, Rudd, Sean G.

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The N-terminal SAM domain of the dNTPase SAMHD1 is not required for inhibition by small molecule TH6342 von Dirks, C, Bwanika, HC, Jemth, A-S, Zhang, SM, Rudd, SG

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A large-scale sORF screen identifies putative microproteins involved in cancer cell fitness von Schlesinger, Dörte, Dirks, Christopher, Navarro, Carmen, Lafranchi, Lorenzo, Spinner, Anna, Raja, Glancis Luzeena, Mun-Sum Tong, Gregory, Eirich, Jürgen, Martinez, Thomas Farid, Elsässer, Simon Johannes

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Exploiting blood-based biomarkers to align preclinical models with human traumatic brain injury von Lisi, Ilaria, Moro, Federico, Mazzone, Edoardo, Marklund, Niklas, Pischiutta, Francesca, Kobeissy, Firas, Mao, Xiang, Corrigan, Frances, Helmy, Adel, Nasrallah, Fatima, Di Pietro, Valentina, Ngwenya, Laura B, Portela, Luis V, Semple, Bridgette D, Schneider, Andrea L C, Diaz Arrastia, Ramon, Menon, David K, Smith, Douglas H, Wellington, Cheryl, Loane, David J, Wang, Kevin, Zanier, Elisa R

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Identification and evaluation of small-molecule inhibitors against the dNTPase SAMHD1 via a comprehensive screening funnel von Zhang, Si Min, Paulin, Cynthia B.J, Shu, Huazhang, Yagüe-Capilla, Miriam, Michel, Maurice, Marttila, Petra, Ortis, Florian, Bwanika, Henri Colyn Harry, Dirks, Christopher, Venkatram, Rajagopal Papagudi, Wiita, Elisée, Jemth, Ann-Sofie, Almlöf, Ingrid, Loseva, Olga, Hormann, Femke M, Koolmeister, Tobias, Linde, Erika, Lee, Sun, Llona-Minguez, Sabin, Haraldsson, Martin, Axelsson, Hanna, Strömberg, Kia, Homan, Evert J, Scobie, Martin, Lundbäck, Thomas, Helleday, Thomas, Rudd, Sean G

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Vericiguat in Patients with Heart Failure and Reduced Ejection Fraction von Armstrong, Paul W, Pieske, Burkert, Anstrom, Kevin J, Ezekowitz, Justin, Hernandez, Adrian F, Butler, Javed, Lam, Carolyn S.P, Ponikowski, Piotr, Voors, Adriaan A, Jia, Gang, McNulty, Steven E, Patel, Mahesh J, Roessig, Lothar, Koglin, Joerg, O’Connor, Christopher M

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Diabetic Retinopathy in Type 2 Diabetes Mellitus Patients Attending the Diabetic Clinic of the University of Gondar Hospital, Northwest Ethiopia von Tsegaw, Asamere, Alemu, Shitaye, Dessie, Abere, Patterson, Christopher C., Parry, Eldryd H. O., Phillips, David I. W., Trimble, Elisabeth R.

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Sensitivity and Specificity of a Point-of-Care Matrix Metalloproteinase 9 Immunoassay for Diagnosing Inflammation Related to Dry Eye von Sambursky, Robert, Davitt, William F, Latkany, Robert, Tauber, Shachar, Starr, Christopher, Friedberg, Murray, Dirks, Monte S, McDonald, Marguerite

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Sotagliflozin in Patients with Diabetes and Recent Worsening Heart Failure von Bhatt, Deepak L, Szarek, Michael, Steg, P. Gabriel, Cannon, Christopher P, Leiter, Lawrence A, McGuire, Darren K, Lewis, Julia B, Riddle, Matthew C, Voors, Adriaan A, Metra, Marco, Lund, Lars H, Komajda, Michel, Testani, Jeffrey M, Wilcox, Christopher S, Ponikowski, Piotr, Lopes, Renato D, Verma, Subodh, Lapuerta, Pablo, Pitt, Bertram

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Single-cell chromatin accessibility profiling of glioblastoma identifies an invasive cancer stem cell population associated with lower survival von Guilhamon, Paul, Chesnelong, Charles, Kushida, Michelle M, Nikolic, Ana, Singhal, Divya, MacLeod, Graham, Madani Tonekaboni, Seyed Ali, Cavalli, Florence Mg, Arlidge, Christopher, Rajakulendran, Nishani, Rastegar, Naghmeh, Hao, Xiaoguang, Hassam, Rozina, Smith, Laura J, Whetstone, Heather, Coutinho, Fiona J, Nadorp, Bettina, Ellestad, Katrina I, Luchman, H Artee, Chan, Jennifer Ai-Wen, Shoichet, Molly S, Taylor, Michael D, Haibe-Kains, Benjamin, Weiss, Samuel, Angers, Stephane, Gallo, Marco, Dirks, Peter B, Lupien, Mathieu

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Relatlimab and Nivolumab versus Nivolumab in Untreated Advanced Melanoma von Tawbi, Hussein A, Schadendorf, Dirk, Lipson, Evan J, Ascierto, Paolo A, Matamala, Luis, Castillo Gutiérrez, Erika, Rutkowski, Piotr, Gogas, Helen J, Lao, Christopher D, De Menezes, Juliana Janoski, Dalle, Stéphane, Arance, Ana, Grob, Jean-Jacques, Srivastava, Shivani, Abaskharoun, Mena, Hamilton, Melissa, Keidel, Sarah, Simonsen, Katy L, Sobiesk, Anne Marie, Li, Bin, Hodi, F. Stephen, Long, Georgina V

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macroH2A2 antagonizes epigenetic programs of stemness in glioblastoma von Nikolic, Ana, Maule, Francesca, Bobyn, Anna, Ellestad, Katrina, Paik, Seungil, Marhon, Sajid A., Mehdipour, Parinaz, Lun, Xueqing, Chen, Huey-Miin, Mallard, Claire, Hay, Alexander J., Johnston, Michael J., Gafuik, Christopher J., Zemp, Franz J., Shen, Yaoqing, Ninkovic, Nicoletta, Osz, Katalin, Labit, Elodie, Berger, N. Daniel, Brownsey, Duncan K., Kelly, John J., Biernaskie, Jeff, Dirks, Peter B., Derksen, Darren J., Jones, Steven J. M., Senger, Donna L., Chan, Jennifer A., Mahoney, Douglas J., De Carvalho, Daniel D., Gallo, Marco

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Short-Term Outcomes following “Switching” to Monthly Ranibizumab in Neovascular Age-Related Macular Degeneration Showing Insufficient Response to Bimonthly Aflibercept von Lee, Jong Suk, Kang, Hyun Goo, Lee, Christopher Seungkyu, Woo, Se Joon

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Vegan and Omnivorous High Protein Diets Support Comparable Daily Myofibrillar Protein Synthesis Rates and Skeletal Muscle Hypertrophy in Young Adults von Monteyne, Alistair J., Coelho, Mariana O.C., Murton, Andrew J., Abdelrahman, Doaa R., Blackwell, Jamie R., Koscien, Christopher P., Knapp, Karen M., Fulford, Jonathan, Finnigan, Tim J.A., Dirks, Marlou L., Stephens, Francis B., Wall, Benjamin T.

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Integrated Molecular and Clinical Analysis of 1,000 Pediatric Low-Grade Gliomas von Ryall, Scott, Zapotocky, Michal, Fukuoka, Kohei, Nobre, Liana, Guerreiro Stucklin, Ana, Bennett, Julie, Siddaway, Robert, Li, Christopher, Pajovic, Sanja, Arnoldo, Anthony, Kowalski, Paul E., Johnson, Monique, Sheth, Javal, Lassaletta, Alvaro, Tatevossian, Ruth G., Orisme, Wilda, Qaddoumi, Ibrahim, Surrey, Lea F., Li, Marilyn M., Waanders, Angela J., Gilheeney, Stephen, Rosenblum, Marc, Bale, Tejus, Tsang, Derek S., Laperriere, Normand, Kulkarni, Abhaya, Ibrahim, George M., Drake, James, Dirks, Peter, Taylor, Michael D., Rutka, James T., Laughlin, Suzanne, Shroff, Manohar, Shago, Mary, Hazrati, Lili-Naz, D'Arcy, Colleen, Ramaswamy, Vijay, Bartels, Ute, Huang, Annie, Bouffet, Eric, Karajannis, Matthias A., Santi, Mariarita, Ellison, David W., Tabori, Uri, Hawkins, Cynthia

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Age-Adjusted D-Dimer in the Prediction of Pulmonary Embolism: Does a Normal Age-Adjusted D-Dimer Rule Out PE? von Ortiz, Jacob, Saeed, Rabia, Little, Christopher, Schaefer, Saul

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2019 ESC Guidelines for the diagnosis and management of chronic coronary syndromes von Knuuti, Juhani, Wijns, William, Saraste, Antti, Capodanno, Davide, Barbato, Emanuele, Funck-Brentano, Christian, Prescott, Eva, Storey, Robert F, Deaton, Christi, Cuisset, Thomas, Agewall, Stefan, Dickstein, Kenneth, Edvardsen, Thor, Escaned, Javier, Gersh, Bernard J, Svitil, Pavel, Gilard, Martine, Hasdai, David, Hatala, Robert, Mahfoud, Felix, Masip, Josep, Muneretto, Claudio, Valgimigli, Marco, Achenbach, Stephan, Bax, Jeroen J

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Authentication of M14 melanoma cell line proves misidentification of MDA‐MB‐435 breast cancer cell line von Korch, Christopher, Hall, Erin M., Dirks, Wilhelm G., Ewing, Margaret, Faries, Mark, Varella‐Garcia, Marileila, Robinson, Steven, Storts, Douglas, Turner, Jacqueline A., Wang, Ying, Burnett, Edward C., Healy, Lyn, Kniss, Douglas, Neve, Richard M., Nims, Raymond W., Reid, Yvonne A., Robinson, William A., Capes‐Davis, Amanda

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Air Pollution Exposure in Relation to the Commute to School: A Bradford UK Case Study von Dirks, Kim N, Wang, Judith Y T, Khan, Amirul, Rushton, Christopher

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Combined hereditary and somatic mutations of replication error repair genes result in rapid onset of ultra-hypermutated cancers von Shlien, Adam, Campbell, Brittany B, de Borja, Richard, Alexandrov, Ludmil B, Merico, Daniele, Wedge, David, Van Loo, Peter, Tarpey, Patrick S, Coupland, Paul, Behjati, Sam, Pollett, Aaron, Lipman, Tatiana, Heidari, Abolfazl, Deshmukh, Shriya, Avitzur, Na'ama, Meier, Bettina, Gerstung, Moritz, Hong, Ye, Merino, Diana M, Ramakrishna, Manasa, Remke, Marc, Arnold, Roland, Panigrahi, Gagan B, Thakkar, Neha P, Hodel, Karl P, Henninger, Erin E, Göksenin, A Yasemin, Bakry, Doua, Charames, George S, Druker, Harriet, Lerner-Ellis, Jordan, Mistry, Matthew, Dvir, Rina, Grant, Ronald, Elhasid, Ronit, Farah, Roula, Taylor, Glenn P, Nathan, Paul C, Alexander, Sarah, Ben-Shachar, Shay, Ling, Simon C, Gallinger, Steven, Constantini, Shlomi, Dirks, Peter, Huang, Annie, Scherer, Stephen W, Grundy, Richard G, Durno, Carol, Aronson, Melyssa, Gartner, Anton, Meyn, M Stephen, Taylor, Michael D, Pursell, Zachary F, Pearson, Christopher E, Malkin, David, Futreal, P Andrew, Stratton, Michael R, Bouffet, Eric, Hawkins, Cynthia, Campbell, Peter J, Tabori, Uri

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