Genotoxic aldehydes in the hematopoietic system von Wang, Meng, Dingler, Felix A., Patel, K.J.

Volltext

Single-Cell RNA Sequencing Reveals T Helper Cells Synthesizing Steroids De Novo to Contribute to Immune Homeostasis von Mahata, Bidesh, Zhang, Xiuwei, Kolodziejczyk, Aleksandra A., Proserpio, Valentina, Haim-Vilmovsky, Liora, Taylor, Angela E., Hebenstreit, Daniel, Dingler, Felix A., Moignard, Victoria, Göttgens, Berthold, Arlt, Wiebke, McKenzie, Andrew N.J., Teichmann, Sarah A.

Volltext

Germline ablation of SMUG1 DNA glycosylase causes loss of 5-hydroxymethyluracil- and UNG-backup uracil-excision activities and increases cancer predisposition of Ung-/-Msh2-/- mice von Kemmerich, Kristin, Dingler, Felix A, Rada, Cristina, Neuberger, Michael S

Volltext

Nanomagnet logic: progress toward system-level integration von Niemier, M T, Bernstein, G H, Csaba, G, Dingler, A, Hu, X S, Kurtz, S, Liu, S, Nahas, J, Porod, W, Siddiq, M, Varga, E

Volltext

Mammals divert endogenous genotoxic formaldehyde into one-carbon metabolism von Burgos-Barragan, Guillermo, Wit, Niek, Meiser, Johannes, Dingler, Felix A., Pietzke, Matthias, Mulderrig, Lee, Pontel, Lucas B., Rosado, Ivan V., Brewer, Thomas F., Cordell, Rebecca L., Monks, Paul S., Chang, Christopher J., Vazquez, Alexei, Patel, Ketan J.

Volltext

Aldehyde-driven transcriptional stress triggers an anorexic DNA damage response von Mulderrig, Lee, Garaycoechea, Juan I., Tuong, Zewen K., Millington, Christopher L., Dingler, Felix A., Ferdinand, John R., Gaul, Liam, Tadross, John A., Arends, Mark J., O’Rahilly, Stephen, Crossan, Gerry P., Clatworthy, Menna R., Patel, Ketan J.

Volltext

Production of solid lipid nanoparticles (SLN): scaling up feasibilities von Dingler, A., Gohla, S.

Volltext

Uracil excision by endogenous SMUG1 glycosylase promotes efficient Ig class switching and impacts on A:T substitutions during somatic mutation von Dingler, Felix A., Kemmerich, Kristin, Neuberger, Michael S., Rada, Cristina

Volltext

Aminobenzothiazole derivatives stabilize the thermolabile p53 cancer mutant Y220C and show anticancer activity in p53-Y220C cell lines von Baud, Matthias G.J., Bauer, Matthias R., Verduci, Lorena, Dingler, Felix A., Patel, Ketan J., Horil Roy, Deeptee, Joerger, Andreas C., Fersht, Alan R.

Volltext

Formaldehyde regulates S -adenosylmethionine biosynthesis and one-carbon metabolism von Pham, Vanha N, Bruemmer, Kevin J, Toh, Joel D W, Ge, Eva J, Tenney, Logan, Ward, Carl C, Dingler, Felix A, Millington, Christopher L, Garcia-Prieto, Carlos A, Pulos-Holmes, Mia C, Ingolia, Nicholas T, Pontel, Lucas B, Esteller, Manel, Patel, Ketan J, Nomura, Daniel K, Chang, Christopher J

Volltext

Two Aldehyde Clearance Systems Are Essential to Prevent Lethal Formaldehyde Accumulation in Mice and Humans von Dingler, Felix A., Wang, Meng, Mu, Anfeng, Millington, Christopher L., Oberbeck, Nina, Watcham, Sam, Pontel, Lucas B., Kamimae-Lanning, Ashley N., Langevin, Frederic, Nadler, Camille, Cordell, Rebecca L., Monks, Paul S., Yu, Rui, Wilson, Nicola K., Hira, Asuka, Yoshida, Kenichi, Mori, Minako, Okamoto, Yusuke, Okuno, Yusuke, Muramatsu, Hideki, Shiraishi, Yuichi, Kobayashi, Masayuki, Moriguchi, Toshinori, Osumi, Tomoo, Kato, Motohiro, Miyano, Satoru, Ito, Etsuro, Kojima, Seiji, Yabe, Hiromasa, Yabe, Miharu, Matsuo, Keitaro, Ogawa, Seishi, Göttgens, Berthold, Hodskinson, Michael R.G., Takata, Minoru, Patel, Ketan J.

Volltext

Genotoxic aldehyde stress prematurely ages hematopoietic stem cells in a p53-driven manner von Wang, Meng, Brandt, Laura T.L., Wang, Xiaonan, Russell, Holly, Mitchell, Emily, Kamimae-Lanning, Ashley N., Brown, Jill M., Dingler, Felix A., Garaycoechea, Juan I., Isobe, Tomoya, Kinston, Sarah J., Gu, Muxin, Vassiliou, George S., Wilson, Nicola K., Göttgens, Berthold, Patel, Ketan J.

Volltext

A structure-guided molecular chaperone approach for restoring the transcriptional activity of the p53 cancer mutant Y220C von Bauer, Matthias R, Jones, Rhiannon N, Tareque, Raysa K, Springett, Bradley, Dingler, Felix A, Verduci, Lorena, Patel, Ketan J, Fersht, Alan R, Joerger, Andreas C, Spencer, John

Volltext

Of sizzling steaks and DNA repair von Dingler, Felix A., Patel, Ketan J.

Volltext

Aldehyde-mediated inhibition of asparagine biosynthesis has implications for diabetes and alcoholism von John, Tobias, Saffoon, Nadia, Walsby-Tickle, John, Hester, Svenja S, Dingler, Felix A, Millington, Christopher L, McCullagh, James S. O, Patel, Ketan J, Hopkinson, Richard J, Schofield, Christopher J

Volltext

Erratum: Mammals divert endogenous genotoxic formaldehyde into one-carbon metabolism von Burgos-Barragan, Guillermo, Wit, Niek, Meiser, Johannes, Dingler, Felix A., Pietzke, Matthias, Mulderrig, Lee, Pontel, Lucas B., Rosado, Ivan V., Brewer, Thomas F., Cordell, Rebecca L., Monks, Paul S., Chang, Christopher J., Vazquez, Alexei, Patel, Ketan J.

Volltext

Gallbladder polyps - a follow-up study after 11 years von Heitz, Linda, Kratzer, Wolfgang, Gräter, Tilmann, Schmidberger, Julian

Volltext

Subclinical and clinical hypothyroidism and non-alcoholic fatty liver disease: a cross-sectional study of a random population sample aged 18 to 65 years von Ludwig, Ulla, Holzner, Daniela, Denzer, Christian, Greinert, Artur, Haenle, Mark Martin, Oeztuerk, Suemeyra, Koenig, Wolfgang, Boehm, Bernhard Otto, Mason, Richard Andrew, Kratzer, Wolfgang, Graeter, Tilmann

Volltext

Scaling up feasibility of the production of solid lipid nanoparticles (SLN) von GOHLA, S. H, DINGLER, A

Volltext

Shape Engineering for Controlled Switching With Nanomagnet Logic von Niemier, M. T., Varga, E., Bernstein, G. H., Porod, W., Alam, M. T., Dingler, A., Orlov, A., Hu, X. S.

Volltext