Clinical Trial Substantiates the Predictive Value of O-6-Methylguanine-DNA Methyltransferase Promoter Methylation in Glioblastoma Patients Treated with Temozolomide von HEGI, Monika E, DISERENS, Annie-Claire, GODARD, Sophie, DIETRICH, Pierre-Yves, REGLI, Luca, OSTERMANN, Sandrine, OTTEN, Philippe, VAN MELLE, Guy, DE TRIBOLET, Nicolas, STUPP, Roger

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Homing Phenotypes of Tumor-Specific CD8 T Cells Are Predetermined at the Tumor Site by Crosspresenting APCs von Calzascia, Thomas, Masson, Frédérick, Di Berardino-Besson, Wilma, Contassot, Emmanuel, Wilmotte, Rick, Aurrand-Lions, Michel, Rüegg, Curzio, Dietrich, Pierre-Yves, Walker, Paul R.

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Clinical activity of rituximab in extranodal marginal zone B-cell lymphoma of MALT type von Conconi, Annarita, Martinelli, Giovanni, Thiéblemont, Catherine, Ferreri, AndresJ.M, Devizzi, Liliana, Peccatori, Fedro, Ponzoni, Maurilio, Pedrinis, Ennio, Dell’Oro, Stefania, Pruneri, Giancarlo, Filipazzi, Virginio, Dietrich, Pierre-Yves, Gianni, Alessandro M., Coiffier, Bertrand, Cavalli, Franco, Zucca, Emanuele

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Classification of human astrocytic gliomas on the basis of gene expression: a correlated group of genes with angiogenic activity emerges as a strong predictor of subtypes von Godard, Sophie, Getz, Gad, Delorenzi, Mauro, Farmer, Pierre, Kobayashi, Hiroyuki, Desbaillets, Isabelle, Nozaki, Michimasa, Diserens, Annie-Claire, Hamou, Marie-France, Dietrich, Pierre-Yves, Regli, Luca, Janzer, Robert C, Bucher, Philipp, Stupp, Roger, de Tribolet, Nicolas, Domany, Eytan, Hegi, Monika E

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Multicenter phase II trial of temozolomide in patients with glioblastoma multiforme at first relapse von Brada, M., Hoang-Xuan, K., Rampling, R., Dietrich, P-Y., Dirix, L. Y., Macdonald, D., Heimans, J. J., Zonnenberg, B. A., Bravo-Marques, J. M., Henriksson, R., Stupp, R., Yue, N., Bruner, J., Dugan, M., Rao, S., Zaknoen, S.

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Expression and localization of VEGF-C and VEGFR-3 in glioblastomas and haemangioblastomas von Jenny, B, Harrison, JA, Baetens, D, Tille, J-C, Burkhardt, K, Mottaz, H, Kiss, JZ, Dietrich, P-Y, De Tribolet, N, Pizzolato, GP, Pepper, MS

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Antigenicity and immunogenicity of Melan-A/MART-1 derived peptides as targets for tumor reactive CTL in human melanoma von Romero, Pedro, Valmori, Danila, Pittet, Mikael J., Zippelius, Alfred, Rimoldi, Donata, Lévy, Frederic, Dutoit, Valérie, Ayyoub, Maha, Rubio-Godoy, Verena, Michielin, Olivier, Guillaume, Philippe, Batard, Pascal, Luescher, Immanuel F., Lejeune, Ferdy, Liénard, Danielle, Rufer, Nathalie, Dietrich, Pierre-Yves, Speiser, Daniel E., Cerottini, Jean-Charles

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Arachidonyl ethanolamide induces apoptosis of uterine cervix cancer cells via aberrantly expressed vanilloid receptor-1 von Contassot, Emmanuel, Tenan, Mirna, Schnüriger, Valérie, Pelte, Marie-Françoise, Dietrich, Pierre-Yves

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TWEAK stimulation of astrocytes and the proinflammatory consequences von Saas, Philippe, Boucraut, José, Walker, Paul R., Quiquerez, Anne-Lise, Billot, Maryse, Desplat-Jego, Sophie, Chicheportiche, Yves, Dietrich, Pierre-Yves

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Heterogeneous T-cell response to MAGE-A10(254-262): high avidity-specific cytolytic T lymphocytes show superior antitumor activity von Dutoit, V, Rubio-Godoy, V, Dietrich, P Y, Quiqueres, A L, Schnuriger, V, Rimoldi, D, Liénard, D, Speiser, D, Guillaume, P, Batard, P, Cerottini, J C, Romero, P, Valmori, D

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Tumor expression of Fas ligand (CD95L) and the consequences von Walker, Paul R, Saas, Philippe, Dietrich, Pierre-Yves

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CD95 (Fas/Apo-1) as a Receptor Governing Astrocyte Apoptotic or Inflammatory Responses: A Key Role in Brain Inflammation? von Saas, Philippe, Boucraut, Jose, Quiquerez, Anne-Lise, Schnuriger, Valerie, Perrin, Gaelle, Desplat-Jego, Sophie, Bernard, Dominique, Walker, Paul R, Dietrich, Pierre-Yves

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Soluble CD86 Is a Costimulatory Molecule for Human T Lymphocytes von Jeannin, Pascale, Magistrelli, Giovanni, Aubry, Jean-Pierre, Caron, Gersende, Gauchat, Jean-François, Renno, Toufic, Herbault, Nathalie, Goetsch, Liliane, Blaecke, Aline, Dietrich, Pierre-Yves, Bonnefoy, Jean-Yves, Delneste, Yves

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High frequency of functionally active melan-A-specific T cells in a patient with progressive immunoproteasome-deficient melanoma von MEIDENBAUER, Norbert, ZIPPELIUS, Alfred, DIETRICH, Pierre Y, ANDREESEN, Reinhard, ROMERO, Pedro, MACKENSEN, Andreas, PITTET, Mikaël J, LAUMER, Monika, VOGL, Sandra, HEYMANN, Jana, REHLI, Michael, SELIGER, Barbara, SCHWARZ, Stephan, LE GAL, Frederique-Anne

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Cutting Edge: Cross-Presentation as a Mechanism for Efficient Recruitment of Tumor-Specific CTL to the Brain von Calzascia, Thomas, Di Berardino-Besson, Wilma, Wilmotte, Rick, Masson, Frederick, Tribolet, Nicolas de, Dietrich, Pierre-Yves, Walker, Paul R

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Degeneracy of antigen recognition as the molecular basis for the high frequency of naive A2/Melan-a peptide multimer(+) CD8(+) T cells in humans von Dutoit, Valérie, Rubio-Godoy, Verena, Pittet, Mikäel J, Zippelius, Alfred, Dietrich, Pierre-Yves, Legal, Frédérique Anne, Guillaume, Philippe, Romero, Pedro, Cerottini, Jean-Charles, Houghten, Richard A, Pinilla, Clemencia, Valmori, Danila

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Distinct structural TCR repertoires in naturally occurring versus vaccine-induced CD8+ T-cell responses to the tumor-specific antigen NY-ESO-1 von LE GAL, Frédérique-Anne, AYYOUB, Maha, DUTOIT, Valérie, WIDMER, Valérie, JÄGER, Elke, CEROTTINI, Jean-Charles, DIETRICH, Pierre-Yves, VALMORI, Danila

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Circulating tumor-reactive CD8+ T cells in melanoma patients contain a CD45RA+CCR7- effector subset exerting ex vivo tumor-specific cytolytic activity von VALMORI, Danila, SCHEIBENBOGEN, Carmen, LIPP, Martin, DIETRICH, Pierre-Yves, THIEL, Eckhard, CEROTTINI, Jean-Charles, LIENARD, Danielle, KEILHOLZ, Ulrich, DUTOIT, Valerie, NAGORSEN, Dirk, ASEMISSEN, Anne Marie, RUBIO-GODOY, Verena, RIMOLDI, Donata, GUILLAUME, Philippe, ROMERO, Pedro, SCHADENDORF, Dirk

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Vaccination with a Melan-A Peptide Selects an Oligoclonal T Cell Population with Increased Functional Avidity and Tumor Reactivity von Valmori, Danila, Dutoit, Valerie, Schnuriger, Valerie, Quiquerez, Anne-Lise, Pittet, Mikael J, Guillaume, Philippe, Rubio-Godoy, Verena, Walker, Paul R, Rimoldi, Donata, Lienard, Danielle, Cerottini, Jean-Charles, Romero, Pedro, Dietrich, Pierre-Yves

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All in the head: obstacles for immune rejection of brain tumours von Walker, Paul R., Calzascia, Thomas, Dietrich, Pierre‐Yves

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