Non-lethal Inhibition of Gut Microbial Trimethylamine Production for the Treatment of Atherosclerosis von Wang, Zeneng, Roberts, Adam B., Buffa, Jennifer A., Levison, Bruce S., Zhu, Weifei, Org, Elin, Gu, Xiaodong, Huang, Ying, Zamanian-Daryoush, Maryam, Culley, Miranda K., DiDonato, Anthony J., Fu, Xiaoming, Hazen, Jennie E., Krajcik, Daniel, DiDonato, Joseph A., Lusis, Aldons J., Hazen, Stanley L.

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A Cardiovascular Disease-Linked Gut Microbial Metabolite Acts via Adrenergic Receptors von Nemet, Ina, Saha, Prasenjit Prasad, Gupta, Nilaksh, Zhu, Weifei, Romano, Kymberleigh A., Skye, Sarah M., Cajka, Tomas, Mohan, Maradumane L., Li, Lin, Wu, Yuping, Funabashi, Masanori, Ramer-Tait, Amanda E., Naga Prasad, Sathyamangla Venkata, Fiehn, Oliver, Rey, Federico E., Tang, W.H. Wilson, Fischbach, Michael A., DiDonato, Joseph A., Hazen, Stanley L.

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Gut Microbial Metabolite TMAO Enhances Platelet Hyperreactivity and Thrombosis Risk von Zhu, Weifei, Gregory, Jill C., Org, Elin, Buffa, Jennifer A., Gupta, Nilaksh, Wang, Zeneng, Li, Lin, Fu, Xiaoming, Wu, Yuping, Mehrabian, Margarete, Sartor, R. Balfour, McIntyre, Thomas M., Silverstein, Roy L., Tang, W.H. Wilson, DiDonato, Joseph A., Brown, J. Mark, Lusis, Aldons J., Hazen, Stanley L.

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Long-Term Changes in Gut Microbial Metabolite Trimethylamine N-Oxide and Coronary Heart Disease Risk von Heianza, Yoriko, Ma, Wenjie, DiDonato, Joseph A., Sun, Qi, Rimm, Eric B., Hu, Frank B., Rexrode, Kathryn M., Manson, JoAnn E., Qi, Lu

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Development of a gut microbe–targeted nonlethal therapeutic to inhibit thrombosis potential von Roberts, Adam B., Gu, Xiaodong, Buffa, Jennifer A., Hurd, Alex G., Wang, Zeneng, Zhu, Weifei, Gupta, Nilaksh, Skye, Sarah M., Cody, David B., Levison, Bruce S., Barrington, William T., Russell, Matthew W., Reed, Jodie M., Duzan, Ashraf, Lang, Jennifer M., Fu, Xiaoming, Li, Lin, Myers, Alex J., Rachakonda, Suguna, DiDonato, Joseph A., Brown, J. Mark, Gogonea, Valentin, Lusis, Aldons J., Garcia-Garcia, Jose Carlos, Hazen, Stanley L.

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l-Carnitine in omnivorous diets induces an atherogenic gut microbial pathway in humans von Koeth, Robert A, Lam-Galvez, Betzabe Rachel, Kirsop, Jennifer, Wang, Zeneng, Levison, Bruce S, Gu, Xiaodong, Copeland, Matthew F, Bartlett, David, Cody, David B, Dai, Hong J, Culley, Miranda K, Li, Xinmin S, Fu, Xiaoming, Wu, Yuping, Li, Lin, DiDonato, Joseph A, Tang, W H Wilson, Garcia-Garcia, Jose Carlos, Hazen, Stanley L

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Targeted Inhibition of Gut Microbial Trimethylamine N-Oxide Production Reduces Renal Tubulointerstitial Fibrosis and Functional Impairment in a Murine Model of Chronic Kidney Disea... von Gupta, Nilaksh, Buffa, Jennifer A., Roberts, Adam B., Sangwan, Naseer, Skye, Sarah M., Li, Lin, Ho, Karen J., Varga, John, DiDonato, Joseph A., Tang, W.H. Wilson, Hazen, Stanley L.

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Intestinal microbiota metabolism of l-carnitine, a nutrient in red meat, promotes atherosclerosis von Koeth, Robert A, Wang, Zeneng, Levison, Bruce S, Buffa, Jennifer A, Org, Elin, Sheehy, Brendan T, Britt, Earl B, Fu, Xiaoming, Wu, Yuping, Li, Lin, Smith, Jonathan D, DiDonato, Joseph A, Chen, Jun, Li, Hongzhe, Wu, Gary D, Lewis, James D, Warrier, Manya, Brown, J Mark, Krauss, Ronald M, Tang, W H Wilson, Bushman, Frederic D, Lusis, Aldons J, Hazen, Stanley L

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γ-Butyrobetaine Is a Proatherogenic Intermediate in Gut Microbial Metabolism of L-Carnitine to TMAO von Koeth, Robert A., Levison, Bruce S., Culley, Miranda K., Buffa, Jennifer A., Wang, Zeneng, Gregory, Jill C., Org, Elin, Wu, Yuping, Li, Lin, Smith, Jonathan D., Tang, W.H. Wilson, DiDonato, Joseph A., Lusis, Aldons J., Hazen, Stanley L.

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Gut flora metabolism of phosphatidylcholine promotes cardiovascular disease von Wang, Zeneng, Klipfell, Elizabeth, Bennett, Brian J., Koeth, Robert, Levison, Bruce S., DuGar, Brandon, Feldstein, Ariel E., Britt, Earl B., Fu, Xiaoming, Chung, Yoon-Mi, Wu, Yuping, Schauer, Phil, Smith, Jonathan D., Allayee, Hooman, Tang, W. H. Wilson, DiDonato, Joseph A., Lusis, Aldons J., Hazen, Stanley L.

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Vascular endothelial tissue factor contributes to trimethylamine N-oxide-enhanced arterial thrombosis von Witkowski, Marco, Witkowski, Mario, Friebel, Julian, Buffa, Jennifer A, Li, Xinmin S, Wang, Zeneng, Sangwan, Naseer, Li, Lin, DiDonato, Joseph A, Tizian, Caroline, Haghikia, Arash, Kirchhofer, Daniel, Mach, François, Räber, Lorenz, Matter, Christian M, Tang, W H Wilson, Landmesser, Ulf, Lüscher, Thomas F, Rauch, Ursula, Hazen, Stanley L

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Site-specific Nitration of Apolipoprotein A-I at Tyrosine 166 Is Both Abundant within Human Atherosclerotic Plaque and Dysfunctional von DiDonato, Joseph A., Aulak, Kulwant, Huang, Ying, Wagner, Matthew, Gerstenecker, Gary, Topbas, Celalettin, Gogonea, Valentin, DiDonato, Anthony J., Tang, W.H.Wilson, Mehl, Ryan A., Fox, Paul L., Plow, Edward F., Smith, Jonathan D., Fisher, Edward A., Hazen, Stanley L.

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NF-κB and the link between inflammation and cancer von DiDonato, Joseph A., Mercurio, Frank, Karin, Michael

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The Cardioprotective Protein Apolipoprotein A1 Promotes Potent Anti-tumorigenic Effects von Zamanian-Daryoush, Maryam, Lindner, Daniel, Tallant, Thomas C., Wang, Zeneng, Buffa, Jennifer, Klipfell, Elizabeth, Parker, Yvonne, Hatala, Denise, Parsons-Wingerter, Patricia, Rayman, Pat, Yusufishaq, Mohamed Sharif S., Fisher, Edward A., Smith, Jonathan D., Finke, Jim, DiDonato, Joseph A., Hazen, Stanley L.

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Cancer Stem Cell‐Specific Scavenger Receptor CD36 Drives Glioblastoma Progression von Hale, James S., Otvos, Balint, Sinyuk, Maksim, Alvarado, Alvaro G., Hitomi, Masahiro, Stoltz, Kevin, Wu, Qiulian, Flavahan, William, Levison, Bruce, Johansen, Mette L., Schmitt, David, Neltner, Janna M., Huang, Ping, Ren, Bin, Sloan, Andrew E., Silverstein, Roy L., Gladson, Candece L., DiDonato, Joseph A., Brown, J. Mark, McIntyre, Thomas, Hazen, Stanley L., Horbinski, Craig, Rich, Jeremy N., Lathia, Justin D.

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Protein carbamylation links inflammation, smoking, uremia and atherogenesis von Wang, Zeneng, Barnard, John, DiDonato, Joseph A, Topol, Eric J, Nicholls, Stephen J, Rodriguez, E Rene, Hazen, Stanley L, Kummu, Outi, Reynolds, Wanda F, Hörkkö, Sohvi

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Modification of High Density Lipoprotein by Myeloperoxidase Generates a Pro-inflammatory Particle von Undurti, Arundhati, Huang, Ying, Lupica, Joseph A., Smith, Jonathan D., DiDonato, Joseph A., Hazen, Stanley L.

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Agonist of Toll-Like Receptor 5 Has Radioprotective Activity in Mouse and Primate Models von Burdelya, Lyudmila G, Krivokrysenko, Vadim I, Tallant, Thomas C, Strom, Evguenia, Gleiberman, Anatoly S, Gupta, Damodar, Kurnasov, Oleg V, Fort, Farrel L, Osterman, Andrei L, DiDonato, Joseph A, Feinstein, Elena, Gudkov, Andrei V

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Pulsed-electromagnetic-field induced osteoblast differentiation requires activation of genes downstream of adenosine receptors A2A and A3 von Kar, Niladri S, Ferguson, Daniel, Zhang, Nianli, Waldorff, Erik I, Ryaby, James T, DiDonato, Joseph A

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Gut Microbiota-Generated Phenylacetylglutamine and Heart Failure von Romano, Kymberleigh A., Nemet, Ina, Prasad Saha, Prasenjit, Haghikia, Arash, Li, Xinmin S., Mohan, Maradumane L., Lovano, Beth, Castel, Laurie, Witkowski, Marco, Buffa, Jennifer A., Sun, Yu, Li, Lin, Menge, Christopher M., Demuth, Ilja, König, Maximilian, Steinhagen-Thiessen, Elisabeth, DiDonato, Joseph A., Deb, Arjun, Bäckhed, Fredrik, Tang, W.H. Wilson, Naga Prasad, Sathyamangla Venkata, Landmesser, Ulf, Van Wagoner, David R., Hazen, Stanley L.

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