Liquid Biopsies: Genotyping Circulating Tumor DNA von DIAZ, Luis A, BARDELLI, Alberto

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Phase II Open-Label Study of Pembrolizumab in Treatment-Refractory, Microsatellite Instability-High/Mismatch Repair-Deficient Metastatic Colorectal Cancer: KEYNOTE-164 von Le, Dung T., Kim, Tae Won, Van Cutsem, Eric, Geva, Ravit, Jager, Dirk, Hara, Hiroki, Burge, Matthew, O'Neil, Bert, Kavan, Petr, Yoshino, Takayuki, Guimbaud, Rosine, Taniguchi, Hiroya, Elez, Elena, Al-Batran, Salah-Eddin, Boland, Patrick M., Crocenzi, Todd, Atreya, Chloe E., Cui, Yi, Dai, Tong, Marinello, Patricia, Diaz, Luis A., Andre, Thierry

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Pembrolizumab in Microsatellite-Instability–High Advanced Colorectal Cancer von André, Thierry, Shiu, Kai-Keen, Kim, Tae Won, Jensen, Benny Vittrup, Jensen, Lars Henrik, Punt, Cornelis, Smith, Denis, Garcia-Carbonero, Rocio, Benavides, Manuel, Gibbs, Peter, de la Fouchardiere, Christelle, Rivera, Fernando, Elez, Elena, Bendell, Johanna, Le, Dung T, Yoshino, Takayuki, Van Cutsem, Eric, Yang, Ping, Farooqui, Mohammed Z.H, Marinello, Patricia, Diaz, Luis A

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Immunotherapy in colorectal cancer: rationale, challenges and potential von Ganesh, Karuna, Stadler, Zsofia K., Cercek, Andrea, Mendelsohn, Robin B., Shia, Jinru, Segal, Neil H., Diaz, Luis A.

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Eradication of metastatic mouse cancers resistant to immune checkpoint blockade by suppression of myeloid-derived cells von Kim, KiBem, Skora, Andrew D., Li, Zhaobo, Liu, Qiang, Tam, Ada J., Blosser, Richard L., Diaz, Luis A., Papadopoulos, Nickolas, Kinzler, Kenneth W., Vogelstein, Bert, Zhou, Shibin

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Heteroplasmic mitochondrial DNA mutations in normal and tumour cells von Vogelstein, Bert, Papadopoulos, Nickolas, He, Yiping, Wu, Jian, Dressman, Devin C, Iacobuzio-Donahue, Christine, Markowitz, Sanford D, Velculescu, Victor E, Diaz Jr, Luis A, Kinzler, Kenneth W

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The Spectrum of Benefit from Checkpoint Blockade in Hypermutated Tumors von Rousseau, Benoit, Foote, Michael B, Maron, Steven B, Diplas, Bill H, Lu, Steve, Argilés, Guillem, Cercek, Andrea, Diaz, Luis A

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Cancer Genome Landscapes von Vogelstein, Bert, Papadopoulos, Nickolas, Velculescu, Victor E., Zhou, Shibin, Diaz, Luis A., Kinzler, Kenneth W.

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The molecular evolution of acquired resistance to targeted EGFR blockade in colorectal cancers von Diaz Jr, Luis A., Williams, Richard T., Wu, Jian, Kinde, Isaac, Hecht, J. Randolph, Berlin, Jordan, Allen, Benjamin, Bozic, Ivana, Reiter, Johannes G., Nowak, Martin A., Kinzler, Kenneth W., Oliner, Kelly S., Vogelstein, Bert

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Circulating mutant DNA to assess tumor dynamics von Sokoll, Lori, Li, Meng, Agrawal, Nishant, Thornton, Katherine, Schmidt, Kerstin, Szabo, Steve A, Vogelstein, Bert, Diaz Jr, Luis A, Diehl, Frank, Romans, Katharine, Choti, Michael A, Goodman, Steven, Kinzler, Kenneth W

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Mismatch Repair Deficiency and Response to Immune Checkpoint Blockade von Lee, Valerie, Murphy, Adrian, Le, Dung T., Diaz, Luis A.

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Whole-exome sequencing of neoplastic cysts of the pancreas reveals recurrent mutations in components of ubiquitin-dependent pathways von Wu, Jian, Jiao, Yuchen, Dal Molin, Marco, Maitra, Anirban, de Wilde, Roeland F, Wood, Laura D, Eshleman, James R, Goggins, Michael G, Wolfgang, Christopher L, Canto, Marcia I, Schulick, Richard D, Edil, Barish H, Choti, Michael A, Adsay, Volkan, Klimstra, David S, Offerhaus, G. Johan A, Klein, Alison P, Kopelovich, Levy, Carter, Hannah, Karchin, Rachel, Allen, Peter J, Schmidt, C. Max, Naito, Yoshiki, Diaz, Luis A. Jr, Kinzler, Kenneth W, Papadopoulos, Nickolas, Hruban, Ralph H, Vogelstein, Bert

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The genomic landscape of response to EGFR blockade in colorectal cancer von Bertotti, Andrea, Papp, Eniko, Jones, Siân, Adleff, Vilmos, Anagnostou, Valsamo, Lupo, Barbara, Sausen, Mark, Phallen, Jillian, Hruban, Carolyn A., Tokheim, Collin, Niknafs, Noushin, Nesselbush, Monica, Lytle, Karli, Sassi, Francesco, Cottino, Francesca, Migliardi, Giorgia, Zanella, Eugenia R., Ribero, Dario, Russolillo, Nadia, Mellano, Alfredo, Muratore, Andrea, Paraluppi, Gianluca, Salizzoni, Mauro, Marsoni, Silvia, Kragh, Michael, Lantto, Johan, Cassingena, Andrea, Li, Qing Kay, Karchin, Rachel, Scharpf, Robert, Sartore-Bianchi, Andrea, Siena, Salvatore, Diaz, Luis A., Trusolino, Livio, Velculescu, Victor E.

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From neoadjuvant to organ-sparing immunotherapy for colorectal cancer von Rousseau, Benoit, Cercek, Andrea, Diaz, Luis A.

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DAXX/ATRX, MEN1, and mTOR Pathway Genes Are Frequently Altered in Pancreatic Neuroendocrine Tumors von Jiao, Yuchen, Shi, Chanjuan, Edil, Barish H, de Wilde, Roeland F, Klimstra, David S, Maitra, Anirban, Schulick, Richard D, Tang, Laura H, Wolfgang, Christopher L, Choti, Michael A, Velculescu, Victor E, Diaz, Luis A. Jr, Vogelstein, Bert, Kinzler, Kenneth W, Hruban, Ralph H, Papadopoulos, Nickolas

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Pembrolizumab versus chemotherapy for microsatellite instability-high or mismatch repair-deficient metastatic colorectal cancer (KEYNOTE-177): final analysis of a randomised, open-... von Diaz, Luis A, Shiu, Kai-Keen, Kim, Tae-Won, Jensen, Benny Vittrup, Jensen, Lars Henrik, Punt, Cornelis, Smith, Denis, Garcia-Carbonero, Rocio, Benavides, Manuel, Gibbs, Peter, de la Fourchardiere, Christelle, Rivera, Fernando, Elez, Elena, Le, Dung T, Yoshino, Takayuki, Zhong, Wen Yan, Fogelman, David, Marinello, Patricia, Andre, Thierry

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Glucose Deprivation Contributes to the Development of KRAS Pathway Mutations in Tumor Cells von Yun, Jihye, Rago, Carlo, Cheong, Ian, Pagliarini, Ray, Angenendt, Philipp, Rajagopalan, Harith, Schmidt, Kerstin, Willson, James K.V, Markowitz, Sandy, Zhou, Shibin, Diaz, Luis A. Jr, Velculescu, Victor E, Lengauer, Christoph, Kinzler, Kenneth W, Vogelstein, Bert, Papadopoulos, Nickolas

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Primary Resistance to PD-1 Blockade Mediated by JAK1/2 Mutations von Shin, Daniel Sanghoon, Zaretsky, Jesse M, Escuin-Ordinas, Helena, Garcia-Diaz, Angel, Hu-Lieskovan, Siwen, Kalbasi, Anusha, Grasso, Catherine S, Hugo, Willy, Sandoval, Salemiz, Torrejon, Davis Y, Palaskas, Nicolaos, Rodriguez, Gabriel Abril, Parisi, Giulia, Azhdam, Ariel, Chmielowski, Bartosz, Cherry, Grace, Seja, Elizabeth, Berent-Maoz, Beata, Shintaku, I Peter, Le, Dung T, Pardoll, Drew M, Diaz, Jr, Luis A, Tumeh, Paul C, Graeber, Thomas G, Lo, Roger S, Comin-Anduix, Begoña, Ribas, Antoni

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Health-related quality of life in patients with microsatellite instability-high or mismatch repair deficient metastatic colorectal cancer treated with first-line pembrolizumab vers... von Andre, Thierry, Amonkar, Mayur, Norquist, Josephine M, Shiu, Kai-Keen, Kim, Tae Won, Jensen, Benny Vittrup, Jensen, Lars Henrik, Punt, Cornelis J A, Smith, Denis, Garcia-Carbonero, Rocio, Sevilla, Isabel, De La Fouchardiere, Christelle, Rivera, Fernando, Elez, Elena, Diaz, Luis A, Yoshino, Takayuki, Van Cutsem, Eric, Yang, Ping, Farooqui, Mohammed, Le, Dung T

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DNA Sensing in Mismatch Repair-Deficient Tumor Cells Is Essential for Anti-tumor Immunity von Lu, Changzheng, Guan, Junhong, Lu, Steve, Jin, Qihuang, Rousseau, Benoit, Lu, Tianshi, Stephens, Dennis, Zhang, Hongyi, Zhu, Jiankun, Yang, Mingming, Ren, Zhenhua, Liang, Yong, Liu, Zhida, Han, Chuanhui, Liu, Longchao, Cao, Xuezhi, Zhang, Anli, Qiao, Jian, Batten, Kimberly, Chen, Mingyi, Castrillon, Diego H., Wang, Tao, Li, Bo, Diaz, Luis A., Li, Guo-Min, Fu, Yang-Xin

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