Metabolic modelling of polyhydroxyalkanoate copolymers production by mixed microbial cultures von Dias, João M L, Oehmen, Adrian, Serafim, Luísa S, Lemos, Paulo C, Reis, Maria A M, Oliveira, Rui

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Towards better understanding of an industrial cell factory: investigating the feasibility of real-time metabolic flux analysis in Pichia pastoris von Fazenda, Mariana L, Dias, Joao M L, Harvey, Linda M, Nordon, Alison, Edrada-Ebel, Ruan, Littlejohn, David, McNeil, Brian

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Dynamic metabolic modelling of volatile fatty acids conversion to polyhydroxyalkanoates by a mixed microbial culture von Pardelha, Filipa, Albuquerque, Maria G.E., Reis, Maria A.M., Oliveira, Rui, Dias, João M.L.

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Mathematical modelling of a mixed culture cultivation process for the production of polyhydroxybutyrate von Dias, J.M.L, Serafim, L.S, Lemos, P.C, Reis, M.A.M, Oliveira, R

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Modeling NOM removal by softening in a surface water treatment plant von Dias, João M L, Oliveira, Rui, Semmens, Michael

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In situ 2D fluorometry and chemometric monitoring of mammalian cell cultures von Teixeira, Ana P, Portugal, Carla A.M, Carinhas, Nuno, Dias, João M.L, Crespo, João P, Alves, Paula M, Carrondo, M.J.T, Oliveira, Rui

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Projection to latent pathways method for elementary flux modes discrimination von Ferreira, Ana R, Dias, Joao ML, Teixeira, Ana P, Carinhas, Nuno, Portela, Rui MC, Isidro, Ines A, von Stosch, Moritz, Oliveira, Rui

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Cell functional enviromics: unravelling the function of environmental factors von Teixeira, Ana P, Dias, João Ml, Carinhas, Nuno, Sousa, Marcos, Clemente, João J, Cunha, António E, von Stosch, Moritz, Alves, Paula M, Carrondo, Manuel Jt, Oliveira, Rui

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Projection to latent pathways (PLP): a constrained projection to latent variables (PLS) method for elementary flux modes discrimination von Ferreira, Ana R, Dias, João M L, Teixeira, Ana P, Carinhas, Nuno, Portela, Rui M C, Isidro, Inês A, von Stosch, Moritz, Oliveira, Rui

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Small-molecule inhibition of METTL3 as a strategy against myeloid leukaemia von Yankova, Eliza, Blackaby, Wesley, Albertella, Mark, Rak, Justyna, De Braekeleer, Etienne, Tsagkogeorga, Georgia, Pilka, Ewa S, Aspris, Demetrios, Leggate, Dan, Hendrick, Alan G, Webster, Natalie A, Andrews, Byron, Fosbeary, Richard, Guest, Patrick, Irigoyen, Nerea, Eleftheriou, Maria, Gozdecka, Malgorzata, Dias, Joao ML, Bannister, Andrew J, Vick, Binje, Jeremias, Irmela, Vassiliou, George S, Rausch, Oliver, Tzelepis, Konstantinos, Kouzarides, Tony

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Dramatic response of metastatic cutaneous angiosarcoma to an immune checkpoint inhibitor in a patient with xeroderma pigmentosum: whole-genome sequencing aids treatment decision in... von Momen, Sophie, Fassihi, Hiva, Davies, Helen R, Nikolaou, Christos, Degasperi, Andrea, Stefanato, Catherine M, Dias, Joao ML, Dasgupta, Dhruba, Craythorne, Emma, Sarkany, Robert, Papa, Sophie, Nik-Zainal, Serena

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Glutaminolysis is a metabolic dependency in FLT3ITD acute myeloid leukemia unmasked by FLT3 tyrosine kinase inhibition von Gallipoli, Paolo, Giotopoulos, George, Tzelepis, Konstantinos, Costa, Ana SH, Vohra, Shabana, Medina-Perez, Paula, Basheer, Faisal, Marando, Ludovica, Di Lisio, Lorena, Dias, Joao ML, Yun, Haiyang, Sasca, Daniel, Horton, Sarah J, Vassiliou, George, Frezza, Christian, Huntly, Brian JP

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SRPK1 maintains acute myeloid leukemia through effects on isoform usage of epigenetic regulators including BRD4 von Tzelepis, Konstantinos, De Braekeleer, Etienne, Aspris, Demetrios, Barbieri, Isaia, Vijayabaskar, MS, Liu, Wen-Hsin, Gozdecka, Malgorzata, Metzakopian, Emmanouil, Toop, Hamish D, Dudek, Monika, Robson, Samuel C, Hermida-Prado, Francisco, Yang, Yu Hsuen, Babaei-Jadidi, Roya, Garyfallos, Dimitrios A, Ponstingl, Hannes, Dias, Joao ML, Gallipoli, Paolo, Seiler, Michael, Buonamici, Silvia, Vick, Binje, Bannister, Andrew J, Rad, Roland, Prinjha, Rab K, Marioni, John C, Huntly, Brian, Batson, Jennifer, Morris, Jonathan C, Pina, Cristina, Bradley, Allan, Jeremias, Irmela, Bates, David O, Yusa, Kosuke, Kouzarides, Tony, Vassiliou, George S

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Insights from multi-omic modeling of neurodegeneration in xeroderma pigmentosum using an induced pluripotent stem cell system von Badja, Cherif, Momen, Sophie, Koh, Gene Ching Chiek, Boushaki, Soraya, Roumeliotis, Theodoros I, Kozik, Zuza, Jones, Ian, Bousgouni, Vicky, Dias, João ML, Krokidis, Marios G, Young, Jamie, Chen, Hongwei, Yang, Ming, Docquier, France, Memari, Yasin, Valcarcel-Zimenez, Lorea, Gupta, Komal, Kong, Li Ren, Fawcett, Heather, Robert, Florian, Zhao, Salome, Degasperi, Andrea, Kumar, Yogesh, Davies, Helen, Harris, Rebecca, Frezza, Christian, Chatgilialoglu, Chryssostomos, Sarkany, Robert, Lehmann, Alan, Bakal, Chris, Choudhary, Jyoti, Fassihi, Hiva, Nik-Zainal, Serena

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Substitution mutational signatures in whole-genome-sequenced cancers in the UK population von Degasperi, Andrea, Zou, Xueqing, Amarante, Tauanne Dias, Martinez-Martinez, Andrea, Koh, Gene Ching Chiek, Dias, João ML, Heskin, Laura, Chmelova, Lucia, Rinaldi, Giuseppe, Wang, Valerie Ya Wen, Nanda, Arjun S, Bernstein, Aaron, Momen, Sophie E, Young, Jamie, Perez-Gil, Daniel, Memari, Yasin, Badja, Cherif, Shooter, Scott, Czarnecki, Jan, Brown, Matthew A, Davies, Helen R, Genomics England Research Consortium, Nik-Zainal, Serena

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Targeting the DNA Damage Response Pathways and Replication Stress in Colorectal Cancer von Durinikova, Erika, Reilly, Nicole M, Buzo, Kristi, Mariella, Elisa, Chilà, Rosaria, Lorenzato, Annalisa, Dias, João ML, Grasso, Gaia, Pisati, Federica, Lamba, Simona, Corti, Giorgio, Degasperi, Andrea, Cancelliere, Carlotta, Mauri, Gianluca, Andrei, Pietro, Linnebacher, Michael, Marsoni, Silvia, Siena, Salvatore, Sartore-Bianchi, Andrea, Nik-Zainal, Serena, Di Nicolantonio, Federica, Bardelli, Alberto, Arena, Sabrina

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Analysis of T cell receptor clonotypes in tumor microenvironment identifies shared cancer-type-specific signatures von Teng, Yvonne HF, Quah, Hong Sheng, Suteja, Lisda, Dias, João ML, Mupo, Annalisa, Bashford-Rogers, Rachael JM, Vassiliou, George S, Chua, Melvin LK, Tan, Daniel SW, Lim, Darren WT, Iyer, N Gopalakrishna

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Preclinical In Vivo Validation of the RAD51 Test for Identification of Homologous Recombination-Deficient Tumors and Patient Stratification von Pellegrino, Benedetta, Herencia-Ropero, Andrea, Llop-Guevara, Alba, Pedretti, Flaminia, Moles-Fernández, Alejandro, Viaplana, Cristina, Villacampa, Guillermo, Guzmán, Marta, Rodríguez, Olga, Grueso, Judit, Jiménez, Jose, Arenas, Enrique J, Degasperi, Andrea, Dias, João ML, Forment, Josep V, O'Connor, Mark J, Déas, Olivier, Cairo, Stefano, Zhou, Yinghui, Musolino, Antonino, Caldas, Carlos, Nik-Zainal, Serena, Clarke, Robert B, Nuciforo, Paolo, Díez, Orland, Serres-Créixams, Xavier, Peg, Vicente, Espinosa-Bravo, Martín, Macarulla, Teresa, Oaknin, Ana, Mateo, Joaquin, Arribas, Joaquín, Dienstmann, Rodrigo, Bellet, Meritxell, Oliveira, Mafalda, Saura, Cristina, Gutiérrez-Enríquez, Sara, Balmaña, Judith, Serra, Violeta

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Genetic modification of primary human B cells to model high-grade lymphoma von Caeser, Rebecca, Di Re, Miriam, Krupka, Joanna A, Gao, Jie, Lara-Chica, Maribel, Dias, João ML, Cooke, Susanna L, Fenner, Rachel, Usheva, Zelvera, Runge, Hendrik FP, Beer, Philip A, Eldaly, Hesham, Pak, Hyo-Kyung, Park, Chan-Sik, Vassiliou, George S, Huntly, Brian JP, Mupo, Annalisa, Bashford-Rogers, Rachael JM, Hodson, Daniel J

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Development and validation of a comprehensive genomic diagnostic tool for myeloid malignancies von McKerrell, Thomas, Moreno, Thaidy, Ponstingl, Hannes, Bolli, Niccolo, Dias, João ML, Tischler, German, Colonna, Vincenza, Manasse, Bridget, Bench, Anthony, Bloxham, David, Herman, Bram, Fletcher, Danielle, Park, Naomi, Quail, Michael A, Manes, Nicla, Hodkinson, Clare, Baxter, Joanna, Sierra, Jorge, Foukaneli, Theodora, Warren, Alan J, Chi, Jianxiang, Costeas, Paul, Rad, Roland, Huntly, Brian, Grove, Carolyn, Ning, Zemin, Tyler-Smith, Chris, Varela, Ignacio, Scott, Mike, Nomdedeu, Josep, Mustonen, Ville, Vassiliou, George S

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