Axon degeneration: mechanistic insights lead to therapeutic opportunities for the prevention and treatment of peripheral neuropathy von DiAntonio, Aaron

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SARM1 acts downstream of neuroinflammatory and necroptotic signaling to induce axon degeneration von Ko, Kwang Woo, Milbrandt, Jeffrey, DiAntonio, Aaron

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The SARM1 axon degeneration pathway: control of the NAD+ metabolome regulates axon survival in health and disease von Figley, Matthew D, DiAntonio, Aaron

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SIK3 and Wnk converge on Fray to regulate glial K+ buffering and seizure susceptibility von Lones, Lorenzo, DiAntonio, Aaron

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NMNAT1 inhibits axon degeneration via blockade of SARM1-mediated NAD + depletion von Sasaki, Yo, Nakagawa, Takashi, Mao, Xianrong, DiAntonio, Aaron, Milbrandt, Jeffrey

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SARM1 activation triggers axon degeneration locally via NAD+destruction von Gerdts, Josiah, Brace, E.J., Sasaki, Yo, DiAntonio, Aaron, Milbrandt, Jeffrey

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Axon Self-Destruction: New Links among SARM1, MAPKs, and NAD+ Metabolism von Gerdts, Josiah, Summers, Daniel W., Milbrandt, Jeffrey, DiAntonio, Aaron

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Live imaging reveals the cellular events downstream of SARM1 activation von Ko, Kwang Woo, Devault, Laura, Sasaki, Yo, Milbrandt, Jeffrey, DiAntonio, Aaron

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Protein phosphatase 2A restrains DLK signaling to promote proper Drosophila synaptic development and mammalian cortical neuron survival von Hayne, Margaret, DiAntonio, Aaron

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Dynamic regulation of SCG10 in regenerating axons after injury von Shin, Jung Eun, Geisler, Stefanie, DiAntonio, Aaron

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TIR Domain Proteins Are an Ancient Family of NAD+-Consuming Enzymes von Essuman, Kow, Summers, Daniel W., Sasaki, Yo, Mao, Xianrong, Yim, Aldrin Kay Yuen, DiAntonio, Aaron, Milbrandt, Jeffrey

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Sarm1-mediated axon degeneration requires both SAM and TIR interactions von Gerdts, Josiah, Summers, Daniel W, Sasaki, Yo, DiAntonio, Aaron, Milbrandt, Jeffrey

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Palmitoylation enables MAPK-dependent proteostasis of axon survival factors von Summers, Daniel W., Milbrandt, Jeffrey, DiAntonio, Aaron

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Prevention of vincristine-induced peripheral neuropathy by genetic deletion of SARM1 in mice von Geisler, Stefanie, Doan, Ryan A, Strickland, Amy, Huang, Xin, Milbrandt, Jeffrey, DiAntonio, Aaron

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SARM1-specific motifs in the TIR domain enable NAD⁺ loss and regulate injury-induced SARM1 activation von Summers, Daniel W., Gibson, Daniel A., DiAntonio, Aaron, Milbrandt, Jeffrey

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DLK Activation Synergizes with Mitochondrial Dysfunction to Downregulate Axon Survival Factors and Promote SARM1-Dependent Axon Degeneration von Summers, Daniel W., Frey, Erin, Walker, Lauren J., Milbrandt, Jeffrey, DiAntonio, Aaron

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MAPK signaling promotes axonal degeneration by speeding the turnover of the axonal maintenance factor NMNAT2 von Walker, Lauren J, Summers, Daniel W, Sasaki, Yo, Brace, E J, Milbrandt, Jeffrey, DiAntonio, Aaron

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Glutamate Receptors At The Drosophila Neuromuscular Junction von Diantonio, Aaron

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Bidirectional regulation of glial potassium buffering - glioprotection versus neuroprotection von Li, Hailun, Lones, Lorenzo, DiAntonio, Aaron

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A SARM1-mitochondrial feedback loop drives neuropathogenesis in a Charcot-Marie-Tooth disease type 2A rat model von Sato-Yamada, Yurie, Strickland, Amy, Sasaki, Yo, Bloom, Joseph, DiAntonio, Aaron, Milbrandt, Jeffrey

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