A clinicopathological and molecular analysis of 200 traditional serrated adenomas von Bettington, Mark L, Walker, Neal I, Rosty, Christophe, Brown, Ian S, Clouston, Andrew D, McKeone, Diane M, Pearson, Sally-Ann, Klein, Kerenaftali, Leggett, Barbara A, Whitehall, Vicki LJ

Volltext

RNF43 and ZNRF3 are commonly altered in serrated pathway colorectal tumorigenesis von Bond, Catherine E, McKeone, Diane M, Kalimutho, Murugan, Bettington, Mark L, Pearson, Sally-Ann, Dumenil, Troy D, Wockner, Leesa F, Burge, Matthew, Leggett, Barbara A, Whitehall, Vicki L J

Volltext

The role of APC in WNT pathway activation in serrated neoplasia von Borowsky, Jennifer, Dumenil, Troy, Bettington, Mark, Pearson, Sally-Ann, Bond, Catherine, Fennell, Lochlan, Liu, Cheng, McKeone, Diane, Rosty, Christophe, Brown, Ian, Walker, Neal, Leggett, Barbara, Whitehall, Vicki

Volltext

Oncogenic BRAF mutation induces DNA methylation changes in a murine model for human serrated colorectal neoplasia von Bond, Catherine E., Liu, Cheng, Kawamata, Futoshi, McKeone, Diane M., Fernando, Winnie, Jamieson, Saara, Pearson, Sally-Ann, Kane, Alexandra, Woods, Susan L., Lannagan, Tamsin R. M., Somashekar, Roshini, Lee, Young, Dumenil, Troy, Hartel, Gunter, Spring, Kevin J., Borowsky, Jennifer, Fennell, Lochlan, Bettington, Mark, Lee, Jason, Worthley, Daniel L., Leggett, Barbara A., Whitehall, Vicki L. J.

Volltext

Alterations in signaling pathways that accompany spontaneous transition to malignancy in a mouse model of BRAF mutant microsatellite stable colorectal cancer von Kane, Alexandra M., Fennell, Lochlan J., Liu, Cheng, Borowsky, Jennifer, McKeone, Diane M., Bond, Catherine E., Kazakoff, Stephen, Patch, Ann-Marie, Koufariotis, Lambros T., Pearson, John, Waddell, Nicola, Leggett, Barbara A., Whitehall, Vicki L.J.

Volltext

Aspirin reduces the incidence of metastasis in a pre-clinical study of Braf mutant serrated colorectal neoplasia von Kane, Alexandra M., Liu, Cheng, Fennell, Lochlan J., McKeone, Diane M., Bond, Catherine E., Pollock, Pamela M., Young, Graeme, Leggett, Barbara A., Whitehall, Vicki L. J.

Volltext

Curcumin Chemoprevention Reduces the Incidence of Braf Mutant Colorectal Cancer in a Preclinical Study von Kane, Alexandra M., Liu, Cheng, Akhter, Dewan T., McKeone, Diane M., Bell, Craig A., Thurecht, Kristofer J., Leggett, Barbara A., Whitehall, Vicki L. J.

Volltext

Genome-wide DNA methylation analysis of formalin-fixed paraffin embedded colorectal cancer tissue von Dumenil, Troy D., Wockner, Leesa F., Bettington, Mark, McKeone, Diane M., Klein, Kerenaftali, Bowdler, Lisa M., Montgomery, Grant W., Leggett, Barbara A., Whitehall, Vicki L.J.

Volltext

Serrated tubulovillous adenoma of the large intestine von Bettington, Mark, Walker, Neal, Rosty, Christophe, Brown, Ian, Clouston, Andrew, McKeone, Diane, Pearson, Sally-Ann, Klein, Kerenaftali, Leggett, Barbara, Whitehall, Vicki

Volltext

GNAS mutations are present in colorectal traditional serrated adenomas, serrated tubulovillous adenomas and serrated adenocarcinomas with adverse prognostic features von Liu, Cheng, McKeone, Diane M, Walker, Neal I, Bettington, Mark L, Leggett, Barbara A, Whitehall, Vicki L J

Volltext

Oncogenic PIK3CA mutations in colorectal cancers and polyps von Whitehall, Vicki L.J., Rickman, Celestine, Bond, Catherine E., Ramsnes, Ingunn, Greco, Sonia A., Umapathy, Aarti, McKeone, Diane, Faleiro, Rebecca J., Buttenshaw, Ron L., Worthley, Daniel L., Nayler, Sam, Zhao, Zhen Zhen, Montgomery, Grant W., Mallitt, Kylie-Ann, Jass, Jeremy R., Matsubara, Nagahide, Notohara, Kenji, Ishii, Tatsuhiro, Leggett, Barbara A.

Volltext

Integrative Genome-Scale DNA Methylation Analysis of a Large and Unselected Cohort Reveals 5 Distinct Subtypes of Colorectal Adenocarcinomas von Fennell, Lochlan, Dumenil, Troy, Wockner, Leesa, Hartel, Gunter, Nones, Katia, Bond, Catherine, Borowsky, Jennifer, Liu, Cheng, McKeone, Diane, Bowdler, Lisa, Montgomery, Grant, Klein, Kerenaftali, Hoffmann, Isabell, Patch, Ann-Marie, Kazakoff, Stephen, Pearson, John, Waddell, Nicola, Wirapati, Pratyaksha, Lochhead, Paul, Imamura, Yu, Ogino, Shuji, Shao, Renfu, Tejpar, Sabine, Leggett, Barbara, Whitehall, Vicki

Volltext

Lynch Syndrome―Associated Breast Cancers: Clinicopathologic Characteristics of a Case Series from the Colon Cancer Family Registry von WASH, Michael D, BUCHANAN, Daniel D, JENKINS, Mark A, PHILLIPS, Kerry D, SUTHERS, Graeme K, GEORGE, Jill, GOLDBLATT, Jack, MUIR, Amanda, TUCKER, Kathy, PELZER, Elise, GATTAS, Michael R, WOODALL, Sonja, CUMMINGS, Margaret C, PARRY, Susan, MACRAE, Finlay A, HAILE, Robert W, BARON, John A, POTTER, John D, LE MARCHAND, Loic, BAPAT, Bharati, THIBODEAU, Stephen N, LINDOR, Noralane M, MCGUCKIN, Michael A, PEARSON, Sally-Ann, YOUNG, Joanne P, ARNOLD, Sven T, CLENDENNING, Mark, WALTERS, Rhiannon, MCKEONE, Diane M, SPURDLE, Amanda B, HOPPER, John L

Volltext

Comparative analysis of Illumina Mouse Methylation BeadChip and reduced-representation bisulfite sequencing for routine DNA methylation analysis von Fennell, Lochlan J., Hartel, Gunter, McKeone, Diane M., Bond, Catherine E., Kane, Alexandra, Leggett, Barbara A., Patch, Ann-Marie, Whitehall, Vicki L.J.

Volltext

Copy number profiles of paired primary and metastatic colorectal cancers von Kawamata, Futoshi, Patch, Ann-Marie, Nones, Katia, Bond, Catherine, McKeone, Diane, Pearson, Sally-Ann, Homma, Shigenori, Liu, Cheng, Fennell, Lochlan, Dumenil, Troy, Hartel, Gunter, Kobayasi, Nozomi, Yokoo, Hideki, Fukai, Moto, Nishihara, Hiroshi, Kamiyama, Toshiya, Burge, Matthew E, Karapetis, Christos S, Taketomi, Akinobu, Leggett, Barbara, Waddell, Nicola, Whitehall, Vicki

Volltext

RNF43 is mutated less frequently in Lynch Syndrome compared with sporadic microsatellite unstable colorectal cancers von Fennell, Lochlan J., Clendenning, Mark, McKeone, Diane M., Jamieson, Saara H., Balachandran, Samanthy, Borowsky, Jennifer, Liu, John, Kawamata, Futoshi, Bond, Catherine E., Rosty, Christophe, Burge, Matthew E., Buchanan, Daniel D., Leggett, Barbara A., Whitehall, Vicki L. J.

Volltext

MLH1–93 G/a polymorphism is associated with MLH1 promoter methylation and protein loss in dysplastic sessile serrated adenomas with BRAFV600E mutation von Fennell, Lochlan J, Jamieson, Saara, McKeone, Diane, Corish, Tracie, Rohdmann, Megan, Furner, Tori, Bettington, Mark, Liu, Cheng, Kawamata, Futoshi, Bond, Catherine, Van De Pols, Jolieke, Leggett, Barbara, Whitehall, Vicki

Volltext

Methylation and expression of the tumour suppressor, PRDM5, in colorectal cancer and polyp subgroups von Bond, Catherine E, Bettington, Mark L, Pearson, Sally-Ann, McKeone, Diane M, Leggett, Barbara A, Whitehall, Vicki L J

Volltext

Risk factors for colorectal cancer in patients with multiple serrated polyps: a cross-sectional case series from genetics clinics von Buchanan, Daniel D, Sweet, Kevin, Drini, Musa, Jenkins, Mark A, Win, Aung Ko, English, Dallas R, Walsh, Michael D, Clendenning, Mark, McKeone, Diane M, Walters, Rhiannon J, Roberts, Aedan, Pearson, Sally-Ann, Pavluk, Erika, Hopper, John L, Gattas, Michael R, Goldblatt, Jack, George, Jill, Suthers, Graeme K, Phillips, Kerry D, Woodall, Sonja, Arnold, Julie, Tucker, Kathy, Muir, Amanda, Field, Michael, Greening, Sian, Gallinger, Steven, Perrier, Renee, Baron, John A, Potter, John D, Haile, Robert, Frankel, Wendy, de la Chapelle, Albert, Macrae, Finlay, Rosty, Christophe, Walker, Neal I, Parry, Susan, Young, Joanne P

Volltext

Molecular, Pathologic, and Clinical Features of Early-Onset Endometrial Cancer: Identifying Presumptive Lynch Syndrome Patients von WALSH, Michael D, CUMMINGS, Margaret C, JASS, Jeremy R, SPURDLE, Amanda B, YOUNG, Joanne, OBERMAIR, Andreas, BUCHANAN, Daniel D, DAMBACHER, Wendy M, ARNOLD, Sven, MCKEONE, Diane, BYRNES, Rebecca, BARKER, Melissa A, LEGGETT, Barbara A, GATTAS, Michael

Volltext