Therapeutic potential of CD22-specific antibody-targeted chemotherapy using inotuzumab ozogamicin (CMC-544) for the treatment of acute lymphoblastic leukemia von DIJOSEPH, J. F, DOUGHER, M. M, ARMELLINO, D. C, EVANS, D. Y, DAMLE, N. K

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The oncofetal protein, 5T4, is a suitable target for antibody-guided anti-cancer chemotherapy with calicheamicin von BOGHAERT, E. R, SRIDHARAN, L, DOUGHER, M, DIJOSEPH, J. F, DAMLE, N. K, KHANDKE, K. M, ARMELLINO, D, RYAN, M. G, MYERS, K, HARROP, R, KUNZ, A, HAMANN, P. R, MARQUETTE, K

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Synthesis and SAR of bicyclic heteroaryl hydroxamic acid MMP and TACE inhibitors von Zask, A., Gu, Y., Albright, J.D., Du, X., Hogan, M., Levin, J.I., Chen, J.M., Killar, L.M., Sung, A., DiJoseph, J.F., Sharr, M.A., Roth, C.E., Skala, S., Jin, G., Cowling, R., Mohler, K.M., Barone, D., Black, R., March, C., Skotnicki, J.S.

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Antibody-targeted chemotherapy of B-cell lymphoma using calicheamicin conjugated to murine or humanized antibody against CD22 von DIJOSEPH, John F, POPPLEWELL, Andrew, ZINKEWICH-PEOTTI, Karen, STEPHENS, Sue, WEIR, Neil, DAMLE, Nitin K, TICKLE, Simon, LADYMAN, Heather, LAWSON, Alastair, KUNZ, Arthur, KHANDKE, Kiran, ARMELLINO, Douglas C, BOGHAERT, Erwin R, HAMANN, Philip R

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The discovery of anthranilic acid-based mmp inhibitors. Part 3: incorporation of basic amines von Levin, J.I, Chen, J.M, Du, M.T, Nelson, F.C, Wehr, T, DiJoseph, J.F, Killar, L.M, Skala, S, Sung, A, Sharr, M.A, Roth, C.E, Jin, G, Cowling, R, Di, L, Sherman, M, Xu, Z.B, March, C.J, Mohler, K.M, Black, R.A, Skotnicki, J.S

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The discovery of anthranilic acid-based MMP inhibitors. Part 2: SAR of the 5-position and P1(1) groups von Levin, J I, Chen, J, Du, M, Hogan, M, Kincaid, S, Nelson, F C, Venkatesan, A M, Wehr, T, Zask, A, DiJoseph, J, Killar, L M, Skala, S, Sung, A, Sharr, M, Roth, C, Jin, G, Cowling, R, Mohler, K M, Black, R A, March, C J, Skotnicki, J S

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THE EFFECT OF RAPAMYCIN ON KIDNEY-FUNCTION IN THE SPRAGUE-DAWLEY RAT von DIJOSEPH, JF, SHARMA, RN, CHANG, JY

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The synthesis and biological activity of a novel series of diazepine MMP inhibitors von Levin, Jeremy I., DiJoseph, John F., Killar, Loran M., Sung, Amy, Walter, Thomas, Sharr, Michele A., Roth, Catherine E., Skotnicki, Jerauld S., Albright, J.Donald

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Therapeutic blood levels of sirolimus (rapamycin) in the allografted rat von DIJOSEPH, J. F, FLUHLER, E, ARMSRONG, J, SHARR, M, SEHGAL, S. N

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CD20-specific antibody-targeted chemotherapy of non-Hodgkin's B-cell lymphoma using calicheamicin-conjugated rituximab von Dijoseph, John F, Dougher, Maureen M, Armellino, Douglas C, Kalyandrug, Lyka, Kunz, Arthur, Boghaert, Erwin R, Hamann, Philip R, Damle, Nitin K

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The discovery of anthranilic acid-based MMP inhibitors. Part 1: SAR of the 3-position von LEVIN, Jeremy I, DU, Mila T, GUIXIAN JIN, COWLING, Rebecca, SKOTNICKI, Jerauld S, DIJOSEPH, John F, KILLAR, Loran M, SUNG, Amy, WALTER, Thomas, SHARR, Michele A, ROTH, Catherine E, MOY, Franklin J, POWERS, Robert

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Antibody-targeted chemotherapy with CMC-544: a CD22-targeted immunoconjugate of calicheamicin for the treatment of B-lymphoid malignancies von DiJoseph, John F., Armellino, Douglas C., Boghaert, Erwin R., Khandke, Kiran, Dougher, Maureen M., Sridharan, Latha, Kunz, Arthur, Hamann, Philip R., Gorovits, Boris, Udata, Chandrasekhar, Moran, Justin K., Popplewell, Andrew G., Stephens, Sue, Frost, Philip, Damle, Nitin K.

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Antitumor Efficacy of a Combination of CMC-544 (Inotuzumab Ozogamicin), a CD22-Targeted Cytotoxic Immunoconjugate of Calicheamicin, and Rituximab against Non-Hodgkin's B-Cell Lymph... von DIJOSEPH, John F, DOUGHER, Maureen M, KALYANDRUG, Lyka B, ARMELLINO, Douglas C, BOGHAERT, Erwin R, HAMANN, Philip R, MORAN, Justin K, DAMLE, Nitin K

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Malonyl α-mercaptoketones and α-mercaptoalcohols, a new class of matrix metalloproteinase inhibitors von Campbell, David A., Xiao, Xiao-Yi, Harris, David, Ida, Satoru, Mortezaei, Reza, Ngu, Khehyong, Shi, Lihong, Tien, David, Wang, Yongwen, Navre, Marc, Patel, Dinesh V., Sharr, Michele A., DiJoseph, John F., Killar, Loran M., Leone, Christina L., Levin, Jeremy I., Skotnicki, Jerauld S.

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The asymmetric synthesis and in vitro characterization of succinyl mercaptoalcohol and mercaptoketone inhibitors of matrix metalloproteinases von Levin, Jeremy I., DiJoseph, John F., Killar, Loran M., Sharr, Michele A., Skotnicki, Jerauld S., Patel, Dinesh V., Xiao, Xiao-Yi, Shi, Lihong, Navre, Marc, Campbell, David A.

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Heteroaryl and cycloalkyl sulfonamide hydroxamic acid inhibitors of matrix metalloproteinases von LEVIN, Jeremy I, YANSONG GU, COSMI, Scott, HSIAO, Chu-Lai, EDRIS, Wade, WILHELM, James, KILLAR, Loran M, SKOTNICKI, Jerauld S, NELSON, Frances C, ZASK, Arie, DIJOSEPH, John F, SHARR, Michele A, SUNG, Amy, GUIXIAN JIN, COWLING, Rebecca, CHANDA, Pranab

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The discovery of anthranilic acid-based MMP inhibitors. Part 2 : SAR of the 5-position and P11 groups von LEVIN, J. I, CHEN, J, KILLAR, L. M, SKALA, S, SUNG, A, SHARR, M, ROTH, C, JIN, G, COWLING, R, MOHLER, K. M, BLACK, R. A, MARCH, C. J, DU, M, SKOTNICKI, J. S, HOGAN, M, KINCAID, S, NELSON, F. C, VENKATESAN, A. M, WEHR, T, ZASK, A, DIJOSEPH, J

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Renal effects of rapamycin in the spontaneously hypertensive rat von DiJoseph, John F., Mihatsch, Michael J., Sehgal, Suren N.

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Potent and Specific Antitumor Efficacy of CMC-544, a CD22-Targeted Immunoconjugate of Calicheamicin, against Systemically Disseminated B-Cell Lymphoma von DIJOSEPH, John F, GOAD, Mary E, DOUGHER, Maureen M, BOGHAERT, Erwin R, KUNZ, Arthur, HAMANN, Philip R, DAMLE, Nitin K

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Activated aluminum complex derived from solubilized antacids exhibits enhanced cytoprotective activity in the rat von DiJoseph, John F., Borella, Luis E., Mir, G.Nabi

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