HDACs, histone deacetylation and gene transcription: from molecular biology to cancer therapeutics von Gallinari, Paola, Marco, Stefania Di, Jones, Phillip, Pallaoro, Michele, Steinkühler, Christian

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The crystal structure of the quorum sensing protein TraR bound to its autoinducer and target DNA von Vannini, Alessandro, Volpari, Cinzia, Gargioli, Cesare, Muraglia, Ester, Cortese, Riccardo, De Francesco, Raffaele, Neddermann, Petra, Di Marco, Stefania

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A third generation vaccine for human visceral leishmaniasis and post kala azar dermal leishmaniasis: First-in-human trial of ChAd63-KH von Osman, Mohamed, Mistry, Anoop, Keding, Ada, Gabe, Rhian, Cook, Elizabeth, Forrester, Sarah, Wiggins, Rebecca, Di Marco, Stefania, Colloca, Stefano, Siani, Loredana, Cortese, Riccardo, Smith, Deborah F, Aebischer, Toni, Kaye, Paul M, Lacey, Charles J

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Crystal Structure of a Eukaryotic Zinc-Dependent Histone Deacetylase, Human HDAC8, Complexed with a Hydroxamic Acid Inhibitor von Vannini, Alessandro, Volpari, Cinzia, Filocamo, Gessica, Casavola, Elena Caroli, Brunetti, Mirko, Renzoni, Debora, Chakravarty, Prasun, Paolini, Chantal, De Francesco, Raffaele, Gallinari, Paola, Steinkühler, Christian, Di Marco, Stefania, Kim, Peter S.

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Substrate binding to histone deacetylases as shown by the crystal structure of the HDAC8-substrate complex von Vannini, Alessandro, Volpari, Cinzia, Gallinari, Paola, Jones, Philip, Mattu, Marco, Carfí, Andrea, De Francesco, Raffaele, Steinkühler, Christian, Di Marco, Stefania

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Chronic hepatitis C viral infection subverts vaccine‐induced T‐cell immunity in humans von Kelly, Christabel, Swadling, Leo, Capone, Stefania, Brown, Anthony, Richardson, Rachel, Halliday, John, von Delft, Annette, Oo, Ye, Mutimer, David, Kurioka, Ayako, Hartnell, Felicity, Collier, Jane, Ammendola, Virginia, Sorbo, Mariarosaria Del, Grazioli, Fabiana, Esposito, Maria Luisa, Marco, Stefania Di, Siani, Loredana, Traboni, Cinzia, Hill, Adrian V.S., Colloca, Stefano, Nicosia, Alfredo, Cortese, Riccardo, Folgori, Antonella, Klenerman, Paul, Barnes, Eleanor

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Optimization of Thienopyrrole‐Based Finger‐Loop Inhibitors of the Hepatitis C Virus NS5B Polymerase von Martin Hernando, Jose Ignacio, Ontoria, Jesus Maria, Malancona, Savina, Attenni, Barbara, Fiore, Fabrizio, Bonelli, Fabio, Koch, Uwe, Di Marco, Stefania, Colarusso, Stefania, Ponzi, Simona, Gennari, Nadia, Vignetti, Sue Ellen, del Rosario Rico Ferreira, Maria, Habermann, Jörg, Rowley, Michael, Narjes, Frank

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The three-dimensional structure of caspase-8: an initiator enzyme in apoptosis von Blanchard, Helen, Kodandapani, Lalitha, Mittl, Peer RE, Marco, Stefania Di, Krebs, Joseph F, Wu, Joe C, Tomaselli, Kevin J, Grütter, Markus G

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PCSK9-binding antibody that structurally mimics the EGF(A) domain of LDL-receptor reduces LDL cholesterol in vivo von Ni, Yan G, Di Marco, Stefania, Condra, Jon H, Peterson, Laurence B, Wang, Weirong, Wang, Fubao, Pandit, Shilpa, Hammond, Holly A, Rosa, Ray, Cummings, Richard T, Wood, Dana D, Liu, Xiaomei, Bottomley, Matthew J, Shen, Xun, Cubbon, Rose M, Wang, Sheng-ping, Johns, Douglas G, Volpari, Cinzia, Hamuro, Lora, Chin, Jayne, Huang, Lingyi, Zhao, Jing Zhang, Vitelli, Salvatore, Haytko, Peter, Wisniewski, Douglas, Mitnaul, Lyndon J, Sparrow, Carl P, Hubbard, Brian, Carfí, Andrea, Sitlani, Ayesha

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Adenovirus DNA Polymerase Loses Fidelity on a Stretch of Eleven Homocytidines during Pre-GMP Vaccine Preparation von Hannoun, Zara, Wee, Edmund G., Crook, Alison, Colloca, Stefano, Di Marco, Stefania, Hanke, Tomáš

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Interdomain Communication in Hepatitis C Virus Polymerase Abolished by Small Molecule Inhibitors Bound to a Novel Allosteric Site von Di Marco, Stefania, Volpari, Cinzia, Tomei, Licia, Altamura, Sergio, Harper, Steven, Narjes, Frank, Koch, Uwe, Rowley, Michael, De Francesco, Raffaele, Migliaccio, Giovanni, Carfí, Andrea

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Human vaccination against RH5 induces neutralizing antimalarial antibodies that inhibit RH5 invasion complex interactions von Payne, Ruth O, Silk, Sarah E, Elias, Sean C, Miura, Kazutoyo, Diouf, Ababacar, Galaway, Francis, de Graaf, Hans, Brendish, Nathan J, Poulton, Ian D, Griffiths, Oliver J, Edwards, Nick J, Jin, Jing, Labbé, Geneviève M, Alanine, Daniel Gw, Siani, Loredana, Di Marco, Stefania, Roberts, Rachel, Green, Nicky, Berrie, Eleanor, Ishizuka, Andrew S, Nielsen, Carolyn M, Bardelli, Martino, Partey, Frederica D, Ofori, Michael F, Barfod, Lea, Wambua, Juliana, Murungi, Linda M, Osier, Faith H, Biswas, Sumi, McCarthy, James S, Minassian, Angela M, Ashfield, Rebecca, Viebig, Nicola K, Nugent, Fay L, Douglas, Alexander D, Vekemans, Johan, Wright, Gavin J, Faust, Saul N, Hill, Adrian Vs, Long, Carole A, Lawrie, Alison M, Draper, Simon J

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Nucleic Acid Binding of the RTN1-C C-Terminal Region: Toward the Functional Role of a Reticulon Protein von Melino, Sonia, Nepravishta, Ridvan, Bellomaria, Alessia, Di Marco, Stefania, Paci, Maurizio

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Studies on the Mode of Ku Interaction with DNA von Arosio, Daniele, Cui, Sheng, Ortega, Claudia, Chovanec, Miroslav, Di Marco, Stefania, Baldini, Giancarlo, Falaschi, Arturo, Vindigni, Alessandro

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Safety and immunogenicity of ChAdOx1 nCoV-19 vaccine administered in a prime-boost regimen in young and old adults (COV002): a single-blind, randomised, controlled, phase 2/3 trial von Folegatti, Pedro M, Bibi, Sagida, Chappell, Harry, Fedosyuk, Sofiya, Gbesemete, Diane, Kelly, Elizabeth J, Makinson, Rebecca, Rawlinson, Thomas, Ross-Russell, Amy L, Saich, Stephen, Smith, Catherine C, Tarrant, Richard, Thomas, Kelly M, Warren, Sarah C, Lambe, Teresa, Adams, Kelly, Ali, Aabidah, Allen, Lauren, Baker, Natalie, Barrett, Kelly, Bellamy, Duncan, Berg, Adam, Beveridge, Amy, Bewley, Kevin, Bijker, Else M., Boland, Elena, Bormans, Daan, Bower, Thomas, Boyd, Amy, Brenner, Tanja, Buttigieg, Karen R., Cao, Michelangelo, Chapman, David, Chelysheva, Irina, Cifuentes, Liliana, Collins, Sarah, Conlon, Christopher P., Davis, Judith, Dong, Tao, Drake, Jonathan, Fisher, Richard, Garlant, Harriet, Gavrila, Madita, Gibbons, Felicity, Gill, Hardeep, Hart, Thomas C., Hartnell, Birgit, Haskell, Louise, Hawkins, Sophia, Hermosin Herrera, Macarena, Hill, David, Hill, Jennifer, Howes, Jessica, Jackson, Susan, Joshi, Amar, Kelly, Dearbhla M., King, Lloyd D.W., Knott, Daniel, Lee, Kim Y.N., Leung, Stephanie, Liu, Shuchang, Loew, Lisa, Madhavan, Meera, Marius, Phedra, Marshall, Julia L., Martin, Jane, Moore, Maria, Morris, Susan J., O'Reilly, Peter John, Owino, Nelly, Patel, Bhumika, Patrick-Smith, Maia, Perring, James, Phillips, Daniel J., Poulton, Ian, Presland, Laura, Pulido, David, Rajapaska, Durga, Ramos Lopez, Fernando, Rollier, Christine S., Romani, Rossana, Sedik, Cynthia, Seddiqi, Samiullah, Segireddy, Rameswara R., Sharpe, Hannah R., Silva-Reyes, Laura, Smith, David J., Smith, Daniel C., Smith, Nicholas, Stockley, David, Summerton, Eloise, Szigeti, Anna, Taylor, Ursula, Tonks, Susan, Tree, Julian A., Truby, Adam, Varughese, Rachel, Woodyer, Mark, Worth, Andrew T., Yao, Xin Li

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Crystal Structure of the Quorum-sensing Protein TraM and Its Interaction with the Transcriptional Regulator TraR von Vannini, Alessandro, Volpari, Cinzia, Di Marco, Stefania

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Structure of Recombinant Human CPP32 in Complex with the Tetrapeptide Acetyl-Asp-Val-Ala-Asp Fluoromethyl Ketone von Mittl, Peer R.E., Di Marco, Stefania, Krebs, Joseph F., Bai, Xu, Karanewsky, Donald S., Priestle, John P., Tomaselli, Kevin J., Grütter, Markus G.

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The Design and Enzyme-Bound Crystal Structure of Indoline Based Peptidomimetic Inhibitors of Hepatitis C Virus NS3 Protease von Ontoria, Jesus M, Di Marco, Stefania, Conte, Immacolata, Di Francesco, M. Emilia, Gardelli, Cristina, Koch, Uwe, Matassa, Victor G, Poma, Marco, Steinkühler, Christian, Volpari, Cinzia, Harper, Steven

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A PCSK9-binding antibody that structurally mimics the EGF(A) domain of LDL-receptor reduces LDL cholesterol in vivo1[S] von Ni, Yan G., Di Marco, Stefania, Condra, Jon H., Peterson, Laurence B., Wang, Weirong, Wang, Fubao, Pandit, Shilpa, Hammond, Holly A., Rosa, Ray, Cummings, Richard T., Wood, Dana D., Liu, Xiaomei, Bottomley, Matthew J., Shen, Xun, Cubbon, Rose M., Wang, Sheng-ping, Johns, Douglas G., Volpari, Cinzia, Hamuro, Lora, Chin, Jayne, Huang, Lingyi, Zhao, Jing Zhang, Vitelli, Salvatore, Haytko, Peter, Wisniewski, Douglas, Mitnaul, Lyndon J., Sparrow, Carl P., Hubbard, Brian, Carfí, Andrea, Sitlani, Ayesha

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A Monovalent Chimpanzee Adenovirus Ebola Vaccine Boosted with MVA von Ewer, Katie, Rampling, Tommy, Venkatraman, Navin, Bowyer, Georgina, Wright, Danny, Lambe, Teresa, Imoukhuede, Egeruan B, Payne, Ruth, Fehling, Sarah Katharina, Strecker, Thomas, Biedenkopf, Nadine, Krähling, Verena, Tully, Claire M, Edwards, Nick J, Bentley, Emma M, Samuel, Dhanraj, Labbé, Geneviève, Jin, Jing, Gibani, Malick, Minhinnick, Alice, Wilkie, Morven, Poulton, Ian, Lella, Natalie, Roberts, Rachel, Hartnell, Felicity, Bliss, Carly, Sierra-Davidson, Kailan, Powlson, Jonathan, Berrie, Eleanor, Tedder, Richard, Roman, Francois, De Ryck, Iris, Nicosia, Alfredo, Sullivan, Nancy J, Stanley, Daphne A, Mbaya, Olivier T, Ledgerwood, Julie E, Schwartz, Richard M, Siani, Loredana, Colloca, Stefano, Folgori, Antonella, Di Marco, Stefania, Cortese, Riccardo, Wright, Edward, Becker, Stephan, Graham, Barney S, Koup, Richard A, Levine, Myron M, Volkmann, Ariane, Chaplin, Paul, Pollard, Andrew J, Draper, Simon J, Ballou, W. Ripley, Lawrie, Alison, Gilbert, Sarah C, Hill, Adrian V.S

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