Molecular Understanding of USP7 Substrate Recognition and C-Terminal Activation von Rougé, Lionel, Bainbridge, Travis W., Kwok, Michael, Tong, Raymond, Di Lello, Paola, Wertz, Ingrid E., Maurer, Till, Ernst, James A., Murray, Jeremy

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Design of Libraries Targeting Protein-Protein Interfaces von Fry, David, Huang, Kuo-Sen, Di Lello, Paola, Mohr, Peter, Müller, Klaus, So, Sung-Sau, Harada, Takeo, Stahl, Martin, Vu, Binh, Mauser, Harald

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A Conserved Amphipathic Helix in the N-Terminal Regulatory Region of the Papillomavirus E1 Helicase Is Required for Efficient Viral DNA Replication von MORIN, Geneviève, FRADET-TURCOTTE, Amelie, DI LELLO, Paola, BERGERON-LABRECQUE, Fanny, OMICHINSKI, James G, ARCHAMBAULT, Jacques

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Activation of the p53 pathway by small-molecule-induced MDM2 and MDMX dimerization von Graves, Bradford, Thompson, Thelma, Xia, Mingxuan, Janson, Cheryl, Lukacs, Christine, Deo, Dayanand, Di Lello, Paola, Fry, David, Garvie, Colin, Huang, Kuo-Sen, Gao, Lin, Tovar, Christian, Lovey, Allen, Wanner, Jutta, Vassilev, Lyubomir T

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Identification of a Small Peptide That Inhibits PCSK9 Protein Binding to the Low Density Lipoprotein Receptor von Zhang, Yingnan, Eigenbrot, Charles, Zhou, Lijuan, Shia, Steven, Li, Wei, Quan, Clifford, Tom, Jeffrey, Moran, Paul, Di Lello, Paola, Skelton, Nicholas J., Kong-Beltran, Monica, Peterson, Andrew, Kirchhofer, Daniel

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Functional and structural characterization of a dense core secretory granule sorting domain from the PC1/3 protease von Dikeakos, Jimmy D, Di Lello, Paola, Lacombe, Marie-Josée, Ghirlando, Rodolfo, Legault, Pascale, Reudelhuber, Timothy L, Omichinski, James G

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Discovery of a cryptic peptide-binding site on PCSK9 and design of antagonists von Zhang, Yingnan, Ultsch, Mark, Skelton, Nicholas J, Burdick, Daniel J, Beresini, Maureen H, Li, Wei, Kong-Beltran, Monica, Peterson, Andrew, Quinn, John, Chiu, Cecilia, Wu, Yan, Shia, Steven, Moran, Paul, Di Lello, Paola, Eigenbrot, Charles, Kirchhofer, Daniel

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Unveiling the Structural and Dynamic Nature of the Ubiquitin Code von Di Lello, Paola, Hymowitz, Sarah G.

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Structural and functional characterization of an atypical activation domain in erythroid Krüppel-like factor (EKLF) von Mas, Caroline, Lussier-Price, Mathieu, Soni, Shefali, Morse, Thomas, Arseneault, Geneviève, Di Lello, Paola, Lafrance-Vanasse, Julien, Bieker, James J., Omichinski, James G.

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Bioproduction Platform to Generate Functionalized Disulfide-Constrained Peptide Analogues von Hwang, Sunhee, Balana, Aaron T., Martin, Bryan, Clarkson, Michael, Di Lello, Paola, Wu, Hao, Li, Yanjie, Fuhrmann, Jakob, Dagdas, Yavuz, Holder, Patrick, Schroeder, Christina I., Miller, Stephen E., Gao, Xinxin

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Crystal Structures of the Organomercurial Lyase MerB in Its Free and Mercury-bound Forms: INSIGHTS INTO THE MECHANISM OF METHYLMERCURY DEGRADATION von Lafrance-Vanasse, Julien, Lefebvre, Maryse, Di Lello, Paola, Sygusch, Jurgen, Omichinski, James G

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p53 and TFIIEα Share a Common Binding Site on the Tfb1/p62 Subunit of TFIIH von Di Lello, Paola, Jenkins, Lisa M. Miller, Mas, Caroline, Langlois, Chantal, Malitskaya, Elena, Fradet-Turcotte, Amélie, Archambault, Jacques, Legault, Pascale, Omichinski, James G.

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NMR Structure of a Complex Formed by the Carboxyl-Terminal Domain of Human RAP74 and a Phosphorylated Peptide from the Central Domain of the FCP1 Phosphatase von Yang, Ao, Abbott, Karen L, Desjardins, Alexandre, Di Lello, Paola, Omichinski, James G, Legault, Pascale

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NMR Structure of the Amino-Terminal Domain from the Tfb1 Subunit of TFIIH and Characterization of Its Phosphoinositide and VP16 Binding Sites von Di Lello, Paola, Nguyen, Bao D, Jones, Tamara N, Potempa, Krzysztof, Kobor, Michael S, Legault, Pascale, Omichinski, James G

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A Stable Mercury-Containing Complex of the Organomercurial Lyase MerB:  Catalysis, Product Release, and Direct Transfer to MerA von Benison, Gregory C, Di Lello, Paola, Shokes, Jacob E, Cosper, Nathaniel J, Scott, Robert A, Legault, Pascale, Omichinski, James G

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Crystal Structures of the Organomercurial Lyase MerB in Its Free and Mercury-bound Forms von Lafrance-Vanasse, Julien, Lefebvre, Maryse, Di Lello, Paola, Sygusch, Jurgen, Omichinski, James G.

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NMR Structure of the Complex between the Tfb1 Subunit of TFIIH and the Activation Domain of VP16: Structural Similarities between VP16 and p53 von Langlois, Chantal, Mas, Caroline, Di Lello, Paola, Jenkins, Lisa M. Miller, Legault, Pascale, Omichinski, James G

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USP7 small-molecule inhibitors interfere with ubiquitin binding von Kategaya, Lorna, Di Lello, Paola, Rougé, Lionel, Pastor, Richard, Clark, Kevin R., Drummond, Jason, Kleinheinz, Tracy, Lin, Eva, Upton, John-Paul, Prakash, Sumit, Heideker, Johanna, McCleland, Mark, Ritorto, Maria Stella, Alessi, Dario R., Trost, Matthias, Bainbridge, Travis W., Kwok, Michael C. M., Ma, Taylur P., Stiffler, Zachary, Brasher, Bradley, Tang, Yinyan, Jaishankar, Priyadarshini, Hearn, Brian R., Renslo, Adam R., Arkin, Michelle R., Cohen, Frederick, Yu, Kebing, Peale, Frank, Gnad, Florian, Chang, Matthew T., Klijn, Christiaan, Blackwood, Elizabeth, Martin, Scott E., Forrest, William F., Ernst, James A., Ndubaku, Chudi, Wang, Xiaojing, Beresini, Maureen H., Tsui, Vickie, Schwerdtfeger, Carsten, Blake, Robert A., Murray, Jeremy, Maurer, Till, Wertz, Ingrid E.

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NMR Structural Studies Reveal a Novel Protein Fold for MerB, the Organomercurial Lyase Involved in the Bacterial Mercury Resistance System von Di Lello, Paola, Benison, Gregory C, Valafar, Homayoun, Pitts, Keith E, Summers, Anne O, Legault, Pascale, Omichinski, James G

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Discovery of Small-Molecule Inhibitors of Ubiquitin Specific Protease 7 (USP7) Using Integrated NMR and in Silico Techniques von Di Lello, Paola, Pastor, Richard, Murray, Jeremy M, Blake, Robert A, Cohen, Frederick, Crawford, Terry D, Drobnick, Joy, Drummond, Jason, Kategaya, Lorna, Kleinheinz, Tracy, Maurer, Till, Rougé, Lionel, Zhao, Xianrui, Wertz, Ingrid, Ndubaku, Chudi, Tsui, Vickie

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