Ex vivo gene modification therapy for genetic skin diseases—recent advances in gene modification technologies and delivery von Jayarajan, Vignesh, Kounatidou, Evangelia, Qasim, Waseem, Di, Wei‐Li

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Persistent kallikrein 5 activation induces atopic dermatitis-like skin architecture independent of PAR2 activity von Zhu, Yanan, PhD, Underwood, Joanne, PhD, Macmillan, Derek, PhD, Shariff, Leila, PhD, O'Shaughnessy, Ryan, PhD, Harper, John I., MD, FRCP, FRCPCH, Pickard, Chris, PhD, Friedmann, Peter S., MD, FRCP, FMedSci, Healy, Eugene, MB, PhD, FRCP, FRSB, Di, Wei-Li, MBBS, PhD

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Tissue Kallikrein Inhibitors Based on the Sunflower Trypsin Inhibitor Scaffold - A Potential Therapeutic Intervention for Skin Diseases von Chen, Wenjie, Kinsler, Veronica A, Macmillan, Derek, Di, Wei-Li

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Inflammatory Skin and Bowel Disease Linked to ADAM17 Deletion von Blaydon, Diana C, Biancheri, Paolo, Di, Wei-Li, Plagnol, Vincent, Cabral, Rita M, Brooke, Matthew A, van Heel, David A, Ruschendorf, Franz, Toynbee, Mark, Walne, Amanda, O'Toole, Edel A, Martin, Joanne E, Lindley, Keith, Vulliamy, Tom, Abrams, Dominic J, MacDonald, Thomas T, Harper, John I, Kelsell, David P

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Generation and Clinical Application of Gene-Modified Autologous Epidermal Sheets in Netherton Syndrome: Lessons Learned from a Phase 1 Trial von Di, Wei-Li, Lwin, Su M, Petrova, Anastasia, Bernadis, Catina, Syed, Farhatullah, Farzaneh, Farzin, Moulding, Dale, Martinez, Anna E, Sebire, Neil J, Rampling, Dyanne, Virasami, Alex, Zamiri, Mozheh, Wang, Wei, Hara, Havinder, Kadiyirire, Tendai, Abdul-Wahab, Alya, Martinez-Queipo, Magdalena, Harper, John I, McGrath, John A, Thrasher, Adrian J, Mellerio, Jemima E, Qasim, Waseem

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A mechanistic target of rapamycin complex 1/2 (mTORC1)/V-Akt murine thymoma viral oncogene homolog 1 (AKT1)/cathepsin H axis controls filaggrin expression and processing in skin, a... von Naeem, Aishath S., PhD, Tommasi, Cristina, MRes, Cole, Christian, PhD, Brown, Stuart J., PhD, Zhu, Yanan, PhD, Way, Benjamin, MA, BMBCh, MSc, MRCS, Willis Owen, Saffron A.G., DPhil, Moffatt, Miriam, DPhil, Cookson, William O., DPhil, Harper, John I., MBBS, MD, FRCP, FRCPCH, Di, Wei-Li, PhD, Brown, Sara J., MD, FRCPE, Reinheckel, Thomas, PhD, O'Shaughnessy, Ryan F.L., PhD

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Short-Term Treatment with Rho-Associated Kinase Inhibitor Preserves Keratinocyte Stem Cell Characteristics In Vitro von Jayarajan, Vignesh, Hall, George T, Xenakis, Theodoros, Bulstrode, Neil, Moulding, Dale, Castellano, Sergi, Di, Wei-Li

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Case Report: ISG15 deficiency caused by novel variants in two families and effective treatment with Janus kinase inhibition von Burleigh, Alice, Moraitis, Elena, Al Masroori, Eman, Al-Abadi, Eslam, Hong, Ying, Omoyinmi, Ebun, Titheradge, Hannah, Stals, Karen, Jones, Wendy D, Gait, Anthony, Jayarajan, Vignesh, Di, Wei-Li, Sebire, Neil, Solman, Lea, Ogboli, Malobi, Welch, Steven B, Sudarsanam, Annapurna, Wacogne, Ian, Price-Kuehne, Fiona, Jensen, Barbara, Brogan, Paul A, Eleftheriou, Despina

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Harlequin ichthyosis: ABCA12 mutations underlie defective lipid transport, reduced protease regulation and skin-barrier dysfunction von Scott, Claire A, Rajpopat, Shefali, Di, Wei-Li

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Cytosine Deaminase Base Editing to Restore COL7A1 in Dystrophic Epidermolysis Bullosa Human: Murine Skin Model von Naso, Gaetano, Gkazi, Soragia Athina, Georgiadis, Christos, Jayarajan, Vignesh, Jacków, Joanna, Fleck, Roland, Allison, Leanne, Ogunbiyi, Olumide Kayode, McGrath, John Alexander, Ilic, Dusko, Di, Wei-Li, Petrova, Anastasia, Qasim, Waseem

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Efficient CRISPR-Cas9-Mediated Gene Ablation in Human Keratinocytes to Recapitulate Genodermatoses: Modeling of Netherton Syndrome von Gálvez, Victoria, Chacón-Solano, Esteban, Bonafont, Jose, Mencía, Ángeles, Di, Wei-Li, Murillas, Rodolfo, Llames, Sara, Vicente, Asunción, Del Rio, Marcela, Carretero, Marta, Larcher, Fernando

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Selection of reference genes for RT-qPCR analysis of Phenacoccus solenopsis (Hemiptera: Pseudococcidae) sex-dimorphic development von ZHENG, Lu-ying, ZHANG, Zhi-jun, ZHANG, Jin-ming, LI, Xiao-wei, HUANG, Jun, LIN, Wen-cai, LI, Wei-di, LI, Chuan-ren, LU, Yao-bin

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New Role for LEKTI in Skin Barrier Formation: Label-Free Quantitative Proteomic Identification of Caspase 14 as a Novel Target for the Protease Inhibitor LEKTI von Bennett, Kate, Callard, Robin, Heywood, Wendy, Harper, John, Jayakumar, Arumugam, L.Clayman, Gary, Di, Wei-Li, Mills, Kevin

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Human Mesenchymal Stromal Cells Engineered to Express Collagen VII Can Restore Anchoring Fibrils in Recessive Dystrophic Epidermolysis Bullosa Skin Graft Chimeras von Petrova, Anastasia, Georgiadis, Christos, Fleck, Roland A., Allison, Leanne, McGrath, John A., Dazzi, Francesco, Di, Wei-Li, Qasim, Waseem

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Allele-Specific Small Interfering RNA Corrects Aberrant Cellular Phenotype in Keratitis-Ichthyosis-Deafness Syndrome Keratinocytes von Lee, Ming Yang, Wang, Hong-Zhan, White, Thomas W., Brooks, Tony, Pittman, Alan, Halai, Heerni, Petrova, Anastasia, Xu, Diane, Hart, Stephen L., Kinsler, Veronica A., Di, Wei-Li

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Molecular Genetic Dissection of Inflammatory Linear Verrucous Epidermal Naevus Leads to Successful Targeted Therapy von Riachi, Melissa, Polubothu, Satyamaanasa, Stadnik, Paulina, Hughes, Connor, Martin, Sara Barberan, Charman, Carolyn R., Cheng, Iek Leng, Gholam, Karolina, Ogunbiyi, Olumide, Paige, David G., Sebire, Neil J., Pittman, Alan, Di, Wei-Li, Kinsler, Veronica A.

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Sunflower trypsin inhibitor (SFTI-1) analogues of synthetic and biological origin via N→S acyl transfer: potential inhibitors of human Kallikrein-5 (KLK5) von Shariff, Leila, Zhu, Yanan, Cowper, Ben, Di, Wei-Li, Macmillan, Derek

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Feeding by Whiteflies Suppresses Downstream Jasmonic Acid Signaling by Eliciting Salicylic Acid Signaling von Zhang, Peng-Jun, Li, Wei-Di, Huang, Fang, Zhang, Jin-Ming, Xu, Fang-Cheng, Lu, Yao-Bin

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Connexin Mutations in Skin Disease and Hearing Loss von Kelsell, David P., Di, Wei-Li, Houseman, Mark J.

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Absence of γ-Chain in Keratinocytes Alters Chemokine Secretion, Resulting in Reduced Immune Cell Recruitment von Nowak, Karolin, Linzner, Daniela, Thrasher, Adrian J., Lambert, Paul F., Di, Wei-Li, Burns, Siobhan O.

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