113 Preclinical activity and pharmacodynamic biomarkers of W014A, a PD-1 decoy peptide blocking both PD-1 immune checkpoint ligands, PD-L1 and PD-L2 von Bailly, C, Broussas, M, Ramachandra, M, Sasikumar, P.G, Shrimali, K, Adurthi, S, Satyam, L.K, Dhudashia, A.A, Dhodheri, S, Sunilkumar, K.B, Corvaïa, N, Ferre, P

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ODM-203, a Selective Inhibitor of FGFR and VEGFR, Shows Strong Antitumor Activity, and Induces Antitumor Immunity von Holmström, Tim H, Moilanen, Anu-Maarit, Ikonen, Tarja, Björkman, Mari L, Linnanen, Tero, Wohlfahrt, Gerd, Karlsson, Stefan, Oksala, Riikka, Korjamo, Timo, Samajdar, Susanta, Rajagopalan, Srinivasan, Chelur, Shekar, Narayanan, Kishore, Ramachandra, Raghuveer K, Mani, Jiju, Nair, Rashmi, Gowda, Nagaraj, Anthony, Thomas, Dhodheri, Samiulla, Mukherjee, Subhendu, Ujjinamatada, Ravi K, Srinivas, Nanduri, Ramachandra, Murali, Kallio, Pekka J

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Abstract A96: First-in-class orally available immune checkpoint antagonists for cancer therapy von Sasikumar, Pottayil G., Naremaddepalli, Sudarshan S., Gowda, Nagaraj, Adurthi, Sreenivas, Dhodheri, Samiulla, Dhudashia, Amit, Ramachandra, Raghuveer, Ramachandra, Murali

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Debio 0617B Inhibits Growth of STAT3-Driven Solid Tumors through Combined Inhibition of JAK, SRC, and Class III/V Receptor Tyrosine Kinases von Murone, Maximilien, Vaslin Chessex, Anne, Attinger, Antoine, Ramachandra, Raghuveer, Shetty, Shankar J, Daginakatte, Girish, Sengupta, Saumitra, Marappan, Sivapriya, Dhodheri, Samiulla, Rigotti, Stefania, Bachhav, Yogeshwar, Brienza, Silvano, Traxler, Peter, Lang, Marc, Aguet, Michel, Zoete, Vincent, Michielin, Olivier, Nicholas, Courtney, Johnson, Faye M, Ramachandra, Murali, McAllister, Andres

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Abstract 5022: Peptide therapeutic inhibiting PD1 immune checkpoint ligands: Potential for greater anti-tumor immune response and better management of immune-related adverse events von Ramachandra, Murali, Sasikumar, Pottayil G., Shrimali, Rajeev K., Adurthi, Sreenivas, Ramachandra, Raghuvir, Satyam, Leena K., Dhudashia, Amit A., Dhodheri, Samiulla, Sunilkumar, K B.

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