Defining the Essential Function of Yeast Hsf1 Reveals a Compact Transcriptional Program for Maintaining Eukaryotic Proteostasis von Solís, Eric J., Pandey, Jai P., Zheng, Xu, Jin, Dexter X., Gupta, Piyush B., Airoldi, Edoardo M., Pincus, David, Denic, Vladimir

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Somatic HLA Class I Loss Is a Widespread Mechanism of Immune Evasion Which Refines the Use of Tumor Mutational Burden as a Biomarker of Checkpoint Inhibitor Response von Montesion, Meagan, Murugesan, Karthikeyan, Jin, Dexter X, Sharaf, Radwa, Sanchez, Nora, Guria, Ameet, Minker, Max, Li, Gerald, Fisher, Virginia, Sokol, Ethan S, Pavlick, Dean C, Moore, Jay A, Braly, Alan, Singal, Gaurav, Fabrizio, David, Comment, Leah A, Rizvi, Naiyer A, Alexander, Brian M, Frampton, Garrett M, Hegde, Priti S, Albacker, Lee A

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Cancer-specific PERK signaling drives invasion and metastasis through CREB3L1 von Feng, Yu-Xiong, Jin, Dexter X., Sokol, Ethan S., Reinhardt, Ferenc, Miller, Daniel H., Gupta, Piyush B.

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Comprehensive Genomic Profiling of Carcinoma of Unknown Primary Origin: Retrospective Molecular Classification Considering the CUPISCO Study Design von Ross, Jeffrey S., Sokol, Ethan S., Moch, Holger, Mileshkin, Linda, Baciarello, Giulia, Losa, Ferran, Beringer, Andreas, Thomas, Marlene, Elvin, Julia A., Ngo, Nhu, Jin, Dexter X., Krämer, Alwin

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Activating genomic alterations in the Gs alpha gene (GNAS) in 274 694 tumors von Tirosh, Amit, Jin, Dexter X., De Marco, Luiz, Laitman, Yael, Friedman, Eitan

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Tissue and liquid biopsy profiling reveal convergent tumor evolution and therapy evasion in breast cancer von Sivakumar, Smruthy, Jin, Dexter X., Tukachinsky, Hanna, Murugesan, Karthikeyan, McGregor, Kimberly, Danziger, Natalie, Pavlick, Dean, Gjoerup, Ole, Ross, Jeffrey S., Harmon, Robert, Chung, Jon, Decker, Brennan, Dennis, Lucas, Frampton, Garrett M., Molinero, Luciana, Oesterreich, Steffi, Venstrom, Jeffrey M., Oxnard, Geoffrey R., Hegde, Priti S., Sokol, Ethan S.

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Genomic profiling and comparative analysis of male versus female metastatic breast cancer across subtypes von Kadamkulam Syriac, Arun, Nandu, Nitish Singh, Clark, Allison, Tavallai, Mehrad, Jin, Dexter X, Sokol, Ethan, McGregor, Kimberly, Ross, Jeffrey S, Danziger, Natalie, Leone, Jose Pablo

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Epithelial-to-mesenchymal transition activates PERK-eIF2α and sensitizes cells to endoplasmic reticulum stress von Feng, Yu-Xiong, Sokol, Ethan S, Del Vecchio, Catherine A, Sanduja, Sandhya, Claessen, Jasper H L, Proia, Theresa A, Jin, Dexter X, Reinhardt, Ferenc, Ploegh, Hidde L, Wang, Qiu, Gupta, Piyush B

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Loss of Slug Compromises DNA Damage Repair and Accelerates Stem Cell Aging in Mammary Epithelium von Gross, Kayla M, Zhou, Wenhui, Breindel, Jerrica L, Ouyang, Jian, Jin, Dexter X, Sokol, Ethan S, Gupta, Piyush B, Huber, Kathryn, Zou, Lee, Kuperwasser, Charlotte

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Breast tissue regeneration is driven by cell-matrix interactions coordinating multi-lineage stem cell differentiation through DDR1 von Rauner, Gat, Jin, Dexter X., Miller, Daniel H., Gierahn, Todd M., Li, Carman M., Sokol, Ethan S., Feng, Yu-Xiong, Mathis, Robert A., Love, J. Christopher, Gupta, Piyush B., Kuperwasser, Charlotte

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The spectrum of tumors harboring BAP1 gene alterations von Laitman, Yael, Newberg, Justin, Molho, Rinat Bernstein, Jin, Dexter X., Friedman, Eitan

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Genetic Heterogeneity and Tissue-specific Patterns of Tumors with Multiple PIK3CA Mutations von Sivakumar, Smruthy, Jin, Dexter X, Rathod, Ruchita, Ross, Jeffrey, Cantley, Lewis C, Scaltriti, Maurizio, Chen, Jessica W, Hutchinson, Katherine E, Wilson, Timothy R, Sokol, Ethan S, Vasan, Neil

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Perturbation-expression analysis identifies RUNX1 as a regulator of human mammary stem cell differentiation von Sokol, Ethan S, Sanduja, Sandhya, Jin, Dexter X, Miller, Daniel H, Mathis, Robert A, Gupta, Piyush B

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Tumor sequencing of African ancestry reveals differences in clinically relevant alterations across common cancers von Jiagge, Evelyn, Jin, Dexter X., Newberg, Justin Y., Perea-Chamblee, Tomin, Pekala, Kelly R., Fong, Christopher, Waters, Michele, Ma, David, Dei-Adomakoh, Yvonne, Erb, Gilles, Arora, Kanika S., Maund, Sophia L., Njiraini, Njoki, Ntekim, Atara, Kim, Susie, Bai, Xuechun, Thomas, Marlene, van Eeden, Ronwyn, Hegde, Priti, Jee, Justin, Chakravarty, Debyani, Schultz, Nikolaus, Berger, Michael F., Frampton, Garrett M., Sokol, Ethan S., Carrot-Zhang, Jian

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Gene partners of the EWSR1 fusion may represent molecularly distinct entities von Walker, Victoria, Jin, Dexter X., Millis, Sherri Z., Nasri, Elham, Corao-Uribe, Diana A., Tan, Aik Choon, Fridley, Brooke L., Chen, James L., Seligson, Nathan D.

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Premature polyadenylation of MAGI3 is associated with diminished N6-methyladenosine in its large internal exon von Ni, Thomas K., Elman, Jessica S., Jin, Dexter X., Gupta, Piyush B., Kuperwasser, Charlotte

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Circulating Cell-Free DNA Yield and Circulating-Tumor DNA Quantity from Liquid Biopsies of 12 139 Cancer Patients von Huang, Richard S P, Xiao, Jinpeng, Pavlick, Dean C, Guo, Cui, Yang, Lei, Jin, Dexter X, Fendler, Bernard, Severson, Eric, Killian, Jonathan Keith, Hiemenz, Matthew, Duncan, Daniel, Lin, Douglas I, Dennis, Lucas, Aiyer, Aparna, Gjoerup, Ole, Oxnard, Geoff, Venstrom, Jeffrey, Elvin, Julia, Ramkissoon, Shakti H, Ross, Jeffrey S

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Identification of FUBP1 as a Long Tail Cancer Driver and Widespread Regulator of Tumor Suppressor and Oncogene Alternative Splicing von Elman, Jessica S., Ni, Thomas K., Mengwasser, Kristen E., Jin, Dexter, Wronski, Ania, Elledge, Stephen J., Kuperwasser, Charlotte

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Defining the Essential Function of Yeast Hsf1 Reveals a Compact Transcriptional Program for Maintaining Eukaryotic Proteostasis von Solís, Eric J., Pandey, Jai P., Zheng, Xu, Jin, Dexter X., Gupta, Piyush B., Airoldi, Edoardo M., Pincus, David, Denic, Vladimir

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Association of CD274 (PD-L1) Copy Number Changes with Immune Checkpoint Inhibitor Clinical Benefit in Non-Squamous Non-Small Cell Lung Cancer von Murugesan, Karthikeyan, Jin, Dexter X, Comment, Leah A, Fabrizio, David, Hegde, Priti S, Elvin, Julia A, Alexander, Brian, Levy, Mia A, Frampton, Garrett M, Montesion, Meagan, Roychowdhury, Sameek, Kurzrock, Razelle, Ross, Jeffrey S, Albacker, Lee A, Huang, Richard S P

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