1398 Immune responses and long-term survival with mRNA vaccine targeting diffuse midline glioma von Weidert, Frances, Roemeling, Christina Von, McGuiness, James, Chardon-Robles, Jonathan, Thomas, Nagheme, Devries, Anna, Qdaisat, Sadeem, Zhang, Dingpeng, Grippin, Adam, Karachi, Aida, Huang, Jianping, Rahman, Maryam, Ogando-Rivas, Elizabeth, Castillo, Paul, Hwang, Eugene, Mendez-Gomez, Hector, Staff, Study, Silver, Natalie, Ligon, John A, Sayour, Elias

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EXTH-76. REDIRECTING STROMAL CELLS TO IGNITE ANTI-TUMOR IMMUNITY AGAINST GLIOBLASTOMA von DeVries, Anna, von Roemeling, Christina, Moor, Rachel, Wummer, Brandon, Weidert, Frances, Chardon-Robles, Jonathan, Ligon, John, Castillo, Paul, Mendez-Gomez, Hector, Sayour, Elias

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EXTH-35. UNRAVELING THE MECHANISTIC UNDERPINNINGS OF MRNA VACCINE MEDIATED INNATE IMMUNE ACTIVATION AND LYMPHOCYTE TRAFFICKING FOR HIGH-GRADE GLIOMAS von DeVries, Anna, Mendez-Gomez, Hector, Chardon-Robles, Jonathan, Thomas, Nagheme, McGuiness, James, Carrera-Justiz, Sheila, Castillo, Paul, Weidert, Frances, Mitchell, Duane, Sayour, Elias

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RNA aggregates harness the danger response for potent cancer immunotherapy von Mendez-Gomez, Hector R., DeVries, Anna, Castillo, Paul, von Roemeling, Christina, Qdaisat, Sadeem, Stover, Brian D., Xie, Chao, Weidert, Frances, Zhao, Chong, Moor, Rachel, Liu, Ruixuan, Soni, Dhruvkumar, Ogando-Rivas, Elizabeth, Chardon-Robles, Jonathan, McGuiness, James, Zhang, Dingpeng, Chung, Michael C., Marconi, Christiano, Michel, Stephen, Barpujari, Arnav, Jobin, Gabriel W., Thomas, Nagheme, Ma, Xiaojie, Campaneria, Yodarlynis, Grippin, Adam, Karachi, Aida, Li, Derek, Sahay, Bikash, Elliott, Leighton, Foster, Timothy P., Coleman, Kirsten E., Milner, Rowan J., Sawyer, W. Gregory, Ligon, John A., Simon, Eugenio, Cleaver, Brian, Wynne, Kristine, Hodik, Marcia, Molinaro, Annette M., Guan, Juan, Kellish, Patrick, Doty, Andria, Lee, Ji-Hyun, Massini, Tara, Kresak, Jesse L., Huang, Jianping, Hwang, Eugene I., Kline, Cassie, Carrera-Justiz, Sheila, Rahman, Maryam, Gatica, Sebastian, Mueller, Sabine, Prados, Michael, Ghiaseddin, Ashley P., Silver, Natalie L., Mitchell, Duane A., Sayour, Elias J.

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CTIM-11. MRNA AGGREGATES ELICIT RAPID IMMUNOLOGIC RESPONSE AND PSEUDOPROGRESSION IN GLIOBLASTOMA PATIENTS von Ghiaseddin, Ashley, Mendez-Gomez, Hector, Rahman, Maryam, DeVries, Anna, Zhang, Dingpeng, Zhao, Chong, Hodik, Marcia, Kresak, Jesse, Massini, Tara, Gatica, Sebastian, Ligon, John, Castillo, Paul, Huang, Jianping, Silver, Natalie, Hwang, Eugene, Kline, Cassie, Mueller, Sabine, Prados, Michael, Mitchell, Duane, Sayour, Elias

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DIPG-18. MULTIMODALITY VISUALIZATION OF A PRECLINICAL MODEL OF DIFFUSE MIDLINE GLIOMA DEMONSTRATES CLEAR TREATMENT EFFECT AFTER RNA NANOPARTICLE THERAPY von Moor, Rachel, Weidert, Frances, von Roemeling, Christina, Robles, Jonathan Chardon, Merritt, Matthew, Rushin, Anna, Sharma, Guarav, McGuiness, James, Thomas, Nagheme, DeVries, Anna, Qdaisat, Sadeem, Zhang, Dingpeng, Rahman, Maryam, Ogando-Rivas, Elizabeth, Castillo, Paul, Ghiaseddin, Ashley, Carrera-Justiz, Sheila, Mitchell, Duane, Mendez-Gomez, Hector, Silver, Natalie, Ligon, John, Sayour, Elias

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IMMU-06. SYSTEMIC MRNA VACCINES RESET IMMUNOGENICITY AGAINST DIFFUSE MIDLINE GLIOMA von McGuiness, James, Weidert, Frances, DeVries, Anna, Ligon, John, Zhang, Dingpeng, Von Roemeling, Christina, Grippin, Adam, Karachi, Aida, Qdaisat, Sadeem, Thomas, Nagheme, Castillo, Paul, Huang, Jianping, Silver, Natalie, Rahman, Maryam, Hwang, Eugene, Mitchell, Duane, Mendez-Gomez, Hector, Sayour, Elias

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IMMU-63. MESSENGER RNA CHALLENGE PREDICTS CANCER IMMUNOGENICITY AND RESPONSE TO CHECKPOINT INHIBITORS von Castillo, Paul, Ogando-Rivas, Elizabeth, Geffrard, Hilary, Pepe, Alfonso, Nguyen, Duy, Pedro, Diego, Zhang, Dingpeng, DeVries, Anna, Qdaisat, Sadeem, Grippin, Adam, Rahman, Maryam, Weidert, Frances, Milner, Rowan, Huang, Jianping, Silver, Natalie, Ligon, John, Carrera-Justiz, Sheila, Mitchell, Duane, Mendez-Gomez, Hector, Sawyer, Gregory, Sayour, Elias

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IMMU-31. DAMAGE RESPONSE FROM SYSTEMIC RNA VACCINATION RESTORES HUMORAL IMMUNITY IN GLIOBLASTOMA von Moor, Rachel, Aghaee, Mahya, Carrera-Justiz, Sheila, Qdaisat, Sadeem, Xie, Chao, Soni, Dhruvkumar, von Roemeling, Christina, DeVries, Anna, Wummer, Brandon, Weidert, Frances, Chardon-Robles, Jonathan, Ligon, John, Castillo, Paul, Silver, Natalie, Kline, Cassie, Prados, Michael, Mueller, Sabine, Hwang, Eugene, Rahman, Maryam, Ghiaseddin, Ashley, Mitchell, Duane, Seligson, Nathan, Mendez-Gomez, Hector, Moore, Helen, Sayour, Elias

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IMMU-20. MESSENGER RNA CHALLENGE RAPIDLY PREDICTS BRAIN TUMOR RESPONSIVENESS TO CHECKPOINT INHIBITORS von Castillo, Paul, Ogando-Rivas, Elizabeth, Geffrard, Hillary, Pepe, Alfonso, Liu, Ruixuan, Nguyen, Duy, Pedro, Diego, Zhang, Dingpeng, DeVries, Anna, Qdaisat, Sadeem, Grippin, Adam, Karachi, Aida, Rahman, Maryam, Milner, Rowan, Huang, Jianping, Ligon, John, Silver, Natalie, Li, Derek, Lee, Ji-Hyun, Carrera-Justiz, Sheila, Weidert, Frances, Mitchell, Duane, Mendez-Gomez, Hector, Sawyer, W Gregory, Sayour, Elias

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CTIM-28. MULTILAMELLAR MRNA LIPID PARTICLES INDUCE IMMUNOLOGIC REPROGRAMMING IN CANINE AND HUMAN GLIOBLASTOMA PATIENTS von Mendez-Gomez, Hector, DeVries, Anna, Stover, Brian, Zhang, Dingpeng, Grippin, Adam, Von Roemeling, Christina, Weidert, Frances, Karachi, Aida, Qdaisat, Sadeem, Thomas, Nagheme, McGuiness, James, Castillo, Paul, Huang, Jianping, Ligon, John, Silver, Natalie, Kellish, Patrick, Doty, Andria, Carrera-Justiz, Sheila, Prados, Michael, Mueller, Sabine, Rahman, Maryam, Ghiaseddin, Ashley, Mitchell, Duane, Sayour, Elias

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Proof‐of‐concept of a data‐driven approach to estimate the associations of comorbid mental and physical disorders with global health‐related disability von Vries, Ymkje Anna, Alonso, Jordi, Chatterji, Somnath, Jonge, Peter, Lokkerbol, Joran, McGrath, John J., Petukhova, Maria V., Sampson, Nancy A., Sverdrup, Erik, Vigo, Daniel V., Wager, Stefan, Al‐Hamzawi, Ali, Borges, Guilherme, Bruffaerts, Ronny, Bunting, Brendan, Chardoul, Stephanie, Karam, Elie G., Kiejna, Andrzej, Kovess‐Masfety, Viviane, Navarro‐Mateu, Fernando, Ojagbemi, Akin, Piazza, Marina, Posada‐Villa, José, Sasu, Carmen, Scott, Kate M., Tachimori, Hisateru, Have, Margreet Ten, Torres, Yolanda, Viana, Maria Carmen, Zamparini, Manuel, Zarkov, Zahari, Kessler, Ronald C., Aguilar‐Gaxiola, Sergio, Altwaijri, Yasmin A., Andrade, Laura Helena, Atwoli, Lukoye, Benjet, Corina, Bromet, Evelyn J., Caldas‐de‐Almeida, Jose Miguel, Cardoso, Graça, Cía, Alfredo H., Degenhardt, Louisa, Girolamo, Giovanni, Gureje, Oye, Haro, Josep Maria, Harris, Meredith G., Hinkov, Hristo, Hu, Chi‐yi, Karam, Aimee Nasser, Karam, Georges, Kazdin, Alan E., Kawakami, Norito, Khaled, Salma, Medina‐Mora, Maria Elena, Moskalewicz, Jacek, Nishi, Daisuke, Stagnaro, Juan Carlos, Stein, Dan J., Vladescu, Cristian, Williams, David R., Wojtyniak, Bogdan, Woodruff, Peter, Xavier, Miguel, Zaslavsky, Alan M.

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The daytime feeding frequency affects appetite-regulating hormones, amino acids, physical activity, and respiratory quotient, but not energy expenditure, in adult cats fed regimens... von Camara, Alexandra, Verbrugghe, Adronie, Cargo-Froom, Cara, Hogan, Kylie, DeVries, Trevor J, Sanchez, Andrea, Robinson, Lindsay E, Shoveller, Anna K

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Functional aggregation of cell-free proteins enables fungal ice nucleation von Schwidetzky, Ralph, de Almeida Ribeiro, Ingrid, Bothen, Nadine, Backes, Anna T, DeVries, Arthur L, Bonn, Mischa, Fröhlich-Nowoisky, Janine, Molinero, Valeria, Meister, Konrad

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The development of a semisynthetic diet deficient in methionine for adult cats for controlled feline nutrition studies: effects on acceptability, preference, and behavior responses von Pezzali, Julia Guazzelli, Bullerwell, Asha, Dancy, Kaitlyn, DeVries, Trevor J, Shoveller, Anna K

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Inhibition of Bacterial Ice Nucleators Is Not an Intrinsic Property of Antifreeze Proteins von Schwidetzky, Ralph, Kunert, Anna T, Bonn, Mischa, Pöschl, Ulrich, Ramløv, Hans, DeVries, Arthur L, Fröhlich-Nowoisky, Janine, Meister, Konrad

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Measuring party positions in Europe: The Chapel Hill expert survey trend file, 1999–2010 von Bakker, Ryan, de Vries, Catherine, Edwards, Erica, Hooghe, Liesbet, Jolly, Seth, Marks, Gary, Polk, Jonathan, Rovny, Jan, Steenbergen, Marco, Vachudova, Milada Anna

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Quantitative Efficacy Classification of Ice Recrystallization Inhibition Agents von Budke, Carsten, Dreyer, Axel, Jaeger, Jasmin, Gimpel, Kerstin, Berkemeier, Thomas, Bonin, Anna S, Nagel, Lilly, Plattner, Carolin, DeVries, Arthur L, Sewald, Norbert, Koop, Thomas

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Carbon isotope records reveal precise timing of enhanced Southern Ocean upwelling during the last deglaciation von Siani, Giuseppe, Michel, Elisabeth, De Pol-Holz, Ricardo, DeVries, Tim, Lamy, Frank, Carel, Mélanie, Isguder, Gulay, Dewilde, Fabien, Lourantou, Anna

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Compromised axon initial segment integrity in EAE is preceded by microglial reactivity and contact von Clark, Kareem C., Josephson, Anna, Benusa, Savannah D., Hartley, Rebecca K., Baer, Matthew, Thummala, Suneel, Joslyn, Martha, Sword, Brooke A., Elford, Howard, Oh, Unsong, Dilsizoglu-Senol, Aysegul, Lubetzki, Catherine, Davenne, Marc, DeVries, George H., Dupree, Jeffrey L.

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