Biocatalysis in drug discovery and development von Fryszkowska, Anna, Devine, Paul N.

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Design of an in vitro biocatalytic cascade for the manufacture of islatravir von Huffman, Mark A, Fryszkowska, Anna, Alvizo, Oscar, Borra-Garske, Margie, Campos, Kevin R, Canada, Keith A, Devine, Paul N, Duan, Da, Forstater, Jacob H, Grosser, Shane T, Halsey, Holst M, Hughes, Gregory J, Jo, Junyong, Joyce, Leo A, Kolev, Joshua N, Liang, Jack, Maloney, Kevin M, Mann, Benjamin F, Marshall, Nicholas M, McLaughlin, Mark, Moore, Jeffrey C, Murphy, Grant S, Nawrat, Christopher C, Nazor, Jovana, Novick, Scott, Patel, Niki R, Rodriguez-Granillo, Agustina, Robaire, Sandra A, Sherer, Edward C, Truppo, Matthew D, Whittaker, Aaron M, Verma, Deeptak, Xiao, Li, Xu, Yingju, Yang, Hao

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An in vivo platform to select and evolve aggregation-resistant proteins von Ebo, Jessica S., Saunders, Janet C., Devine, Paul W. A., Gordon, Alice M., Warwick, Amy S., Schiffrin, Bob, Chin, Stacey E., England, Elizabeth, Button, James D., Lloyd, Christopher, Bond, Nicholas J., Ashcroft, Alison E., Radford, Sheena E., Lowe, David C., Brockwell, David J.

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Investigating the Structural Compaction of Biomolecules Upon Transition to the Gas-Phase Using ESI-TWIMS-MS von Devine, Paul W. A., Fisher, Henry C., Calabrese, Antonio N., Whelan, Fiona, Higazi, Daniel R., Potts, Jennifer R., Lowe, David C., Radford, Sheena E., Ashcroft, Alison E.

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Stochastic assembly of biomacromolecular complexes: impact and implications on charge interpretation in native mass spectrometry von Yin, Victor, Devine, Paul W. A, Saunders, Janet C, Barendregt, Arjan, Cusdin, Fiona, Ristani, Alexandra, Hines, Alistair, Shepherd, Sam, Dembek, Marcin, Dobson, Claire L, Snijder, Joost, Bond, Nicholas J, Heck, Albert J. R

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Cardiovascular risk in renal transplant recipients von Devine, Paul A., Courtney, Aisling E., Maxwell, Alexander P.

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Biocatalytic Asymmetric Synthesis of Chiral Amines from Ketones Applied to Sitagliptin Manufacture von Savile, Christopher K., Janey, Jacob M., Mundorff, Emily C., Moore, Jeffrey C., Tam, Sarena, Jarvis, William R., Colbeck, Jeffrey C., Krebber, Anke, Fleitz, Fred J., Brands, Jos, Devine, Paul N., Huisman, Gjalt W., Hughes, Gregory J.

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Interconversion of Unexpected Thiol States Affects the Stability, Structure, and Dynamics of Antibody Engineered for Site-Specific Conjugation von Orozco, Carolina T, Edgeworth, Matthew J, Devine, Paul W. A, Hines, Alistair R, Cornwell, Owen, Thompson, Christopher, Wang, Xiangyang, Phillips, Jonathan J, Ravn, Peter, Jackson, Sophie E, Bond, Nicholas J

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Skp is a multivalent chaperone of outer-membrane proteins von Schiffrin, Bob, Calabrese, Antonio N, Devine, Paul W A, Harris, Sarah A, Ashcroft, Alison E, Brockwell, David J, Radford, Sheena E

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Extending the application of biocatalysis to meet the challenges of drug development von Devine, Paul N., Howard, Roger M., Kumar, Rajesh, Thompson, Matthew P., Truppo, Matthew D., Turner, Nicholas J.

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Mass Activated Droplet Sorting (MADS) Enables High‐Throughput Screening of Enzymatic Reactions at Nanoliter Scale von Holland‐Moritz, Daniel A., Wismer, Michael K., Mann, Benjamin F., Farasat, Iman, Devine, Paul, Guetschow, Erik D., Mangion, Ian, Welch, Christopher J., Moore, Jeffrey C., Sun, Shuwen, Kennedy, Robert T.

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Advances in the Enzymatic Reduction of Ketones von Moore, Jeffrey C, Pollard, David J, Kosjek, Birgit, Devine, Paul N

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Engineering the surface properties of a human monoclonal antibody prevents self-association and rapid clearance in vivo von Dobson, Claire L., Devine, Paul W. A., Phillips, Jonathan J., Higazi, Daniel R., Lloyd, Christopher, Popovic, Bojana, Arnold, Joanne, Buchanan, Andrew, Lewis, Arthur, Goodman, Joanne, van der Walle, Christopher F., Thornton, Peter, Vinall, Lisa, Lowne, David, Aagaard, Anna, Olsson, Lise-Lotte, Ridderstad Wollberg, Anna, Welsh, Fraser, Karamanos, Theodoros K., Pashley, Clare L., Iadanza, Matthew G., Ranson, Neil A., Ashcroft, Alison E., Kippen, Alistair D., Vaughan, Tristan J., Radford, Sheena E., Lowe, David C.

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A kinase-cGAS cascade to synthesize a therapeutic STING activator von McIntosh, John A., Liu, Zhijian, Andresen, Brian M., Marzijarani, Nastaran Salehi, Moore, Jeffrey C., Marshall, Nicholas M., Borra-Garske, Margie, Obligacion, Jennifer V., Fier, Patrick S., Peng, Feng, Forstater, Jacob H., Winston, Matthew S., An, Chihui, Chang, Wonsuk, Lim, Jongwon, Huffman, Mark A., Miller, Steven P., Tsay, Fuh-Rong, Altman, Michael D., Lesburg, Charles A., Steinhuebel, Dietrich, Trotter, B. Wesley, Cumming, Jared N., Northrup, Alan, Bu, Xiaodong, Mann, Benjamin F., Biba, Mirlinda, Hiraga, Kaori, Murphy, Grant S., Kolev, Joshua N., Makarewicz, Amanda, Pan, Weilan, Farasat, Iman, Bade, Rachel S., Stone, Kevin, Duan, Da, Alvizo, Oscar, Adpressa, Donovan, Guetschow, Erik, Hoyt, Erik, Regalado, Erik L., Castro, Steve, Rivera, Nelo, Smith, Joseph P., Wang, Fengqiang, Crespo, Alejandro, Verma, Deeptak, Axnanda, Stephanus, Dance, Zachary E. X., Devine, Paul N., Tschaen, David, Canada, Keith A., Bulger, Paul G., Sherry, Benjamin D., Truppo, Matthew D., Ruck, Rebecca T., Campeau, Louis-Charles, Bennett, David Jonathan, Humphrey, Guy R., Campos, Kevin R., Maddess, Matthew L.

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Mechanistic insights into the rational design of masked antibodies von Orozco, Carolina T., Bersellini, Manuela, Irving, Lorraine M., Howard, Wesley W., Hargreaves, David, Devine, Paul W. A., Siouve, Elise, Browne, Gareth J., Bond, Nicholas J., Phillips, Jonathan J., Ravn, Peter, Jackson, Sophie E.

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Engineered CHO cells as a novel AAV production platform for gene therapy delivery von Nagy, Abdou, Chakrabarti, Lina, Kurasawa, James, Mulagapati, Sri Hari Raju, Devine, Paul, Therres, Jamy, Chen, Zhongying, Schmelzer, Albert E.

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Hemoprotein‐Catalyzed Cyclopropanation En Route to the Chiral Cyclopropanol Fragment of Grazoprevir von Kim, Taejin, Kassim, Amude M., Botejue, Ajit, Zhang, Chen, Forte, Jared, Rozzell, David, Huffman, Mark A., Devine, Paul N., McIntosh, John A.

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Antisense oligonucleotide activity in tumour cells is influenced by intracellular LBPA distribution and extracellular vesicle recycling von Kapustin, Alexander N., Davey, Paul, Longmire, David, Matthews, Carl, Linnane, Emily, Rustogi, Nitin, Stavrou, Maria, Devine, Paul W. A., Bond, Nicholas J., Hanson, Lyndsey, Sonzini, Silvia, Revenko, Alexey, MacLeod, A. Robert, Ross, Sarah, Chiarparin, Elisabetta, Puri, Sanyogitta

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Association of soluble ST2 with all-cause and cardiovascular mortality in renal transplant recipients: a single-centre cohort study von Devine, Paul A., Cardwell, Christopher, Maxwell, Alexander P.

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A chemoenzymatic strategy for site-selective functionalization of native peptides and proteins von Fryszkowska, Anna, An, Chihui, Alvizo, Oscar, Banerjee, Goutami, Canada, Keith A., Cao, Yang, DeMong, Duane, Devine, Paul N., Duan, Da, Elgart, David M., Farasat, Iman, Gauthier, Donald R., Guidry, Erin N., Jia, Xiujuan, Kong, Jongrock, Kruse, Nikki, Lexa, Katrina W., Makarov, Alexey A., Mann, Benjamin F., Milczek, Erika M., Mitchell, Vesna, Nazor, Jovana, Neri, Claudia, Orr, Robert K., Orth, Peter, Phillips, Eric M., Riggins, James N., Schafer, Wes A., Silverman, Steven M., Strulson, Christopher A., Subramanian, Nandhitha, Voladri, Rama, Yang, Hao, Yang, Jie, Yi, Xiang, Zhang, Xiyun, Zhong, Wendy

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