Accessing unexplored regions of sequence space in directed enzyme evolution via insertion/deletion mutagenesis von Emond, Stephane, Petek, Maya, Kay, Emily J., Heames, Brennen, Devenish, Sean R. A., Tokuriki, Nobuhiko, Hollfelder, Florian

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One in a Million: Flow Cytometric Sorting of Single Cell-Lysate Assays in Monodisperse Picolitre Double Emulsion Droplets for Directed Evolution von Zinchenko, Anastasia, Devenish, Sean R. A., Kintses, Balint, Colin, Pierre-Yves, Fischlechner, Martin, Hollfelder, Florian

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A Fully Unsupervised Compartment-on-Demand Platform for Precise Nanoliter Assays of Time-Dependent Steady-State Enzyme Kinetics and Inhibition von Gielen, Fabrice, van Vliet, Liisa, Koprowski, Bartosz T, Devenish, Sean R. A, Fischlechner, Martin, Edel, Joshua B, Niu, Xize, deMello, Andrew J, Hollfelder, Florian

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Serological fingerprints link antiviral activity of therapeutic antibodies to affinity and concentration von Fiedler, Sebastian, Devenish, Sean R. A., Morgunov, Alexey S., Ilsley, Alison, Ricci, Francesco, Emmenegger, Marc, Kosmoliaptsis, Vasilis, Theel, Elitza S., Mills, John R., Sholukh, Anton M., Aguzzi, Adriano, Iwasaki, Akiko, Lynn, Andrew K., Knowles, Tuomas P. J.

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Microfluidic droplets: new integrated workflows for biological experiments von Kintses, Balint, van Vliet, Liisa D, Devenish, Sean RA, Hollfelder, Florian

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Kinetic fingerprints differentiate the mechanisms of action of anti-Aβ antibodies von Linse, Sara, Scheidt, Tom, Bernfur, Katja, Vendruscolo, Michele, Dobson, Christopher M., Cohen, Samuel I. A., Sileikis, Eimantas, Lundqvist, Martin, Qian, Fang, O’Malley, Tiernan, Bussiere, Thierry, Weinreb, Paul H., Xu, Catherine K., Meisl, Georg, Devenish, Sean R. A., Knowles, Tuomas P. J., Hansson, Oskar

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A simple method to evaluate the biochemical compatibility of oil/surfactant mixtures for experiments in microdroplets von Kaltenbach, Miriam, Devenish, Sean R A, Hollfelder, Florian

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A single mutation in the core domain of the lac repressor reduces leakiness von Gatti-Lafranconi, Pietro, Dijkman, Willem P, Devenish, Sean R A, Hollfelder, Florian

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LC–MS and NMR characterization of the purple chromophore formed in the o-aminobenzaldehyde assay of dihydrodipicolinate synthase von Mitsakos, Voula, Devenish, Sean R.A., O’Donnell, Paul A., Gerrard, Juliet A., Hutton, Craig A.

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The current landscape in Alzheimer’s disease research and drug discovery von Devenish, Sean R.A.

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Microfluidic Antibody Affinity Profiling Reveals the Role of Memory Reactivation and Cross-Reactivity in the Defense Against SARS-CoV‑2 von Denninger, Viola, Xu, Catherine K, Meisl, Georg, Morgunov, Alexey S, Fiedler, Sebastian, Ilsley, Alison, Emmenegger, Marc, Malik, Anisa Y, Piziorska, Monika A, Schneider, Matthias M, Devenish, Sean R. A, Kosmoliaptsis, Vasilis, Aguzzi, Adriano, Fiegler, Heike, Knowles, Tuomas P. J

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NMR Studies Uncover Alternate Substrates for Dihydrodipicolinate Synthase and Suggest That Dihydrodipicolinate Reductase Is Also a Dehydratase von Devenish, Sean R. A, Blunt, John W, Gerrard, Juliet A

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Crystal structure and kinetic study of dihydrodipicolinate synthase from Mycobacterium tuberculosis von Kefala, Georgia, Evans, Genevieve L, Griffin, Michael D W, Devenish, Sean R A, Pearce, F Grant, Perugini, Matthew A, Gerrard, Juliet A, Weiss, Manfred S, Dobson, Renwick C J

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Microfluidic antibody affinity profiling of alloantibody-HLA interactions in human serum von Schneider, Matthias M., Scheidt, Tom, Priddey, Ashley J., Xu, Catherine K., Hu, Mengsha, Meisl, Georg, Devenish, Sean R.A., Dobson, Christopher M., Kosmoliaptsis, Vasilis, Knowles, Tuomas P.J.

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α‑Synuclein Oligomers Displace Monomeric α‑Synuclein from Lipid Membranes von Šneiderienė, Greta, Czekalska, Magdalena A., Xu, Catherine K., Jayaram, Akhila K., Krainer, Georg, Arter, William E., Peter, Quentin A. E., Castellana-Cruz, Marta, Saar, Kadi Liis, Levin, Aviad, Mueller, Thomas, Fiedler, Sebastian, Devenish, Sean R. A., Fiegler, Heike, Kumita, Janet R., Knowles, Tuomas P. J.

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FULL-MDS: Fluorescent Universal Lipid Labeling for Microfluidic Diffusional Sizing von Baron, Jasmin, Bauernhofer, Lena, Devenish, Sean R. A., Fiedler, Sebastian, Ilsley, Alison, Riedl, Sabrina, Zweytick, Dagmar, Glueck, David, Pessentheiner, Ariane, Durand, Grégory, Keller, Sandro

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How essential is the ‘essential’ active-site lysine in dihydrodipicolinate synthase? von Soares da Costa, Tatiana P., Muscroft-Taylor, Andrew C., Dobson, Renwick C.J., Devenish, Sean R.A., Jameson, Geoffrey B., Gerrard, Juliet A.

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Cloning and characterisation of dihydrodipicolinate synthase from the pathogen Neisseria meningitidis von Devenish, Sean R.A., Huisman, Frances H.A., Parker, Emily J., Hadfield, Andrea T., Gerrard, Juliet A.

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A tetrameric structure is not essential for activity in dihydrodipicolinate synthase (DHDPS) from Mycobacterium tuberculosis von Evans, Genevieve, Schuldt, Linda, Griffin, Michael D.W., Devenish, Sean R.A., Grant Pearce, F., Perugini, Matthew A., Dobson, Renwick C.J., Jameson, Geoffrey B., Weiss, Manfred S., Gerrard, Juliet A.

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Role of Arginine 138 in the Catalysis and Regulation of Escherichia coli Dihydrodipicolinate Synthase von Dobson, Renwick C. J, Devenish, Sean R. A, Turner, Leighton A, Clifford, Veronica R, Pearce, F. Grant, Jameson, Geoffrey B, Gerrard, Juliet A

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