Longitudinal profiling of the lung microbiome in the AERIS study demonstrates repeatability of bacterial and eosinophilic COPD exacerbations von Mayhew, David, Devos, Nathalie, Lambert, Christophe, Brown, James R, Clarke, Stuart C, Kim, Viktoriya L, Magid-Slav, Michal, Miller, Bruce E, Ostridge, Kristoffer K, Patel, Ruchi, Sathe, Ganesh, Simola, Daniel F, Staples, Karl J, Sung, Ruby, Tal-Singer, Ruth, Tuck, Andrew C, Van Horn, Stephanie, Weynants, Vincent, Williams, Nicholas P, Devaster, Jeanne-Marie, Wilkinson, Tom M A

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Molecular epidemiological study of nosocomial Enterobacter aerogenes isolates in a Belgian Hospital von JALALUDDIN, S, DEVASTER, J.-M, SCHEEN, R, GERARD, M, BUTZLER, J.-P

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Safety and immunogenicity of an AS03-adjuvanted A(H1N1)pmd09 vaccine administered simultaneously or sequentially with a seasonal trivalent vaccine in adults 61 years or older: Data... von Peeters, Mathieu, Regner, Stefan, Vaman, Tejaswini, Devaster, Jeanne-Marie, Rombo, Lars

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Do lean markers relate to exacerbation rate in chronic obstructive pulmonary disease? Preliminary results from AERIS study von Wojtas, M. M., Wootton, S., Barton, A., Kim, V., Ostridge, K., Williams, N., Aris, E., Peeters, M., Devaster, J. M., Bourne, S., Wilkinson, T.

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Impact and associations of eosinophilic inflammation in COPD: analysis of the AERIS cohort von Kim, Viktoriya L, Coombs, Ngaire A, Staples, Karl J, Ostridge, Kristoffer K, Williams, Nicholas P, Wootton, Stephen A, Devaster, Jeanne-Marie, Aris, Emmanuel, Clarke, Stuart C, Tuck, Andrew C, Bourne, Simon C, Wilkinson, Tom M A

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Interleukin-6: an early marker of bacterial infection in decompensated cirrhosis von Moine, Olivier Le, Devière, Jacques, Devaster, Jeanne-Marie, Crusiaux, Alain, Durand, François, Bernuau, Jacques, Goldman, Michel, Benhamou, Jean-Pierre

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Impact of radiologically stratified exacerbations: insights into pneumonia aetiology in COPD von Williams, Nicholas P, Ostridge, Kristoffer, Devaster, Jeanne-Marie, Kim, Viktoriya, Coombs, Ngaire A, Bourne, Simon, Clarke, Stuart C, Harden, Stephen, Abbas, Ausami, Aris, Emmanuel, Lambert, Christophe, Tuck, Andrew, Williams, Anthony, Wootton, Stephen, Staples, Karl J, Wilkinson, Tom M A

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Regulatory workshop on challenge strain development and GMP manufacture - a stakeholder meeting report von Corti, N, Chiu, C, Cox, RJ, Demont, C, Devaster, J-M, Engelhardt, OG, Gorringe, A, Hassan, K, Hoefnagel, M, Kamerling, I, Krut, O, Lane, C, Liebers, R, Luke, C, Van Molle, W, Morel, S, Neels, P, Roestenberg, M, Rubbrecht, M, Klaas Smits, W, Stoughton, D, Talaat, K, Vehreschild, MJGT, Wildfire, A, Meln, I, Olesen, OF

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Twelve year observation of primary and secondary antibiotic-resistant Helicobacter pylori strains in children von Bontems, Patrick, Devaster, Jeanne-Marie, Corvaglia, Luigi, Dezsöfi, Antal, van den Borre, Chantal, Goutier, Sylvianne, Butzler, Jean-Paul, Cadranel, Samy

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Role of gastric mucosal cytokines in the immunopathogenesis of Helicobacter pylori infection: new hypotheses but still few certitudes von Glupczynski, Youri, Devaster, Jeanne-Marie

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Trypsin activity : a new marker of acute alcoholic pancreatitis von LE MOINE, O, DEVASTER, J.-M, DEVIERE, J, THIRY, P, CREMER, M, OOMS, H.-A

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A47 NEW CONCEPTS IN COPD EXACERBATIONS: Lung Microbiome Analysis And Stochastic Modeling In The Aeris Study Identify Bacterial Profiles And Repetition Of Eosinophilic And Bacterial... von Mayhew, D, Devos, N, Lambert, C, Brown, J, Magid-Slav, M, Miller, B, Nozay, F, Patel, R, Sathe, G, Simola, D, Staples, K J, Sung, R, Tal-Singer, R, Van Horn, S, Weynants, V, Devaster, J-M, Wilkinson, T

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S37The persistence of eosinophilic inflammation in copd over time - aeris cohort von Kim, V L, Williams, N P, Ostridge, K K, Naghibi, M M, Coombs, NA, Devaster, J M, Aris, E, Clarke, S C, Tuck, A C, Wootton, SA, Bourne, S C, Staples, K J, Wilkinson, T M

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Drivers of year-to-year variation in exacerbation frequency of COPD: analysis of the AERIS cohort von Wilkinson, Tom M A, Aris, Emmanuel, Bourne, Simon C, Clarke, Stuart C, Peeters, Mathieu, Pascal, Thierry G, Taddei, Laura, Tuck, Andrew C, Kim, Viktoriya L, Ostridge, Kristoffer K, Staples, Karl J, Williams, Nicholas P, Williams, Anthony P, Wootton, Stephen A, Devaster, Jeanne-Marie

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B34 ALL THINGS MUST PASS: COPD EXACERBATIONS: The Role Of The Blood Neutrophil-Lymphocyte Ratio In Acute Exacerbations Of COPD von Williams, N, Ostridge, K, Kim, V, Barton, A, Wojtas, M, Harden, S, Aris, E, Peeters, M, Devaster, J-M, Bourne, S, Wilkinson, T

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D35 IT'S ALL TOO MUCH: COPD COMORBIDITIES: Incidental Lung Cancer And Pulmonary Nodules Identified By Research CT In A Population With Moderate To Very Severe COPD von Ostridge, K K, Kim, V, Williams, N, Barton, A, Harden, S, Aris, E, Peeters, M, Devaster, J-M, Bourne, S, Wilkinson, T

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C47 COPD: EXACERBATIONS: Respiratory Symptom Patterns Over One Year In Patients With COPD: Results From The Acute Exacerbation And Respiratory Infections (aeris) Study von Sung, R, Allinder, M, Aris, E, Bourne, S, Devaster, J-M, Kim, V, Leidy, N, Locantore, N, Mannino, F, Ostridge, K, Peeters, M, Tal-Singer, R, Welch, L, Weynants, V, Williams, N, Miller, B E, Wilkinson, T

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ACQUIRED RESISTANCE OF HELICOBACTER PYLORI STRAINS von Dezsöfi, A, Bontems, P, Devaster, J M, Cadranel, S

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Accuracy of serology and 13C-urea breath test for detection of Helicobacter pylori in children von CORVAGLIA, LUIGI, BONTEMS, PATRICK, DEVASTER, JEANNE-MARIE, HEIMANN, PIERRE, GLUPCZYNSKI, YOURI, KEPPENS, EDDY, CADRANEL, SAMY

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S37 The persistence of eosinophilic inflammation in copd over time – aeris cohort von Kim, VL, Williams, NP, Ostridge, KK, Naghibi, MM, Coombs, NA, Devaster, JM, Aris, E, Clarke, SC, Tuck, AC, Wootton, SA, Bourne, SC, Staples, KJ, Wilkinson, TM

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