The neuropathological diagnosis of Alzheimer's disease von DeTure, Michael A, Dickson, Dennis W

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Structure-based discovery of small molecules that disaggregate Alzheimer’s disease tissue derived tau fibrils in vitro von Seidler, Paul M., Murray, Kevin A., Boyer, David R., Ge, Peng, Sawaya, Michael R., Hu, Carolyn J., Cheng, Xinyi, Abskharon, Romany, Pan, Hope, DeTure, Michael A., Williams, Christopher K., Dickson, Dennis W., Vinters, Harry V., Eisenberg, David S.

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Posttranslational Modifications Mediate the Structural Diversity of Tauopathy Strains von Arakhamia, Tamta, Lee, Christina E., Carlomagno, Yari, Kumar, Mukesh, Duong, Duc M., Wesseling, Hendrik, Kundinger, Sean R., Wang, Kevin, Williams, Dewight, DeTure, Michael, Dickson, Dennis W., Cook, Casey N., Seyfried, Nicholas T., Petrucelli, Leonard, Steen, Judith A., Fitzpatrick, Anthony W.P.

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Three repeat isoforms of tau inhibit assembly of four repeat tau filaments von Adams, Stephanie J, DeTure, Michael A, McBride, Melinda, Dickson, Dennis W, Petrucelli, Leonard

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Structure-based inhibitors halt prion-like seeding by Alzheimer’s disease–and tauopathy–derived brain tissue samples von Seidler, Paul Matthew, Boyer, David R., Murray, Kevin A., Yang, Tianxiao P., Bentzel, Megan, Sawaya, Michael R., Rosenberg, Gregory, Cascio, Duilio, Williams, Christopher Kazu, Newell, Kathy L., Ghetti, Bernardino, DeTure, Michael A., Dickson, Dennis W., Vinters, Harry V., Eisenberg, David S.

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Homotypic fibrillization of TMEM106B across diverse neurodegenerative diseases von Chang, Andrew, Xiang, Xinyu, Wang, Jing, Lee, Carolyn, Arakhamia, Tamta, Simjanoska, Marija, Wang, Chi, Carlomagno, Yari, Zhang, Guoan, Dhingra, Shikhar, Thierry, Manon, Perneel, Jolien, Heeman, Bavo, Forgrave, Lauren M., DeTure, Michael, DeMarco, Mari L., Cook, Casey N., Rademakers, Rosa, Dickson, Dennis W., Petrucelli, Leonard, Stowell, Michael H.B., Mackenzie, Ian R.A., Fitzpatrick, Anthony W.P.

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Acetylation of the KXGS motifs in tau is a critical determinant in modulation of tau aggregation and clearance von Cook, Casey, Carlomagno, Yari, Gendron, Tania F, Dunmore, Judy, Scheffel, Kristyn, Stetler, Caroline, Davis, Mary, Dickson, Dennis, Jarpe, Matthew, DeTure, Michael, Petrucelli, Leonard

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Comprehensive characterization of human brain‐derived extracellular vesicles using multiple isolation methods: Implications for diagnostic and therapeutic applications von Zhang, Zhengrong, Yu, Kaiwen, You, Yang, Jiang, Peizhou, Wu, Zhiping, DeTure, Michael A., Dickson, Dennis W., Ikezu, Seiko, Peng, Junmin, Ikezu, Tsuneya

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Microglial Homeostasis Requires Balanced CSF-1/CSF-2 Receptor Signaling von Chitu, Violeta, Biundo, Fabrizio, Shlager, Gabriel G.L., Park, Eun S., Wang, Ping, Gulinello, Maria E., Gokhan, Şölen, Ketchum, Harmony C., Saha, Kusumika, DeTure, Michael A., Dickson, Dennis W., Wszolek, Zbignew K., Zheng, Deyou, Croxford, Andrew L., Becher, Burkhard, Sun, Daqian, Mehler, Mark F., Stanley, E. Richard

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Tau seeds catalyze fibril-type structures from GFP tau biosensor cells von Wang, Jinliang, Williams, Christopher K., DeTure, Michael A., Magaki, Shino D., Dickson, Dennis W., Vinters, Harry V., Seidler, Paul M.

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Distinct brain transcriptome profiles in C9orf72-associated and sporadic ALS von Prudencio, Mercedes, Belzil, Veronique V, Batra, Ranjan, Ross, Christian A, Gendron, Tania F, Pregent, Luc J, Murray, Melissa E, Overstreet, Karen K, Piazza-Johnston, Amelia E, Desaro, Pamela, Bieniek, Kevin F, DeTure, Michael, Lee, Wing C, Biendarra, Sherri M, Davis, Mary D, Baker, Matthew C, Perkerson, Ralph B, van Blitterswijk, Marka, Stetler, Caroline T, Rademakers, Rosa, Link, Christopher D, Dickson, Dennis W, Boylan, Kevin B, Li, Hu, Petrucelli, Leonard

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α-Synuclein filaments from transgenic mouse and human synucleinopathy-containing brains are major seed-competent species von Morgan, Sophie A., Lavenir, Isabelle, Fan, Juan, Masuda-Suzukake, Masami, Passarella, Daniela, DeTure, Michael A., Dickson, Dennis W., Ghetti, Bernardino, Goedert, Michel

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Aggregation-prone c9FTD/ALS poly(GA) RAN-translated proteins cause neurotoxicity by inducing ER stress von Zhang, Yong-Jie, Jansen-West, Karen, Xu, Ya-Fei, Gendron, Tania F., Bieniek, Kevin F., Lin, Wen-Lang, Sasaguri, Hiroki, Caulfield, Thomas, Hubbard, Jaime, Daughrity, Lillian, Chew, Jeannie, Belzil, Veronique V., Prudencio, Mercedes, Stankowski, Jeannette N., Castanedes-Casey, Monica, Whitelaw, Ena, Ash, Peter E. A., DeTure, Michael, Rademakers, Rosa, Boylan, Kevin B., Dickson, Dennis W., Petrucelli, Leonard

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APOE4 exacerbates α-synuclein seeding activity and contributes to neurotoxicity in Alzheimer’s disease with Lewy body pathology von Jin, Yunjung, Li, Fuyao, Sonoustoun, Berkiye, Kondru, Naveen Chandra, Martens, Yuka A., Qiao, Wenhui, Heckman, Michael G., Ikezu, Tadafumi C., Li, Zonghua, Burgess, Jeremy D., Amerna, Danilyn, O’Leary, Justin, DeTure, Michael A., Zhao, Jing, McLean, Pamela J., Dickson, Dennis W., Ross, Owen A., Bu, Guojun, Zhao, Na

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Association of MAPT Subhaplotypes With Risk of Progressive Supranuclear Palsy and Severity of Tau Pathology von Heckman, Michael G, Brennan, Rebecca R, Labbé, Catherine, Soto, Alexandra I, Koga, Shunsuke, DeTure, Michael A, Murray, Melissa E, Petersen, Ronald C, Boeve, Bradley F, van Gerpen, Jay A, Uitti, Ryan J, Wszolek, Zbigniew K, Rademakers, Rosa, Dickson, Dennis W, Ross, Owen A

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Elevated granulocyte colony stimulating factor (CSF) causes cerebellar deficits and anxiety in a model of CSF‐1 receptor related leukodystrophy von Biundo, Fabrizio, Chitu, Violeta, Tindi, Jaafar, Burghardt, Nesha S., Shlager, Gabriel G. L., Ketchum, Harmony C., DeTure, Michael A., Dickson, Dennis W., Wszolek, Zbignew K., Khodakhah, Kamran, Stanley, E. Richard

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Transcriptomic analysis to identify genes associated with selective hippocampal vulnerability in Alzheimer’s disease von Crist, Angela M., Hinkle, Kelly M., Wang, Xue, Moloney, Christina M., Matchett, Billie J., Labuzan, Sydney A., Frankenhauser, Isabelle, Azu, Nkem O., Liesinger, Amanda M., Lesser, Elizabeth R., Serie, Daniel J., Quicksall, Zachary S., Patel, Tulsi A., Carnwath, Troy P., DeTure, Michael, Tang, Xiaojia, Petersen, Ronald C., Duara, Ranjan, Graff-Radford, Neill R., Allen, Mariet, Carrasquillo, Minerva M., Li, Hu, Ross, Owen A., Ertekin-Taner, Nilüfer, Dickson, Dennis W., Asmann, Yan W., Carter, Rickey E., Murray, Melissa E.

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Crystal structure of a conformational antibody that binds tau oligomers and inhibits pathological seeding by extracts from donors with Alzheimer's disease von Abskharon, Romany, Seidler, Paul M., Sawaya, Michael R., Cascio, Duilio, Yang, Tianxiao P., Philipp, Stephan, Williams, Christopher Kazu, Newell, Kathy L., Ghetti, Bernardino, DeTure, Michael A., Dickson, Dennis W., Vinters, Harry V., Felgner, Philip L., Nakajima, Rie, Glabe, Charles G., Eisenberg, David S.

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Impact of sex and APOE4 on cerebral amyloid angiopathy in Alzheimer’s disease von Shinohara, Mitsuru, Murray, Melissa E., Frank, Ryan D., Shinohara, Motoko, DeTure, Michael, Yamazaki, Yu, Tachibana, Masaya, Atagi, Yuka, Davis, Mary D., Liu, Chia-Chen, Zhao, Na, Painter, Meghan M., Petersen, Ronald C., Fryer, John D., Crook, Julia E., Dickson, Dennis W., Bu, Guojun, Kanekiyo, Takahisa

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APOE2 Exacerbates TDP‐43 Related Toxicity in the Absence of Alzheimer Pathology von Meneses, Axel D., Koga, Shunsuke, Li, Zonghua, O'Leary, Justin, Li, Fuyao, Chen, Kai, Murakami, Aya, Qiao, Wenhui, Kurti, Aishe, Heckman, Michael G., White, Launia, Xie, Manling, Chen, Yixing, Finch, Nicole A., Lim, Melina J., Delenclos, Marion, DeTure, Michael A., Linares, Cynthia, Martin, Nicholas B., Ikezu, Tadafumi C., Blitterswijk, Marka M., Wu, Long‐Jun, McLean, Pamela J., Rademakers, Rosa, Ross, Owen A., Dickson, Dennis W., Bu, Guojun, Zhao, Na

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