Aberrant splicing of HTT generates the pathogenic exon 1 protein in Huntington disease von Sathasivam, Kirupa, Neueder, Andreas, Gipson, Theresa A., Landles, Christian, Benjamin, Agnesska C., Bondulich, Marie K., Smith, Donna L., Faull, Richard L. M., Roos, Raymund A. C., Howland, David, Detloff, Peter J., Housman, David E., Bates, Gillian P.

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Estrogen-related receptor gamma is a regulator of mitochondrial, autophagy, and immediate-early gene programs in spiny projection neurons: Relevance for transcriptional changes in... von Fox, Stephanie N., Savage, Cody H., Amireddy, Narcy R., McMeekin, Laura J., Crossman, David K., Detloff, Peter J., Gray, Michelle, Cowell, Rita M.

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Early white matter abnormalities, progressive brain pathology and motor deficits in a novel knock-in mouse model of Huntington's disease von Jin, Jing, Peng, Qi, Hou, Zhipeng, Jiang, Mali, Wang, Xin, Langseth, Abraham J, Tao, Michael, Barker, Peter B, Mori, Susumu, Bergles, Dwight E, Ross, Christopher A, Detloff, Peter J, Zhang, Jiangyang, Duan, Wenzhen

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Intraflagellar transport is essential for endochondral bone formation von Haycraft, Courtney J, Zhang, Qihong, Song, Buer, Jackson, Walker S, Detloff, Peter J, Serra, Rosa, Yoder, Bradley K

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Rodent genetic models of Huntington disease von Heng, Mary Y, Detloff, Peter J, Albin, Roger L

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DNA instability in postmitotic neurons von Gonitel, Roman, Moffitt, Hilary, Sathasivam, Kirupa, Woodman, Ben, Detloff, Peter J, Faull, Richard L.M, Bates, Gillian P

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Early autophagic response in a novel knock-in model of Huntington disease von Heng, Mary Y., Duong, Duy K., Albin, Roger L., Tallaksen-Greene, Sara J., Hunter, Jesse M., Lesort, Mathieu J., Osmand, Alex, Paulson, Henry L., Detloff, Peter J.

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Early alterations of autophagy in Huntington disease-like mice von Heng, Mary Y., Detloff, Peter J., Paulson, Henry L., Albin, Roger L.

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Progression of behavioural despair in R6/2 and Hdh knock-in mouse models recapitulates depression in Huntington's disease von Ciamei, Alessandro, Detloff, Peter J., Morton, A. Jennifer

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Sex-dependent behavioral impairments in the HdhQ350/+ mouse line von Cao, Jessica K., Detloff, Peter J., Gardner, Richard G., Stella, Nephi

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Ectopically Expressed CAG Repeats Cause Intranuclear Inclusions and a Progressive Late Onset Neurological Phenotype in the Mouse von Ordway, Jared M, Tallaksen-Greene, Sara, Gutekunst, Claire-Anne, Bernstein, Eve M, Cearley, Jamie A, Wiener, Howard W, Dure, Leon S, Lindsey, Russell, Hersch, Steven M, Jope, Richard S, Albin, Roger.L, Detloff, Peter J

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Mutant huntingtin directly increases susceptibility of mitochondria to the calcium-induced permeability transition and cytochrome c release von Choo, Yeun Su, Johnson, Gail V.W., MacDonald, Marcy, Detloff, Peter J., Lesort, Mathieu

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Longitudinal Evaluation of the Hdh(CAG)150 Knock-In Murine Model of Huntington's Disease von Heng, Mary Y, Tallaksen-Greene, Sara J, Detloff, Peter J, Albin, Roger L

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Cell-Specific Deletion of PGC-1α from Medium Spiny Neurons Causes Transcriptional Alterations and Age-Related Motor Impairment von McMeekin, Laura J, Li, Ye, Fox, Stephanie N, Rowe, Glenn C, Crossman, David K, Day, Jeremy J, Li, Yuqing, Detloff, Peter J, Cowell, Rita M

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Dramatic tissue-specific mutation length increases are an early molecular event in Huntington disease pathogenesis von Kennedy, Laura, Evans, Elizabeth, Chen, Chiung-Mei, Craven, Lyndsey, Detloff, Peter J., Ennis, Margaret, Shelbourne, Peggy F.

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In Vivo Evidence for NMDA Receptor-Mediated Excitotoxicity in a Murine Genetic Model of Huntington Disease von Heng, Mary Y, Detloff, Peter J, Wang, Phillip L, Tsien, Joe Z, Albin, Roger L

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Characterisation of progressive motor deficits in whisker movements in R6/2, Q175 and Hdh knock-in mouse models of Huntington’s disease von Garland, Huw, Wood, Nigel I., Skillings, Elizabeth A., Detloff, Peter J., Morton, A. Jennifer, Grant, Robyn A.

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Allelic series of Huntington's disease knock-in mice reveals expression discorrelates von Kumar, Ashish, Zhang, Jennifer, Tallaksen-Greene, Sara, Crowley, Michael R, Crossman, David K, Morton, A Jennifer, Van Groen, Thomas, Kadish, Inga, Albin, Roger L, Lesort, Mathieu, Detloff, Peter J

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Neurological abnormalities in a knock-in mouse model of Huntington's disease von LIN, Chin-Hsing, TALLAKSEN-GREENE, Sara, CHIEN, Wei-Ming, CEARLEY, Jamie A, JACKSON, Walker S, CROUSE, Andrew B, REN, Songrong, LI, Xiao-Jiang, ALBIN, Roger L, DETLOFF, Peter J

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Tissue transglutaminase overexpression does not modify the disease phenotype of the R6/2 mouse model of Huntington's disease von Kumar, Ashish, Kneynsberg, Andrew, Tucholski, Janusz, Perry, Giselle, van Groen, Thomas, Detloff, Peter J., Lesort, Mathieu

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