Multiple APOBEC3 Restriction Factors for HIV-1 and One Vif to Rule Them All von Desimmie, Belete A., Delviks-Frankenberrry, Krista A., Burdick, Ryan C., Qi, DongFei, Izumi, Taisuke, Pathak, Vinay K.

Volltext

Rational design of small-molecule inhibitors of the LEDGF/p75-integrase interaction and HIV replication von Debyser, Zeger, Christ, Frauke, Voet, Arnout, Marchand, Arnaud, Nicolet, Stefan, Desimmie, Belete A, Marchand, Damien, Bardiot, Dorothée, Van der Veken, Nam Joo, Van Remoortel, Barbara, Strelkov, Sergei V, De Maeyer, Marc, Chaltin, Patrick

Volltext

Small-Molecule Inhibitors of the LEDGF/p75 Binding Site of Integrase Block HIV Replication and Modulate Integrase Multimerization von CHRIST, Frauke, SHAW, Stephen, PICKFORD, Chris, DEMEULEMEESTER, Jonas, DESIMMIE, Belete A, MARCHAND, Arnaud, BUTLER, Scott, SMETS, Wim, CHALTIN, Patrick, WESTBY, Mike, DEBYSER, Zeger

Volltext

Insights into SARS-CoV-2 Persistence and Its Relevance von Desimmie, Belete A., Raru, Yonas Y., Awadh, Hesham M., He, Peimei, Teka, Samson, Willenburg, Kara S.

Volltext

Insights into DNA substrate selection by APOBEC3G from structural, biochemical, and functional studies von Ziegler, Samantha J, Liu, Chang, Landau, Mark, Buzovetsky, Olga, Desimmie, Belete A, Zhao, Qi, Sasaki, Tomoaki, Burdick, Ryan C, Pathak, Vinay K, Anderson, Karen S, Xiong, Yong

Volltext

Structural Insights into APOBEC3-Mediated Lentiviral Restriction von Delviks-Frankenberry, Krista A., Desimmie, Belete A., Pathak, Vinay K.

Volltext

Insights into Adherence among a Cohort of Adolescents Aged 12-20 Years in South Africa: Reported Barriers to Antiretroviral Treatment von Technau, Karl, Malete, Given, Jamieson, Lise, Govindasamy, Darshini, Evans, Denise, Fox, Matthew P., Maskew, Mhairi, Mongwenyana, Constance

Volltext

Cluster-Randomized Controlled Study of SMS Text Messages for Prevention of Mother-to-Child Transmission of HIV in Rural Kenya von Machekano, Rhoderick, Muthama, David, Simiyu, Rogers, McOdida, Peter, Matu, Lucy, Kose, Judith, Sirengo, Martin, Ong’ech, John, Kassaye, Seble, Syengo, Titus

Volltext

Visceral leishmaniasis relapse in HIV patients--a role for myeloid-derived suppressor cells? von Van den Bergh, Rafael, Van Ginderachter, Jo A, Schouppe, Elio, Desimmie, Belete A, Hailu, Asrat, De Baetselier, Patrick, van Griensven, Johan

Volltext

Structural basis of antagonism of human APOBEC3F by HIV-1 Vif von Hu, Yingxia, Desimmie, Belete A., Nguyen, Henry C., Ziegler, Samantha J., Cheng, Tat Cheung, Chen, John, Wang, Jia, Wang, Hongwei, Zhang, Kai, Pathak, Vinay K., Xiong, Yong

Volltext

Phage Display-Directed Discovery of LEDGF/p75 Binding Cyclic Peptide Inhibitors of HIV Replication von Desimmie, Belete A., Humbert, Michael, Lescrinier, Eveline, Hendrix, Jelle, Vets, Sofie, Gijsbers, Rik, Ruprecht, Ruth M., Dietrich, Ursula, Debyser, Zeger, Christ, Frauke

Volltext

Phage Display-directed Discovery of LEDGF/p75 Binding Cyclic Peptide Inhibitors of HIV Replication von Desimmie, Belete A, Humbert, Michael, Lescrinier, Eveline, Hendrix, Jelle, Vets, Sofie, Gijsbers, Rik, Ruprecht, Ruth M, Dietrich, Ursula, Debyser, Zeger, Christ, Frauke

Volltext

APOBEC3 proteins can copackage and comutate HIV-1 genomes von Desimmie, Belete A, Burdick, Ryan C, Izumi, Taisuke, Doi, Hibiki, Shao, Wei, Alvord, W Gregory, Sato, Kei, Koyanagi, Yoshio, Jones, Sara, Wilson, Eleanor, Hill, Shawn, Maldarelli, Frank, Hu, Wei-Shau, Pathak, Vinay K

Volltext

The roles of five conserved lentiviral RNA structures in HIV-1 replication von Liu, Yang, Chen, Jianbo, Nikolaitchik, Olga A., Desimmie, Belete A., Busan, Steven, Pathak, Vinay K., Weeks, Kevin M., Hu, Wei-Shau

Volltext

Identification of a tripartite interaction between the N-terminus of HIV-1 Vif and CBFβ that is critical for Vif function von Desimmie, Belete A, Smith, Jessica L, Matsuo, Hiroshi, Hu, Wei-Shau, Pathak, Vinay K

Volltext

2‑Hydroxyisoquinoline-1,3(2H,4H)‑diones (HIDs), Novel Inhibitors of HIV Integrase with a High Barrier to Resistance von Desimmie, Belete A, Demeulemeester, Jonas, Suchaud, Virginie, Taltynov, Oliver, Billamboz, Muriel, Lion, Cedric, Bailly, Fabrice, Strelkov, Sergei V, Debyser, Zeger, Cotelle, Philippe, Christ, Frauke

Volltext

Cellular Cofactors of Lentiviral Integrase: From Target Validation to Drug Discovery von Taltynov, Oliver, Desimmie, Belete A., Demeulemeester, Jonas, Christ, Frauke, Debyser, Zeger

Volltext

Validation of host factors of HIV integration as novel drug targets for anti-HIV therapy von Debyser, Zeger, Desimmie, Belete A, Taltynov, Oliver, Demeulemeester, Jonas, Christ, Frauke

Volltext

Rational design of LEDGINs as first allosteric integrase inhibitors for the treatment of HIV infection von Desimmie, Belete A., Demeulemeester, Jonas, Christ, Frauke, Debyser, Zeger

Volltext

HIV-1 IN/Pol recruits LEDGF/p75 into viral particles von Desimmie, Belete Ayele, Weydert, Caroline, Schrijvers, Rik, Vets, Sofie, Demeulemeester, Jonas, Proost, Paul, Paron, Igor, De Rijck, Jan, Mast, Jan, Bannert, Norbert, Gijsbers, Rik, Christ, Frauke, Debyser, Zeger

Volltext