Genetic And Morphological Evaluation (GAME) score for patients with colorectal liver metastases von Margonis, G. A., Sasaki, K., Gholami, S., Kim, Y., Andreatos, N., Rezaee, N., Deshwar, A., Buettner, S., Allen, P. J., Kingham, T. P., Pawlik, T. M., He, J., Cameron, J. L., Jarnagin, W. R., Wolfgang, C. L., D'Angelica, M. I., Weiss, M. J.

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Characterizing genetic intra-tumor heterogeneity across 2,658 human cancer genomes von Dentro, Stefan C., Leshchiner, Ignaty, Haase, Kerstin, Wintersinger, Jeff, Deshwar, Amit G., Yu, Kaixian, Rubanova, Yulia, Macintyre, Geoff, Demeulemeester, Jonas, Vázquez-García, Ignacio, Kleinheinz, Kortine, Livitz, Dimitri G., Malikic, Salem, Donmez, Nilgun, Sengupta, Subhajit, Anur, Pavana, Jolly, Clemency, Rosebrock, Daniel, Schumacher, Steven E., Fittall, Matthew, Drews, Ruben M., Yao, Xiaotong, Lee, Juhee, Schlesner, Matthias, Zhu, Hongtu, Adams, David J., McGranahan, Nicholas, Swanton, Charles, Getz, Gad, Boutros, Paul C., Imielinski, Marcin, Beroukhim, Rameen, Sahinalp, S. Cenk, Ji, Yuan, Peifer, Martin, Martincorena, Inigo, Markowetz, Florian, Mustonen, Ville, Yuan, Ke, Gerstung, Moritz, Spellman, Paul T., Wang, Wenyi, Wedge, David C., Dentro, Stefan C., Leshchiner, Ignaty, Gerstung, Moritz, Jolly, Clemency, Haase, Kerstin, Tarabichi, Maxime, Wintersinger, Jeff, Deshwar, Amit G., Yu, Kaixian, Rubanova, Yulia, Macintyre, Geoff, Demeulemeester, Jonas, Anur, Pavana, Beroukhim, Rameen, Boutros, Paul C., Bowtell, David D., Cao, Shaolong, Cmero, Marek, Cun, Yupeng, Dawson, Kevin J., Donmez, Nilgun, Drews, Ruben M., Eils, Roland, Fan, Yu, Fittall, Matthew, Getz, Gad, Ha, Gavin, Imielinski, Marcin, Ji, Yuan, Kleinheinz, Kortine, Lee, Juhee, Lee-Six, Henry, Livitz, Dimitri G., Malikic, Salem, Markowetz, Florian, Martincorena, Inigo, Mustonen, Ville, Oesper, Layla, Peifer, Martin, Peto, Myron, Raphael, Benjamin J., Rosebrock, Daniel, Salcedo, Adriana, Schumacher, Steven E., Sengupta, Subhajit, Shi, Ruian, Spiro, Oliver, Vázquez-García, Ignacio, Vembu, Shankar, Wheeler, David A., Yao, Xiaotong, Yuan, Ke, Wang, Wenyi, Morris, Quaid D., Spellman, Paul T., Wedge, David C., Van Loo, Peter

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33 PAN-cancer whole genome sequencing reveals patterns of subclonal mutations, signature changes and selection von Haase, K, Dentro, S, Leshchiner, I, Wintersinger, J, Deshwar, A, Tarabichi, M, Morris, Q, Wedge, D, Loo, P Van

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Neutral tumor evolution? von Tarabichi, Maxime, Martincorena, Iñigo, Gerstung, Moritz, Leroi, Armand M., Markowetz, Florian, Spellman, Paul T., Morris, Quaid D., Lingjærde, Ole Christian, Wedge, David C., Van Loo, Peter

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Crowd-sourced benchmarking of single-sample tumor subclonal reconstruction von Salcedo, Adriana, Tarabichi, Maxime, Buchanan, Alex, Espiritu, Shadrielle M G, Zhang, Hongjiu, Zhu, Kaiyi, Ou Yang, Tai-Hsien, Leshchiner, Ignaty, Anastassiou, Dimitris, Guan, Yuanfang, Jang, Gun Ho, Mootor, Mohammed F E, Haase, Kerstin, Deshwar, Amit G, Zou, William, Umar, Imaad, Dentro, Stefan, Wintersinger, Jeff A, Chiotti, Kami, Demeulemeester, Jonas, Jolly, Clemency, Sycza, Lesia, Ko, Minjeong, Wedge, David C, Morris, Quaid D, Ellrott, Kyle, Van Loo, Peter, Boutros, Paul C

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Reconstructing evolutionary trajectories of mutation signature activities in cancer using TrackSig von Rubanova, Y, Shi, R, Harrigan, CF, Li, R, Wintersinger, J, Sahin, N, Deshwar, A, PCAWG Evolution and Heterogeneity Working Group, Morris, Q, PCAWG Consortium

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The evolutionary history of 2,658 cancers von Gerstung, M, Jolly, C, Leshchiner, I, Dentro, SC, Gonzalez, S, Rosebrock, D, Mitchell, TJ, Rubanova, Y, Anur, P, Yu, K, Tarabichi, M, Deshwar, A, Wintersinger, J, Kleinheinz, K, Vázquez-García, I, Haase, K, Jerman, L, Sengupta, S, Macintyre, G, Malikic, S, Donmez, N, Livitz, DG, Cmero, M, Demeulemeester, J, Schumacher, S, Fan, Y, Yao, X, Lee, J, Schlesner, M, Boutros, PC, Bowtell, DD, Zhu, H, Getz, G, Imielinski, M, Beroukhim, R, Sahinalp, SC, Ji, Y, Peifer, M, Markowetz, F, Mustonen, V, Yuan, K, Wang, W, Morris, QD, PCAWG Evolution & Heterogeneity Working Group, Spellman, PT, Wedge, DC, Van Loo, P, PCAWG Consortium

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Characterizing genetic intra-tumor heterogeneity across 2,658 human cancer genomes von Dentro, SC, Leshchiner, I, Haase, K, Tarabichi, M, Wintersinger, J, Deshwar, AG, Yu, K, Rubanova, Y, Macintyre, G, Demeulemeester, J, Vázquez-García, I, Kleinheinz, K, Livitz, DG, Malikic, S, Donmez, N, Sengupta, S, Anur, P, Jolly, C, Cmero, M, Rosebrock, D, Schumacher, SE, Fan, Y, Fittall, M, Drews, RM, Yao, X, Watkins, TBK, Lee, J, Schlesner, M, Zhu, H, Adams, DJ, McGranahan, N, Swanton, C, Getz, G, Boutros, PC, Imielinski, M, Beroukhim, R, Sahinalp, SC, Ji, Y, Peifer, M, Martincorena, I, Markowetz, F, Mustonen, V, Yuan, K, Gerstung, M, Spellman, PT, Wang, W, Morris, QD, Wedge, DC, Van Loo, P, PCAWG Evolution and Heterogeneity Working Group and the PCAWG Co

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Inferring clonal evolution of tumors from single nucleotide somatic mutations von Jiao, Wei, Vembu, Shankar, Deshwar, Amit G, Stein, Lincoln, Morris, Quaid

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PhyloWGS: reconstructing subclonal composition and evolution from whole-genome sequencing of tumors von Deshwar, Amit G, Vembu, Shankar, Yung, Christina K, Jang, Gun Ho, Stein, Lincoln, Morris, Quaid

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A practical guide to cancer subclonal reconstruction from DNA sequencing von Tarabichi, Maxime, Salcedo, Adriana, Deshwar, Amit G., Ni Leathlobhair, Máire, Wintersinger, Jeff, Wedge, David C., Van Loo, Peter, Morris, Quaid D., Boutros, Paul C.

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Loss of Mtm1 causes cholestatic liver disease in a model of X-linked myotubular myopathy von Karolczak, Sophie, Deshwar, Ashish R, Aristegui, Evangelina, Kamath, Binita M, Lawlor, Michael W, Andreoletti, Gaia, Volpatti, Jonathan R, Ellis, Jillian L, Yin, Chunyue, Dowling, James J

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Correction of a splicing defect in a mouse model of congenital muscular dystrophy type 1A using a homology-directed-repair-independent mechanism von Kemaladewi, Dwi U, Maino, Eleonora, Hyatt, Elzbieta, Hou, Huayun, Ding, Maylynn, Place, Kara M, Zhu, Xinyi, Bassi, Prabhpreet, Baghestani, Zahra, Deshwar, Amit G, Merico, Daniele, Xiong, Hui Y, Frey, Brendan J, Wilson, Michael D, Ivakine, Evgueni A, Cohn, Ronald D

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COSSMO: predicting competitive alternative splice site selection using deep learning von Bretschneider, Hannes, Gandhi, Shreshth, Deshwar, Amit G, Zuberi, Khalid, Frey, Brendan J

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Hey2 regulates the size of the cardiac progenitor pool during vertebrate heart development von Gibb, Natalie, Lazic, Savo, Yuan, Xuefei, Deshwar, Ashish R, Leslie, Meaghan, Wilson, Michael D, Scott, Ian C

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A homozygous pathogenic variant in SHROOM3 associated with anencephaly and cleft lip and palate von Deshwar, Ashish R., Martin, Nicole, Shannon, Patrick, Chitayat, David

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Transcriptome-Wide Off-Target Effects of Steric-Blocking Oligonucleotides von Holgersen, Erle M., Gandhi, Shreshth, Zhou, Yongchao, Kim, Jinkuk, Vaz, Brandon, Bogojeski, Jovanka, Bugno, Magdalena, Shalev, Zvi, Cheung-Ong, Kahlin, Goncalves, Joao, O'Hara, Matthew, Kron, Ken, Verby, Marta, Sun, Mark, Kakaradov, Boyko, Delong, Andrew, Merico, Daniele, Deshwar, Amit G.

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PLIDA: cross-platform gene expression normalization using perturbed topic models von Deshwar, Amit G, Morris, Quaid

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Trio RNA sequencing in a cohort of medically complex children von Deshwar, Ashish R., Yuki, Kyoko E., Hou, Huayun, Liang, Yijing, Khan, Tayyaba, Celik, Alper, Ramani, Arun, Mendoza-Londono, Roberto, Marshall, Christian R., Brudno, Michael, Shlien, Adam, Meyn, M. Stephen, Hayeems, Robin Z., McKinlay, Brandon J., Klentrou, Panagiota, Wilson, Michael D., Kyriakopoulou, Lianna, Costain, Gregory, Dowling, James J.

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The Apelin receptor enhances Nodal/TGFβ signaling to ensure proper cardiac development von Deshwar, Ashish R, Chng, Serene C, Ho, Lena, Reversade, Bruno, Scott, Ian C

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