Lipid-Associated Macrophages Control Metabolic Homeostasis in a Trem2-Dependent Manner von Jaitin, Diego Adhemar, Adlung, Lorenz, Thaiss, Christoph A., Weiner, Assaf, Li, Baoguo, Descamps, Hélène, Lundgren, Patrick, Bleriot, Camille, Liu, Zhaoyuan, Deczkowska, Aleksandra, Keren-Shaul, Hadas, David, Eyal, Zmora, Niv, Eldar, Shai Meron, Lubezky, Nir, Shibolet, Oren, Hill, David A., Lazar, Mitchell A., Colonna, Marco, Ginhoux, Florent, Shapiro, Hagit, Elinav, Eran, Amit, Ido

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The path toward using microbial metabolites as therapies von Descamps, Hélène C., Herrmann, Beatrice, Wiredu, Daphne, Thaiss, Christoph A.

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Extracellular Vesicles Containing IL-4 Modulate Neuroinflammation in a Mouse Model of Multiple Sclerosis von Casella, Giacomo, Colombo, Federico, Finardi, Annamaria, Descamps, Hélène, Ill-Raga, Gerard, Spinelli, Antonello, Podini, Paola, Bastoni, Mattia, Martino, Gianvito, Muzio, Luca, Furlan, Roberto

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NAD+ flux is maintained in aged mice despite lower tissue concentrations von McReynolds, Melanie R., Chellappa, Karthikeyani, Chiles, Eric, Jankowski, Connor, Shen, Yihui, Chen, Li, Descamps, Hélène C., Mukherjee, Sarmistha, Bhat, Yashaswini R., Lingala, Siddharth R., Chu, Qingwei, Botolin, Paul, Hayat, Faisal, Doke, Tomohito, Susztak, Katalin, Thaiss, Christoph A., Lu, Wenyun, Migaud, Marie E., Su, Xiaoyang, Rabinowitz, Joshua D., Baur, Joseph A.

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Astrocyte TrkB promotes brain injury and edema formation in ischemic stroke von Colombo, Emanuela, Bacigaluppi, Marco, Bartoccetti, Michela, Triolo, Daniela, Bassani, Claudia, Bergamaschi, Andrea, Descamps, Hélène C., Gullotta, Giorgia Serena, Henley, Maria, Piccoli, Marco, Anastasia, Luigi, Pitt, David, Newcombe, Jia, Martino, Gianvito, Farina, Cinthia

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Intestinal Tolerance, with a Little Help from Our Microbial Friends von Descamps, Hélène, Thaiss, Christoph A.

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Interferon-γ/Interleukin-27 Axis Induces Programmed Death Ligand 1 Expression in Monocyte-Derived Dendritic Cells and Restores Immune Tolerance in Central Nervous System Autoimmuni... von Casella, Giacomo, Rasouli, Javad, Thome, Rodolfo, Descamps, Hélène C, Vattikonda, Asrita, Ishikawa, Larissa, Boehm, Alexandra, Hwang, Daniel, Zhang, Weifeng, Xiao, Dan, Park, Jeongho, Zhang, Guang-Xian, Alvarez, Jorge I, Rostami, Abdolmohamad, Ciric, Bogoljub

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β-Hydroxybutyrate suppresses colorectal cancer von Dmitrieva-Posocco, Oxana, Wong, Andrea C., Lundgren, Patrick, Golos, Aleksandra M., Descamps, Hélène C., Dohnalová, Lenka, Cramer, Zvi, Tian, Yuhua, Yueh, Brian, Eskiocak, Onur, Egervari, Gabor, Lan, Yemin, Liu, Jinping, Fan, Jiaxin, Kim, Jihee, Madhu, Bhoomi, Schneider, Kai Markus, Khoziainova, Svetlana, Andreeva, Natalia, Wang, Qiaohong, Li, Ning, Furth, Emma E., Bailis, Will, Kelsen, Judith R., Hamilton, Kathryn E., Kaestner, Klaus H., Berger, Shelley L., Epstein, Jonathan A., Jain, Rajan, Li, Mingyao, Beyaz, Semir, Lengner, Christopher J., Katona, Bryson W., Grivennikov, Sergei I., Thaiss, Christoph A., Levy, Maayan

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IL-27, but not IL-35, inhibits neuroinflammation through modulating GM-CSF expression von Casella, Giacomo, Finardi, Annamaria, Descamps, Hélène, Colombo, Federico, Maiorino, Chiara, Ruffini, Francesca, Patrone, Marco, Degano, Massimo, Martino, Gianvito, Muzio, Luca, Becher, Burkhard, Furlan, Roberto

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A microbiome-dependent gut–brain pathway regulates motivation for exercise von Dohnalová, Lenka, Lundgren, Patrick, Carty, Jamie R. E., Goldstein, Nitsan, Wenski, Sebastian L., Nanudorn, Pakjira, Thiengmag, Sirinthra, Huang, Kuei-Pin, Litichevskiy, Lev, Descamps, Hélène C., Chellappa, Karthikeyani, Glassman, Ana, Kessler, Susanne, Kim, Jihee, Cox, Timothy O., Dmitrieva-Posocco, Oxana, Wong, Andrea C., Allman, Erik L., Ghosh, Soumita, Sharma, Nitika, Sengupta, Kasturi, Cornes, Belinda, Dean, Nitai, Churchill, Gary A., Khurana, Tejvir S., Sellmyer, Mark A., FitzGerald, Garret A., Patterson, Andrew D., Baur, Joseph A., Alhadeff, Amber L., Helfrich, Eric J. N., Levy, Maayan, Betley, J. Nicholas, Thaiss, Christoph A.

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The enteric nervous system relays psychological stress to intestinal inflammation von Schneider, Kai Markus, Blank, Niklas, Alvarez, Yelina, Thum, Katharina, Lundgren, Patrick, Litichevskiy, Lev, Sleeman, Madeleine, Bahnsen, Klaas, Kim, Jihee, Kardo, Simon, Patel, Shaan, Dohnalová, Lenka, Uhr, Giulia T., Descamps, Hélène C., Kircher, Susanna, McSween, Alana M., Ardabili, Ashkan Rezazadeh, Nemec, Kelsey M., Jimenez, Monica T., Glotfelty, Lila G., Eisenberg, Joshua D., Furth, Emma E., Henao-Mejia, Jorge, Bennett, F. Chris, Pierik, Marie J., Romberg-Camps, Mariëlle, Mujagic, Zlatan, Prinz, Marco, Schneider, Carolin V., Wherry, E. John, Bewtra, Meenakshi, Heuckeroth, Robert O., Levy, Maayan, Thaiss, Christoph A.

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NAD precursors cycle between host tissues and the gut microbiome von Chellappa, Karthikeyani, McReynolds, Melanie R, Lu, Wenyun, Zeng, Xianfeng, Makarov, Mikhail, Hayat, Faisal, Mukherjee, Sarmistha, Bhat, Yashaswini R, Lingala, Siddharth R, Shima, Rafaella T, Descamps, Hélène C, Cox, Timothy, Ji, Lixin, Jankowski, Connor, Chu, Qingwei, Davidson, Shawn M, Thaiss, Christoph A, Migaud, Marie E, Rabinowitz, Joshua D, Baur, Joseph A

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A microbiome-dependent gut–brain pathway regulates motivation for exercise von Dohnalová, Lenka, Lundgren, Patrick, Carty, Jamie R. E., Goldstein, Nitsan, Wenski, Sebastian L., Nanudorn, Pakjira, Thiengmag, Sirinthra, Huang, Kuei-Pin, Litichevskiy, Lev, Descamps, Hélène C., Chellappa, Karthikeyani, Glassman, Ana, Kessler, Susanne, Kim, Jihee, Cox, Timothy O., Dmitrieva-Posocco, Oxana, Wong, Andrea C., Allman, Erik L., Ghosh, Soumita, Sharma, Nitika, Sengupta, Kasturi, Cornes, Belinda, Dean, Nitai, Churchill, Gary A., Khurana, Tejvir S., Sellmyer, Mark A., FitzGerald, Garret A., Patterson, Andrew D., Baur, Joseph A., Alhadeff, Amber L., Helfrich, Eric J. N., Levy, Maayan, Betley, J. Nicholas, Thaiss, Christoph A.

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Deep immune profiling of COVID-19 patients reveals distinct immunotypes with therapeutic implications von Mathew, Divij, Giles, Josephine R, Baxter, Amy E, Oldridge, Derek A, Greenplate, Allison R, Wu, Jennifer E, Alanio, Cécile, Kuri-Cervantes, Leticia, Pampena, M Betina, D'Andrea, Kurt, Manne, Sasikanth, Chen, Zeyu, Huang, Yinghui Jane, Reilly, John P, Weisman, Ariel R, Ittner, Caroline A G, Kuthuru, Oliva, Dougherty, Jeanette, Nzingha, Kito, Han, Nicholas, Kim, Justin, Pattekar, Ajinkya, Goodwin, Eileen C, Anderson, Elizabeth M, Weirick, Madison E, Gouma, Sigrid, Arevalo, Claudia P, Bolton, Marcus J, Chen, Fang, Lacey, Simon F, Ramage, Holly, Cherry, Sara, Hensley, Scott E, Apostolidis, Sokratis A, Huang, Alexander C, Vella, Laura A, Betts, Michael R, Meyer, Nuala J, Wherry, E John

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No evidence for persistent enteroviral B infection of pancreatic islets in type 1 diabetic and pre-diabetic patients from RNA-Seq data von Manduchi, Elisabetta, Descamps, Héléne C, Schug, Jonathan, Da, Tong, Lahori, Deeksha, El-Mekkoussi, Hilana, Betts, Michael R, Kaestner, Klaus H

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Modeling type 1 diabetes progression using machine learning and single-cell transcriptomic measurements in human islets von Patil, Abhijeet R., Schug, Jonathan, Liu, Chengyang, Lahori, Deeksha, Descamps, Hélène C., Naji, Ali, Kaestner, Klaus H., Faryabi, Robert B., Vahedi, Golnaz

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Spatiotemporal dynamics during niche remodeling by super-colonizing microbiota in the mammalian gut von Urtecho, Guillaume, Moody, Thomas, Huang, Yiming, Sheth, Ravi U., Richardson, Miles, Descamps, Hélène C., Kaufman, Andrew, Lekan, Opeyemi, Zhang, Zetian, Velez-Cortes, Florencia, Qu, Yiming, Cohen, Lucas, Ricaurte, Deirdre, Gibson, Travis E., Gerber, Georg K., Thaiss, Christoph A., Wang, Harris H.

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Targeting lipid nanoparticles to the blood-brain barrier to ameliorate acute ischemic stroke von Nong, Jia, Glassman, Patrick M., Shuvaev, Vladimir V., Reyes-Esteves, Sahily, Descamps, Helene C., Kiseleva, Raisa Y., Papp, Tyler E., Alameh, Mohamad-Gabriel, Tam, Ying K., Mui, Barbara L., Omo-Lamai, Serena, Zamora, Marco E., Shuvaeva, Tea, Arguiri, Evguenia, Gong, Xijing, Brysgel, Taylor V., Tan, Ai Wen, Woolfork, Ashley G., Weljie, Aalim, Thaiss, Christoph A., Myerson, Jacob W., Weissman, Drew, Kasner, Scott E., Parhiz, Hamideh, Muzykantov, Vladimir R., Brenner, Jacob S., Marcos-Contreras, Oscar A.

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A subpopulation of lipogenic brown adipocytes drives thermogenic memory von Lundgren, Patrick, Sharma, Prateek V., Dohnalová, Lenka, Coleman, Kyle, Uhr, Giulia T., Kircher, Susanna, Litichevskiy, Lev, Bahnsen, Klaas, Descamps, Hélène C., Demetriadou, Christina, Chan, Jacqueline, Chellappa, Karthikeyani, Cox, Timothy O., Heyman, Yael, Pather, Sarshan R., Shoffler, Clarissa, Petucci, Christopher, Shalem, Ophir, Raj, Arjun, Baur, Joseph A., Snyder, Nathaniel W., Wellen, Kathryn E., Levy, Maayan, Seale, Patrick, Li, Mingyao, Thaiss, Christoph A.

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Cytomegalovirus Latent Infection is Associated with an Increased Risk of COVID-19-Related Hospitalization von Alanio, Cécile, Verma, Anurag, Mathew, Divij, Gouma, Sigrid, Liang, Guanxiang, Dunn, Thomas, Oldridge, Derek A, Weaver, JoEllen, Kuri-Cervantes, Leticia, Pampena, M Betina, Betts, Michael R, Collman, Ronald G, Bushman, Frederic D, Meyer, Nuala J, Hensley, Scott E, Rader, Daniel, Wherry, E John

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