Metformin reduces cell migration and down-regulates epithelial to mesenchymal transition by AMPK / Foxo3a pathway in human intrahepatic cholangiocarcinoma von Di Matteo, S, Lustri, A, Costantini, D, Nevi, L, Manzi, E, Napoletano, C, Faccioli, J, Giulitti, F, DeRose, A.M, Bragazzi, M.C, Grazi, G, Berloco, P.B, Giuliante, F, Cardinale, V, Carpino, G, Alvaro, D

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Metformin reduces cell migration and down-regulates epithelial to mesenchymal transition (EMT) by AMPK/Foxo3a pathway in human intrahepatic cholangiocarcinoma (CCA) von Di Matteo, S, Costantini, D, Nevi, L, Lustri, A, Napoletano, C, Faccioli, J, Giulitti, F, Manzi, E, DeRose, A.M, Bragazzi, M.C, Grazi, G, Berloco, P.B, Giuliante, F, Cardinale, V, Carpino, G, Alvaro, D

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P58 HUMAN CHOLANGIOCARCINOMA (CCA) AND CCA CANCER STEM CELLS (CSCS) ARE HIGHLY SENSITIVE TO THE ANTIPROLIFERATIVE EFFECTS OF PI3-KINASE INHIBITORS von Fraveto, A, Torrice, A, Bragazzi, M.C, Renzi, A, Carpino, G, Giuliante, F, DeRose, A.M, Grazi, G, Cardinale, V, Onori, P, Franchitto, A, Napoletano, C, Gentile, R, Gaudio, E, Alvaro, D

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P44 TUMORIGENIC POTENTIAL OF CANCER STEM CELLS (CSCS) ISOLATED FROM HUMAN CHOLANGIOCARCINOMA (CCA) SUBTYPES von Torrice, A, Carpino, G, Fraveto, A, Renzi, A, Bragazzi, M.C, Giuliante, F, Derose, A.M, Cardinale, V, Gentile, R, Onori, P, Napoletano, C, Franchitto, A, Cantafora, A, Grazi, G, D'Argenio, G, Caporaso, N, Gaudio, E, Alvaro, D

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Tumorigenic potential of cancer stem cells (CSCs) isolated from human cholangiocarcinoma (CCA) subtypes in cirrhotic liver von Torrice, A, Carpino, G, Fraveto, A, Renzi, A, Bragazzi, M.C, Giuliante, F, Derose, A.M, Cardinale, V, Gentile, R, Onori, P, Napoletano, C, Franchitto, A, Cantafora, A, D’Argenio, G, Caporaso, N, Grazi, G, Gaudio, E, Alvaro, D

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OC.19.5 TUMORIGENIC POTENTIAL OF CANCER STEM CELLS (CSCS) ISOLATED FROM HUMAN CHOLANGIOCARCINOMA (CCA) SUBTYPES von Torrice, A, Carpino, G, Fraveto, A, Renzi, A, Bragazzi, M.C, Giuliante, F, Derose, A.M, Cardinale, V, Gentile, R, Onori, P, Napoletano, C, Franchitto, A, Cantafora, A, Grazi, G, Gaudio, E, Alvaro, D

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OC.19.3 HUMAN CHOLANGIOCARCINOMA (CCA) AND CCA CANCER STEM CELLS (CSCS) ARE HIGHLY SENSITIVE TO THE ANTIPROLIFERATIVE EFFECTS OF PI3-KINASE INHIBITORS von Fraveto, A, Torrice, A, Bragazzi, M.C, Renzi, A, Carpino, G, Giuliante, F, Derose, A.M, Grazi, G, Cardinale, V, Onori, P, Franchitto, A, Napoletano, C, Gentile, R, Gaudio, E, Alvaro, D

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Human cholangiocarcinoma (CCA) and CCA cancer stem cells (CSCs) are highly sensitive to the antiproliferative effects of PI3-kinase inhibitors von Fraveto, A, Torrice, A, Bragazzi, M.C, Renzi, A, Carpino, G, Giuliante, F, DeRose, A.M, Grazi, G, Cardinale, V, Onori, P, Franchitto, A, Napoletano, C, Gentile, R, Gaudio, E, Alvaro, D

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Tumorigenic potential of cancer stem cells (CSCs) isolated from human cholangiocarcinoma (CCA) subtypes von Torrice, A, Carpino, G, Fraveto, A, Renzi, A, Bragazzi, M.C, Giuliante, F, Derose, A.M, Cardinale, V, Gentile, R, Onori, P, Napoletano, C, Franchitto, A, Cantafora, A, Grazi, G, D’Argenio, G, Caporaso, N, Gaudio, E, Alvaro, D

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SAT-116 - Metformin reduces cell migration and down-regulates epithelial to mesenchymal transition by AMPK / Foxo3a pathway in human intrahepatic cholangiocarcinoma von Di Matteo, S., Lustri, A., Costantini, D., Nevi, L., Manzi, E., Napoletano, C., Faccioli, J., Giulitti, F., DeRose, A.M., Bragazzi, M.C., Grazi, G., Berloco, P.B., Giuliante, F., Cardinale, V., Carpino, G., Alvaro, D.

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OC.08.2 THE FXR AGONIST, OBETICHOLIC ACID, INHIBITS THE CANCEROGENIC POTENTIAL OF PRIMARY HUMAN CHOLANGIOCARCINOMA CELLS: A STUDY ON PRIMARY HUMAN CELL CULTURES von Di Matteo, S., Nevi, L., Costantini, D., Colantonio, M., Giulitti, F., Napoletano, C., Safarikia, S., Manzi, E., Derose, A.M., Meandro, F., Bragazzi, M.C., Grazi, G., Berloco, P.B., Giuliante, F., Carpino, G., Cardinale, V., Gaudio, E., Alvaro, D.

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The cancerogenic potential of primary human Cholangioracinoma cells is inhibited by Obeticholic Acid, a Farnesoid X Receptor (FXR) agonist von Di Matteo, S., Nevi, L., Costantini, D., Colantonio, M., Giulitti, F., Napoletano, C., Safarikia, S., Manzi, E., Derose, A.M., Melandro, F., Bragazzi, M.C., Grazi, G., Berloco, P.B., Giuliante, F., Carpino, G., Cardinale, V., Gaudio, E., Alvaro, D.

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Specific human cholangiocarcinoma (CCA) subpopulations of cancer stem cells (CSCs) express DoubleCortin-Like Kinase 1 (DCLK1) and DCLK1 inhibition induces anti-cancer effects von Nevi, L., Di Matteo, S., Carpino, G., Cardinale, V., Zizzari, I., Ambrosino, V., Costantini, D., Safarikia, S., Manzi, E., Derose, A.M., Melandro, F., Bragazzi, M.C., Grazi, G., Berloco, P.B., Giuliante, F., Gaudio, E., Alvaro, D.

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Identification of DNA-cisplatin adducts in a blind trial of in situ scanning tunneling microscopy von Jeffrey, A.M., Jing, T.W., DeRose, J.A., Vaught, A., Rekesh, D., Lu, F.-X., Lindsay, S.M.

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Sterol and steryl ester regulation of phospholipase A2 from the Mosquito parasite Lagenidium giganteum von Kerwin, J.L, MacKichan, J.K, Semon, M.J, Wiens, A.M, DeRose, C.C, Iorvik, J.J

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