Discovery of a Novel and Selective Indoleamine 2,3-Dioxygenase (IDO-1) Inhibitor 3‑(5-Fluoro‑1H‑indol-3-yl)pyrrolidine-2,5-dione (EOS200271/PF-06840003) and Its Characterization as... von Crosignani, Stefano, Bingham, Patrick, Bottemanne, Pauline, Cannelle, Hélène, Cauwenberghs, Sandra, Cordonnier, Marie, Dalvie, Deepak, Deroose, Frederik, Feng, Jun Li, Gomes, Bruno, Greasley, Samantha, Kaiser, Stephen E, Kraus, Manfred, Négrerie, Michel, Maegley, Karen, Miller, Nichol, Murray, Brion W, Schneider, Manfred, Soloweij, James, Stewart, Albert E, Tumang, Joseph, Torti, Vince R, Van Den Eynde, Benoit, Wythes, Martin

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In Vivo Inhibition of RIPK2 Kinase Alleviates Inflammatory Disease von Tigno-Aranjuez, Justine T., Benderitter, Pascal, Rombouts, Frederik, Deroose, Frederik, Bai, XiaoDong, Mattioli, Benedetta, Cominelli, Fabio, Pizarro, Theresa T., Hoflack, Jan, Abbott, Derek W.

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Open Source Drug Discovery: Highly Potent Antimalarial Compounds Derived from the Tres Cantos Arylpyrroles von Williamson, Alice E, Ylioja, Paul M, Robertson, Murray N, Antonova-Koch, Yevgeniya, Avery, Vicky, Baell, Jonathan B, Batchu, Harikrishna, Batra, Sanjay, Burrows, Jeremy N, Bhattacharyya, Soumya, Calderon, Felix, Charman, Susan A, Clark, Julie, Crespo, Benigno, Dean, Matin, Debbert, Stefan L, Delves, Michael, Dennis, Adelaide S. M, Deroose, Frederik, Duffy, Sandra, Fletcher, Sabine, Giaever, Guri, Hallyburton, Irene, Gamo, Francisco-Javier, Gebbia, Marinella, Guy, R. Kiplin, Hungerford, Zoe, Kirk, Kiaran, Lafuente-Monasterio, Maria J, Lee, Anna, Meister, Stephan, Nislow, Corey, Overington, John P, Papadatos, George, Patiny, Luc, Pham, James, Ralph, Stuart A, Ruecker, Andrea, Ryan, Eileen, Southan, Christopher, Srivastava, Kumkum, Swain, Chris, Tarnowski, Matthew J, Thomson, Patrick, Turner, Peter, Wallace, Iain M, Wells, Timothy N. C, White, Karen, White, Laura, Willis, Paul, Winzeler, Elizabeth A, Wittlin, Sergio, Todd, Matthew H

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Synthesis of 1-Boc-3-fluoroazetidine-3-carboxylic Acid von Van Hende, Eva, Verniest, Guido, Deroose, Frederik, Thuring, Jan-Willem, Macdonald, Gregor, De Kimpe, Norbert

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Synthesis of aminomethylated 4-fluoropiperidines and 3-fluoropyrrolidines von Verniest, Guido, Piron, Karel, Van Hende, Eva, Thuring, Jan Willem, Macdonald, Gregor, Deroose, Frederik, De Kimpe, Norbert

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A General and Highly Efficient Solid Phase Synthesis of Oligosaccharides. Total Synthesis of a Heptasaccharide Phytoalexin Elicitor (HPE) von Nicolaou, K. C, Winssinger, Nicolas, Pastor, Joaquín, DeRoose, Frederik

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Synthesis of 3-Amino-4-fluoropyrazoles von Surmont, Riccardo, Verniest, Guido, De Schrijver, Mathias, Thuring, Jan Willem, ten Holte, Peter, Deroose, Frederik, De Kimpe, Norbert

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Synthesis of 4-Substituted 3,3-Difluoropiperidines von Surmont, Riccardo, Verniest, Guido, Thuring, Jan Willem, Macdonald, Gregor, Deroose, Frederik, De Kimpe, Norbert

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Novel Enantioselective Syntheses of (+)-Biotin von Deroose, Frederik D, Clercq, Pierre J. De

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Synthesis and biological evaluation of imidazol-2-one and 2-cyanoiminoimidazole derivatives: novel series of PDE4 inhibitors von Andrés, J.Ignacio, Alonso, José M, Dı́az, Adolfo, Fernández, Javier, Iturrino, Laura, Martı́nez, Pedro, Matesanz, Encarna, Freyne, Eddy J, Deroose, Frederik, Boeckx, Gustaaf, Petit, Davy, Diels, Gaston, Megens, Anton, Somers, Marijke, Wauwe, Jean Van, Stoppie, Paul, Cools, Marina, Clerck, Fred De, Peeters, Danielle, de Chaffoy, Didier

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New Synthesis of 3-Fluoropyrroles von Surmont, Riccardo, Verniest, Guido, Colpaert, Filip, Macdonald, Gregor, Thuring, Jan Willem, Deroose, Frederik, De Kimpe, Norbert

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Synthesis of gem-difluorinated 1,6-naphthyridine-5,7-diones von Piron, Karel, Kenis, Sara, Verniest, Guido, Surmont, Riccardo, Thuring, Jan Willem, ten Holte, Peter, Deroose, Frederik, De Kimpe, Norbert

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Synthesis of 5-amino- and 5-hydroxy-3,3-difluoropiperidines von Surmont, Riccardo, Verniest, Guido, Thuring, Jan Willem, Ten Holte, Peter, Deroose, Frederik, De Kimpe, Norbert

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New Entries toward 3,3-Difluoropiperidines von Verniest, Guido, Surmont, Riccardo, Hende, Eva Van, Deweweire, Arvid, Deroose, Frederik, Thuring, Jan Willem, De Kimpe, Norbert

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Synthesis of 2-aryl-3-hydroxymethyl-5,5-difluoropiperidines von Moens, Matthias, Verniest, Guido, De Schrijver, Matthias, ten Holte, Peter, Thuring, Jan-Willem, Deroose, Frederik, De Kimpe, Norbert

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Synthesis of 5-amino- and 5-hydroxy-3,3-difluoropiperidinesElectronic supplementary information (ESI) available: Experimental procedures and spectroscopic data for compounds 5a, 6b... von Surmont, Riccardo, Verniest, Guido, Thuring, Jan Willem, ten Holte, Peter, Deroose, Frederik, De Kimpe, Norbert

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Synthesis of aminomethylated 4-fluoropiperidines and 3-fluoropyrrolidinesElectronic supplementary information (ESI) available: Experimental procedures and spectroscopic data for co... von Verniest, Guido, Piron, Karel, Van Hende, Eva, Thuring, Jan Willem, Macdonald, Gregor, Deroose, Frederik, De Kimpe, Norbert

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Synthesis and Biological Evaluation of Methylene-Bridged Analogs of the Potent Cannabinoid Receptor Antagonist Rimonabant von Ślusarczyk, Magdalena, De Borggraeve, Wim M., Hoornaert, Georges, Deroose, Frederik, Linders, Joannes T. M.

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Design and Synthesis of a Series of Piperazine‐1‐carboxamidine Derivatives with Antifungal Activity Resulting from Accumulation of Endogenous Reactive Oxygen Species von François, Isabelle E., Thevissen, Karin, Pellens, Klaartje, Meert, Els M., Heeres, Jan, Freyne, Eddy, Coesemans, Erwin, Viellevoye, Marcel, Deroose, Frederik, Martinez Gonzalez, Sonia, Pastor, Joaquin, Corens, David, Meerpoel, Lieven, Borgers, Marcel, Ausma, Jannie, Dispersyn, Gerrit D., Cammue, Bruno P.

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Open Source Drug Discovery: Highly Potent Antimalarial Compounds Derived from the Tres Cantos Arylpyrroles von Williamson, Alice E, Ylioja, Paul M, Robertson, Murray N, Antonova-Koch, Yevgeniya, Avery, Vicky, Baell, Jonathan B, Batchu, Harikrishna, Batra, Sanjay, Burrows, Jeremy N, Bhattacharyya, Soumya, Calderon, Felix, Charman, Susan A, Clark, Julie, Crespo, Benigno, Dean, Matin, Debbert, Stefan L, Delves, Michael, Dennis, Adelaide SM, Deroose, Frederik, Duffy, Sandra, Fletcher, Sabine, Giaever, Guri, Hallyburton, Irene, Gamo, Francisco-Javier, Gebbia, Marinella, Guy, R Kiplin, Hungerford, Zoe, Kirk, Kiaran, Lafuente-Monasterio, Maria J, Lee, Anna, Meister, Stephan, Nislow, Corey, Overington, John P, Papadatos, George, Patiny, Luc, Pham, James, Ralph, Stuart A, Ruecker, Andrea, Ryan, Eileen, Southan, Christopher, Srivastava, Kumkum, Swain, Chris, Tarnowski, Matthew J, Thomson, Patrick, Turner, Peter, Wallace, Iain M, Wells, Timothy NC, White, Karen, White, Laura, Willis, Paul, Winzeler, Elizabeth A, Wittlin, Sergio, Todd, Matthew H

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