The MBOAT7-TMC4 Variant rs641738 Increases Risk of Nonalcoholic Fatty Liver Disease in Individuals of European Descent von Mancina, Rosellina Margherita, Dongiovanni, Paola, Petta, Salvatore, Pingitore, Piero, Meroni, Marica, Rametta, Raffaela, Borén, Jan, Montalcini, Tiziana, Pujia, Arturo, Wiklund, Olov, Hindy, George, Spagnuolo, Rocco, Motta, Benedetta Maria, Pipitone, Rosaria Maria, Craxì, Antonio, Fargion, Silvia, Nobili, Valerio, Käkelä, Pirjo, Kärjä, Vesa, Männistö, Ville, Pihlajamäki, Jussi, Reilly, Dermot F, Castro-Perez, Jose, Kozlitina, Julia, Valenti, Luca, Romeo, Stefano

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Relation of plasma ceramides to visceral adiposity, insulin resistance and the development of type 2 diabetes mellitus: the Dallas Heart Study von Neeland, Ian J., Singh, Shruti, McGuire, Darren K., Vega, Gloria L., Roddy, Thomas, Reilly, Dermot F., Castro-Perez, Jose, Kozlitina, Julia, Scherer, Philipp E.

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Estimation of kinship coefficient in structured and admixed populations using sparse sequencing data von Dou, Jinzhuang, Sun, Baoluo, Sim, Xueling, Hughes, Jason D, Reilly, Dermot F, Tai, E Shyong, Liu, Jianjun, Wang, Chaolong

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Peripheral Circadian Clocks in the Vasculature von Reilly, Dermot F, Westgate, Elizabeth J, FitzGerald, Garret A

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Genetic Components of the Circadian Clock Regulate Thrombogenesis In Vivo von WESTGATE, Elizabeth J, YAN CHENG, REILLY, Dermot F, PRICE, Tom S, WALISSER, Jacqueline A, BRADFIELD, Christopher A, FITZGERALD, Garret A

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Polygenic Risk Score Identifies Subgroup With Higher Burden of Atherosclerosis and Greater Relative Benefit From Statin Therapy in the Primary Prevention Setting von Natarajan, Pradeep, Young, Robin, Stitziel, Nathan O, Padmanabhan, Sandosh, Baber, Usman, Mehran, Roxana, Sartori, Samantha, Fuster, Valentin, Reilly, Dermot F, Butterworth, Adam, Rader, Daniel J, Ford, Ian, Sattar, Naveed, Kathiresan, Sekar

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Discovering metabolic disease gene interactions by correlated effects on cellular morphology von Jiao, Yang, Ahmed, Umer, Sim, M.F. Michelle, Bejar, Andrea, Zhang, Xiaolan, Talukder, M. Mesbah Uddin, Rice, Robert, Flannick, Jason, Podgornaia, Anna I., Reilly, Dermot F., Engreitz, Jesse M., Kost-Alimova, Maria, Hartland, Kate, Mercader, Josep-Maria, Georges, Sara, Wagh, Vilas, Tadin-Strapps, Marija, Doench, John G., Edwardson, J. Michael, Rochford, Justin J., Rosen, Evan D., Majithia, Amit R.

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The Use of Genomics to Drive Kidney Disease Drug Discovery and Development von Reilly, Dermot F, Breyer, Matthew D

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Association of G6PD variants with hemoglobin A1c and impact on diabetes diagnosis in East Asian individuals von Leong, Aaron, Lim, Victor Jun Yu, Wang, Chaolong, Chai, Jin-Fang, Dorajoo, Rajkumar, Heng, Chew-Kiat, van Dam, Rob M, Koh, Woon-Puay, Yuan, Jian-Min, Jonas, Jost B, Wang, Ya Xing, Wei, Wen-Bin, Liu, Jianjun, Reilly, Dermot F, Wong, Tien-Yin, Cheng, Ching-Yu, Sim, Xueling

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Association of APOC3  Loss-of-Function Mutations With Plasma Lipids and Subclinical Atherosclerosis von Natarajan, Pradeep, MD, MMSc, Kohli, Puja, MD, Baber, Usman, MD, Nguyen, Khanh-Dung H., PhD, Sartori, Samantha, PhD, Reilly, Dermot F., PhD, Mehran, Roxana, MD, Muntendam, Pieter, PhD, Fuster, Valentin, MD, PhD, Rader, Daniel J., MD, Kathiresan, Sekar, MD

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Phenome-wide association studies across large population cohorts support drug target validation von Diogo, Dorothée, Tian, Chao, Franklin, Christopher S., Alanne-Kinnunen, Mervi, March, Michael, Spencer, Chris C. A., Vangjeli, Ciara, Weale, Michael E., Mattsson, Hannele, Kilpeläinen, Elina, Sleiman, Patrick M. A., Reilly, Dermot F., McElwee, Joshua, Maranville, Joseph C., Chatterjee, Arnaub K., Bhandari, Aman, Nguyen, Khanh-Dung H., Estrada, Karol, Reeve, Mary-Pat, Hutz, Janna, Bing, Nan, John, Sally, MacArthur, Daniel G., Salomaa, Veikko, Ripatti, Samuli, Hakonarson, Hakon, Daly, Mark J., Palotie, Aarno, Hinds, David A., Donnelly, Peter, Fox, Caroline S., Day-Williams, Aaron G., Plenge, Robert M., Runz, Heiko

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The genetic background shapes the susceptibility to mitochondrial dysfunction and NASH progression von Benegiamo, Giorgia, von Alvensleben, Giacomo V G, Rodríguez-López, Sandra, Goeminne, Ludger J E, Bachmann, Alexis M, Morel, Jean-David, Broeckx, Ellen, Ma, Jing Ying, Carreira, Vinicius, Youssef, Sameh A, Azhar, Nabil, Reilly, Dermot F, D'Aquino, Katharine, Mullican, Shannon, Bou-Sleiman, Maroun, Auwerx, Johan

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Peripheral Circadian Clock Rhythmicity Is Retained in the Absence of Adrenergic Signaling von Reilly, Dermot F, Curtis, Anne M, Cheng, Yan, Westgate, Elizabeth J, Rudic, Radu D, Paschos, Georgios, Morris, Jacqueline, Ouyang, Ming, Thomas, Steven A, FitzGerald, Garret A

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243-OR: A Novel Platform for Genetic Screening of NAFLD-Associated Genes Identifies UBE2G2 and Other Genes That Alter Hepatic Lipid Accumulation von HU, SIQI, ADITI SRI VAISHNAVI KHANDAVILLI, SESHA, DIAO, RACHEL Y., RAUM, JEFFREY, AZHAR, NABIL, BAKAJ, IVONA, COWLEY, GLENN, RADY, BRIAN, REILLY, DERMOT F., MAJITHIA, AMIT R.

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Plasma Levels of Risk-Variant APOL1 Do Not Associate with Renal Disease in a Population-Based Cohort von Kozlitina, Julia, Zhou, Haihong, Brown, Patricia N, Rohm, Rory J, Pan, Yi, Ayanoglu, Gulesi, Du, Xiaoyan, Rimmer, Eric, Reilly, Dermot F, Roddy, Thomas P, Cully, Doris F, Vogt, Thomas F, Blom, Daniel, Hoek, Maarten

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DGAT2 Inhibition Alters Aspects of Triglyceride Metabolism in Rodents but Not in Non-human Primates von McLaren, David G., Han, Seongah, Murphy, Beth Ann, Wilsie, Larissa, Stout, Steven J., Zhou, Haihong, Roddy, Thomas P., Gorski, Judith N., Metzger, Daniel E., Shin, Myung K., Reilly, Dermot F., Zhou, Heather H., Tadin-Strapps, Marija, Bartz, Steven R., Cumiskey, Anne-Marie, Graham, Thomas H., Shen, Dong-Ming, Akinsanya, Karen O., Previs, Stephen F., Imbriglio, Jason E., Pinto, Shirly

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Association of APOC3 Loss-of-Function Mutations With Plasma Lipids and Subclinical Atherosclerosis: The Multi-Ethnic BioImage Study von Natarajan, Pradeep, Kohli, Puja, Baber, Usman, Nguyen, Khanh-Dung H., Sartori, Samantha, Reilly, Dermot F., Mehran, Roxana, Muntendam, Pieter, Fuster, Valentin, Rader, Daniel J., Kathiresan, Sekar

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Using off-target data from whole-exome sequencing to improve genotyping accuracy, association analysis and polygenic risk prediction von Dou, Jinzhuang, Wu, Degang, Ding, Lin, Wang, Kai, Jiang, Minghui, Chai, Xiaoran, Reilly, Dermot F, Tai, E Shyong, Liu, Jianjun, Sim, Xueling, Cheng, Shanshan, Wang, Chaolong

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Genome-Wide Association for HbA1c in Malay Identified Deletion on SLC4A1 that Influences HbA1c Independent of Glycemia von Chai, Jin-Fang, Kao, Shih-Ling, Wang, Chaolong, Lim, Victor Jun-Yu, Khor, Ing Wei, Dou, Jinzhuang, Podgornaia, Anna I, Chothani, Sonia, Cheng, Ching-Yu, Sabanayagam, Charumathi, Wong, Tien-Yin, van Dam, Rob M, Liu, Jianjun, Reilly, Dermot F, Paterson, Andrew D, Sim, Xueling

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Genetic invalidation of Lp-PLA2 as a therapeutic target: Large-scale study of five functional Lp-PLA2-lowering alleles von Gregson, John M, Freitag, Daniel F, Surendran, Praveen, Stitziel, Nathan O, Chowdhury, Rajiv, Burgess, Stephen, Kaptoge, Stephen, Gao, Pei, Staley, James R, Willeit, Peter, Nielsen, Sune F, Caslake, Muriel, Trompet, Stella, Polfus, Linda M, Kuulasmaa, Kari, Kontto, Jukka, Perola, Markus, Blankenberg, Stefan, Veronesi, Giovanni, Gianfagna, Francesco, Männistö, Satu, Kimura, Akinori, Lin, Honghuang, Reilly, Dermot F, Gorski, Mathias, Mijatovic, Vladan, Munroe, Patricia B, Ehret, Georg B, Thompson, Alex, Uria-Nickelsen, Maria, Malarstig, Anders, Dehghan, Abbas, Vogt, Thomas F, Sasaoka, Taishi, Takeuchi, Fumihiko, Kato, Norihiro, Yamada, Yoshiji, Kee, Frank, Müller-Nurasyid, Martina, Ferrières, Jean, Arveiler, Dominique, Amouyel, Philippe, Salomaa, Veikko, Boerwinkle, Eric, Thompson, Simon G, Ford, Ian, Wouter Jukema, J, Sattar, Naveed, Packard, Chris J, Shafi Majumder, Abdulla al, Alam, Dewan S, Deloukas, Panos, Schunkert, Heribert, Samani, Nilesh J, Kathiresan, Sekar, Nordestgaard, Børge G, Saleheen, Danish, Howson, Joanna MM, Di Angelantonio, Emanuele, Butterworth, Adam S, Danesh, John

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