Loss of E-Cadherin-Dependent Cell-Cell Adhesion and the Development and Progression of Cancer von Bruner, Heather C, Derksen, Patrick W B

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NCAM-induced focal adhesion assembly: a functional switch upon loss of E-cadherin von Lehembre, Francois, Yilmaz, Mahmut, Wicki, Andreas, Schomber, Tibor, Strittmatter, Karin, Ziegler, Dominik, Kren, Angelika, Went, Phillip, Derksen, Patrick WB, Berns, Anton, Jonkers, Jos, Christofori, Gerhard

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The laminin–keratin link shields the nucleus from mechanical deformation and signalling von Kechagia, Zanetta, Sáez, Pablo, Gómez-González, Manuel, Canales, Brenda, Viswanadha, Srivatsava, Zamarbide, Martín, Andreu, Ion, Koorman, Thijs, Beedle, Amy E. M., Elosegui-Artola, Alberto, Derksen, Patrick W. B., Trepat, Xavier, Arroyo, Marino, Roca-Cusachs, Pere

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Spatial collagen stiffening promotes collective breast cancer cell invasion by reinforcing extracellular matrix alignment von Koorman, Thijs, Jansen, Karin A., Khalil, Antoine, Haughton, Peter D., Visser, Daan, Rätze, Max A. K., Haakma, Wisse E., Sakalauskaitè, Gabrielè, van Diest, Paul J., de Rooij, Johan, Derksen, Patrick W. B.

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Small molecules to regulate the GH/IGF1 axis by inhibiting the growth hormone receptor synthesis von van der Velden, Lieke M., Maas, Peter, van Amersfoort, Miranda, Timmermans-Sprang, Elpetra P M., Mensinga, Anneloes, van der Vaart, Elisabeth, Malergue, Fabrice, Viëtor, Henk, Derksen, Patrick W B., Klumperman, Judith, van Agthoven, Andreas, Egan, David A., Mol, Jan A., Strous, Ger J.

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Nuclear Kaiso expression is associated with high grade and triple-negative invasive breast cancer von Vermeulen, Jeroen F, van de Ven, Robert A H, Ercan, Cigdem, van der Groep, Petra, van der Wall, Elsken, Bult, Peter, Christgen, Matthias, Lehmann, Ulrich, Daniel, Juliet, van Diest, Paul J, Derksen, Patrick W B

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Hypoxia-Targeting Fluorescent Nanobodies for Optical Molecular Imaging of Pre-Invasive Breast Cancer von van Brussel, Aram S. A., Adams, Arthur, Oliveira, Sabrina, Dorresteijn, Bram, El Khattabi, Mohamed, Vermeulen, Jeroen F., van der Wall, Elsken, Mali, Willem P. Th. M., Derksen, Patrick W. B., van Diest, Paul J., van Bergen en Henegouwen, Paul M. P.

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Reporting on invasive lobular breast cancer in clinical trials: a systematic review von Van Baelen, Karen, Van Cauwenberge, Josephine, Maetens, Marion, Beck, Gabriela, Camden, Ann, Chase, Megan-Claire, Fraser, Valerie, Freeney, Siobhan, Hutcheson, Laurie, Levine, Julia K., Lien, Tone, Terveer, Rian, Turner, Claire, Senkus, Elzbieta, Jankowitz, Rachel C., Vandecaveye, Vincent, Floris, Giuseppe, Neven, Patrick, Wildiers, Hans, Sawyer, Elinor, Vincent-Salomon, Anne, Derksen, Patrick W. B., Desmedt, Christine

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High sensitivity of BRCA1-deficient mammary tumors to the PARP inhibitor AZD2281 alone and in combination with platinum drugs von Rottenberg, Sven, Jaspers, Janneke E, Kersbergen, Ariena, van der Burg, Eline, Nygren, Anders O.H, Zander, Serge A.L, Derksen, Patrick W.B, de Bruin, Michiel, Zevenhoven, John, Lau, Alan, Boulter, Robert, Cranston, Aaron, O'Connor, Mark J, Martin, Niall M.B, Borst, Piet, Jonkers, Jos

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Differential transcriptional invasion signatures from patient derived organoid models define a functional prognostic tool for head and neck cancer von Haughton, Peter D., Haakma, Wisse, Chalkiadakis, Theofilos, Breimer, Gerben E., Driehuis, Else, Clevers, Hans, Willems, Stefan, Prekovic, Stefan, Derksen, Patrick W. B.

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Lobular breast cancer: molecular basis, mouse and cellular models von Christgen, Matthias, Derksen, Patrick W B

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E-cadherin to P-cadherin switching in lobular breast cancer with tubular elements von Christgen, Matthias, Bartels, Stephan, van Luttikhuizen, Jana L., Bublitz, Janin, Rieger, Luisa U., Christgen, Henriette, Stark, Helge, Sander, Bjoern, Lehmann, Ulrich, Steinemann, Doris, Derksen, Patrick W.B., Kreipe, Hans

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p120-Catenin Is Critical for the Development of Invasive Lobular Carcinoma in Mice von Tenhagen, Milou, Klarenbeek, Sjoerd, Braumuller, Tanya M., Hofmann, Ilse, van der Groep, Petra, ter Hoeve, Natalie, van der Wall, Elsken, Jonkers, Jos, Derksen, Patrick W. B.

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Results of a worldwide survey on the currently used histopathological diagnostic criteria for invasive lobular breast cancer von De Schepper, Maxim, Vincent-Salomon, Anne, Christgen, Matthias, Van Baelen, Karen, Richard, François, Tsuda, Hitoshi, Kurozumi, Sasagu, Brito, Maria Jose, Cserni, Gabor, Schnitt, Stuart, Larsimont, Denis, Kulka, Janina, Fernandez, Pedro Luis, Rodríguez-Martínez, Paula, Olivar, Ana Aula, Melendez, Cristina, Van Bockstal, Mieke, Kovacs, Aniko, Varga, Zsuzsanna, Wesseling, Jelle, Bhargava, Rohit, Boström, Pia, Franchet, Camille, Zambuko, Blessing, Matute, Gustavo, Mueller, Sophie, Berghian, Anca, Rakha, Emad, van Diest, Paul J., Oesterreich, Steffi, Derksen, Patrick W.B., Floris, Giuseppe, Desmedt, Christine

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Cell surface proteoglycan syndecan-1 mediates hepatocyte growth factor binding and promotes Met signaling in multiple myeloma von Derksen, Patrick W.B., Keehnen, Robert M.J., Evers, Ludo M., van Oers, Marinus H.J., Spaargaren, Marcel, Pals, Steven T.

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Chemotherapy Enhances Metastasis Formation via VEGFR-1-Expressing Endothelial Cells von DAENEN, Laura G. M, ROODHART, Jeanine M. L, VAN AMERSFOORT, Miranda, DEHNAD, Mantre, ROESSINGH, Wijnand, ULFMAN, Laurien H, DERKSEN, Patrick W. B, VOEST, Emile E

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Loss of E-cadherin leads to Id2-dependent inhibition of cell cycle progression in metastatic lobular breast cancer von Rätze, Max A. K., Koorman, Thijs, Sijnesael, Thijmen, Bassey-Archibong, Blessing, van de Ven, Robert, Enserink, Lotte, Visser, Daan, Jaksani, Sridevi, Viciano, Ignacio, Bakker, Elvira R. M., Richard, François, Tutt, Andrew, O’Leary, Lynda, Fitzpatrick, Amanda, Roca-Cusachs, Pere, van Diest, Paul J., Desmedt, Christine, Daniel, Juliet M., Isacke, Clare M., Derksen, Patrick W. B.

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p120-catenin in cancer - mechanisms, models and opportunities for intervention von Schackmann, Ron C J, Tenhagen, Milou, van de Ven, Robert A H, Derksen, Patrick W B

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Somatic inactivation of E-cadherin and p53 in mice leads to metastatic lobular mammary carcinoma through induction of anoikis resistance and angiogenesis von Derksen, Patrick W.B., Liu, Xiaoling, Saridin, Francis, van der Gulden, Hanneke, Zevenhoven, John, Evers, Bastiaan, van Beijnum, Judy R., Griffioen, Arjan W., Vink, Jacqueline, Krimpenfort, Paul, Peterse, Johannes L., Cardiff, Robert D., Berns, Anton, Jonkers, Jos

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Atlas of Lobular Breast Cancer Models: Challenges and Strategic Directions von Sflomos, George, Schipper, Koen, Koorman, Thijs, Fitzpatrick, Amanda, Oesterreich, Steffi, Lee, Adrian V, Jonkers, Jos, Brunton, Valerie G, Christgen, Matthias, Isacke, Clare, Derksen, Patrick W B, Brisken, Cathrin

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