Mining the LIPG allelic spectrum reveals the contribution of rare and common regulatory variants to HDL cholesterol von Khetarpal, Sumeet A, Edmondson, Andrew C, Raghavan, Avanthi, Neeli, Hemanth, Jin, Weijun, Badellino, Karen O, Demissie, Serkalem, Manning, Alisa K, DerOhannessian, Stephanie L, Wolfe, Megan L, Cupples, L Adrienne, Li, Mingyao, Kathiresan, Sekar, Rader, Daniel J

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Loss-of-function variants in endothelial lipase are a cause of elevated HDL cholesterol in humans von Edmondson, Andrew C, Brown, Robert J, Kathiresan, Sekar, Cupples, L Adrienne, Demissie, Serkalem, Manning, Alisa Knodle, Jensen, Majken K, Rimm, Eric B, Wang, Jian, Rodrigues, Amrith, Bamba, Vaneeta, Khetarpal, Sumeet A, Wolfe, Megan L, Derohannessian, Stephanie, Li, Mingyao, Reilly, Muredach P, Aberle, Jens, Evans, David, Hegele, Robert A, Rader, Daniel J

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Genetic Variants Associated With Plasma Lipids Are Associated With the Lipid Response to Niacin von Tuteja, Sony, Qu, Liming, Vujkovic, Marijana, Dunbar, Richard L, Chen, Jinbo, DerOhannessian, Stephanie, Rader, Daniel J

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Integrative genomics identifies 7p11.2 as a novel locus for fever and clinical stress response in humans von Ferguson, Jane F, Meyer, Nuala J, Qu, Liming, Xue, Chenyi, Liu, Yichuan, DerOhannessian, Stephanie L, Rushefski, Melanie, Paschos, Georgios K, Tang, Soonyew, Schadt, Eric E, Li, Mingyao, Christie, Jason D, Reilly, Muredach P

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ATP-Binding Cassette Transporter A1 Deficiency in Human Induced Pluripotent Stem Cell-Derived Hepatocytes Abrogates HDL Biogenesis and Enhances Triglyceride Secretion von Bi, Xin, Pashos, Evanthia E., Cuchel, Marina, Lyssenko, Nicholas N., Hernandez, Mayda, Picataggi, Antonino, McParland, James, Yang, Wenli, Liu, Ying, Yan, Ruilan, Yu, Christopher, DerOhannessian, Stephanie L., Phillips, Michael C., Morrisey, Edward E., Duncan, Stephen A., Rader, Daniel J.

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Health care worker seromonitoring reveals complex relationships between common coronavirus antibodies and COVID-19 symptom duration von Gouma, Sigrid, Weirick, Madison E., Bolton, Marcus J., Arevalo, Claudia P., Goodwin, Eileen C., Anderson, Elizabeth M., McAllister, Christopher M., Christensen, Shannon R., Dunbar, Debora, Fiore, Danielle, Brock, Amanda, Weaver, JoEllen, Millar, John, DerOhannessian, Stephanie, Frank, Ian, Rader, Daniel J., Wherry, E. John, Hensley, Scott E.

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Dense Genotyping of Candidate Gene Loci Identifies Variants Associated With High-Density Lipoprotein Cholesterol von Edmondson, Andrew C, Braund, Peter S, Stylianou, Ioannis M, Khera, Amit V, Nelson, Christopher P, Wolfe, Megan L, DerOhannessian, Stephanie L, Keating, Brendan J, Qu, Liming, He, Jing, Tobin, Martin D, Tomaszewski, Maciej, Baumert, Jens, Klopp, Norman, Döring, Angela, Thorand, Barbara, Li, Mingyao, Reilly, Muredach P, Koenig, Wolfgang, Samani, Nilesh J, Rader, Daniel J

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Challenges in Interpreting Genetic Reports in Familial Hypercholesterolemia: Variants of Uncertain Significance von Ueda, Masako, MD, Ajufo, Ezim, BM, BCh, Dilzell, Kristen, MS, CGC, Sikora, Tracey, BS, Raper, Anna, MS, CGC, DerOhannessian, Stephanie, MS, Cuchel, Marina, MD, PhD, deGoma, Emil, Rader, Daniel, MD

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An Electronic Health Records Query for Severe Hypercholesterolemia Identifies Individuals With Undiagnosed Clinical and Molecular FH at a Tertiary Academic Centre von Ajufo, Ezim, BM, BCh, Ueda, Masako, MD, Sikora, Tracey, BS, deGoma, Emil, MD, Dilzell, Kristen, MS CGC, Raper, Anna, MS, CGC, DerOhannessian, Stephanie, MS, Hossain, Erik, BS, Cuchel, Marina, MD, PhD, Rader, Daniel, MD

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Familial Chylomicron Syndrome: Importance of Discerning the Rare Among the Common von Ueda, Masako, MD, Burke, Frances, MS, RD, Walters, Laura, BS, Lalic, Dusanka, BS, Sikora, Tracey, BS, Greene, Harley, DerOhannessian, Stephanie, MS, McIntyre, Adam, BSc, deGoma, Emil, MD, Hegele, Robert, MD, Rader, Daniel, MD, Dunbar, Richard, MD

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The Majority of Outpatients With Severe Hypercholesterolemia at an Academic Tertiary Centre Have Not Been Screened for FH von Ajufo, Ezim, BM, BCh, Ueda, Masako, MD, Hossain, Erik, BS, Sikora, Tracey, BS, Damrauer, Scott, MD, deGoma, Emil, MD, Dilzell, Kristen, MS, CGC, DerOhannessian, Stephanie, MS, Cuchel, Marina, MD, PhD, Rader, Daniel, MD

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Translational Studies of Lipoprotein-Associated Phospholipase A2 in Inflammation and Atherosclerosis von Ferguson, Jane F., PhD, Hinkle, Christine C., MS, Mehta, Nehal N., MD, Bagheri, Roshanak, MD, DerOhannessian, Stephanie L., MS, Shah, Rhia, BS, Mucksavage, Megan I., MS, Bradfield, Jonathan P., BS, Hakonarson, Hakon, PhD, Wang, Xuexia, PhD, Master, Stephen R., MD, Rader, Daniel J., MD, Li, Mingyao, PhD, Reilly, Muredach P., MB

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Identification of ADAMTS7 as a novel locus for coronary atherosclerosis and association of ABO with myocardial infarction in the presence of coronary atherosclerosis: two genome-wi... von Reilly, Muredach P, Dr, Li, Mingyao, PhD, He, Jing, PhD, Ferguson, Jane F, PhD, Stylianou, Ioannis M, PhD, Mehta, Nehal N, MD, Burnett, Mary Susan, PhD, Devaney, Joseph M, PhD, Knouff, Christopher W, MD, Thompson, John R, Prof, Horne, Benjamin D, PhD, Stewart, Alexandre FR, PhD, Assimes, Themistocles L, MD, Wild, Philipp S, MD, Allayee, Hooman, PhD, Nitschke, Patrick Linsel, MD, Patel, Riyaz S, MD, Martinelli, Nicola, MD, Girelli, Domenico, Prof, Quyyumi, Arshed A, Prof, Anderson, Jeffrey L, Prof, Erdmann, Jeanette, Prof, Hall, Alistair S, MD, Schunkert, Heribert, Prof, Quertermous, Thomas, Prof, Blankenberg, Stefan, Prof, Hazen, Stanley L, Prof, Roberts, Robert, Prof, Kathiresan, Sekar, MD, Samani, Nilesh J, Prof, Epstein, Stephen E, Prof, Rader, Daniel J, Prof

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CT imaging-derived phenotypes for abdominal muscle and their association with age and sex in a medical biobank von Vu, Phuong T., Chahine, Chantal, Chatterjee, Neil, MacLean, Matthew T., Swago, Sophia, Bhattaru, Abhi, Thompson, Elizabeth W., Ikhlas, Anooshey, Oteng, Edith, Davidson, Lauren, Tran, Richard, Hazim, Mohamad, Raghupathy, Pavan, Verma, Anurag, Duda, Jeffrey, Gee, James, Luks, Valerie, Gershuni, Victoria, Wu, Gary, Rader, Daniel, Sagreiya, Hersh, Witschey, Walter R.

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SARS-CoV-2 infections elicit higher levels of original antigenic sin antibodies compared with SARS-CoV-2 mRNA vaccinations von Anderson, Elizabeth M., Li, Shuk Hang, Awofolaju, Moses, Eilola, Theresa, Goodwin, Eileen, Bolton, Marcus J., Gouma, Sigrid, Manzoni, Tomaz B., Hicks, Philip, Goel, Rishi R., Painter, Mark M., Apostolidis, Sokratis A., Mathew, Divij, Dunbar, Debora, Fiore, Danielle, Brock, Amanda, Weaver, JoEllen, Millar, John S., DerOhannessian, Stephanie, Greenplate, Allison R., Frank, Ian, Rader, Daniel J., Wherry, E. John, Bates, Paul, Hensley, Scott E.

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Clinical correlates of CT imaging-derived phenotypes among lean and overweight patients with hepatic steatosis von Song, Isabel, Thompson, Elizabeth W., Verma, Anurag, MacLean, Matthew T., Duda, Jeffrey, Elahi, Ameena, Tran, Richard, Raghupathy, Pavan, Swago, Sophia, Hazim, Mohamad, Bhattaru, Abhijit, Schneider, Carolin, Vujkovic, Marijana, Torigian, Drew A., Kahn, Charles E., Gee, James C., Borthakur, Arijitt, Kripke, Colleen M., Carson, Christopher C., Carr, Rotonya, Jehangir, Qasim, Ko, Yi-An, Litt, Harold, Rosen, Mark, Mankoff, David A., Schnall, Mitchell D., Shou, Haochang, Chirinos, Julio, Damrauer, Scott M., Serper, Marina, Chen, Jinbo, Rader, Daniel J., Witschey, Walter R. T., Sagreiya, Hersh

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Polygenic risk score-based phenome-wide association for glaucoma and its impact on disease susceptibility in two large biobanks von Yun, Jae-Seung, Jung, Sang-Hyuk, Lee, Su-Nam, Jung, Seung Min, Won, Hong-Hee, Kim, Dokyoon, Choi, Jin A

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Agonist antibody to guanylate cyclase receptor NPR1 regulates vascular tone von Dunn, Michael E., Kithcart, Aaron, Kim, Jee Hae, Ho, Andre Jo-Hao, Franklin, Matthew C., Romero Hernandez, Annabel, de Hoon, Jan, Botermans, Wouter, Meyer, Jonathan, Jin, Ximei, Zhang, Dongqin, Torello, Justin, Jasewicz, Daniel, Kamat, Vishal, Garnova, Elena, Liu, Nina, Rosconi, Michael, Pan, Hao, Karnik, Satyajit, Burczynski, Michael E., Zheng, Wenjun, Rafique, Ashique, Nielsen, Jonas B., De, Tanima, Verweij, Niek, Pandit, Anita, Locke, Adam, Chalasani, Naga, Melander, Olle, Schwantes-An, Tae-Hwi, Baras, Aris, Lotta, Luca A., Musser, Bret J., Mastaitis, Jason, Devalaraja-Narashimha, Kishor B., Rankin, Andrew J., Huang, Tammy, Herman, Gary, Olson, William, Murphy, Andrew J., Yancopoulos, George D., Olenchock, Benjamin A., Morton, Lori

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A Novel APOC2 Missense Mutation Causing Apolipoprotein C-II Deficiency With Severe Triglyceridemia and Pancreatitis von Ueda, Masako, Dunbar, Richard L., Wolska, Anna, Sikora, Tracey U., Escobar, Maria del Rosario, Seliktar, Naomi, deGoma, Emil, DerOhannessian, Stephanie, Morrell, Linda, McIntyre, Adam D., Burke, Frances, Sviridov, Denis, Amar, Marcelo, Shamburek, Robert D., Freeman, Lita, Hegele, Robert A., Remaley, Alan T., Rader, Daniel J.

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Multi-ethnic heterozygote frequencies of cancer susceptibility genes to inform counseling of reproductive risk von Powers, Jacquelyn, Wachtel, Heather, Trujillo, Erica, Desai, Heena, Hausler, Ryan, Conway, Laura, Wubbenhorst, Bradley, Verma, Anurag, Verma, Shefali S., Bradford, Yuki, Brock, Ashlei, DerOhannessian, Stephanie, Dudek, Scott, Dunn, Joseph, Drivas, Theodore, Haubein, Ned, Hu-Sain, Khadijah, Judy, Renae, Kloter, Ashley, Ko, Yi-An, Livingstone, Meghan, Morrel, Linda, Morse, Colleen, Poindexter, Afiya, Risman, Marjorie, Tran, Teo, Vadivieso, Fred, Weaver, JoEllen, Rader, Daniel J., Ritchie, Marylyn D., Feldman, Michael D., Beechert, Christina, Forsythe, Caitlin, Fuller, Erin D., Gu, Zhenhua, Lattari, Michael, Lopez, Alexander, Overton, John D., Padilla, Maria Sotiropoulos, Pradhan, Manasi, Manoochehri, Kia, Schleicher, Thomas D., Widom, Louis, Wolf, Sarah E., Ulloa, Ricardo H., Averitt, Amelia, Banerjee, Nilanjana, Cantor, Michael, Li, Dadong, Malhotra, Sameer, Sharma, Deepika, MHI, Staples, Jeffrey, Bai, Xiaodong, Balasubramanian, Suganthi, Bao, Suying, Boutkov, Boris, Chen, Siying, Eom, Gisu, Habegger, Lukas, Hawes, Alicia, Khalid, Shareef, Krasheninina, Olga, Lanche, Rouel, Mansfield, Adam J., Maxwell, Evan K., Mitra, George, Nafde, Mona, O’Keeffe, Sean, Orelus, Max, B, Panea, Razvan, Polanco, Tommy, Rasool, Ayesha, Reid, Jeffrey G., Salerno, William, Staples, Jeffrey C., Sun, Kathie, Abecasis, Goncalo, Backman, Joshua, Damask, Amy, Dobbyn, Lee, Revez Ferreira, Manuel Allen, Ghosh, Arkopravo, Gillies, Christopher, Gurski, Lauren, Jorgenson, Eric, Kang, Hyun Min, Kessler, Michael, Kosmicki, Jack, Li, Alexander, Lin, Nan, Liu, Daren, Locke, Adam, Marchini, Jonathan, Marcketta, Anthony, Mbatchou, Joelle, Moscati, Arden, Paulding, Charles, Sidore, Carlo

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