Low-complexity regions in Plasmodium falciparum: missing links in the evolution of an extreme genome von Zilversmit, Martine M, Volkman, Sarah K, DePristo, Mark A, Wirth, Dyann F, Awadalla, Philip, Hartl, Daniel L

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A polygenic burden of rare disruptive mutations in schizophrenia von Purcell, Shaun M., Moran, Jennifer L., Fromer, Menachem, Ruderfer, Douglas, Solovieff, Nadia, Roussos, Panos, O’Dushlaine, Colm, Chambert, Kimberly, Bergen, Sarah E., Kähler, Anna, Duncan, Laramie, Stahl, Eli, Genovese, Giulio, Fernández, Esperanza, Collins, Mark O., Komiyama, Noboru H., Choudhary, Jyoti S., Magnusson, Patrik K. E., Banks, Eric, Shakir, Khalid, Garimella, Kiran, Fennell, Tim, DePristo, Mark, Grant, Seth G. N., Haggarty, Stephen J., Gabriel, Stacey, Scolnick, Edward M., Lander, Eric S., Hultman, Christina M., Sullivan, Patrick F., McCarroll, Steven A., Sklar, Pamela

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O.18 Systematic identification of causal mutations in Mendelian disorders using exome sequence data von Lek, M, Clarke, N.F, Waddell, L, Thomas, B, DePristo, M, Daly, M.J, North, K.N, MacArthur, D.G

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Temporal Constraints on the Incorporation of Regulatory Mutants in Evolutionary Pathways von Brown, Kyle M., DePristo, Mark A., Weinreich, Daniel M., Hartl, Daniel L.

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Darwinian Evolution Can Follow Only Very Few Mutational Paths to Fitter Proteins von Weinreich, Daniel M, Delaney, Nigel F, DePristo, Mark A, Hartl, Daniel L

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Human genomic regions with exceptionally high levels of population differentiation identified from 911 whole-genome sequences von Colonna, Vincenza, Ayub, Qasim, Chen, Yuan, Pagani, Luca, Luisi, Pierre, Pybus, Marc, Garrison, Erik, Xue, Yali, Tyler-Smith, Chris, Abecasis, Goncalo R, Auton, Adam, Brooks, Lisa D, DePristo, Mark A, Durbin, Richard M, Handsaker, Robert E, Kang, Hyun Min, Marth, Gabor T, McVean, Gil A

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Simultaneous determination of protein structure and dynamics von Dobson, Christopher M, Vendruscolo, Michele, Lindorff-Larsen, Kresten, Best, Robert B, DePristo, Mark A

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Missense meanderings in sequence space: a biophysical view of protein evolution von DePristo, Mark A, Weinreich, Daniel M, Hartl, Daniel L

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Advantages of fine‐grained side chain conformer libraries von Shetty, Reshma P., de Bakker, Paul I.W., DePristo, Mark A., Blundell, Tom L.

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Heterogeneity and Inaccuracy in Protein Structures Solved by X-Ray Crystallography von DePristo, Mark A, de Bakker, Paul I.W, Blundell, Tom L

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On the abundance, amino acid composition, and evolutionary dynamics of low-complexity regions in proteins von DePristo, Mark A., Zilversmit, Martine M., Hartl, Daniel L.

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The RNA degradosome: life in the fast lane of adaptive molecular evolution von Marcaida, Maria Jose, DePristo, Mark A., Chandran, Vidya, Carpousis, Agamemnon J., Luisi, Ben F.

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Is one solution good enough? von Furnham, Nicholas, Blundell, Tom L, DePristo, Mark A, Terwilliger, Thomas C

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A Low-Frequency Inactivating Akt2 Variant Enriched in the Finnish Population is Associated With Fasting Insulin Levels and Type 2 Diabetes Risk von Fontanillas, P, Rivas, MA, Locke, AE, Isomaa, B, Meitinger, T, Deloukas, P, Stirrups, KE, Owen, KR, Frayling, TM, Levy, JC, Hodgkiss, D, Hattersley, AT, Kuulasmaa, T, Puppala, S, Teslovich, TM, Donnelly, PJ, Ebrahim, SB, Kumar, S, Jia, W, Ma, RC, Sandhu, M, Scott, J, Sladek, R, Tandon, N, Zeggini, E, Watanabe, RM, Koistinen, HA, Collins, FS, Karpe, F, Hansen, T, Kuusisto, J, Hale, DE, Duggirala, R, Hanis, CL, Mohlke, KL, Boehnke, M, Hartl, C, Gloyn, AL, Kumar, A, Ladenvall, C, Scott, LJ, Jula, A, Palotie, A, Jacobs, SB, Wessel, J, Buck, G, Buck, D, Gjesing, AP, Jackson, AU, Jun, G, Justesen, JM, Neville, M, Onofrio, R, Small, KS, Stringham, HM, Trakalo, J, Carneiro, MO, DePristo, M, Grant, G, Poplin, R, Purcell, S, Palmer, ND, Lakka, TA, Langenberg, C, Franks, PW, Ng, MC, Rolandsson, O, Bowden, DW, Mägi, R, Metspalu, A, Narisu, N, Kinnunen, L, Bonnycastle, LL, Pasko, D, Wood, AR, Fadista, J, Pollin, TI, Atzmon, G, Müller-Nurasyid, M, Wu, Y, Illig, T, Meisinger, C, Musani, SK, Taylor, HA, Correa, A, Oksa, H, Scott, WR, Afzal, U, Kooner, JS, Fuchsberger, C, Lee, JY, Huang, J, Melander, O, Below, JE, Lim, WY, Cheng, CY, Chan, E, Tai, ES, Gaulton, KJ, Linneberg, A

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Analysis of protein-coding genetic variation in 60,706 humans von Lek, M, Karczewski, KJ, Minikel, EV, Samocha, KE, Banks, E, Fennell, T, O'Donnell-Luria, AH, Ware, JS, Hill, AJ, Cummings, BB, Tukiainen, T, Birnbaum, DP, Kosmicki, JA, Duncan, LE, Estrada, K, Zhao, F, Zou, J, Pierce-Hoffman, E, Berghout, J, Cooper, DN, Deflaux, N, DePristo, M, Do, R, Flannick, J, Fromer, M, Gauthier, L, Goldstein, J, Gupta, N, Howrigan, D, Kiezun, A, Kurki, MI, Moonshine, AL, Natarajan, P, Orozco, L, Peloso, GM, Poplin, R, Rivas, MA, Ruano-Rubio, V, Rose, SA, Ruderfer, DM, Shakir, K, Stenson, PD, Stevens, C, Thomas, BP, Tiao, G, Tusie-Luna, MT, Weisburd, B, Won, HH, Yu, D, Altshuler, DM, Ardissino, D, Boehnke, M, Danesh, J, Donnelly, S, Elosua, R, Florez, JC, Gabriel, SB, Getz, G, Glatt, SJ, Hultman, CM, Kathiresan, S, Laakso, M, McCarroll, S, McCarthy, MI, McGovern, D, McPherson, R, Neale, BM, Palotie, A, Purcell, SM, Saleheen, D, Scharf, JM, Sklar, P, Sullivan, PF, Tuomilehto, J, Tsuang, MT, Watkins, HC, Wilson, JG, Daly, MJ, MacArthur, DG, Exome Aggregation Consortium

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The genetic architecture of type 2 diabetes von Mihailov, E, Blancher, C, Carneiro, MO, Poplin, R, Hrabé de Angelis, M, Deloukas, P, Onofrio, R, Thorand, B, Hansen, T, Tam, CH, Dupuis, J, Liang, L, O'Rahilly, SP, Watanabe, RM, Bottinger, EP, Cho, YS, Lindgren, CM, Elliott, P, Jablonski, KA, Arya, R, Ma, RC, Hartl, C, Teo, YY, Zeggini, E, DeFronzo, RA, Jackson, AU, Chan, E, Banks, E, Gieger, C, Ingelsson, E, Buck, G, Trakalo, J, Buck, D, Mägi, R, Owen, KR, Morris, AD, Bowden, DW, Atzmon, G, Laakso, M, Duggirala, R, McVean, G, Hanis, CL, Gabriel, S, Meitinger, T, Groop, L, Florez, JC, Altshuler, D, McCarthy, MI, Grarup, N, Stringham, HM, Gamazon, ER, Lee, J, Chen, Y, Below, JE, Huang, J, Pasko, D, Varga, TV, Green, T, Day-Williams, AG, Farook, VS, Fingerlin, T, Hu, C, Kim, BJ, Fowler, SP, Lin, KH, Barzilai, N, Kuusisto, J, Palmer, ND, Balkau, B, Abboud, HE, Griswold, M, Giedraitis, V, Smith, JD, Hale, DE, Lu, Y, Kwak, SH, Kumar, S, Thuillier, D, Musani, SK, Scott, WR, Blackwell, TW, Wong, TY, Bork-Jensen, J, Koistinen, HA, Rayner, NW, Kinnunen, L, Hodgkiss, D, Lyssenko, V, Hollensted, M, Cingolani, P, Jørgensen, T, Ladenvall, C, Justesen, JM, Kriebel, J, Lannfelt, L, Lauritzen, T, Linneberg, A, Locke, AE, Swift, A, Stirrups, K

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Ab initio construction of polypeptide fragments: Efficient generation of accurate, representative ensembles von DePristo, Mark A., de Bakker, Paul I. W., Lovell, Simon C., Blundell, Tom L.

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Ab initio construction of polypeptide fragments: Accuracy of loop decoy discrimination by an all-atom statistical potential and the AMBER force field with the Generalized Born solv... von de Bakker, Paul I. W., DePristo, Mark A., Burke, David F., Blundell, Tom L.

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Erratum: Sequence data and association statistics from 12,940 type 2 diabetes cases and controls von Teslovich, TM, McCarthy, DJ, Rayner, NW, Chines, PS, Lindgren, CM, Hartl, C, Chen, H, Mueller-Nurasyid, M, Below, JE, Stitzel, ML, Pasko, D, Beer, NL, Horikoshi, M, Huh, I, Ikram, MK, Kim, B-J, Kim, Y, Maxwell, TJ, Nagai, Y, Wang, X, Yoon, J, Barzilai, N, Jenkinson, CP, Palmer, ND, Balkau, B, Stancakova, A, Carey, J, Neale, BM, Purcell, S, Zhao, W, Danesh, J, So, WY, Tam, CHT, Afzal, U, Curran, JE, Griswold, M, Khor, C-C, Lehne, B, Thuillier, D, Liu, J, Loh, M, Surdulescu, GL, Herder, C, Bork-Jensen, J, Koistinen, HA, Doney, ASF, Esko, T, Hakaste, L, Milani, L, Qi, L, Rolandsson, O, Stirrups, K, Mihailov, E, Blancher, C, Maguire, J, Poplin, R, Shakir, K, Fennell, T, DePristo, M, Gjesing, AP, Meisinger, C, Peters, A, Huth, C, Rauramaa, R, Bergman, RN, Daly, MJ, Ma, RCW, Pollin, TI, Sandhu, M, Froguel, P, Barroso, I, Ried, JS, DeFronzo, RA, Grallert, H, Metspalu, A, Gieger, C, Im, HK, Illig, T, Buck, G, Buck, D, Owen, KR, Strauch, K, Tuomi, T, Lee, J-Y, Park, T, Donnelly, P, Morris, AD, Laakso, M, McVean, G, Frayling, TM, Meigs, JB, Sladek, R, Lander, ES, Gabriel, S, Mohlke, KL, Groop, L, Scott, LJ, Florez, JC, Boehnke, M, McCarthy, MI

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Crystallographic Refinement by Knowledge-Based Exploration of Complex Energy Landscapes von DePristo, Mark A., de Bakker, Paul I.W., Johnson, Russell J.K., Blundell, Tom L.

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