Tacrolimus-induced cognitive impairment: a case report von Deprez, Valerie, Goeman, Johan, Van Mossevelde, Sara

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Catalytic site inhibition of insulin-degrading enzyme by a small molecule induces glucose intolerance in mice von Deprez-Poulain, Rebecca, Hennuyer, Nathalie, Bosc, Damien, Liang, Wenguang G., Enée, Emmanuelle, Marechal, Xavier, Charton, Julie, Totobenazara, Jane, Berte, Gonzague, Jahklal, Jouda, Verdelet, Tristan, Dumont, Julie, Dassonneville, Sandrine, Woitrain, Eloise, Gauriot, Marion, Paquet, Charlotte, Duplan, Isabelle, Hermant, Paul, Cantrelle, François- Xavier, Sevin, Emmanuel, Culot, Maxime, Landry, Valerie, Herledan, Adrien, Piveteau, Catherine, Lippens, Guy, Leroux, Florence, Tang, Wei-Jen, van Endert, Peter, Staels, Bart, Deprez, Benoit

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NMR Spectroscopy of the Main Protease of SARS‐CoV‐2 and Fragment‐Based Screening Identify Three Protein Hotspots and an Antiviral Fragment von Cantrelle, François‐Xavier, Boll, Emmanuelle, Brier, Lucile, Moschidi, Danai, Belouzard, Sandrine, Landry, Valérie, Leroux, Florence, Dewitte, Frédérique, Landrieu, Isabelle, Dubuisson, Jean, Deprez, Benoit, Charton, Julie, Hanoulle, Xavier

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Structure–activity relationships of imidazole-derived 2-[N-carbamoylmethyl-alkylamino]acetic acids, dual binders of human insulin-degrading enzyme von Charton, Julie, Gauriot, Marion, Totobenazara, Jane, Hennuyer, Nathalie, Dumont, Julie, Bosc, Damien, Marechal, Xavier, Elbakali, Jamal, Herledan, Adrien, Wen, Xiaoan, Ronco, Cyril, Gras-Masse, Helene, Heninot, Antoine, Pottiez, Virginie, Landry, Valerie, Staels, Bart, Liang, Wenguang G., Leroux, Florence, Tang, Wei-Jen, Deprez, Benoit, Deprez-Poulain, Rebecca

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Hypothalamic bile acid-TGR5 signaling protects from obesity von Castellanos-Jankiewicz, Ashley, Guzmán-Quevedo, Omar, Fénelon, Valérie S., Zizzari, Philippe, Quarta, Carmelo, Bellocchio, Luigi, Tailleux, Anne, Charton, Julie, Fernandois, Daniela, Henricsson, Marcus, Piveteau, Catherine, Simon, Vincent, Allard, Camille, Quemener, Sandrine, Guinot, Valentine, Hennuyer, Nathalie, Perino, Alessia, Duveau, Alexia, Maitre, Marlène, Leste-Lasserre, Thierry, Clark, Samantha, Dupuy, Nathalie, Cannich, Astrid, Gonzales, Delphine, Deprez, Benoit, Mithieux, Gilles, Dombrowicz, David, Bäckhed, Fredrik, Prevot, Vincent, Marsicano, Giovanni, Staels, Bart, Schoonjans, Kristina, Cota, Daniela

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Identification of indole-based activators of insulin degrading enzyme von Kraupner, Nicolas, Dinh, Chau Phi, Wen, Xiaoan, Landry, Valérie, Herledan, Adrien, Leroux, Florence, Bosc, Damien, Charton, Julie, Maillard, Clara, Warenghem, Sandrine, Duplan, Isabelle, Piveteau, Catherine, Hennuyer, Nathalie, Staels, Bart, Deprez, Benoit, Deprez-Poulain, Rebecca

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Identification of ebselen as a potent inhibitor of insulin degrading enzyme by a drug repurposing screening von Leroux, Florence, Bosc, Damien, Beghyn, Terence, Hermant, Paul, Warenghem, Sandrine, Landry, Valérie, Pottiez, Virginie, Guillaume, Valentin, Charton, Julie, Herledan, Adrien, Urata, Sarah, Liang, Wenguang, Sheng, Li, Tang, Wei-Jen, Deprez, Benoit, Deprez-Poulain, Rebecca

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STXBP1 encephalopathy: A neurodevelopmental disorder including epilepsy von Stamberger, Hannah, Nikanorova, Marina, Willemsen, Marjolein H, Accorsi, Patrizia, Angriman, Marco, Baier, Hartmut, Benkel-Herrenbrueck, Ira, Benoit, Valérie, Budetta, Mauro, Caliebe, Almuth, Cantalupo, Gaetano, Capovilla, Giuseppe, Casara, Gianluca, Courage, Carolina, Deprez, Marie, Destrée, Anne, Dilena, Robertino, Erasmus, Corrie E, Fannemel, Madeleine, Fjær, Roar, Giordano, Lucio, Helbig, Katherine L, Heyne, Henrike O, Klepper, Joerg, Kluger, Gerhard J, Lederer, Damien, Lodi, Monica, Maier, Oliver, Merkenschlager, Andreas, Michelberger, Nina, Minetti, Carlo, Muhle, Hiltrud, Phalin, Judith, Ramsey, Keri, Romeo, Antonino, Schallner, Jens, Schanze, Ina, Shinawi, Marwan, Sleegers, Kristel, Sterbova, Katalin, Syrbe, Steffen, Traverso, Monica, Tzschach, Andreas, Uldall, Peter, Van Coster, Rudy, Verhelst, Helene, Viri, Maurizio, Winter, Susan, Wolff, Markus, Zenker, Martin, Zoccante, Leonardo, De Jonghe, Peter, Helbig, Ingo, Striano, Pasquale, Lemke, Johannes R, Møller, Rikke S, Weckhuysen, Sarah

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A second case of Okamoto syndrome caused by HNRNPK mutation von Maystadt, Isabelle, Deprez, Marie, Moortgat, Stéphanie, Benoît, Valérie, Karadurmus, Deniz

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Novel dithiocarbamates selectively inhibit 3CL protease of SARS-CoV-2 and other coronaviruses von Brier, Lucile, Hassan, Haitham, Hanoulle, Xavier, Landry, Valerie, Moschidi, Danai, Desmarets, Lowiese, Rouillé, Yves, Dumont, Julie, Herledan, Adrien, Warenghem, Sandrine, Piveteau, Catherine, Carré, Paul, Ikherbane, Sarah, Cantrelle, François-Xavier, Dupré, Elian, Dubuisson, Jean, Belouzard, Sandrine, Leroux, Florence, Deprez, Benoit, Charton, Julie

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N-acylbenzimidazoles as selective Acylators of the catalytic cystein of the coronavirus 3CL protease von Chaibi, Fatima-Zahra, Brier, Lucile, Carré, Paul, Landry, Valérie, Desmarets, Lowiese, Tarricone, Audrey, Cantrelle, François-Xavier, Moschidi, Danai, Herledan, Adrien, Biela, Alexandre, Bourgeois, Fanny, Ribes, Chloé, Ikherbane, Sarah, Malessan, Mathilde, Dubuisson, Jean, Belouzard, Sandrine, Hanoulle, Xavier, Leroux, Florence, Deprez, Benoit, Charton, Julie

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Imidazole-derived 2-[N-carbamoylmethyl-alkylamino]acetic acids, substrate-dependent modulators of insulin-degrading enzyme in amyloid-β hydrolysis von Charton, Julie, Gauriot, Marion, Guo, Qing, Hennuyer, Nathalie, Marechal, Xavier, Dumont, Julie, Hamdane, Malika, Pottiez, Virginie, Landry, Valerie, Sperandio, Olivier, Flipo, Marion, Buee, Luc, Staels, Bart, Leroux, Florence, Tang, Wei-Jen, Deprez, Benoit, Deprez-Poulain, Rebecca

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Intrinsic Antibacterial Activity of Nanoparticles Made of β‑Cyclodextrins Potentiates Their Effect as Drug Nanocarriers against Tuberculosis von Machelart, Arnaud, Salzano, Giuseppina, Li, Xue, Demars, Aurore, Debrie, Anne-Sophie, Menendez-Miranda, Mario, Pancani, Elisabetta, Jouny, Samuel, Hoffmann, Eik, Deboosere, Nathalie, Belhaouane, Imène, Rouanet, Carine, Simar, Sophie, Talahari, Smaïl, Giannini, Valerie, Villemagne, Baptiste, Flipo, Marion, Brosch, Roland, Nesslany, Fabrice, Deprez, Benoit, Muraille, Eric, Locht, Camille, Baulard, Alain R, Willand, Nicolas, Majlessi, Laleh, Gref, Ruxandra, Brodin, Priscille

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Eight further individuals with intellectual disability and epilepsy carrying bi-allelic CNTNAP2 aberrations allow delineation of the mutational and phenotypic spectrum von Smogavec, Mateja, Cleall, Alison, Hoyer, Juliane, Lederer, Damien, Nassogne, Marie-Cécile, Palmer, Elizabeth E, Deprez, Marie, Benoit, Valérie, Maystadt, Isabelle, Noakes, Charlotte, Leal, Alejandro, Shaw, Marie, Gecz, Jozef, Raymond, Lucy, Reis, André, Shears, Deborah, Brockmann, Knut, Zweier, Christiane

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Assessment of Digital PCR as a Primary Reference Measurement Procedure to Support Advances in Precision Medicine von Whale, Alexandra S, Jones, Gerwyn M, Pavšič, Jernej, Dreo, Tanja, Redshaw, Nicholas, Akyürek, Sema, Akgöz, Müslüm, Divieto, Carla, Sassi, Maria Paola, He, Hua-Jun, Cole, Kenneth D, Bae, Young-Kyung, Park, Sang-Ryoul, Deprez, Liesbet, Corbisier, Philippe, Garrigou, Sonia, Taly, Valérie, Larios, Raquel, Cowen, Simon, O'Sullivan, Denise M, Bushell, Claire A, Goenaga-Infante, Heidi, Foy, Carole A, Woolford, Alison J, Parkes, Helen, Huggett, Jim F, Devonshire, Alison S

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Characteristics and progression of patients with frontotemporal dementia in a regional memory clinic network von Leroy, Mélanie, Bertoux, Maxime, Skrobala, Emilie, Mode, Elisa, Adnet-Bonte, Catherine, Le Ber, Isabelle, Bombois, Stéphanie, Cassagnaud, Pascaline, Chen, Yaohua, Deramecourt, Vincent, Lebert, Florence, Mackowiak, Marie Anne, Sillaire, Adeline Rollin, Wathelet, Marielle, Pasquier, Florence, Lebouvier, Thibaud

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Catalytic site inhibition of insulin-degrading enzyme by a small molecule induces glucose intolerance in mice von Deprez-Poulain, Rebecca, Hennuyer, Nathalie, Bosc, Damien, Liang, Wenguang G., Enée, Emmanuelle, Marechal, Xavier, Charton, Julie, Totobenazara, Jane, Berte, Gonzague, Jahklal, Jouda, Verdelet, Tristan, Dumont, Julie, Dassonneville, Sandrine, Woitrain, Eloise, Gauriot, Marion, Paquet, Charlotte, Duplan, Isabelle, Hermant, Paul, Cantrelle, François- Xavier, Sevin, Emmanuel, Culot, Maxime, Landry, Valerie, Herledan, Adrien, Piveteau, Catherine, Lippens, Guy, Leroux, Florence, Tang, Wei-Jen, van Endert, Peter, Staels, Bart, Deprez, Benoit

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New non-hydroxamic ADAMTS-5 inhibitors based on the 1,2,4-triazole-3-thiol scaffold von Maingot, Lucie, Leroux, Florence, Landry, Valérie, Dumont, Julie, Nagase, Hideaki, Villoutreix, Bruno, Sperandio, Olivier, Deprez-Poulain, Rebecca, Deprez, Benoit

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NF-κB Activation and Severity of Gastritis in Helicobacter pylori-Infected Children and Adults von Bontems, Patrick, Aksoy, Ezra, Burette, Alain, Segers, Valérie, Deprez, Carine, Mascart, Françoise, Cadranel, Samy

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Human glioblastoma‐initiating cells invade specifically the subventricular zones and olfactory bulbs of mice after striatal injection von Kroonen, Jérôme, Nassen, Jessica, Boulanger, Yves‐Gautier, Provenzano, Fabian, Capraro, Valérie, Bours, Vincent, Martin, Didier, Deprez, Manuel, Robe, Pierre, Rogister, Bernard

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