Peroxynitrite nitration of Tyr 56 in Hsp90 induces PC12 cell death through P2X7R-dependent PTEN activation von Jandy, Megan, Noor, Asra, Nelson, Pascal, Dennys, Cassandra N., Karabinas, Isabella M., Pestoni, Jeanine C., Singh, Gautam D., Luc, Lam, Devyldere, Rachel, Perdomo, Nathalie, Mitchell, Catherine E., Adams, Levi, Fuse, Marisa A., Mendoza, Francine A., Marean-Reardon, Carrie L., Mehl, Ryan A., Estevez, Alvaro G., Franco, Maria Clara

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Neurotoxic Astrocytes Directly Converted from Sporadic and Familial ALS Patient Fibroblasts Reveal Signature Diversities and miR-146a Theragnostic Potential in Specific Subtypes von Gomes, Cátia, Sequeira, Catarina, Likhite, Shibi, Dennys, Cassandra N, Kolb, Stephen J, Shaw, Pamela J, Vaz, Ana R, Kaspar, Brian K, Meyer, Kathrin, Brites, Dora

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NMR-Guided Design of Potent and Selective EphA4 Agonistic Ligands von Baggio, Carlo, Kulinich, Anna, Dennys, Cassandra N, Rodrigo, Rochelle, Meyer, Kathrin, Ethell, Iryna, Pellecchia, Maurizio

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PolyGA targets the ER stress-adaptive response by impairing GRP75 function at the MAM in C9ORF72-ALS/FTD von Pilotto, Federica, Schmitz, Alexander, Maharjan, Niran, Diab, Rim, Odriozola, Adolfo, Tripathi, Priyanka, Yamoah, Alfred, Scheidegger, Olivier, Oestmann, Angelina, Dennys, Cassandra N., Sinha Ray, Shrestha, Rodrigo, Rochelle, Kolb, Stephen, Aronica, Eleonora, Di Santo, Stefano, Widmer, Hans Rudolf, Charlet-Berguerand, Nicolas, Selvaraj, Bhuvaneish T, Chandran, Siddharthan, Meyer, Kathrin, Zuber, Benoît, Goswami, Anand, Weis, Joachim, Saxena, Smita

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CuATSM effectively ameliorates ALS patient astrocyte‐mediated motor neuron toxicity in human in vitro models of amyotrophic lateral sclerosis von Dennys, Cassandra N., Roussel, Florence, Rodrigo, Rochelle, Zhang, Xiaojin, Sierra Delgado, Andrea, Hartlaub, Annalisa, Saelim‐Ector, Asya, Ray, Will, Heintzman, Sarah, Fox, Ashley, Kolb, Stephen J., Beckman, Joseph, Franco, Maria Clara, Meyer, Kathrin

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MeCP2 gene therapy ameliorates disease phenotype in mouse model for Pitt Hopkins syndrome von Dennys, Cassandra N., Vermudez, Sheryl Anne D., Deacon, Robert J.M., Sierra-Delgado, J. Andrea, Rich, Kelly, Zhang, Xiaojin, Buch, Aditi, Weiss, Kelly, Moxley, Yuta, Rajpal, Hemangi, Espinoza, Francisca D., Powers, Samantha, Ávila, Ariel S., Gogliotti, Rocco G., Cogram, Patricia, Niswender, Colleen M., Meyer, Kathrin C.

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In vitro Modeling for Neurological Diseases using Direct Conversion from Fibroblasts to Neuronal Progenitor Cells and Differentiation into Astrocytes von Dennys, Cassandra N., Sierra-Delgado, Julieth A., Ray, Shrestha Sinha, Hartlaub, Annalisa M., Roussel, Florence S., Rodriguez, Yacidzohara, Meyer, Kathrin

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Nitration of Hsp90 on Tyrosine 33 Regulates Mitochondrial Metabolism von Franco, Maria C., Ricart, Karina C., Gonzalez, Analía S., Dennys, Cassandra N., Nelson, Pascal A., Janes, Michael S., Mehl, Ryan A., Landar, Aimee, Estévez, Alvaro G.

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Chronic inhibitory effect of riluzole on trophic factor production von Dennys, Cassandra N., Armstrong, JeNay, Levy, Mark, Byun, Youn Jung, Ramdial, Kristina R., Bott, Marga, Rossi, Fabian H., Fernández-Valle, Cristina, Franco, Maria Clara, Estevez, Alvaro G.

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Gene Therapy Corrects Brain and Behavioral Pathologies in CLN6-Batten Disease von Cain, Jacob T., Likhite, Shibi, White, Katherine A., Timm, Derek J., Davis, Samantha S., Johnson, Tyler B., Dennys-Rivers, Cassandra N., Rinaldi, Federica, Motti, Dario, Corcoran, Sarah, Morales, Pablo, Pierson, Christopher, Hughes, Stephanie M., Lee, Stella Y., Kaspar, Brian K., Meyer, Kathrin, Weimer, Jill M.

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Temporal patterns of tyrosine nitration in embryo heart development von Viera, Liliana, Radmilovich, Milka, Vargas, Marcelo R., Dennys, Cassandra N., Wilson, Landon, Barnes, Stephen, Franco, Maria Clara, Beckman, Joseph S., Estévez, Alvaro G.

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Highlight article: Ligand-independent activation of the P2X7 receptor by Hsp90 inhibition stimulates motor neuron apoptosis von Strayer, Amy L, Dennys-Rivers, Cassandra N, Ricart, Karina C, Bae, Narae, Beckman, Joseph S, Franco, Maria Clara, Estevez, Alvaro G

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In vitro Modeling for Neurological Diseases using Direct Conversion from Fibroblasts to Neuronal Progenitor Cells and Differentiation into Astrocytes von Dennys, Cassandra N., Sierra-Delgado, Julieth A., Ray, Shrestha Sinha, Hartlaub, Annalisa M., Roussel, Florence S., Rodriguez, Yacidzohara, Meyer, Kathrin

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294 - Site-Specific Nitrated Hsp90 Is a Target for Drug Development in Cancer von Franco, Maria Clara, Ricart, Karina C., Gonzalez, Analia S., Dennys, Cassandra N., Nelson, Pascal A., Janes, Michael S., Mehl, Ryan A., Landar, Aimee, Estévez, Alvaro G.

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Site-Specific Nitrated Hsp90 Is a Target for Drug Development in Cancer von Franco, Maria Clara, Ricart, Karina C., Gonzalez, Analia S., Dennys, Cassandra N., Nelson, Pascal A., Janes, Michael S., Mehl, Ryan A., Landar, Aimee, Estévez, Alvaro G.

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Ligand-independent activation of the P2X7 receptor by Hsp90 inhibition stimulates motor neuron apoptosis von Strayer, Amy L, Dennys-Rivers, Cassandra N, Ricart, Karina C, Bae, Narae, Beckman, Joseph S, Franco, Maria Clara, Estevez, Alvaro G

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