The human hepatoma HepaRG cells: A highly differentiated model for studies of liver metabolism and toxicity of xenobiotics von Guillouzo, André, Corlu, Anne, Aninat, Caroline, Glaise, Denise, Morel, Fabrice, Guguen-Guillouzo, Christiane

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Inflammatory cytokines promote the retrodifferentiation of tumor‐derived hepatocyte‐like cells to progenitor cells von Dubois‐Pot‐Schneider, Hélène, Fekir, Karim, Coulouarn, Cédric, Glaise, Denise, Aninat, Caroline, Jarnouen, Kathleen, Le Guével, Rémy, Kubo, Takashi, Ishida, Seiichi, Morel, Fabrice, Corlu, Anne

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Infection of a Human Hepatoma Cell Line by Hepatitis B Virus von Gripon, Philippe, Rumin, Sylvie, Urban, Stephan, Le Seyec, Jacques, Glaise, Denise, Cannie, Isabelle, Guyomard, Claire, Lucas, Josette, Trepo, Christian, Guguen-Guillouzo, Christiane

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Transdifferentiation of hepatocyte‐like cells from the human hepatoma HepaRG cell line through bipotent progenitor von Cerec, Virginie, Glaise, Denise, Garnier, Delphine, Morosan, Serban, Turlin, Bruno, Drenou, Bernard, Gripon, Philippe, Kremsdorf, Dina, Guguen‐Guillouzo, Christiane, Corlu, Anne

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Transcriptional and Epigenetic Consequences of DMSO Treatment on HepaRG Cells von Dubois-Pot-Schneider, Hélène, Aninat, Caroline, Kattler, Kathrin, Fekir, Karim, Jarnouen, Kathleen, Cerec, Virginie, Glaise, Denise, Salhab, Abdulrahman, Gasparoni, Gilles, Takashi, Kubo, Ishida, Seiichi, Walter, Jörn, Corlu, Anne

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TET-Catalyzed 5-Hydroxymethylation Precedes HNF4A Promoter Choice during Differentiation of Bipotent Liver Progenitors von Ancey, Pierre-Benoit, Ecsedi, Szilvia, Lambert, Marie-Pierre, Talukdar, Fazlur Rahman, Cros, Marie-Pierre, Glaise, Denise, Narvaez, Diana Maria, Chauvet, Veronique, Herceg, Zdenko, Corlu, Anne, Hernandez-Vargas, Hector

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Functional expression of sinusoidal and canalicular hepatic drug transporters in the differentiated human hepatoma HepaRG cell line von Le Vee, Marc, Jigorel, Emilie, Glaise, Denise, Gripon, Philippe, Guguen-Guillouzo, Christiane, Fardel, Olivier

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The Mitogen-Activated Protein Kinase Kinase/Extracellular Signal-Regulated Kinase Cascade Activation Is a Key Signalling Pathway Involved in the Regulation of G1 Phase Progression... von Talarmin, Hélène, Rescan, Claude, Cariou, Sandrine, Glaise, Denise, Zanninelli, Giuliana, Bilodeau, Marc, Loyer, Pascal, Guguen-Guillouzo, Christiane, Baffet, Georges

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Liver Protection from Apoptosis Requires Both Blockage of Initiator Caspase Activities and Inhibition of ASK1/JNK Pathway via Glutathione S-Transferase Regulation von Gilot, David, Loyer, Pascal, Corlu, Anne, Glaise, Denise, Lagadic-Gossmann, Dominique, Atfi, Azeddine, Morel, Fabrice, Ichijo, Hidenori, Guguen-Guillouzo, Christiane

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Regulation and role of p21 and p27 cyclin-dependent kinase inhibitors during hepatocyte differentiation and growth von Ilyin, Gennady P, Glaise, Denise, Gilot, David, Baffet, Georges, Guguen-Guillouzo, Christiane

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Hepatocyte―Stellate Cell Cross-Talk in the Liver Engenders a Permissive Inflammatory Microenvironment That Drives Progression in Hepatocellular Carcinoma von COULOUARN, Cédric, CORLU, Anne, GLAISE, Denise, GUENON, Isabelle, THORGEIRSSON, Snorri S, CLEMENT, Bruno

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Retrodifferentiation of Human Tumor Hepatocytes to Stem Cells Leads to Metabolic Reprogramming and Chemoresistance von Fekir, Karim, Dubois-Pot-Schneider, Hélène, Désert, Romain, Daniel, Yoann, Glaise, Denise, Rauch, Claudine, Morel, Fabrice, Fromenty, Bernard, Musso, Orlando, Cabillic, Florian, Corlu, Anne

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Upregulation of the tumor suppressor gene menin in hepatocellular carcinomas and its significance in fibrogenesis von Zindy, Pierre J., L'Helgoualc'h, Annie, Bonnier, Dominique, Le Béchec, Antony, Bourd‐Boitin, Katia, Zhang, Chang Xian, Musso, Orlando, Glaise, Denise, Bérangère Troadec, Marie, Loréal, Olivier, Turlin, Bruno, Léger, Jean, Clément, Bruno, Théret, Nathalie

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Evaluation of genotoxicity using automated detection of γH2AX in metabolically competent HepaRG cells von Quesnot, Nicolas, Rondel, Karine, Audebert, Marc, Martinais, Sophie, Glaise, Denise, Morel, Fabrice, Loyer, Pascal, Robin, Marie-Anne

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A Minimal Subset of Seven Genes Associated with Tumor Hepatocyte Differentiation Predicts a Poor Prognosis in Human Hepatocellular Carcinoma von Desoteux, Matthis, Louis, Corentin, Bévant, Kevin, Glaise, Denise, Coulouarn, Cédric

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A new subfamily of structurally related human F-box proteins von Ilyin, Gennady P, Sérandour, Anne-Laure, Pigeon, Christelle, Rialland, Mickael, Glaise, Denise, Guguen-Guillouzo, Christiane

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Endotoxin regulates matrix genes increasing reactive oxygen species generation by intercellular communication between palmitate‐treated hepatocyte and stellate cell von Dornas, Waleska, Glaise, Denise, Bodin, Aude, Sharanek, Ahmad, Burban, Audrey, Le Guillou, Dounia, Robert, Sacha, Dutertre, Stephanie, Aninat, Caroline, Corlu, Anne, Lagente, Vincent

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Automated detection of hepatotoxic compounds in human hepatocytes using HepaRG cells and image-based analysis of mitochondrial dysfunction with JC-1 dye von Pernelle, K., Le Guevel, R., Glaise, D., Stasio, C. Gaucher-Di, Le Charpentier, T., Bouaita, B., Corlu, A., Guguen-Guillouzo, C.

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Highly Efficient SiRNA and Gene Transfer into Hepatocyte-Like HepaRG Cells and Primary Human Hepatocytes: New Means for Drug Metabolism and Toxicity Studies von Laurent, Véronique, Glaise, Denise, Nübel, Tobias, Gilot, David, Corlu, Anne, Loyer, Pascal

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The application of 3D micropatterning of agarose substrate for cell culture and in situ comet assays von Mercey, Emilie, Obeïd, Patricia, Glaise, Denise, Calvo-Muñoz, Maria-Luisa, Guguen-Guillouzo, Christiane, Fouqué, Brigitte

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