Unraveling Triple-Negative Breast Cancer Tumor Microenvironment Heterogeneity: Towards an Optimized Treatment Approach von Bareche, Yacine, Buisseret, Laurence, Gruosso, Tina, Girard, Edwina, Venet, David, Dupont, Floriane, Desmedt, Christine, Larsimont, Denis, Park, Morag, Rothé, Françoise, Stagg, John, Sotiriou, Christos

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Subclonal diversification of primary breast cancer revealed by multiregion sequencing von Yates, Lucy R, Gerstung, Moritz, Knappskog, Stian, Desmedt, Christine, Gundem, Gunes, Van Loo, Peter, Aas, Turid, Alexandrov, Ludmil B, Larsimont, Denis, Davies, Helen, Li, Yilong, Ju, Young Seok, Ramakrishna, Manasa, Haugland, Hans Kristian, Lilleng, Peer Kaare, Nik-Zainal, Serena, McLaren, Stuart, Butler, Adam, Martin, Sancha, Glodzik, Dominic, Menzies, Andrew, Raine, Keiran, Hinton, Jonathan, Jones, David, Mudie, Laura J, Jiang, Bing, Vincent, Delphine, Greene-Colozzi, April, Adnet, Pierre-Yves, Fatima, Aquila, Maetens, Marion, Ignatiadis, Michail, Stratton, Michael R, Sotiriou, Christos, Richardson, Andrea L, Lønning, Per Eystein, Wedge, David C, Campbell, Peter J

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Biological Processes Associated with Breast Cancer Clinical Outcome Depend on the Molecular Subtypes von DESMEDT, Christine, HAIBE-KAINS, Benjamin, WIRAPATI, Pratyaksha, BUYSE, Marc, LARSIMONT, Denis, BONTEMPI, Gianluca, DELORENZI, Mauro, PICCART, Martine, SOTIRIOU, Christos

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Genomic Characterization of Primary Invasive Lobular Breast Cancer von Desmedt, Christine, Zoppoli, Gabriele, Gundem, Gunes, Pruneri, Giancarlo, Larsimont, Denis, Fornili, Marco, Fumagalli, Debora, Brown, David, Rothé, Françoise, Vincent, Delphine, Kheddoumi, Naima, Rouas, Ghizlane, Majjaj, Samira, Brohée, Sylvain, Van Loo, Peter, Maisonneuve, Patrick, Salgado, Roberto, Van Brussel, Thomas, Lambrechts, Diether, Bose, Ron, Metzger, Otto, Galant, Christine, Bertucci, François, Piccart-Gebhart, Martine, Viale, Giuseppe, Biganzoli, Elia, Campbell, Peter J, Sotiriou, Christos

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Tumor infiltrating B-cells signal functional humoral immune responses in breast cancer von Garaud, Soizic, Buisseret, Laurence, Solinas, Cinzia, Gu-Trantien, Chunyan, de Wind, Alexandre, Van den Eynden, Gert, Naveaux, Celine, Lodewyckx, Jean-Nicolas, Boisson, Anaïs, Duvillier, Hugues, Craciun, Ligia, Ameye, Lieveke, Veys, Isabelle, Paesmans, Marianne, Larsimont, Denis, Piccart-Gebhart, Martine, Willard-Gallo, Karen

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The genomic landscape of carcinomas with mucinous differentiation von Nguyen, Bastien, Sanchez-Vega, Francisco, Fong, Christopher J., Chatila, Walid K., Boroujeni, Amir Momeni, Pareja, Fresia, Weigelt, Britta, Sotiriou, Christos, Larsimont, Denis, Reis-Filho, Jorge S., Desmedt, Christine, Schultz, Nikolaus

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Phylogenetic analysis of metastatic progression in breast cancer using somatic mutations and copy number aberrations von Brown, David, Smeets, Dominiek, Székely, Borbála, Larsimont, Denis, Szász, A. Marcell, Adnet, Pierre-Yves, Rothé, Françoise, Rouas, Ghizlane, Nagy, Zsófia I., Faragó, Zsófia, Tőkés, Anna-Mária, Dank, Magdolna, Szentmártoni, Gyöngyvér, Udvarhelyi, Nóra, Zoppoli, Gabriele, Pusztai, Lajos, Piccart, Martine, Kulka, Janina, Lambrechts, Diether, Sotiriou, Christos, Desmedt, Christine

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HER2 and TOP2A as predictive markers for anthracycline-containing chemotherapy regimens as adjuvant treatment of breast cancer: a meta-analysis of individual patient data von Leo, Angelo Di, Dr, Desmedt, Christine, PhD, Bartlett, John M S, Prof, Piette, Fanny, PhD, Ejlertsen, Bent, MD, Pritchard, Kathleen I, Prof, Larsimont, Denis, MD, Poole, Christopher, Prof, Isola, Jorma, Prof, Earl, Helena, Prof, Mouridsen, Henning, MD, O'Malley, Frances P, MD, Cardoso, Fatima, MD, Tanner, Minna, MD, Munro, Alison, PhD, Twelves, Chris J, Prof, Sotiriou, Christos, MD, Shepherd, Lois, MD, Cameron, David, Prof, Piccart, Martine J, Prof, Buyse, Marc, PhD

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Principles Governing A-to-I RNA Editing in the Breast Cancer Transcriptome von Fumagalli, Debora, Gacquer, David, Rothé, Françoise, Lefort, Anne, Libert, Frederick, Brown, David, Kheddoumi, Naima, Shlien, Adam, Konopka, Tomasz, Salgado, Roberto, Larsimont, Denis, Polyak, Kornelia, Willard-Gallo, Karen, Desmedt, Christine, Piccart, Martine, Abramowicz, Marc, Campbell, Peter J., Sotiriou, Christos, Detours, Vincent

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Reliability of tumor-infiltrating lymphocyte and tertiary lymphoid structure assessment in human breast cancer von Buisseret, Laurence, Desmedt, Christine, Garaud, Soizic, Fornili, Marco, Wang, Xiaoxiao, Van den Eyden, Gert, de Wind, Alexandre, Duquenne, Sebastien, Boisson, Anais, Naveaux, Celine, Rothé, Francoise, Rorive, Sandrine, Decaestecker, Christine, Larsimont, Denis, Piccart-Gebhart, Martine, Biganzoli, Elia, Sotiriou, Christos, Willard-Gallo, Karen

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Tumor-infiltrating lymphocyte composition, organization and PD-1/ PD-L1 expression are linked in breast cancer von Buisseret, Laurence, Garaud, Soizic, de Wind, Alexandre, Van den Eynden, Gert, Boisson, Anais, Solinas, Cinzia, Gu-Trantien, Chunyan, Naveaux, Céline, Lodewyckx, Jean-Nicolas, Duvillier, Hugues, Craciun, Ligia, Veys, Isabelle, Larsimont, Denis, Piccart-Gebhart, Martine, Stagg, John, Sotiriou, Christos, Willard-Gallo, Karen

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Antigen Specificity and Clinical Significance of IgG and IgA Autoantibodies Produced in situ by Tumor-Infiltrating B Cells in Breast Cancer von Garaud, Soizic, Zayakin, Pawel, Buisseret, Laurence, Rulle, Undine, Silina, Karina, de Wind, Alexandre, Van den Eyden, Gert, Larsimont, Denis, Willard-Gallo, Karen, Linē, Aija

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Inhibition of RANK signaling in breast cancer induces an anti-tumor immune response orchestrated by CD8+ T cells von Gómez-Aleza, Clara, Nguyen, Bastien, Yoldi, Guillermo, Ciscar, Marina, Barranco, Alexandra, Hernández-Jiménez, Enrique, Maetens, Marion, Salgado, Roberto, Zafeiroglou, Maria, Pellegrini, Pasquale, Venet, David, Garaud, Soizic, Trinidad, Eva M., Benítez, Sandra, Vuylsteke, Peter, Polastro, Laura, Wildiers, Hans, Simon, Philippe, Lindeman, Geoffrey, Larsimont, Denis, Van den Eynden, Gert, Velghe, Chloé, Rothé, Françoise, Willard-Gallo, Karen, Michiels, Stefan, Muñoz, Purificación, Walzer, Thierry, Planelles, Lourdes, Penninger, Josef, Azim, Hatem A., Loi, Sherene, Piccart, Martine, Sotiriou, Christos, González-Suárez, Eva

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Gene Expression Profiling in Breast Cancer: Understanding the Molecular Basis of Histologic Grade To Improve Prognosis von Sotiriou, Christos, Wirapati, Pratyaksha, Loi, Sherene, Harris, Adrian, Fox, Steve, Smeds, Johanna, Nordgren, Hans, Farmer, Pierre, Praz, Viviane, Haibe-Kains, Benjamin, Desmedt, Christine, Larsimont, Denis, Cardoso, Fatima, Peterse, Hans, Nuyten, Dimitry, Buyse, Marc, Van de Vijver, Marc J., Bergh, Jonas, Piccart, Martine, Delorenzi, Mauro

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Definition of Clinically Distinct Molecular Subtypes in Estrogen Receptor–Positive Breast Carcinomas Through Genomic Grade von LOI, Sherene, HAIBE-KAINS, Benjamin, KLIJN, Jan G. M, LARSIMONT, Denis, BUYSE, Marc, BONTEMPI, Gianluca, DELORENZI, Mauro, PICCART, Martine J, SOTIRIOU, Christos, DESMEDT, Christine, LALLEMAND, Francoise, TUTT, Andrew M, GILLET, Cheryl, ELLIS, Paul, HARRIS, Adrian, BERGH, Jonas, FOEKENS, John A

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High Risk of Recurrence for Patients With Breast Cancer Who Have Human Epidermal Growth Factor Receptor 2–Positive, Node-Negative Tumors 1 cm or Smaller von GONZALEZ-ANGULO, Ana M, LITTON, Jennifer K, LARSIMONT, Denis, FEOLI, Francesco, STRANZL, Heidi, BUCHHOLZ, Thomas A, VALERO, Vicente, THERIAULT, Richard, PICCART-GEBHART, Martine, RAVDIN, Peter M, BERRY, Donald A, HORTOBAGYI, Gabriel N, BROGLIO, Kristine R, MERIC-BERNSTAM, Funda, RAKKHIT, Ronjay, CARDOSO, Fatima, PEINTINGER, Florentia, HANRAHAN, Emer O, SAHIN, Aysegul, GURAY, Merih

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Reprogramming of Energy Metabolism: Increased Expression and Roles of Pyruvate Carboxylase in Papillary Thyroid Cancer von Strickaert, Aurélie, Corbet, Cyril, Spinette, Selim-Alex, Craciun, Ligia, Dom, Geneviève, Andry, Guy, Larsimont, Denis, Wattiez, Ruddy, Dumont, Jacques E., Feron, Olivier, Maenhaut, Carine

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Immune Checkpoint Molecules on Tumor-Infiltrating Lymphocytes and Their Association with Tertiary Lymphoid Structures in Human Breast Cancer von Solinas, Cinzia, Garaud, Soizic, De Silva, Pushpamali, Boisson, Anaïs, Van den Eynden, Gert, de Wind, Alexandre, Risso, Paolo, Rodrigues Vitória, Joel, Richard, François, Migliori, Edoardo, Noël, Grégory, Duvillier, Hugues, Craciun, Ligia, Veys, Isabelle, Awada, Ahmad, Detours, Vincent, Larsimont, Denis, Piccart-Gebhart, Martine, Willard-Gallo, Karen

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PIK3CA mutations associated with gene signature of low mTORC1 signaling and better outcomes in estrogen receptor—positive breast cancer von Loi, Sherene, Haibe-Kains, Benjamin, Majjaj, Samira, Lallemand, Francoise, Durbecq, Virginie, Larsimont, Denis, Gonzalez-Angulo, Ana M., Pusztai, Lajos, Symmans, W. Fraser, Bardelli, Alberto, Ellis, Paul, Tutt, Andrew N. J., Gillett, Cheryl E., Hennessy, Bryan T., Mills, Gordon B., Phillips, Wayne A., Piccart, Martine J., Speed, Terence P., McArthur, Grant A., Sotiriou, Christos, Brugge, Joan S.

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Spatial transcriptomics reveals substantial heterogeneity in triple-negative breast cancer with potential clinical implications von Wang, Xiaoxiao, Venet, David, Lifrange, Frédéric, Larsimont, Denis, Rediti, Mattia, Stenbeck, Linnea, Dupont, Floriane, Rouas, Ghizlane, Garcia, Andrea Joaquin, Craciun, Ligia, Buisseret, Laurence, Ignatiadis, Michail, Carausu, Marcela, Bhalla, Nayanika, Masarapu, Yuvarani, Villacampa, Eva Gracia, Franzén, Lovisa, Saarenpää, Sami, Kvastad, Linda, Thrane, Kim, Lundeberg, Joakim, Rothé, Françoise, Sotiriou, Christos

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