Arginine side chain interactions and the role of arginine as a gating charge carrier in voltage sensitive ion channels von Armstrong, Craig T., Mason, Philip E., Anderson, J. L. Ross, Dempsey, Christopher E.

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An Update on the Structure of hERG von Butler, Andrew, Helliwell, Matthew V., Zhang, Yihong, Hancox, Jules C., Dempsey, Christopher E.

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Structural implications of hERG K+ channel block by a high-affinity minimally structured blocker von Helliwell, Matthew V., Zhang, Yihong, El Harchi, Aziza, Du, Chunyun, Hancox, Jules C., Dempsey, Christopher E.

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Molecular basis of hERG potassium channel blockade by the class Ic antiarrhythmic flecainide von Melgari, Dario, Zhang, Yihong, El Harchi, Aziza, Dempsey, Christopher E, Hancox, Jules C

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Inhibition of the hERG Potassium Channel by a Methanesulphonate-Free E-4031 Analogue von Helliwell, Matthew V, Zhang, Yihong, El Harchi, Aziza, Dempsey, Christopher E, Hancox, Jules C

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Ranolazine inhibition of hERG potassium channels: Drug–pore interactions and reduced potency against inactivation mutants von Du, Chunyun, Zhang, Yihong, El Harchi, Aziza, Dempsey, Christopher E, Hancox, Jules C

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Evolutionary coupling analysis guides identification of mistrafficking-sensitive variants in cardiac K+ channels: Validation with hERG von Zhang, Yihong, Grimwood, Amy L., Hancox, Jules C., Harmer, Stephen C., Dempsey, Christopher E.

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hERG potassium channel blockade by the HCN channel inhibitor bradycardic agent ivabradine von Melgari, Dario, Brack, Kieran E, Zhang, Chuan, Zhang, Yihong, El Harchi, Aziza, Mitcheson, John S, Dempsey, Christopher E, Ng, G André, Hancox, Jules C

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Complex Ion Effects on Polypeptide Conformational Stability: Chloride and Sulfate Salts of Guanidinium and Tetrapropylammonium von Dempsey, Christopher E, Mason, Philip E, Jungwirth, Pavel

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Origin of Low Mammalian Cell Toxicity in a Class of Highly Active Antimicrobial Amphipathic Helical Peptides von Hawrani, Ayman, Howe, Robin A., Walsh, Timothy R., Dempsey, Christopher E.

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Analysis of α-Dystroglycan/LG Domain Binding Modes: Investigating Protein Motifs That Regulate the Affinity of Isolated LG Domains von Dempsey, Christopher E, Bigotti, Maria Giulia, Adams, Josephine C, Brancaccio, Andrea

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Electrophysiological characterization of the modified hERGT potassium channel used to obtain the first cryo‐EM hERG structure von Zhang, Yihong, Dempsey, Christopher E., Hancox, Jules C.

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Structure, Location, and Lipid Perturbations of Melittin at the Membrane Interface von Hristova, Kalina, Dempsey, Christopher E., White, Stephen H.

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Molecular determinants of hERG potassium channel inhibition by disopyramide von El Harchi, Aziza, Zhang, Yi H, Hussein, Leyla, Dempsey, Christopher E, Hancox, Jules C

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The macrolide drug erythromycin does not protect the hERG channel from inhibition by thioridazine and terfenadine von El Harchi, Aziza, Butler, Andrew S., Zhang, Yihong, Dempsey, Christopher E., Hancox, Jules C.

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Voltage Sensor Gating Charge Transfer in a hERG Potassium Channel Model von Colenso, Charlotte K., Cao, Yang, Sessions, Richard B., Hancox, Jules C., Dempsey, Christopher E.

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Functional and pharmacological characterization of an S5 domain hERG mutation associated with short QT syndrome von Butler, Andrew, Zhang, Yihong, Stuart, A. Graham, Dempsey, Christopher E., Hancox, Jules C.

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Inhibition of the hERG potassium channel by phenanthrene: a polycyclic aromatic hydrocarbon pollutant von Al-Moubarak, Ehab, Shiels, Holly A., Zhang, Yihong, Du, Chunyun, Hanington, Oliver, Harmer, Stephen C., Dempsey, Christopher E., Hancox, Jules C.

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Serine mutation of a conserved threonine in the hERG K+ channel S6-pore region leads to loss-of-function through trafficking impairment von Al-Moubarak, Ehab, Zhang, Yihong, Dempsey, Christopher E., Zhang, Henggui, Harmer, Stephen C., Hancox, Jules C.

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Dissecting Contributions to the Denaturant Sensitivities of Proteins von Dempsey, Christopher E, Piggot, Thomas J, Mason, Philip E

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