Heterogeneity of kinase inhibitor resistance mechanisms in GIST von Liegl, B, Kepten, I, Le, C, Zhu, M, Demetri, GD, Heinrich, MC, Fletcher, CDM, Corless, CL, Fletcher, JA

Volltext

KIT oncogenic signaling mechanisms in imatinib-resistant gastrointestinal stromal tumor: PI3-kinase AKT is a crucial survival pathway von BAUER, S, DUENSING, A, DEMETRI, G. D, FLETCHER, J. A

Volltext

Development, Validation, and Field-Testing of an Instrument for Clinical Assessment of HIV-Associated Neuropathy and Neuropathic Pain in Resource-Restricted and Large Population St... von Woldeamanuel, Yohannes W, Kamerman, Peter R, Veliotes, Demetri G A, Phillips, Tudor J, Asboe, David, Boffito, Marta, Rice, Andrew S C

Volltext

Clinical evaluation of continuous daily dosing of sunitinib malate in patients with advanced gastrointestinal stromal tumour after imatinib failure von George, S, Blay, J.Y, Casali, P.G, Le Cesne, A, Stephenson, P, DePrimo, S.E, Harmon, C.S, Law, C.N.J, Morgan, J.A, Ray-Coquard, I, Tassell, V, Cohen, D.P, Demetri, G.D

Volltext

Clinical outcomes and safety with trabectedin therapy in patients with advanced soft tissue sarcomas following failure of prior chemotherapy: results of a worldwide expanded access... von Samuels, B.L., Chawla, S., Patel, S., von Mehren, M., Hamm, J., Kaiser, P.E., Schuetze, S., Li, J., Aymes, A., Demetri, G.D.

Volltext

Hypertension as a potential biomarker of efficacy in patients with gastrointestinal stromal tumor treated with sunitinib von George, S., Reichardt, P., Lechner, T., Li, S., Cohen, D.P., Demetri, G.D.

Volltext

Phase III study of nilotinib versus best supportive care with or without a TKI in patients with gastrointestinal stromal tumors resistant to or intolerant of imatinib and sunitinib von Reichardt, P., Blay, J.-Y., Gelderblom, H., Schlemmer, M., Demetri, G.D., Bui-Nguyen, B., McArthur, G.A., Yazji, S., Hsu, Y., Galetic, I., Rutkowski, P.

Volltext

A multicenter phase II study of pazopanib in patients with advanced gastrointestinal stromal tumors (GIST) following failure of at least imatinib and sunitinib von Ganjoo, K.N., Villalobos, V.M., Kamaya, A., Fisher, G.A., Butrynski, J.E., Morgan, J.A., Wagner, A.J., D'Adamo, D., McMillan, A., Demetri, G.D., George, S.

Volltext

Phase II clinical trial of neoadjuvant trabectedin in patients with advanced localized myxoid liposarcoma von Gronchi, A., Bui, B.N., Bonvalot, S., Pilotti, S., Ferrari, S., Hohenberger, P., Hohl, R.J., Demetri, G.D., Le Cesne, A., Lardelli, P., Pérez, I., Nieto, A., Tercero, J.C., Alfaro, V., Tamborini, E., Blay, J.Y.

Volltext

A phase I–II study of everolimus (RAD001) in combination with imatinib in patients with imatinib-resistant gastrointestinal stromal tumors von Schöffski, P., Reichardt, P., Blay, J.-Y., Dumez, H., Morgan, J.A., Ray-Coquard, I., Hollaender, N., Jappe, A., Demetri, G.D.

Volltext

Long-term follow-up results of the multicenter phase II trial of regorafenib in patients with metastatic and/or unresectable GI stromal tumor after failure of standard tyrosine kin... von Ben-Ami, E., Barysauskas, C.M., von Mehren, M., Heinrich, M.C., Corless, C.L., Butrynski, J.E., Morgan, J.A., Wagner, A.J., Choy, E., Yap, J.T., Van den Abbeele, A.D., Solomon, S.M., Fletcher, J.A., Demetri, G.D., George, S.

Volltext

Neo-adjuvant chemotherapy for primary high-grade extremity soft tissue sarcoma von Grobmyer, S. R., Maki, R. G., Demetri, G. D., Mazumdar, M., Riedel, E., Brennan, M. F., Singer, S.

Volltext

Numerical evaluation of a heat exchanger with inline tubes of different size for reduced fouling rates von Mavridou, Sofia G., Bouris, Demetri G.

Volltext

Efficacy and tolerability of trabectedin in elderly patients with sarcoma: subgroup analysis from a phase III, randomized controlled study of trabectedin or dacarbazine in patients... von Jones, R.L., Demetri, G.D., Schuetze, S.M., Milhem, M., Elias, A., Van Tine, B.A., Hamm, J., McCarthy, S., Wang, G., Parekh, T., Knoblauch, R., Hensley, M.L., Maki, R.G., Patel, S., von Mehren, M.

Volltext

Advances in the treatment of gastrointestinal stromal tumours von Judson, I, Demetri, G

Volltext

Phase II and Pharmacokinetic Study of Ecteinascidin 743 in Patients With Progressive Sarcomas of Soft Tissues Refractory to Chemotherapy von GARCIA-CARBONERO, R, SUPKO, J. G, MATULONIS, U, MAKI, R. G, LOPEZ, T, PUCHALSKI, T. A, SANCHO, M. A, GOMEZ, J, GUZMAN, C, JIMENO, J, DEMETRI, G. D, MANOLA, J, SEIDEN, M. V, HARMON, D, RYAN, D. P, QUIGLEY, M. T, MERRIAM, P, CANNIFF, J, GOSS, G

Volltext

Ecteinascidin-743 (ET-743) for Chemotherapy-Naive Patients With Advanced Soft Tissue Sarcomas: Multicenter Phase II and Pharmacokinetic Study von GARCIA-CARBONERO, R, SUPKO, J. G, QUIGLEY, M. T, LOPEZ, T, SANCHO, M. A, JIMENO, J, GUZMAN, C, DEMETRI, G. D, MAKI, R. G, MANOLA, J, RYAN, D. P, HARMON, D, PUCHALSKI, T. A, GOSS, G, SEIDEN, M. V, WAXMAN, A

Volltext

Trabectedin is a feasible treatment for soft tissue sarcoma patients regardless of patient age: a retrospective pooled analysis of five phase II trials von Cesne, A L, Judson, I, Maki, R, Grosso, F, Schuetze, S, Mehren, M V, Chawla, S P, Demetri, G D, Nieto, A, Tanovic, A, Blay, J-Y

Volltext

Impact of Urban Morphology on Infiltration-Induced Building Energy Consumption von Jurelionis, Andrius, Bouris, Demetri

Volltext

KIT activation is a ubiquitous feature of gastrointestinal stromal tumors von RUBIN, Brian P, SINGER, Samuel, DEMETRI, George D, FLETCHER, Christopher D. M, FLETCHER, Jonathan A, TSAO, Connie, DUENSING, Anette, LUX, Marcia L, RUIZ, Robert, HIBBARD, Michele K, CHEN, Chang-Jie, SHENG XIAO, TUVESON, David A

Volltext