Discovery of a novel aminopyrazine series as selective PI3Kα inhibitors von Barlaam, Bernard, Cosulich, Sabina, Fitzek, Martina, Germain, Hervé, Green, Stephen, Hanson, Lyndsey L., Harris, Craig S., Hancox, Urs, Hudson, Kevin, Lambert-van der Brempt, Christine, Lamorlette, Maryannick, Magnien, Françoise, Ouvry, Gilles, Page, Ken, Ruston, Linette, Ward, Lara, Delouvrié, Bénédicte

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Design of selective PI3Kα inhibitors starting from a promiscuous pan kinase scaffold von Barlaam, Bernard, Cosulich, Sabina, Fitzek, Martina, Green, Stephen, Harris, Craig S., Hudson, Kevin, Lambert-van der Brempt, Christine, Ouvry, Gilles, Page, Ken, Ruston, Linette, Ward, Lara, Delouvrié, Bénédicte

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Facile preparation and Suzuki–Miyaura cross-coupling of N-2-alkylated 2H-1,2,3-triazole 4-boronates von Davey, Paul R.J., Delouvrié, Bénédicte, Dorison-Duval, Delphine, Germain, Hervé, Harris, Craig S., Magnien, Françoise, Ouvry, Gilles, Tricotet, Thomas

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Discovery and application of iminotriphenylphosphorane as a formal aromatic primary amine protecting group von Delouvrié, Bénédicte, Germain, Hervé, Harris, Craig S., Lamorlette, Maryannick, Lebraud, Honorine, Nguyen, Ha Thi Hoang, Noisier, Anais, Ouvry, Gilles

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Synthetic studies toward cytostatin, a natural product inhibitor of protein phosphatase 2A von Salit, Anne-Frédérique, Meyer, Christophe, Cossy, Janine, Delouvrié, Bénédicte, Hennequin, Laurent

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Facile, diversity-orientated one-pot synthesis of ethyl 1,5-disubstituted-1H-1,2,4-triazole-3-carboxylates von Degorce, Sébastien, Delouvrié, Bénédicte, Davey, Paul R.J., Didelot, Myriam, Germain, Hervé, Harris, Craig S., Brempt, Christine Lambert-van der, Lebraud, Honorine, Ouvry, Gilles

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Structure–activity relationship of a series of non peptidic RGD integrin antagonists targeting α5β1: Part 2 von Delouvrié, Bénédicte, Al-Kadhimi, Katherine, Arnould, Jean-Claude, Barry, Simon T., Cross, Darren A.E., Didelot, Myriam, Gavine, Paul R., Germain, Hervé, Harris, Craig S., Hughes, Adina M., Jude, David A., Kendrew, Jane, Lambert-van der Brempt, Christine, Lohmann, Jean-Jacques, Ménard, Morgan, Mortlock, Andrew A., Pass, Martin, Rooney, Claire, Vautier, Michel, Vincent, Jennifer L., Warin, Nicolas

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Synthesis and structure–activity relationships of thieno[2,3- b]pyrroles as antagonists of the GnRH receptor von Arnould, Jean Claude, Delouvrié, Bénédicte, Boutron, Pascal, Dossetter, Al G., Foote, Kevin M., Hamon, Annie, Hancox, Urs, Harris, Craig S., Hutton, Mike, Lamorlette, Maryannick, Matusiak, Zbigniew

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Novel 4-anilinoquinazolines with C-6 carbon-linked side chains: Synthesis and structure–activity relationship of a series of potent, orally active, EGF receptor tyrosine kinase inh... von Hennequin, Laurent F.A., Ballard, Peter, Boyle, F. Tom, Delouvrié, Bénédicte, Ellston, Rebecca P.A., Halsall, Chris T., Harris, Craig S., Hudson, Kevin, Kendrew, Jane, Pease, J. Elizabeth, Ross, Helen S., Smith, Peter, Vincent, Jennifer L.

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Conjugate Additions to Alkylidene Bis(Sulfoxides) von Brebion, Franck, Vincent, Guillaume, Chelli, Saloua, Kwasnieski, Ophélie, Najera, Francisco, Delouvrié, Bénédicte, Marek, Ilan, Derat, Etienne, Goddard, Jean-Philippe, Malacria, Max, Fensterbank, Louis

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Abstract 2830: Discovery of AZD8835, a potent and selective inhibitor of PI3Kα and PI3Kδ for the treatment of PIK3CA -dependent cancers von Barlaam, Bernard, Cosulich, Sabina, Delouvrie, Benedicte, Fitzek, Martina, Germain, Herve, Green, Stephen, Harris, Craig S., Hudson, Kevin, Lambert-van der Brempt, Christine, Lamorlette, Maryannick, Antoine, Le Griffon, Morgentin, Remy, Ouvry, Gilles, Page, Ken, Pasquet, Georges, Ruston, Linette, Saleh, Twana, Vautier, Michel, Ward, Lara

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Structure–activity relationship of a series of non peptidic RGD integrin antagonists targeting α5β1: Part 1 von Delouvrié, Bénédicte, Al-Kadhimi, Katherine, Arnould, Jean-Claude, Barry, Simon T., Cross, Darren A.E., Didelot, Myriam, Gavine, Paul R., Germain, Hervé, Harris, Craig S., Hughes, Adina M., Jude, David A., Kendrew, Jane, Lambert-van der Brempt, Christine, Lohmann, Jean-Jacques, Ménard, Morgan, Mortlock, Andrew A., Pass, Martin, Rooney, Claire, Vautier, Michel, Vincent, Jennifer L., Warin, Nicolas

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Structureaactivity relationship of a series of non peptidic RGD integrin antagonists targeting I-5I21: Part 1 von Delouvrie, Benedicte, Al-Kadhimi, Katherine, Arnould, Jean-Claude, Barry, Simon T, Cross, Darren AE, Didelot, Myriam, Gavine, Paul R, Germain, Herve, Harris, Craig S, Hughes, Adina M, Jude, David A, Kendrew, Jane, Lambert-van der Brempt, Christine, Lohmann, Jean-Jacques, Menard, Morgan, Mortlock, Andrew A, Pass, Martin, Rooney, Claire, Vautier, Michel, Vincent, Jennifer L, Warin, Nicolas

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Structureaactivity relationship of a series of non peptidic RGD integrin antagonists targeting I-5I21: Part 2 von Delouvrie, Benedicte, Al-Kadhimi, Katherine, Arnould, Jean-Claude, Barry, Simon T, Cross, Darren AE, Didelot, Myriam, Gavine, Paul R, Germain, Herve, Harris, Craig S, Hughes, Adina M, Jude, David A, Kendrew, Jane, Lambert-van der Brempt, Christine, Lohmann, Jean-Jacques, Menard, Morgan, Mortlock, Andrew A, Pass, Martin, Rooney, Claire, Vautier, Michel, Vincent, Jennifer L, Warin, Nicolas

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Fischer synthesis of isomeric thienopyrrole LHRH antagonists von Andrews, David M., Arnould, Jean-Claude, Boutron, Pascal, Délouvrie, Bénédicte, Delvare, Christian, Foote, Kevin M., Hamon, Annie, Harris, Craig S., Lambert-van der Brempt, Christine, Lamorlette, Maryannick, Matusiak, Zbegniew M.

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Discovery of 1-(4-(5-(5-amino-6-(5-tert-butyl-1,3,4-oxadiazol-2-yl)pyrazin-2-yl)-1-ethyl-1,2,4-triazol-3-yl)piperidin-1-yl)-3-hydroxypropan-1-one (AZD8835): A potent and selective... von Barlaam, Bernard, Cosulich, Sabina, Delouvrié, Bénédicte, Ellston, Rebecca, Fitzek, Martina, Germain, Hervé, Green, Stephen, Hancox, Urs, Harris, Craig S., Hudson, Kevin, Lambert-van der Brempt, Christine, Lebraud, Honorine, Magnien, Françoise, Lamorlette, Maryannick, Le Griffon, Antoine, Morgentin, Rémy, Ouvry, Gilles, Page, Ken, Pasquet, Georges, Polanska, Urszula, Ruston, Linette, Saleh, Twana, Vautier, Michel, Ward, Lara

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AMINOPYRAZINE DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS THEREOF FOR USE IN THE TREATMENT OF CANCER von BARLAAM, BERNARD CHRISTOPHE, HARRIS, CRAIG STEVEN, LAMBERT-VAN DER BREMPT, CHRISTINE MARIE PAUL, REID, GARY PATRICK, BERRY, DAVID, DELOUVRIE, BENEDICTE, OUVRY, GILLES, TOMKINSON, GARY PETER

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Chemical compounds von Delouvrie Benedicte, Ouvry Gilles, Tomkinson Gary Peter, Berry David, Barlaam Bernard Christophe, Lambert-Van der Brempt Christine Marie Paul, Reid Gary Patrick, Harris Craig Steven

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Recent Developments in the Construction of trans-Fused Polycyclic Ethers von Evans, P. Andrew, Delouvrie, Benedicte

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ChemInform Abstract: Discovery and Application of Iminotriphenylphosphorane as a Formal Aromatic Primary Amine Protecting Group von Delouvrie, Benedicte, Germain, Herve, Harris, Craig S., Lamorlette, Maryannick, Lebraud, Honorine, Nguyen, Ha Thi Hoang, Noisier, Anais, Ouvry, Gilles

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