Diagnostic revision of 206 adult gliomas (including 40 oligoastrocytomas) based on ATRX, IDH1/2 and 1p/19q status von Mellai, Marta, Annovazzi, Laura, Senetta, Rebecca, Dell’Aglio, Carmine, Mazzucco, Marta, Cassoni, Paola, Schiffer, Davide

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The Combination of Sorafenib and Everolimus Abrogates mTORC1 and mTORC2 Upregulation in Osteosarcoma Preclinical Models von PIGNOCHINO, Ymera, DELL'AGLIO, Carmine, D'AMBROSIO, Lorenzo, FAGIOLI, Franca, FERRARI, Stefano, ALBERGHINI, Marco, PICCI, Piero, AGLIETTA, Massimo, GRIGNANI, Giovanni, BASIRICO, Marco, CAPOZZI, Federica, SOSTER, Marco, MARCHIO, Serena, BRUNO, Stefania, GAMMAITONI, Loretta, SANGIOLO, Dario, TORCHIARO, Erica

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ERBB3 overexpression due to miR-205 inactivation confers sensitivity to FGF, metabolic activation, and liability to ERBB3 targeting in glioblastoma von De Bacco, Francesca, Orzan, Francesca, Erriquez, Jessica, Casanova, Elena, Barault, Ludovic, Albano, Raffaella, D’Ambrosio, Antonio, Bigatto, Viola, Reato, Gigliola, Patanè, Monica, Pollo, Bianca, Kuesters, Geoffrey, Dell’Aglio, Carmine, Casorzo, Laura, Pellegatta, Serena, Finocchiaro, Gaetano, Comoglio, Paolo M., Boccaccio, Carla

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The expression of LINE1‐MET chimeric transcript identifies a subgroup of aggressive breast cancers von Miglio, Umberto, Berrino, Enrico, Panero, Mara, Ferrero, Giulio, Coscujuela Tarrero, Lucia, Miano, Valentina, Dell'Aglio, Carmine, Sarotto, Ivana, Annaratone, Laura, Marchiò, Caterina, Comoglio, Paolo M., De Bortoli, Michele, Pasini, Barbara, Venesio, Tiziana, Sapino, Anna

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Cytokine-Induced Killer Cells Eradicate Bone and Soft-Tissue Sarcomas von SANGIOLO, Dario, MESIANO, Giulia, SAROTTO, Ivana, MIANO, Sara, FERRERO, Ivana, CARNEVALE-SCHIANCA, Fabrizio, PIGNOCHINO, Ymera, SASSI, Francesco, BERTOTTI, Andrea, PIACIBELLO, Wanda, FAGIOLI, Franca, AGLIETTA, Massimo, GAMMAITONI, Loretta, GRIGNANI, Giovanni, LEUCI, Valeria, TODOROVIC, Maja, GIRAUDO, Lidia, CAMMARATA, Cristina, DELL'AGLIO, Carmine, D'AMBROSIO, Lorenzo, PISACANE, Alberto

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Aurora kinase A gene copy number is associated with the malignant transformation of colorectal adenomas but not with the serrated neoplasia progression von Casorzo, Laura, BSc, Dell'Aglio, Carmine, BSc, Sarotto, Ivana, BSc, Risio, Mauro, MD

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Establishment and characterization of a human intrahepatic cholangiocarcinoma cell line derived from an Italian patient von Cavalloni, Giuliana, Peraldo-Neia, Caterina, Varamo, Chiara, Casorzo, Laura, Dell’Aglio, Carmine, Bernabei, Paola, Chiorino, Giovanna, Aglietta, Massimo, Leone, Francesco

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The Dilemma of HER2 Double-equivocal Breast Carcinomas: Genomic Profiling and Implications for Treatment von Marchiò, Caterina, Dell’Orto, Patrizia, Annaratone, Laura, Geyer, Felipe C, Venesio, Tiziana, Berrino, Enrico, Verdun di Cantogno, Ludovica, Garofoli, Andrea, Rangel, Nelson, Casorzo, Laura, dell’Aglio, Carmine, Gugliotta, Patrizia, Trisolini, Elena, Beano, Alessandra, Pietribiasi, Francesca, Orlassino, Renzo, Cassoni, Paola, Pich, Achille, Montemurro, Filippo, Mottolese, Marcella, Vincent-Salomon, Anne, Penault-Llorca, Frédérique, Medico, Enzo, Ng, Charlotte K.Y, Viale, Giuseppe, Sapino, Anna

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The combination of sorafenib and everolimus shows antitumor activity in preclinical models of malignant pleural mesothelioma von Pignochino, Ymera, Dell'Aglio, Carmine, Inghilleri, Simona, Zorzetto, Michele, Basiricò, Marco, Capozzi, Federica, Canta, Marta, Piloni, Davide, Cemmi, Francesca, Sangiolo, Dario, Gammaitoni, Loretta, Soster, Marco, Marchiò, Serena, Pozzi, Ernesto, Morbini, Patrizia, Luisetti, Maurizio, Aglietta, Massimo, Grignani, Giovanni, Stella, Giulia M

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PARP1 expression drives the synergistic antitumor activity of trabectedin and PARP1 inhibitors in sarcoma preclinical models von Pignochino, Ymera, Capozzi, Federica, D'Ambrosio, Lorenzo, Dell'Aglio, Carmine, Basiricò, Marco, Canta, Marta, Lorenzato, Annalisa, Vignolo Lutati, Francesca, Aliberti, Sandra, Palesandro, Erica, Boccone, Paola, Galizia, Danilo, Miano, Sara, Chiabotto, Giulia, Napione, Lucia, Gammaitoni, Loretta, Sangiolo, Dario, Benassi, Maria Serena, Pasini, Barbara, Chiorino, Giovanna, Aglietta, Massimo, Grignani, Giovanni

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Ex Vivo Allogeneic Stimulation Significantly Improves Expansion of Cytokine-Induced Killer Cells Without Increasing Their Alloreactivity Across HLA Barriers von TODOROVIC, Maja, MESIANO, Giulia, PIACIBELLO, Wanda, ELIA, Angela Rita, PIGNOCHINO, Ymera, DELL'AGLIO, Carmine, GRIGNANI, Giovanni, CIGNETTI, Alessandro, AGLIETTA, Massimo, SANGIOLO, Dario, GAMMAITONI, Loretta, LEUCI, Valeria, GIRAUDO DIEGO, Lidia, CAMMARATA, Cristina, JORDANEY, Noela, CARNEVALE-SCHIANCA, Fabrizio, GALLO, Susanna, FAGIOLI, Franca

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The Dilemma of HER2 Double-equivocal Breast Carcinomas von Marchio, Caterina, Dell'Orto, Patrizia, Annaratone, Anna, Geyer, Felipe, Venesio, Tiziana, Berrino, Enrico, Verdun Di Cantogno, Ludovica, Garofoli, Andrea, Rangel, Nelson, Casorzo, Laura, Dell'Aglio, Carmine, Gugliotta, Patrizia, Trisolini, Elena, Beano, Alessandra, Pietribiasi, Francesca, Orlassino, Renzo, Cassoni, Paola, Pich, Achille, Montemurro, Filippo, Mottolese, Marcella, Vincent-Salomon, Anne, Penault-Llorca, Frédérique, Medico, Enzo, Ng, Charlotte, Viale, Giuseppe, Sapino, Anna, Dell’orto, Patrizia, Dell’aglio, Carmine, Ng, Charlotte K.Y.

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Abstract 942: ErbB3 overexpression unleashed by miR-205 epigenetic silencing is a therapeutic target in glioblastoma von De Bacco, Francesca, Orzan, Francesca, Erriquez, Jessica, Casanova, Elena, Barault, Ludovic, Albano, Raffaella, D'Ambrosio, Antonio, Bigatto, Viola, Reato, Gigliola, Patané, Monica, Pollo, Bianca, Kuesters, Geoffrey, Dell'Aglio, Carmine, Casorzo, Laura, Pellegatta, Serena, Finocchiaro, Gaetano, Comoglio, Paolo M., Boccaccio, Carla

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Abstract A087: Empowering precision medicine in metastatic colorectal cancer: preliminary results from the FUNNEL platform von Martino, Cosimo, Berrino, Enrico, Dell'Aglio, Carmine, Casorzo, Laura, Panero, Mara, Siena, Salvatore, Sartore-Bianchi, Andrea, Cassingena, Andrea, Zagonel, Vittorina, Lonardi, Sara, Loupakis, Fotios, Tonini, Giuseppe, Racca, Patrizia, Trusolino, Livio, Bertotti, Andrea, Depetris, Ilaria, Balsamo, Antonella, Sapino, Anna, Marsoni, Silvia

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Abstract LB-213: The antitumor effect of trabectedin (TR) is potentiated by olaparib (OL) in preclinical models of bone and soft tissue sarcomas (STS) von Pignochino, Ymera, Capozzi, Federica, Dell'aglio, Carmine, Basiricò, Marco, D'ambrosio, Lorenzo, Galizia, Danilo, Palesandro, Erica, Benassi, Maria Serena, Aglietta, Massimo, Grignani, Giovanni

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Abstract LB-366: Everolimus (EV) potentiates Sorafenib (SOR)activity in osteosarcoma (OS) preclinical models: a combination targeting the crosstalk between ERK1/2 and mTORC1/2 sign... von Pignochino, Ymera, Dell'Aglio, Carmine, Basiricò, Marco, Capozzi, Federica, Tarraran, Loredana, Soster, Marco, Marchiò, Serena, Bruno, Stefania, Gammaitoni, Loretta, Sangiolo, Dario, D'ambrosio, Lorenzo, Picci, Piero, Aglietta, Massimo, Grignani, Giovanni

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Abstract 3709: PARP1 expression (PARP1expr) drives synergy between PARP1 inhibitors (PARP1-Is) and trabectedin (TR) von Pignochino, Ymera, Capozzi, Federica, D’ambrosio, Lorenzo, Dell’aglio, Carmine, Basiricò, Marco, Boccone, Paola, Palesandro, Erica, Gammaitoni, Loretta, Sangiolo, Dario, Benassi, Maria Serena, Aglietta, Massimo, Grignani, Giovanni

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Additional file 1: Table S1. of PARP1 expression drives the synergistic antitumor activity of trabectedin and PARP1 inhibitors in sarcoma preclinical models von Ymera Pignochino, Capozzi, Federica, D’Ambrosio, Lorenzo, Dell’Aglio, Carmine, Basiricò, Marco, Canta, Marta, Lorenzato, Annalisa, Lutati, Francesca Vignolo, Aliberti, Sandra, Palesandro, Erica, Boccone, Paola, Galizia, Danilo, Miano, Sara, Chiabotto, Giulia, Napione, Lucia, Gammaitoni, Loretta, Sangiolo, Dario, Benassi, Maria, Pasini, Barbara, Chiorino, Giovanna, Aglietta, Massimo, Grignani, Giovanni

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Additional file 2: Figure S1. of PARP1 expression drives the synergistic antitumor activity of trabectedin and PARP1 inhibitors in sarcoma preclinical models von Ymera Pignochino, Capozzi, Federica, D’Ambrosio, Lorenzo, Dell’Aglio, Carmine, Basiricò, Marco, Canta, Marta, Lorenzato, Annalisa, Lutati, Francesca Vignolo, Aliberti, Sandra, Palesandro, Erica, Boccone, Paola, Galizia, Danilo, Miano, Sara, Chiabotto, Giulia, Napione, Lucia, Gammaitoni, Loretta, Sangiolo, Dario, Benassi, Maria, Pasini, Barbara, Chiorino, Giovanna, Aglietta, Massimo, Grignani, Giovanni

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