Ipilimumab 10 mg/kg versus ipilimumab 3 mg/kg in patients with unresectable or metastatic melanoma: a randomised, double-blind, multicentre, phase 3 trial von Ascierto, Paolo A, Dr, Del Vecchio, Michele, MD, Robert, Caroline, Prof, Mackiewicz, Andrzej, Prof, Chiarion-Sileni, Vanna, MD, Arance, Ana, MD, Lebbé, Céleste, Prof, Bastholt, Lars, MD, Hamid, Omid, MD, Rutkowski, Piotr, Prof, McNeil, Catriona, MD, Garbe, Claus, Prof, Loquai, Carmen, MD, Dreno, Brigitte, Prof, Thomas, Luc, Prof, Grob, Jean-Jacques, Prof, Liszkay, Gabriella, Prof, Nyakas, Marta, MD, Gutzmer, Ralf, Prof, Pikiel, Joanna, MD, Grange, Florent, MD, Hoeller, Christoph, MD, Ferraresi, Virginia, MD, Smylie, Michael, MD, Schadendorf, Dirk, Prof, Mortier, Laurent, Prof, Svane, Inge Marie, MD, Hennicken, Delphine, MSc, Qureshi, Anila, MD, Maio, Michele, MD

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Binimetinib versus dacarbazine in patients with advanced NRAS -mutant melanoma (NEMO): a multicentre, open-label, randomised, phase 3 trial von Dummer, Reinhard, Prof, Schadendorf, Dirk, Prof, Ascierto, Paolo A, MD, Arance, Ana, MD, Dutriaux, Caroline, MD, Di Giacomo, Anna Maria, MD, Rutkowski, Piotr, Prof, Del Vecchio, Michele, MD, Gutzmer, Ralf, Prof, Mandala, Mario, MD, Thomas, Luc, Prof, Demidov, Lev, Prof, Garbe, Claus, Prof, Hogg, David, MD, Liszkay, Gabriella, Prof, Queirolo, Paola, MD, Wasserman, Ernesto, MD, Ford, James, MS, Weill, Marine, MSc, Sirulnik, L Andres, MD, Jehl, Valentine, MSc, Bozón, Viviana, MD, Long, Georgina V, Prof, Flaherty, Keith, MD

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Immune-related adverse events correlate with improved survival in patients undergoing anti-PD1 immunotherapy for metastatic melanoma von Indini, Alice, Di Guardo, Lorenza, Cimminiello, Carolina, Prisciandaro, Michele, Randon, Giovanni, De Braud, Filippo, Del Vecchio, Michele

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Immunotherapy of Metastatic Melanoma Using Genetically Engineered GD2-Specific T cells von YVON, Eric, DEL VECCHIO, Michele, SAVOLDO, Barbara, HOYOS, Valentina, DUTOUR, Aurélie, ANICHINI, Andrea, DOTTI, Gianpietro, BRENNER, Malcolm K

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Adjuvant nivolumab versus ipilimumab in resected stage IIIB–C and stage IV melanoma (CheckMate 238): 4-year results from a multicentre, double-blind, randomised, controlled, phase... von Ascierto, Paolo A, Del Vecchio, Michele, Mandalá, Mario, Gogas, Helen, Arance, Ana M, Dalle, Stephane, Cowey, C Lance, Schenker, Michael, Grob, Jean-Jacques, Chiarion-Sileni, Vanna, Márquez-Rodas, Iván, Butler, Marcus O, Maio, Michele, Middleton, Mark R, de la Cruz-Merino, Luis, Arenberger, Petr, Atkinson, Victoria, Hill, Andrew, Fecher, Leslie A, Millward, Michael, Khushalani, Nikhil I, Queirolo, Paola, Lobo, Maurice, de Pril, Veerle, Loffredo, John, Larkin, James, Weber, Jeffrey

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miR-146a-5p impairs melanoma resistance to kinase inhibitors by targeting COX2 and regulating NFkB-mediated inflammatory mediators von Vergani, Elisabetta, Dugo, Matteo, Cossa, Mara, Frigerio, Simona, Di Guardo, Lorenza, Gallino, Gianfrancesco, Mattavelli, Ilaria, Vergani, Barbara, Lalli, Luca, Tamborini, Elena, Valeri, Barbara, Gargiuli, Chiara, Shahaj, Eriomina, Ferrarini, Marina, Ferrero, Elisabetta, Gomez Lira, Macarena, Huber, Veronica, Vecchio, Michele Del, Sensi, Marialuisa, Leone, Biagio Eugenio, Santinami, Mario, Rivoltini, Licia, Rodolfo, Monica, Vallacchi, Viviana

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Dabrafenib, trametinib and pembrolizumab or placebo in BRAF-mutant melanoma von Ascierto, Paolo Antonio, Ferrucci, Pier Francesco, Fisher, Rosalie, Del Vecchio, Michele, Atkinson, Victoria, Schmidt, Henrik, Schachter, Jacob, Queirolo, Paola, Long, Georgina V., Di Giacomo, Anna Maria, Svane, Inge Marie, Lotem, Michal, Bar-Sela, Gil, Couture, Felix, Mookerjee, Bijoyesh, Ghori, Razi, Ibrahim, Nageatte, Moreno, Blanca Homet, Ribas, Antoni

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Pembrolizumab versus placebo as adjuvant therapy in completely resected stage IIB or IIC melanoma (KEYNOTE-716): a randomised, double-blind, phase 3 trial von Luke, Jason J, Rutkowski, Piotr, Queirolo, Paola, Del Vecchio, Michele, Mackiewicz, Jacek, Chiarion-Sileni, Vanna, de la Cruz Merino, Luis, Khattak, Muhammad A, Schadendorf, Dirk, Long, Georgina V, Ascierto, Paolo A, Mandala, Mario, De Galitiis, Federica, Haydon, Andrew, Dummer, Reinhard, Grob, Jean-Jacques, Robert, Caroline, Carlino, Matteo S, Mohr, Peter, Poklepovic, Andrew, Sondak, Vernon K, Scolyer, Richard A, Kirkwood, John M, Chen, Ke, Diede, Scott J, Ahsan, Sama, Ibrahim, Nageatte, Eggermont, Alexander M M

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Combination of Immunotherapy and Brain Radiotherapy in Metastatic Melanoma: A Retrospective Analysis von Galli, Giulia, Cavalieri, Stefano, Di Guardo, Lorenza, Cimminiello, Carolina, Nichetti, Federico, Corti, Francesca, Garcia, Monica Alicia, Pappalardi, Brigida, Fallai, Carlo, de Braud, Filippo, Platania, Marco, Del Vecchio, Michele

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Pembrolizumab versus placebo as adjuvant therapy in resected stage IIB or IIC melanoma (KEYNOTE-716): distant metastasis-free survival results of a multicentre, double-blind, rando... von Long, Georgina V, Luke, Jason J, Khattak, Muhammad A, de la Cruz Merino, Luis, Del Vecchio, Michele, Rutkowski, Piotr, Spagnolo, Francesco, Mackiewicz, Jacek, Chiarion-Sileni, Vanna, Kirkwood, John M, Robert, Caroline, Grob, Jean-Jacques, de Galitiis, Federica, Schadendorf, Dirk, Carlino, Matteo S, Mohr, Peter, Dummer, Reinhard, Gershenwald, Jeffrey E, Yoon, Charles H, Wu, Xi Lawrence, Fukunaga-Kalabis, Mizuho, Krepler, Clemens, Eggermont, Alexander M M, Ascierto, Paolo A

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Cutaneous melanoma in adolescents and young adults von Indini, Alice, Brecht, Ines, Del Vecchio, Michele, Sultan, Iyad, Signoroni, Stefano, Ferrari, Andrea

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Dabrafenib plus trametinib in patients with BRAFV600 -mutant melanoma brain metastases (COMBI-MB): a multicentre, multicohort, open-label, phase 2 trial von Davies, Michael A, Dr, Saiag, Philippe, Prof, Robert, Caroline, Prof, Grob, Jean-Jacques, Prof, Flaherty, Keith T, Prof, Arance, Ana, MD, Chiarion-Sileni, Vanna, MD, Thomas, Luc, Prof, Lesimple, Thierry, MD, Mortier, Laurent, Prof, Moschos, Stergios J, MD, Hogg, David, MD, Márquez-Rodas, Iván, Prof, Del Vecchio, Michele, Prof, Lebbé, Céleste, Prof, Meyer, Nicolas, Prof, Zhang, Ying, PhD, Huang, Yingjie, MD, Mookerjee, Bijoyesh, MD, Long, Georgina V, Prof

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Interleukin-12: Biological Properties and Clinical Application von DEL VECCHIO, Michele, BAJETTA, Emilio, CANOVA, Stefania, LOTZE, Michael T, WESA, Amy, PARMIANI, Giorgio, ANICHINI, Andrea

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The Pan-Immune-Inflammation Value in Patients with Metastatic Melanoma Receiving First-Line Therapy von Fucà, Giovanni, Beninato, Teresa, Bini, Marta, Mazzeo, Laura, Di Guardo, Lorenza, Cimminiello, Carolina, Randon, Giovanni, Apollonio, Giulia, Bisogno, Ilaria, Del Vecchio, Marta, Lauria Pantano, Claudia, Di Nicola, Massimo, de Braud, Filippo, Del Vecchio, Michele

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KEYNOTE-022 part 3: a randomized, double-blind, phase 2 study of pembrolizumab, dabrafenib, and trametinib in BRAF-mutant melanoma von Ferrucci, Pier Francesco, Di Giacomo, Anna Maria, Del Vecchio, Michele, Atkinson, Victoria, Schmidt, Henrik, Schachter, Jacob, Queirolo, Paola, Long, Georgina V, Stephens, Rosalie, Svane, Inge Marie, Lotem, Michal, Abu-Amna, Mahmoud, Gasal, Eduard, Ghori, Razi, Diede, Scott J, Croydon, Elizabeth S, Ribas, Antoni, Ascierto, Paolo Antonio

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Investigating the role of immunotherapy in advanced/recurrent female genital tract melanoma: a preliminary experience von Indini, Alice, Di Guardo, Lorenza, Cimminiello, Carolina, Lorusso, Domenica, Raspagliesi, Francesco, Del Vecchio, Michele

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Gut Microbiota, Metabolome, and Body Composition Signatures of Response to Therapy in Patients with Advanced Melanoma von Vandoni, Giulia, D'Amico, Federica, Fabbrini, Marco, Mariani, Luigi, Sieri, Sabina, Casirati, Amanda, Di Guardo, Lorenza, Del Vecchio, Michele, Anichini, Andrea, Mortarini, Roberta, Sgambelluri, Francesco, Celano, Giuseppe, Serale, Nadia, De Angelis, Maria, Brigidi, Patrizia, Gavazzi, Cecilia, Turroni, Silvia

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Retrospective-Prospective Observational Study of Italian Patients Treated in Melanoma Adjuvant Cohort MAP-MADAM (Maximing ADjuvAnt MAP): Interim Analysis von Consoli, Francesca, Tucci, Marco, Pigozzo, Jacopo, Simeone, Ester, Spagnolo, Francesco, Troiani, Teresa, Morgese, Francesca, Del Vecchio, Michele, Melotti, Barbara, Tronconi, Maria Chiara, Morelli, Maria Francesca, Grosso, Federica, Merelli, Barbara, Marcon, Ilaria, Valsecchi, Diletta, Quaglino, Pietro

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T Lymphocytes Redirected against the Chondroitin Sulfate Proteoglycan-4 Control the Growth of Multiple Solid Tumors both In Vitro and In Vivo von GELDRES, Claudia, SAVOLDO, Barbara, DOTTI, Gianpietro, HOYOS, Valentina, CARUANA, Ignazio, MING ZHANG, YVON, Eric, DEL VECCHIO, Michele, CREIGHTON, Chad J, ITTMANN, Michael, FERRONE, Soldano

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Characterization and management of neurological adverse events during immune-checkpoint inhibitors treatment: an Italian multicentric experience von Diamanti, Luca, Picca, Alberto, Bini, Paola, Gastaldi, Matteo, Alfonsi, Enrico, Pichiecchio, Anna, Rota, Eugenia, Rudà, Roberta, Bruno, Francesco, Villani, Veronica, Galiè, Edvina, Vogrig, Alberto, Valente, Mariarosaria, Zoccarato, Marco, Poretto, Valentina, Giometto, Bruno, Cimminiello, Carolina, Del Vecchio, Michele, Marchioni, Enrico

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