A Phase 2 Trial of Ponatinib in Philadelphia Chromosome–Positive Leukemias von Cortes, J.E, Kim, D.-W, Pinilla-Ibarz, J, le Coutre, P, Paquette, R, Chuah, C, Nicolini, F.E, Apperley, J.F, Khoury, H.J, Talpaz, M, DiPersio, J, DeAngelo, D.J, Abruzzese, E, Rea, D, Baccarani, M, Müller, M.C, Gambacorti-Passerini, C, Wong, S, Lustgarten, S, Rivera, V.M, Clackson, T, Turner, C.D, Haluska, F.G, Guilhot, F, Deininger, M.W, Hochhaus, A, Hughes, T, Goldman, J.M, Shah, N.P, Kantarjian, H

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Efficacy, safety, and survival with ruxolitinib in patients with myelofibrosis: results of a median 3-year follow-up of COMFORT-I von Verstovsek, Srdan, Mesa, Ruben A, Gotlib, Jason, Levy, Richard S, Gupta, Vikas, DiPersio, John F, Catalano, John V, Deininger, Michael W N, Miller, Carole B, Silver, Richard T, Talpaz, Moshe, Winton, Elliott F, Harvey, Jr, Jimmie H, Arcasoy, Murat O, Hexner, Elizabeth O, Lyons, Roger M, Raza, Azra, Vaddi, Kris, Sun, William, Peng, Wei, Sandor, Victor, Kantarjian, Hagop

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A pooled analysis of overall survival in COMFORT-I and COMFORT-II, 2 randomized phase III trials of ruxolitinib for the treatment of myelofibrosis von Vannucchi, Alessandro M, Kantarjian, Hagop M, Kiladjian, Jean-Jacques, Gotlib, Jason, Cervantes, Francisco, Mesa, Ruben A, Sarlis, Nicholas J, Peng, Wei, Sandor, Victor, Gopalakrishna, Prashanth, Hmissi, Abdel, Stalbovskaya, Viktoriya, Gupta, Vikas, Harrison, Claire, Verstovsek, Srdan

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Imatinib pharmacokinetics and its correlation with response and safety in chronic-phase chronic myeloid leukemia: a subanalysis of the IRIS study von Larson, Richard A., Druker, Brian J., Guilhot, Francois, O'Brien, Stephen G., Riviere, Gilles J., Krahnke, Tillmann, Gathmann, Insa, Wang, Yanfeng

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Efficacy of imatinib dose escalation in patients with chronic myeloid leukemia in chronic phase von Kantarjian, Hagop M., Larson, Richard A., Guilhot, Francois, O'Brien, Stephen G., Mone, Manisha, Rudoltz, Marc, Krahnke, Tillmann, Cortes, Jorge, Druker, Brian J.

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Scrum Training for Product Configuration Systems Development von Shafiee, Sara, Wautelet, Yves

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Rumor, Diplomacy and War in Enlightenment Paris von Deininger, M. A.

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Ponatinib in Refractory Philadelphia Chromosome–Positive Leukemias von Cortes, Jorge E, Kantarjian, Hagop, Shah, Neil P, Bixby, Dale, Mauro, Michael J, Flinn, Ian, O'Hare, Thomas, Hu, Simin, Narasimhan, Narayana I, Rivera, Victor M, Clackson, Tim, Turner, Christopher D, Haluska, Frank G, Druker, Brian J, Deininger, Michael W.N, Talpaz, Moshe

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Asciminib in Chronic Myeloid Leukemia after ABL Kinase Inhibitor Failure von Hughes, Timothy P, Mauro, Michael J, Cortes, Jorge E, Minami, Hironobu, Rea, Delphine, DeAngelo, Daniel J, Breccia, Massimo, Goh, Yeow-Tee, Talpaz, Moshe, Hochhaus, Andreas, le Coutre, Philipp, Ottmann, Oliver, Heinrich, Michael C, Steegmann, Juan L, Deininger, Michael W.N, Janssen, Jeroen J.W.M, Mahon, Francois-Xavier, Minami, Yosuke, Yeung, David, Ross, David M, Tallman, Martin S, Park, Jae H, Druker, Brian J, Hynds, David, Duan, Yuyan, Meille, Christophe, Hourcade-Potelleret, Florence, Vanasse, K. Gary, Lang, Fabian, Kim, Dong-Wook

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Long-term treatment with ruxolitinib for patients with myelofibrosis: 5-year update from the randomized, double-blind, placebo-controlled, phase 3 COMFORT-I trial von Verstovsek, Srdan, Mesa, Ruben A, Gotlib, Jason, Gupta, Vikas, DiPersio, John F, Catalano, John V, Deininger, Michael W N, Miller, Carole B, Silver, Richard T, Talpaz, Moshe, Winton, Elliott F, Harvey, Jr, Jimmie H, Arcasoy, Murat O, Hexner, Elizabeth O, Lyons, Roger M, Paquette, Ronald, Raza, Azra, Jones, Mark, Kornacki, Deanna, Sun, Kang, Kantarjian, Hagop

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Rising Global Interest in Farmland: Can It Yield Sustainable and Equitable Benefits? von Thomson, Kenneth J, Deininger, Byerlee, Lindsay, Norton, Selod, Stickler, K, D, J, A, H, M

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Bosutinib Versus Imatinib for Newly Diagnosed Chronic Myeloid Leukemia: Results From the Randomized BFORE Trial von Cortes, Jorge E, Gambacorti-Passerini, Carlo, Deininger, Michael W, Mauro, Michael J, Chuah, Charles, Kim, Dong-Wook, Dyagil, Irina, Glushko, Nataliia, Milojkovic, Dragana, le Coutre, Philipp, Garcia-Gutierrez, Valentin, Reilly, Laurence, Jeynes-Ellis, Allison, Leip, Eric, Bardy-Bouxin, Nathalie, Hochhaus, Andreas, Brümmendorf, Tim H

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In vitro activity of Bcr-Abl inhibitors AMN107 and BMS-354825 against clinically relevant imatinib-resistant Abl kinase domain mutants von O'HARE, Thomas, WALTERS, Denise K, DRUKER, Brian J, STOFFREGEN, Eric P, TAIPING JIA, MANLEY, Paul W, MESTAN, Jürgen, COWAN-JACOB, Sandra W, LEE, Francis Y, HEINRICH, Michael C, DEININGER, Michael W. N

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Novel inhibitors of cholesterol degradation in Mycobacterium tuberculosis reveal how the bacterium's metabolism is constrained by the intracellular environment von VanderVen, Brian C, Fahey, Ruth J, Lee, Wonsik, Liu, Yancheng, Abramovitch, Robert B, Memmott, Christine, Crowe, Adam M, Eltis, Lindsay D, Perola, Emanuele, Deininger, David D, Wang, Tiansheng, Locher, Christopher P, Russell, David G

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Long-Term Outcomes of Imatinib Treatment for Chronic Myeloid Leukemia von Hochhaus, Andreas, Larson, Richard A, Guilhot, François, Radich, Jerald P, Branford, Susan, Hughes, Timothy P, Baccarani, Michele, Deininger, Michael W, Cervantes, Francisco, Fujihara, Satoko, Ortmann, Christine-Elke, Menssen, Hans D, Kantarjian, Hagop, O’Brien, Stephen G, Druker, Brian J

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Strong and deep Atlantic meridional overturning circulation during the last glacial cycle von Böhm, E., Lippold, J., Gutjahr, M., Frank, M., Blaser, P., Antz, B., Fohlmeister, J., Frank, N., Andersen, M. B., Deininger, M.

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Blockade of JAK2-mediated extrinsic survival signals restores sensitivity of CML cells to ABL inhibitors von Traer, E, MacKenzie, R, Snead, J, Agarwal, A, Eiring, A M, O'Hare, T, Druker, B J, Deininger, M W

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Dasatinib (BMS-354825), a dual SRC/ABL kinase inhibitor, inhibits the kinase activity of wild-type, juxtamembrane, and activation loop mutant KIT isoforms associated with human mal... von SCHITTENHELM, Marcus M, SHIRAGA, Sharon, SCHROEDER, Arin, CORBIN, Amie S, GRIFFITH, Diana, LEE, Francis Y, BOKEMEYER, Carsten, DEININGER, Michael W. N, DRUKER, Brian J, HEINRICH, Michael C

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Heavy Metal Exposure Influences Double Strand Break DNA Repair Outcomes von Morales, Maria E, Derbes, Rebecca S, Ade, Catherine M, Ortego, Jonathan C, Stark, Jeremy, Deininger, Prescott L, Roy-Engel, Astrid M

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European LeukemiaNet 2020 recommendations for treating chronic myeloid leukemia von Hochhaus, A., Baccarani, M., Silver, R. T., Schiffer, C., Apperley, J. F., Cervantes, F., Clark, R. E., Cortes, J. E., Deininger, M. W., Guilhot, F., Hjorth-Hansen, H., Hughes, T. P., Janssen, J. J. W. M., Kantarjian, H. M., Kim, D. W., Larson, R. A., Lipton, J. H., Mahon, F. X., Mayer, J., Nicolini, F., Niederwieser, D., Pane, F., Radich, J. P., Rea, D., Richter, J., Rosti, G., Rousselot, P., Saglio, G., Saußele, S., Soverini, S., Steegmann, J. L., Turkina, A., Zaritskey, A., Hehlmann, R.

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