Bystander effect of purine nucleoside analogues in HSV-1tk suicide gene therapy is superior to that of pyrimidine nucleoside analogues von DEGREVE, B, DE CLERCQ, E, BALZARINI, J

Volltext

Potent antitumor activity of the acyclic nucleoside phosphonate 9‐(2‐phosphonylmethoxyethyl)adenine in choriocarcinoma‐bearing rats von Hatse, S., Naesens, L., Degrève, B., Segers, C., Vandeputte, M., Waer, M., De Clercq, E., Balzarini, J.

Volltext

Characterization of Multiple Nuclear Localization Signals in Herpes Simplex Virus Type 1 Thymidine Kinase von Degrève, Bart, Esnouf, Robert, De Clercq, Erik, Balzarini, Jan

Volltext

Cloning and Characterization of the Multisubstrate Deoxyribonucleoside Kinase of Drosophila melanogaster von Johansson, Magnus, Van Rompay, An R., Degrève, Bart, Balzarini, Jan, Karlsson, Anna

Volltext

Improving AZT efficacy von Balzarini, J, Degrève, B, De Clercq, E

Volltext

Varicella-zoster virus thymidine kinase gene and antiherpetic pyrimidine nucleoside analogues in a combined gene/chemotherapy treatment for cancer von DEGREVE, B, ANDREI, G, BALZARINI, J, IZQUIERDO, M, PIETTE, J, MORIN, K, KNAUS, E. E, WIEBE, L. I, BASRAH, I, WALKERS, R. T, DE CLERCQ, E

Volltext

Selection of HSV-1 TK gene-transfected murine mammary carcinoma cells resistant to (E)-5-(2-bromovinyl)-2'-deoxyuridine (BVDU) and ganciclovir (GCV) von DEGREVE, B, DE CLERCQ, E, BALZARINI, J

Volltext

Budding Yeast as a Screening Tool for Discovery of Nucleoside Analogs for Use in HSV-1 TK Suicide-Gene Therapy von Wera, S, Degrève, B, Balzarini, J, De Clercq, E, Thevelein, J.M, Neyts, J

Volltext

Comparative in vitro and in vivo cytotoxic activity of (E)-5-(2-bromovinyl)-2'-deoxyuridine (BVDU) and its arabinosyl derivative, (E)-5-(2-bromovinyl)-1-beta-D-arabinofuranosylurac... von Grignet-Debrus, C, Cool, V, Baudson, N, Degrève, B, Balzarini, J, De Leval, L, Debrus, S, Velu, T, Calberg-Bacq, C M

Volltext

The Multifunctional Deoxynucleoside Kinase of Insect Cells Is a Target for the Development of New Insecticides von Balzarini, J, Degrève, B, Hatse, S, De Clercq, E, Breuer, M, Johansson, M, Huybrechts, R, Karlsson, A

Volltext

Selective Abolishment of Pyrimidine Nucleoside Kinase Activity of Herpes Simplex Virus Type 1 Thymidine Kinase by Mutation of Alanine-167 to Tyrosine von Degrève, B, Esnouf, R, De Clercq, E, Balzarini, J

Volltext

Differential Intracellular Compartmentalization of Herpetic Thymidine Kinases (TKs) in TK Gene-Transfected Tumor Cells: Molecular Characterization of the Nuclear Localization Signa... von Degrève, B, Johansson, M, De Clercq, E, Karlsson, A, Balzarini, J

Volltext

Kinetic analysis of novel multisubstrate analogue inhibitors of thymidine phosphorylase von Balzarini, Jan, Degrève, Bart, Esteban-Gamboa, Antonio, Esnouf, Robert, De Clercq, Erik, Engelborghs, Yves, Camarasa, Maria-José, Pérez-Pérez, Maria-Jesús

Volltext

Mutation of Gln125 to Asn Selectively Abolishes the Thymidylate Kinase Activity of Herpes Simplex Virus Type 1 Thymidine Kinase von Bart Degrève, Robert Esnouf, Erik De Clercq, Jan Balzarini

Volltext

2′- O-Acyl/alkyl-substituted arabinosyl nucleosides as inhibitors of human mitochondrial thymidine kinase von Balzarinia, Jan, Degrève, Bart, Zhu, Chaoyong, Durini, Elisa, Porcu, Luca, De Clercq, Erik, Karlsson, Anna, Manfredini, Stefano

Volltext

Superior cytostatic activity of the ganciclovir elaidic acid ester due to the prolonged intracellular retention of ganciclovir anabolites in herpes simplex virus type 1 thymidine k... von BALZARINI, J, DEGREVE, B, ANDREI, G, NEYTS, J, SANDVOLD, M, MYHREN, F, DE CLERCQ, E

Volltext

Bystander effect of purine nucleoside analogues in HSV-1 tk suicide gene therapy is superior to that of pyrimidine nucleoside analogues von Degrève, B, De Clercq, E, Balzarini, J

Volltext

Crystal Structure of Varicella Zoster Virus Thymidine Kinase von Bird, Louise E, Ren, Jingshan, Wright, Alan, Leslie, Kris D, Degrève, Bart, Balzarini, Jan, Stammers, David K

Volltext

Potent antitumor activity of the differentiation-inducing agent 9-(2-phosphonylmethoxyethyl) adenine (PMEA) in choriocarcinoma-bearing rats von Hatse, S., Degrève, B., De Clercq, E., Vandeputte, M., Waer, M., Balzarini, J.

Volltext

Better preservation of the peritoneum in rats exposed to amino acid-based peritoneal dialysis fluid von Zareie, M, van Lambalgen, AA, ter Wee, PM, Hekking, LH, Keuning, ED, Schadee-Eestermans, IL, Faict, D, Degreve, B, Tangelder, GJ, Beelen, RH, van den Born, J

Volltext