Predictive Biomarkers of Sensitivity to the Phosphatidylinositol 3' Kinase Inhibitor GDC-0941 in Breast Cancer Preclinical Models von O'BRIEN, Carol, WALLIN, Jeffrey J, BEIVIN, Marcia, FRIEDMAN, Lori S, LACKNER, Mark R, SAMPATH, Deepak, GUHATHAKURTA, Debraj, SAVAGE, Heidi, PUNNOOSE, Elizabeth A, GUAN, Jane, BERRY, Leanne, PRIOR, Wei Wei, AMLER, Lukas C

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Mapping the genetic architecture of gene expression in human liver von Schadt, Eric E, Molony, Cliona, Chudin, Eugene, Hao, Ke, Yang, Xia, Lum, Pek Y, Kasarskis, Andrew, Zhang, Bin, Wang, Susanna, Suver, Christine, Zhu, Jun, Millstein, Joshua, Sieberts, Solveig, Lamb, John, GuhaThakurta, Debraj, Derry, Jonathan, Storey, John D, Avila-Campillo, Iliana, Kruger, Mark J, Johnson, Jason M, Rohl, Carol A, van Nas, Atila, Mehrabian, Margarete, Drake, Thomas A, Lusis, Aldons J, Smith, Ryan C, Guengerich, F Peter, Strom, Stephen C, Schuetz, Erin, Rushmore, Thomas H, Ulrich, Roger

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An integrative genomics approach to infer causal associations between gene expression and disease von Schadt, Eric E, Lamb, John, Yang, Xia, Zhu, Jun, Edwards, Steve, GuhaThakurta, Debraj, Sieberts, Solveig K, Monks, Stephanie, Reitman, Marc, Zhang, Chunsheng, Lum, Pek Yee, Leonardson, Amy, Thieringer, Rolf, Metzger, Joseph M, Yang, Liming, Castle, John, Zhu, Haoyuan, Kash, Shera F, Drake, Thomas A, Sachs, Alan, Lusis, Aldons J

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Elucidating the Role of Gonadal Hormones in Sexually Dimorphic Gene Coexpression Networks von van Nas, Atila, GuhaThakurta, Debraj, Wang, Susanna S, Yehya, Nadir, Horvath, Steve, Zhang, Bin, Ingram-Drake, Leslie, Chaudhuri, Gautam, Schadt, Eric E, Drake, Thomas A, Arnold, Arthur P, Lusis, Aldons J

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Identifying target sites for cooperatively binding factors von GuhaThakurta, Debraj, Stormo, Gary D.

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Identification of genes and networks driving cardiovascular and metabolic phenotypes in a mouse F2 intercross von Derry, Jonathan M J, Zhong, Hua, Molony, Cliona, MacNeil, Doug, Guhathakurta, Debraj, Zhang, Bin, Mudgett, John, Small, Kersten, El Fertak, Lahcen, Guimond, Alain, Selloum, Mohammed, Zhao, Wenqing, Champy, Marie France, Monassier, Laurent, Vogt, Tom, Cully, Doris, Kasarskis, Andrew, Schadt, Eric E

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Cis-regulatory variations: a study of SNPs around genes showing cis-linkage in segregating mouse populations von GuhaThakurta, Debraj, Xie, Tao, Anand, Manish, Edwards, Stephen W, Li, Guoya, Wang, Susanna S, Schadt, Eric E

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Computational identification of transcriptional regulatory elements in DNA sequence von GuhaThakurta, Debraj

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Exon and junction microarrays detect widespread mouse strain- and sex-bias expression differences von Su, Wan-Lin, Modrek, Barmak, GuhaThakurta, Debraj, Edwards, Stephen, Shah, Jyoti K, Kulkarni, Amit V, Russell, Archie, Schadt, Eric E, Johnson, Jason M, Castle, John C

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Humoral Immune Response against Nontargeted Tumor Antigens after Treatment with Sipuleucel-T and Its Association with Improved Clinical Outcome von GuhaThakurta, Debraj, Sheikh, Nadeem A, Fan, Li-Qun, Kandadi, Harini, Meagher, T Craig, Hall, Simon J, Kantoff, Philip W, Higano, Celestia S, Small, Eric J, Gardner, Thomas A, Bailey, Kate, Vu, Tuyen, DeVries, Todd, Whitmore, James B, Frohlich, Mark W, Trager, James B, Drake, Charles G

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A Randomized Phase II Trial of Sipuleucel-T with Concurrent versus Sequential Abiraterone Acetate plus Prednisone in Metastatic Castration-Resistant Prostate Cancer von Small, Eric J, Lance, Raymond S, Gardner, Thomas A, Karsh, Lawrence I, Fong, Lawrence, McCoy, Candice, DeVries, Todd, Sheikh, Nadeem A, GuhaThakurta, Debraj, Chang, Nancy, Redfern, Charles H, Shore, Neal D

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A comprehensive transcript index of the human genome generated using microarrays and computational approaches von Schadt, Eric E, Edwards, Stephen W, GuhaThakurta, Debraj, Holder, Dan, Ying, Lisa, Svetnik, Vladimir, Leonardson, Amy, Hart, Kyle W, Russell, Archie, Li, Guoya, Cavet, Guy, Castle, John, McDonagh, Paul, Kan, Zhengyan, Chen, Ronghua, Kasarskis, Andrew, Margarint, Mihai, Caceres, Ramon M, Johnson, Jason M, Armour, Christopher D, Garrett-Engele, Philip W, Tsinoremas, Nicholas F, Shoemaker, Daniel D

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Inactivation of TP53 correlates with disease progression and low miR-34a expression in previously treated chronic lymphocytic leukemia patients von Dufour, Annika, Palermo, Giuseppe, Zellmeier, Evelyn, Mellert, Gudrun, Duchateau-Nguyen, Guillemette, Schneider, Stephanie, Benthaus, Tobias, Kakadia, Purvi M., Spiekermann, Karsten, Hiddemann, Wolfgang, Braess, Jan, Truong, Sim, Patten, Nancy, Wu, Lin, Lohmann, Sabine, Dornan, David, GuhaThakurta, Debraj, Yeh, Ru-Fang, Salogub, Galina, Solal-Celigny, Philippe, Dmoszynska, Anna, Robak, Tadeusz, Montillo, Marco, Catalano, John, Geisler, Christian H., Weisser, Martin, Bohlander, Stefan K.

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Changes in circulating and intratumoral T cell clonotypes in sipuleucel-T-treated prostate cancer patients von Fong, Lawrence, Cham, Jason, Zhang, Li, DeVries, Todd, Pufnock, Jeff, GuhaThakurta, Debraj, Letarte, Simon, Hamm, David, Trager, James B., Sheikh, Nadeem A.

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Conserved homeodomain proteins interact with MADS box protein Mcm1 to restrict ECB-dependent transcription to the M/G1 phase of the cell cycle von Pramila, Tata, Miles, Shawna, GuhaThakurta, Debraj, Jemiolo, Dave, Breeden, Linda L

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Abstract 2542: Sipuleucel-T-induced immune response against secondary cancer antigens is associated with improved overall survival von GuhaThakurta, Debraj, Fan, Li-Qun, Vu, Tuyen, Stewart, Francis, Kantoff, Philip, Small, Eric, Higano, Celeste, Gardner, Thomas, Sheikh, Nadeem, Trager, James

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Antigen spread and survival with sipuleucel-T in patients with advanced prostate cancer von Drake, Charles G., Fan, Li-Qun, GuhaThakurta, Debraj, Stewart, Frances, Kantoff, Philip W., Small, Eric Jay, Gardner, Thomas A., Sheikh, Nadeem A., Trager, James B., Higano, Celestia S.

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Identification of a novel cis-regulatory element involved in the heat shock response in Caenorhabditis elegans using microarray gene expression and computational methods von GuhaThakurta, Debraj, Palomar, Lisanne, Stormo, Gary D, Tedesco, Pat, Johnson, Thomas E, Walker, David W, Lithgow, Gordon, Kim, Stuart, Link, Christopher D

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Induction of antigen spread after sipuleucel-T treatment and its association with improved clinical outcome von GuhaThakurta, Debraj, Fan, Li-Qun, Vu, Tuyen, Sheikh, Nadeem A, Trager, James B

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Novel transcription regulatory elements in Caenorhabditis elegans muscle genes von GuhaThakurta, Debraj, Schriefer, Lawrence A, Waterston, Robert H, Stormo, Gary D

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