Perturbations of the AKT signaling pathway in human cancer von Altomare, Deborah A, Testa, Joseph R

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PD-L1 blockade enhances anti-tumor efficacy of NK cells von Oyer, Jeremiah L., Gitto, Sarah B., Altomare, Deborah A., Copik, Alicja J.

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Pancreatic Ductal Adenocarcinoma (PDAC) circulating tumor cells influence myeloid cell differentiation to support their survival and immunoresistance in portal vein circulation von Arnoletti, Juan Pablo, Reza, Joseph, Rosales, Armando, Monreal, Alberto, Fanaian, Na'im, Whisner, Suzanne, Srivastava, Milan, Rivera-Otero, Julia, Yu, Gongxin, Phanstiel Iv, Otto, Altomare, Deborah A, Tran, Quang, Litherland, Sally A

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Development and validation of a LC–MS/MS assay for quantification of cisplatin in rat plasma and urine von Shaik, Abdul Naveed, Altomare, Deborah A., Lesko, Lawrence J., Trame, Mirjam N.

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Differential Expression of Polyamine Pathways in Human Pancreatic Tumor Progression and Effects of Polyamine Blockade on Tumor Microenvironment von Nakkina, Sai Preethi, Gitto, Sarah B, Pandey, Veethika, Parikh, Jignesh G, Geerts, Dirk, Maurer, Hans Carlo, Olive, Kenneth P, Phanstiel, 4th, Otto, Altomare, Deborah A

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Cryopreserved PM21-Particle-Expanded Natural Killer Cells Maintain Cytotoxicity and Effector Functions In Vitro and In Vivo von Oyer, Jeremiah L, Croom-Perez, Tayler J, Dieffenthaller, Thomas A, Robles-Carillo, Liza D, Gitto, Sarah B, Altomare, Deborah A, Copik, Alicja J

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RAD001 Inhibits Human Ovarian Cancer Cell Proliferation, Enhances Cisplatin-Induced Apoptosis, and Prolongs Survival in an Ovarian Cancer Model von Mabuchi, Seiji, Altomare, Deborah A, Cheung, Mitchell, Zhang, Lili, Poulikakos, Poulikos I, Hensley, Harvey H, Schilder, Russell J, Ozols, Robert F, Testa, Joseph R

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mTOR Is a Promising Therapeutic Target Both in Cisplatin-Sensitive and Cisplatin-Resistant Clear Cell Carcinoma of the Ovary von MABUCHI, Seiji, KAWASE, Chiaki, OHMICHI, Masahide, TESTA, Joseph R, KIMURA, Tadashi, ALTOMARE, Deborah A, MORISHIGE, Kenichirou, SAWADA, Kenjiro, HAYASHI, Masami, TSUJIMOTO, Masahiko, YAMOTO, Mareo, KLEIN-SZANTO, Andres J, SCHILDER, Russell J

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FAS-Associated Factor 1 (FAF1): Diverse functions and implications for oncogenesis von Menges, Craig W., Altomare, Deborah A., Testa, Joseph R.

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PM21-particle stimulation augmented with cytokines enhances NK cell expansion and confers memory-like characteristics with enhanced survival von Oyer, Jeremiah L, Croom-Perez, Tayler J, Hasan, Md Faqrul, Rivera-Huertas, Javier A, Gitto, Sarah B, Mucha, Joanna M, Zhu, Xiang, Altomare, Deborah A, Igarashi, Robert Y, Copik, Alicja J

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Losses of both products of the Cdkn2a/Arf locus contribute to asbestos-induced mesothelioma development and cooperate to accelerate tumorigenesis von Altomare, Deborah A, Menges, Craig W, Xu, Jinfei, Pei, Jianming, Zhang, Lili, Tadevosyan, Ara, Neumann-Domer, Erin, Liu, Zemin, Carbone, Michele, Chudoba, Ilse, Klein-Szanto, Andres J, Testa, Joseph R

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Phase II Study of Erlotinib in Patients With Malignant Pleural Mesothelioma: A Southwest Oncology Group Study von GARLAND, Linda L, RANKIN, Cathryn, GANDARA, David R, RIVKIN, Saul E, SCOTT, Katherine M, NAGLE, Raymond B, KLEIN-SZANTO, Andres J. P, TESTA, Joseph R, ALTOMARE, Deborah A, BORDEN, Ernest C

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RAD001 (everolimus) delays tumor onset and progression in a transgenic mouse model of ovarian cancer von MABUCHI, Seiji, ALTOMARE, Deborah A, CONNOLLY, Denise C, KLEIN-SZANTO, Andres, LITWIN, Samuel, HOELZLE, Matthew K, HENSLEY, Harvey H, HAMILTON, Thomas C, TESTA, Joseph R

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Identification of a novel IL-5 signaling pathway in chronic pancreatitis and crosstalk with pancreatic tumor cells von Gitto, Sarah B, Beardsley, Jordan M, Nakkina, Sai Preethi, Oyer, Jeremiah L, Cline, Kathryn A, Litherland, Sally A, Copik, Alicja J, Khaled, Amr S, Fanaian, Na'im, Arnoletti, J Pablo, Altomare, Deborah A

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Vascular endothelial growth factor is a promising therapeutic target for the treatment of clear cell carcinoma of the ovary von Mabuchi, Seiji, Kawase, Chiaki, Altomare, Deborah A, Morishige, Kenichirou, Hayashi, Masami, Sawada, Kenjiro, Ito, Kimihiko, Terai, Yoshito, Nishio, Yukihiro, Klein-Szanto, Andres J, Burger, Robert A, Ohmichi, Masahide, Testa, Joseph R, Kimura, Tadashi

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Appl1 Is Dispensable for Mouse Development, and Loss of Appl1 Has Growth Factor-selective Effects on Akt Signaling in Murine Embryonic Fibroblasts von Tan, Yinfei, You, Huihong, Wu, Chao, Altomare, Deborah A., Testa, Joseph R.

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Synthesis and Biological Evaluation of Antimetastatic Agents Predicated upon Dihydromotuporamine C and Its Carbocyclic Derivatives von Muth, Aaron, Pandey, Veethika, Kaur, Navneet, Wason, Melissa, Baker, Cheryl, Han, Xianlin, Johnson, Teresa R, Altomare, Deborah A, Phanstiel, Otto

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Positive feedback regulation between AKT activation and fatty acid synthase expression in ovarian carcinoma cells von Wang, Hui Qin, Altomare, Deborah A, Skele, Kristine L, Poulikakos, Poulikos I, Kuhajda, Francis P, Di Cristofano, Antonio, Testa, Joseph R

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Activated TNF-α/NF-κB signaling via down-regulation of Fas-associated factor 1 in asbestos-induced mesotheliomas from Arf knockout mice von Altomare, Deborah A, Menges, Craig W, Pei, Jianming, Zhang, Lili, Skele-Stump, Kristine L, Carbone, Michele, Kane, Agnes B, Testa, Joseph R

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The NF2 Tumor Suppressor Gene Product, Merlin, Inhibits Cell Proliferation and Cell Cycle Progression by Repressing Cyclin D1 Expression von Xiao, Guang-Hui, Gallagher, Ryan, Shetler, Justin, Skele, Kristine, Altomare, Deborah A., Pestell, Richard G., Jhanwar, Suresh, Testa, Joseph R.

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