Cancer associated fibroblasts promote tumor growth and metastasis by modulating the tumor immune microenvironment in a 4T1 murine breast cancer model von Liao, Debbie, Luo, Yunping, Markowitz, Dorothy, Xiang, Rong, Reisfeld, Ralph A

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Tumor‐Associated Macrophages Regulate Murine Breast Cancer Stem Cells Through a Novel Paracrine EGFR/Stat3/Sox‐2 Signaling Pathway von Yang, Jian, Liao, Debbie, Chen, Cong, Liu, Yan, Chuang, Tsung‐Hsien, Xiang, Rong, Markowitz, Dorothy, Reisfeld, Ralph A., Luo, Yunping

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EGF816 Exerts Anticancer Effects in Non-Small Cell Lung Cancer by Irreversibly and Selectively Targeting Primary and Acquired Activating Mutations in the EGF Receptor von Jia, Yong, Juarez, Jose, Li, Jie, Manuia, Mari, Niederst, Matthew J, Tompkins, Celin, Timple, Noelito, Vaillancourt, Mei-Ting, Pferdekamper, AnneMarie Culazzo, Lockerman, Elizabeth L, Li, Chun, Anderson, Jennifer, Costa, Carlotta, Liao, Debbie, Murphy, Eric, DiDonato, Michael, Bursulaya, Badry, Lelais, Gerald, Barretina, Jordi, McNeill, Matthew, Epple, Robert, Marsilje, Thomas H, Pathan, Nuzhat, Engelman, Jeffrey A, Michellys, Pierre-Yves, McNamara, Peter, Harris, Jennifer, Bender, Steven, Kasibhatla, Shailaja

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Transcriptional Repression of Atherogenic Inflammation: Modulation by PPARδ von Lee, Chih-Hao, Chawla, Ajay, Urbiztondo, Ned, Liao, Debbie, Boisvert, William A., Evans, Ronald M., Curtiss, Linda K.

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Adipose-specific peroxisome proliferator-activated receptor gamma knockout causes insulin resistance in fat and liver but not in muscle von He, W, Barak, Y, Hevener, A, Olson, P, Liao, D, Le, J, Nelson, M, Ong, E, Olefsky, J.M, Evans, R.M

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Targeted Therapeutic Remodeling of the Tumor Microenvironment Improves an HER-2 DNA Vaccine and Prevents Recurrence in a Murine Breast Cancer Model von DEBBIE LIAO, ZE LIU, WRASIDLO, Wolfgang J, YUNPING LUO, NGUYEN, Giang, TINGMEI CHEN, RONG XIANG, REISFELD, Ralph A

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Effects of Peroxisome Proliferator-Activated Receptor δ on Placentation, Adiposity, and Colorectal Cancer von Barak, Yaacov, Liao, Debbie, He, Weimin, Ong, Estelita S., Nelson, Michael C., Olefsky, Jerrold M., Boland, Richard, Evans, Ronald M.

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PPARδ Is a Very Low-Density Lipoprotein Sensor in Macrophages von Chawla, Ajay, Lee, Chih-Hao, Barak, Yaacov, He, Weimin, Rosenfeld, John, Liao, Debbie, Han, Jungyeob, Kang, Heonjoong, Evans, Ronald M.

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Synthetic enzyme inhibitor: a novel targeting ligand for nanotherapeutic drug delivery inhibiting tumor growth without systemic toxicity von Liao, Debbie, PhD, Liu, Ze, BS, Wrasidlo, Wolfgang, PhD, Chen, Tingmei, PhD, Luo, Yunping, MD, PhD, Xiang, Rong, MD, PhD, Reisfeld, Ralph A., PhD

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Hypoxia: a key regulator of angiogenesis in cancer von Liao, Debbie, Johnson, Randall S

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Hypoxia-inducible factor-1α is a key regulator of metastasis in a transgenic model of cancer initiation and progression von LIAO, Debbie, CORLE, Courtney, SEAGROVES, Tiffany N, JOHNSON, Randall S

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Abstract CC07-01: Whole exome and whole genome methylation sequencing of low-input cfDNA to implement precision medicine in metastatic castration resistant prostate cancer von Kandimalla, Raju, Xiang, Binggang, Dai, Chao, Wang, Amy, Du, Pan, Luo, Shujun, Liao, Debbie

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Macrophage Expression of Hypoxia-Inducible Factor-1α Suppresses T-Cell Function and Promotes Tumor Progression von DOEDENS, Andrew L, STOCKMANN, Christian, RUBINSTEIN, Mark P, LIAO, Debbie, NA ZHANG, DENARDO, David G, COUSSENS, Lisa M, KARIN, Michael, GOLDRATH, Ananda W, JOHNSON, Randall S

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Endothelial Cell HIF-1α and HIF-2α Differentially Regulate Metastatic Success von Branco-Price, Cristina, Zhang, Na, Schnelle, Moritz, Evans, Colin, Katschinski, Dörthe M., Liao, Debbie, Ellies, Lesley, Johnson, Randall S.

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PPAR-γ dependent and independent effects on macrophage-gene expression in lipid metabolism and inflammation von Chawla, Ajay, Barak, Yaacov, Nagy, Laszlo, Liao, Debbie, Tontonoz, Peter, Evans, Ronald M.

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Abstract B092: Intrinsic genomic plasticity of extrachromosomal DNA (ecDNA) enables oncogene amplified tumor cells to develop rapid acquired resistance to targeted therapy von Turner, Kristen, Hemmati, Homa, DuPai, Cory, Bibay, John, Klebs, Claire, Chen, Joan, Liao, Debbie, Hassig, Christian, Kasibhatla, Shailaja

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The role of proto-oncogene Fra-1 in remodeling the tumor microenvironment in support of breast tumor cell invasion and progression von Luo, Y P, Zhou, H, Krueger, J, Kaplan, C, Liao, D, Markowitz, D, Liu, C, Chen, T, Chuang, T -H, Xiang, R, Reisfeld, R A

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A PPARγ-LXR-ABCA1 Pathway in Macrophages Is Involved in Cholesterol Efflux and Atherogenesis von Chawla, Ajay, Boisvert, William A., Lee, Chih-Hao, Laffitte, Bryan A., Barak, Yaacov, Joseph, Sean B., Liao, Debbie, Nagy, Laszlo, Edwards, Peter A., Curtiss, Linda K., Evans, Ronald M., Tontonoz, Peter

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Ralph A. Reisfeld, PhD: In Memoriam (1926–2020) von Allison, James P., Barker, Edward, Becker, Jürgen C., Bumol, Thomas F., Cheresh, David, Church, Bill, Ferrone, Soldano, Galloway, Darrell R., Giedlin, Martin, Gillies, Stephen, Handgretinger, Rupert, Harper, John R., Imai, Kohzoh, Kahan, Barry, Ladenstein, Ruth, Liao, Debbie, Lode, Holger N., Loibner, Hans, Luo, Yun-Ping, Mueller, Barbara M., Ng, AhKau, Niethammer, Andreas, Pellegrino, Michele, Pertl, Ursula, Quaranta, Vito, Russo, Carlo, Sabzevari, Helen, Schrappe, Martin, Schulz, Gregor, Sondel, Paul, Stahl, Andreas, Theophilopoulos, Argyrios, Varki, Nissi, Walker, Leslie, Wilson, Barry, Wrasidlo, Wolfgang, Wargalla-Plate, Ursula, Xiang, Rong, Yu, Alice, Zhou, He

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Abstract 3366: An inhibitor of the NF-kappaB pathway targets cancer stem cells and prevents tumor recurrence von Gomez-Cabrero, Azucena, Liao, Debbie, Nguyen, Giang, Reisfeld, Ralph

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