Cognitive function trajectories and their determinants in older people: 8 years of follow-up in the English Longitudinal Study of Ageing von Zaninotto, P, Batty, D, Allerhand, M, Deary, JI

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Improved precision of epigenetic clock estimates across tissues and its implication for biological ageing von Zhang, Qian, Vallerga, Costanza L, Walker, Rosie M, Lin, Tian, Henders, Anjali K, Montgomery, Grant W, He, Ji, Fan, Dongsheng, Fowdar, Javed, Kennedy, Martin, Pitcher, Toni, Pearson, John, Halliday, Glenda, Kwok, John B, Hickie, Ian, Lewis, Simon, Anderson, Tim, Silburn, Peter A, Mellick, George D, Harris, Sarah E, Redmond, Paul, Murray, Alison D, Porteous, David J, Haley, Christopher S, Evans, Kathryn L, McIntosh, Andrew M, Yang, Jian, Gratten, Jacob, Marioni, Riccardo E, Wray, Naomi R, Deary, Ian J, McRae, Allan F, Visscher, Peter M

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Deciphering colorectal cancer genetics through multi-omic analysis of 100,204 cases and 154,587 controls of European and east Asian ancestries von Fernandez-Rozadilla, Ceres, Chen, Zhishan, Law, Philip, Thomas, Minta, Díez-Obrero, Virginia, Hsu, Li, Fernandez-Tajes, Juan, Svinti, Victoria, Donnelly, Kevin, Farrington, Susan, Lu, Yingchang, Broderick, Peter, Conti, David, Devall, Mathew, Schumacher, Fredrick, Melas, Marilena, Rennert, Gad, Obón-Santacana, Mireia, Martín-Sánchez, Vicente, Shin, Min-Ho, Shin, Aesun, Kim, Dong-Hyun, Oze, Isao, Tanikawa, Chizu, Ren, Zefang, Gao, Yu-Tang, Jenkins, Mark, Figueiredo, Jane, Gallinger, Steven, Woods, Michael, Newcomb, Polly, Duggan, David, Maughan, Timothy, Kerr, Rachel, Mecklin, Lukka-Pekka, Jousilahti, Pekka, Aaltonen, Lauri, Rissanen, Harri, Eriksson, Johan, Cajuso, Tatiana, Palin, Kimmo, Tanskanen, Tomas, Renkonen-Sinisalo, Laura, Albanes, Demetrius, Weinstein, Stephanie, Platz, Elizabeth, Siegel, Erin, Brezina, Stefanie, Gsur, Andrea, Campbell, Peter, Chang-Claude, Jenny, Castellví-Bel, Sergi, Arndt, Volker, Bishop, Timothy, Idos, Gregory, McDonnell, Kevin, Abu-Ful, Zomoroda, Lejbkowicz, Flavio, Offit, Kenneth, Steinfelder, Robert, van Guelpen, Bethany, Hudson, Thomas, Berndt, Sonja, Hayes, Richard, Pharoah, Paul, Larsson, Susanna, Yen, Yun, Lenz, Heinz-Josef, White, Emily, Li, Li, Pugh, Elizabeth, Cruz-Correa, Marcia, Hunter, David, Nickerson, Deborah, Schoen, Robert, Hampe, Jochen, Edlund, Chistopher, Gauderman, William, Shibata, David, van Duijnhoven, Franzel, Feskens, Edith, Wolk, Alicja, Naccarati, Alessio, Lee, Soo Chin, Bien, Stephanie, Lin, Yi, Bézieau, Stéphane, Tangen, Catherine, Mardis, Elaine, Sawada, Norie, Iwasaki, Motoki, Coetzee, Gerhard, Hayward, Caroline, Deary, Ian, Harris, Sarah, Reid, Stuart, Walker, Marion, Ooi, Li Yin, Zheng, Wei, Peters, Ulrike

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Fine-mapping analysis including over 254,000 East Asian and European descendants identifies 136 putative colorectal cancer susceptibility genes von Tao, Ran, Law, Philip J., Jia, Guochong, Long, Jirong, Li, Chao, Timofeeva, Maria N., Schmit, Stephanie L., Devall, Matthew, Moratalla-Navarro, Ferran, Fernandez-Tajes, Juan, Palles, Claire, Donnelly, Kevin, Vaughan-Shaw, Peter G., Shu, Xiao-Ou, Lu, Yingchang, Broderick, Peter, Conti, David V., Obón-Santacana, Mireia, Martín-Sánchez, Vicente, Shin, Min-Ho, Kim, Dong-Hyun, Oze, Isao, Tanikawa, Chizu, Ren, Zefang, Gao, Yu-Tang, Win, Aung Ko, Pai, Rish K., Haile, Robert W., Woods, Michael O., Newcomb, Polly A., Duggan, David, Cheadle, Jeremy P., Kaplan, Richard, Kerr, Rachel, Kerr, David, Kirac, Iva, Aaltonen, Lauri A., Rissanen, Harri, Cajuso, Tatiana, Palin, Kimmo, Tanskanen, Tomas, Männistö, Satu, Weinstein, Stephanie J., Ruiz-Narvaez, Edward, Palmer, Julie R., Buchanan, Daniel D., Platz, Elizabeth A., Visvanathan, Kala, Ulrich, Cornelia M., Siegel, Erin, Brezina, Stefanie, Gsur, Andrea, Castells, Antoni, Castellví-Bel, Sergi, Moreira, Leticia, Arndt, Volker, Giles, Graham G., Abu-Ful, Zomoroda, Greenson, Joel K., Shulman, Katerina, Offit, Kenneth, Keku, Temitope O., van Guelpen, Bethany, Berndt, Sonja I., Larsson, Susanna C., White, Emily, Pugh, Elizabeth, Chan, Andrew T., Hunter, David J., Schafmayer, Clemens, Scacheri, Peter C., Hampe, Jochen, Gauderman, W. James, Shibata, David, Toland, Amanda, Markowitz, Sanford, van Duijnhoven, Franzel, Feskens, Edith J. M., FitzGerald, Liesel M., Ogino, Shuji, Bien, Stephanie A., Kooperberg, Charles, Li, Christopher I., Prentice, Ross, Bézieau, Stéphane, Yamaji, Taiki, Le Marchand, Loic, Qu, Chenxu, Deary, Ian J., Harris, Sarah E., Walker, Marion, Ooi, Li Yin, Lau, Ken S., Hsu, Li, Dunlop, Malcolm G., Gruber, Stephen B., Moreno, Victor, Casey, Graham, Peters, Ulrike, Tomlinson, Ian

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Comparison of HapMap and 1000 Genomes Reference Panels in a Large-Scale Genome-Wide Association Study von De Vries, PS, Sabater-Lleal, M, Chasman, DI, Trompet, S, Ahluwalia, TS, Teumer, A, Kleber, ME, Chen, M-H, Wang, JJ, Attia, JR, Marioni, RE, Steri, M, Weng, L-C, Pool, R, Grossmann, V, Brody, JA, Venturini, C, Tanaka, T, Rose, LM, Oldmeadow, C, Mazur, J, Basu, S, Franberg, M, Yang, Q, Ligthart, S, Hottenga, JJ, Rumley, A, Mulas, A, De Craen, AJM, Grotevendt, A, Taylor, KD, Delgado, GE, Kifley, A, Lopez, LM, Berentzen, TL, Mangino, M, Bandinelli, S, Morrison, AC, Hamsten, A, Tofler, G, De Maat, MPM, Draisma, HHM, Lowe, GD, Zoledziewska, M, Sattar, N, Lackner, KJ, Voelker, U, McKnight, B, Huang, J, Holliday, EG, McEvoy, MA, Starr, JM, Hysi, PG, Hernandez, DG, Guan, W, Rivadeneira, F, McArdle, WL, Slagboom, PE, Zeller, T, Psaty, BM, Uitterlinden, AG, De Geus, EJC, Stott, DJ, Binder, H, Hofman, A, Franco, OH, Rotter, JI, Ferrucci, L, Spector, TD, Deary, IJ, Maerz, W, Greinacher, A, Wild, PS, Cucca, F, Boomsma, DI, Watkins, H, Tang, W, Ridker, PM, Jukema, JW, Scott, RJ, Mitchell, P, Hansen, T, O'Donnell, CJ, Smith, NL, Strachan, DP, Dehghan, A

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Large-scale exome-wide association analysis identifies loci for white blood cell traits and pleiotropy with immune-mediated diseases von Tajuddin, SM, Schick, UM, Eicher, JD, Chami, N, Giri, A, Brody, JA, Hill, WD, Kacprowski, T, Li, J, Lyytikäinen, LP, Manichaikul, A, Mihailov, E, O'Donoghue, ML, Pankratz, N, Pazoki, R, Polfus, LM, Smith, AV, Schurmann, C, Vacchi-Suzzi, C, Waterworth, DM, Evangelou, E, Yanek, LR, Burt, A, Chen, MH, Van Rooij, FJ, Floyd, JS, Greinacher, A, Harris, TB, Highland, HM, Lange, LA, Liu, Y, Mägi, R, Nalls, MA, Mathias, RA, Nickerson, DA, Nikus, K, Starr, JM, Tardif, JC, Tzoulaki, I, Velez Edwards, DR, Wallentin, L, Bartz, TM, Becker, LC, Denny, JC, Raffield, LM, Rioux, JD, Friedrich, N, Fornage, M, Gao, H, Hirschhorn, JN, Liewald, DC, Rich, SS, Uitterlinden, A, Bastarache, L, Becker, DM, Boerwinkle, E, De Denus, S, Bottinger, EP, Hayward, C, Hofman, A, Homuth, G, Lange, E, Launer, LJ, Lehtimäki, T, Lu, Y, Metspalu, A, O'Donnell, CJ, Quarells, RC, Richard, M, Torstenson, ES, Taylor, KD, Vergnaud, AC, Zonderman, AB, Crosslin, DR, Deary, IJ, Dörr, M, Elliott, P, Evans, MK, Gudnason, V, Kähönen, M, Psaty, BM, Rotter, JI, Slater, AJ, Dehghan, A, White, HD, Ganesh, SK, Loos, RJ, Esko, T, Faraday, N, Wilson, JG, Cushman, M, Johnson, AD, Edwards, TL, Zakai, NA, Lettre, G, Reiner, AP, Auer, PL

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A meta-analysis of thyroid-related traits reveals novel loci and gender-specific differences in the regulation of thyroid function von Porcu, E, Medici, M, Pistis, G, Volpato, CB, Wilson, SG, Cappola, AR, Bos, SD, Deelen, J, Den Heijer, M, Freathy, RM, Lahti, J, Liu, C, Lopez, LM, Nolte, IM, O'Connell, JR, Tanaka, T, Trompet, S, Arnold, A, Bandinelli, S, Beekman, M, Böhringer, S, Brown, SJ, Buckley, BM, Camaschella, C, De Craen, AJ, Davies, G, De Visser, MC, Ford, I, Forsen, T, Frayling, TM, Fugazzola, L, Gögele, M, Hattersley, AT, Hermus, AR, Hofman, A, Houwing-Duistermaat, JJ, Jensen, RA, Kajantie, E, Kloppenburg, M, Lim, EM, Masciullo, C, Mariotti, S, Minelli, C, Mitchell, BD, Nagaraja, R, Netea-Maier, RT, Palotie, A, Persani, L, Piras, MG, Psaty, BM, Räikkönen, K, Richards, JB, Rivadeneira, F, Sala, C, Sabra, MM, Sattar, N, Shields, BM, Soranzo, N, Starr, JM, Stott, DJ, Sweep, FC, Usala, G, Van der Klauw, MM, Van Heemst, D, Van Mullem, A, Vermeulen, SH, Visser, WE, Walsh, JP, Westendorp, RG, Widen, E, Zhai, G, Cucca, F, Deary, IJ, Eriksson, JG, Ferrucci, L, Fox, CS, Jukema, JW, Kiemeney, LA, Pramstaller, PP, Schlessinger, D, Shuldiner, AR, Slagboom, EP, Uitterlinden, AG, Vaidya, B, Visser, TJ, Wolffenbuttel, BH, Meulenbelt, I, Rotter, JI, Spector, TD, Hicks, AA, Toniolo, D, Sanna, S, Peeters, RP, Naitza, S

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Genetic correlations and genome-wide associations of cortical structure in general population samples of 22,824 adults von Hofer, E, Roshchupkin, GV, Adams, HHH, Knol, MJ, Lin, H, Li, S, Zare, H, Ahmad, S, Armstrong, NJ, Satizabal, CL, Bernard, M, Bis, JC, Gillespie, NA, Luciano, M, Mishra, A, Scholz, M, Teumer, A, Xia, R, Jian, X, Mosley, TH, Saba, Y, Pirpamer, L, Seiler, S, Becker, JT, Carmichael, O, Rotter, JI, Psaty, BM, Lopez, OL, Amin, N, van der Lee, SJ, Yang, Q, Himali, JJ, Maillard, P, Beiser, AS, DeCarli, C, Karama, S, Lewis, L, Harris, M, Bastin, ME, Deary, IJ, Veronica Witte, A, Beyer, F, Loeffler, M, Mather, KA, Schofield, PR, Thalamuthu, A, Kwok, JB, Wright, MJ, Ames, D, Trollor, J, Jiang, J, Brodaty, H, Wen, W, Vernooij, MW, Hofman, A, Uitterlinden, AG, Niessen, WJ, Wittfeld, K, Bülow, R, Völker, U, Pausova, Z, Bruce Pike, G, Maingault, S, Crivello, F, Tzourio, C, Amouyel, P, Mazoyer, B, Neale, MC, Franz, CE, Lyons, MJ, Panizzon, MS, Andreassen, OA, Dale, AM, Logue, M, Grasby, KL, Jahanshad, N, Painter, JN, Colodro-Conde, L, Bralten, J, Hibar, DP, Lind, PA, Pizzagalli, F, Stein, JL, Thompson, PM, Medland, SE, Ching, CRK, McMahon, MAB, Shatokhina, N, Zsembik, LCP, Agartz, I, Alhusaini, S, Almeida, MAA

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Genome-wide association study of 23,500 individuals identifies 7 loci associated with brain ventricular volume von Vojinovic, D, Adams, HH, Jian, X, Yang, Q, Smith, AV, Bis, JC, Teumer, A, Scholz, M, Armstrong, NJ, Hofer, E, Saba, Y, Luciano, M, Bernard, M, Trompet, S, Yang, J, Gillespie, NA, van der Lee, SJ, Neumann, A, Ahmad, S, Andreassen, OA, Ames, D, Amin, N, Arfanakis, K, Bastin, ME, Becker, DM, Beiser, AS, Beyer, F, Brodaty, H, Bryan, RN, Bülow, R, Dale, AM, De Jager, PL, Deary, IJ, DeCarli, C, Fleischman, DA, Gottesman, RF, van der Grond, J, Gudnason, V, Harris, TB, Homuth, G, Knopman, DS, Kwok, JB, Lewis, CE, Li, S, Loeffler, M, Lopez, OL, Maillard, P, El Marroun, H, Mather, KA, Mosley, TH, Muetzel, RL, Nauck, M, Nyquist, PA, Panizzon, MS, Pausova, Z, Psaty, BM, Rice, K, Rotter, JI, Royle, N, Satizabal, CL, Schmidt, R, Schofield, PR, Schreiner, PJ, Sidney, S, Stott, DJ, Thalamuthu, A, Uitterlinden, AG, Valdés Hernández, MC, Vernooij, MW, Wen, W, White, T, Witte, AV, Wittfeld, K, Wright, MJ, Yanek, LR, Tiemeier, H, Kremen, WS, Bennett, DA, Jukema, JW, Paus, T, Wardlaw, JM, Schmidt, H, Sachdev, PS, Villringer, A, Grabe, HJ, Longstreth, WT, van Duijn, CM, Launer, LJ, Seshadri, S, Ikram, MA, Fornage, M

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Comparison of HapMap and 1000 Genomes Reference Panels in a Large-Scale Genome-Wide Association Study von de Vries, PS, Sabater-Lleal, M, Chasman, DI, Trompet, S, Ahluwalia, TS, Teumer, A, Kleber, ME, Chen, M-H, Wang, JJ, Attia, JR, Marioni, RE, Steri, M, Weng, L-C, Pool, R, Grossmann, V, Brody, JA, Venturini, C, Tanaka, T, Rose, LM, Oldmeadow, C, Mazur, J, Basu, S, Franberg, M, Yang, Q, Ligthart, S, Hottenga, JJ, Rumley, A, Mulas, A, de Craen, AJM, Grotevendt, A, Taylor, KD, Delgado, GE, Kifley, A, Lopez, LM, Berentzen, TL, Mangino, M, Bandinelli, S, Morrison, AC, Hamsten, A, Tofler, G, de Maat, MPM, Draisma, HHM, Lowe, GD, Zoledziewska, M, Sattar, N, Lackner, KJ, Voelker, U, McKnight, B, Huang, J, Holliday, EG, McEvoy, MA, Starr, JM, Hysi, PG, Hernandez, DG, Guan, W, Rivadeneira, F, McArdle, WL, Slagboom, PE, Zeller, T, Psaty, BM, Uitterlinden, AG, de Geus, EJC, Stott, DJ, Binder, H, Hofman, A, Franco, OH, Rotter, JI, Ferrucci, L, Spector, TD, Deary, IJ, Maerz, W, Greinacher, A, Wild, PS, Cucca, F, Boomsma, DI, Watkins, H, Tang, W, Ridker, PM, Jukema, JW, Scott, RJ, Mitchell, P, Hansen, T, O'Donnell, CJ, Smith, NL, Strachan, DP, Dehghan, A

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Improved precision of epigenetic clock estimates across tissues and its implication for biological ageing von Zhang, Qian, Vallerga, Costanza L, Walker, Rosie M, Lin, Tian, Henders, Anjali K, Montgomery, Grant W, He, Ji, Fan, Dongsheng, Fowdar, Javed, Kennedy, Ma, Pitcher, Toni, Pearson, John, Halliday, Glenda, Kwok, John B, Hickie, Ian, Lewis, Simon, Anderson, Tim, Silburn, Peter A, Mellick, George D, Harris, Sarah E, Redmond, Paul, Murray, Alison D, Porteous, David J, Haley, Christopher S, Evans, Kathryn L, McIntosh, Andrew M, Yang, Jian, Gratten, Jacob, Marioni, Riccardo E, Wray, Naomi R, Deary, Ian J, McRae, Allan F, Visscher, Peter M

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Meta-analysis of rare and common exome chip variants identifies S1PR4 and other loci influencing blood cell traits von Pankratz, N, Schick, UM, Zhou, Y, Zhou, W, Ahluwalia, TS, Allende, ML, Auer, PL, Bork-Jensen, J, Brody, JA, Chen, M-H, Clavo, V, Eicher, JD, Grarup, N, Hagedorn, EJ, Hu, B, Hunker, K, Johnson, AD, Leusink, M, Lu, Y, Lyytikainen, L-P, Manichaikul, A, Marioni, RE, Nalls, MA, Pazoki, R, Smith, AV, van Rooij, FJA, Yang, M-L, Zhang, X, Zhang, Y, Asselbergs, FW, Boerwinkle, E, Borecki, IB, Bottinger, EP, Cushman, M, de Bakker, PIW, Deary, IJ, Dong, L, Feitosa, MF, Floyd, JS, Franceschini, N, Franco, OH, Garcia, ME, Grove, ML, Gudnason, V, Hansen, T, Harris, TB, Hofman, A, Jackson, RD, Jia, J, Kahonen, M, Launer, LJ, Lehtimaki, T, Liewald, DC, Linneberg, A, Liu, Y, Loos, RJF, Nguyen, VM, Numans, ME, Pedersen, O, Psaty, BM, Raitakari, OT, Rich, SS, Rivadeneira, F, Di Sant, AMR, Rotter, JI, Starr, JM, Taylor, KD, Thuesen, BH, Tracy, RP, Uitterlinden, AG, Wang, J, Dehghan, A, Huo, Y, Cupples, LA, Wilson, JG, Proia, RL, Zon, LI, O'Donnell, CJ, Reiner, AP, Ganesh, SK

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