Evaluation of preparative high performance liquid chromatography and cryoprobe-nuclear magnetic resonance spectroscopy for the early quantitative estimation of drug metabolites in... von Dear, G.J., Roberts, A.D., Beaumont, C., North, S.E.

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TopCount coupled to ultra-performance liquid chromatography for the profiling of radiolabeled drug metabolites in complex biological samples von Dear, G.J., Patel, N., Kelly, P.J., Webber, L., Yung, M.

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Utilisation of water soluble iridium catalysts for signal amplification by reversible exchange von Fekete, M, Gibard, C, Dear, G J, Green, G G R, Hooper, A J J, Roberts, A D, Cisnetti, F, Duckett, S B

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The use of turbulent flow chromatography/mass spectrometry for the rapid, direct analysis of a novel pharmaceutical compound in plasma von Ayrton, J., Dear, G. J., Leavens, W. J., Mallett, D. N., Plumb, R. S.

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The determination of nicotinic acid in plasma by mixed-mode liquid chromatography–tandem mass spectrometry following ion exchange solid phase extraction von Mallett, D.N., Dayal, S., Dear, G.J., Pateman, A.J.

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Optimisation and routine use of generic ultra-high flow-rate liquid chromatography with mass spectrometric detection for the direct on-line analysis of pharmaceuticals in plasma von Ayrton, J, Dear, G.J, Leavens, W.J, Mallett, D.N, Plumb, R.S

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Application of a generic fast gradient liquid chromatography tandem mass spectrometry method for the analysis of cytochrome P450 probe substrates von Ayrton, J., Plumb, R., Leavens, W. J., Mallett, D., Dickins, M., Dear, G. J.

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Ultra-performance liquid chromatography coupled to linear ion trap mass spectrometry for the identification of drug metabolites in biological samples von Dear, G. J., James, A. D., Sarda, S.

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Quantitative analysis of pharmaceuticals in biological fluids using high-performance liquid chromatography coupled to mass spectrometry: a review von Plumb, R. S., Dear, G. J., Mallett, D. N., Higton, D. M., Pleasance, S., Biddlecombe, R. A.

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Characterization of the metabolites of alosetron in experimental animals and human von Ismail, I. M, Andrew, P. D, Cholerton, J, Roberts, A. D, Dear, G. J, Taylor, S, Koch, K. M, Saynor, D. A

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Utilizing a -100 degrees C microplate CCD Imager, yttrium silicate coated 384-microplates and ultra-performance liquid chromatography for improved profiling of radiolabeled drug me... von Dear, G J, Patel, N, Weightman, Alan, Pirard, Hans, Talvitie, Miika

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Utilizing a −100 °C microplate CCD Imager, yttrium silicate coated 384-microplates and ultra-performance liquid chromatography for improved profiling of radiolabeled drug metabolit... von Dear, G.J., Patel, N., Weightman, Alan, Pirard, Hans, Talvitie, Miika

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The rapid identification of drug metabolites using capillary liquid chromatography coupled to an ion trap mass spectrometer von Dear, G. J., Ayrton, J., Plumb, R., Fraser, I. J.

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Urinary metabolites of a novel quinoxaline non-nucleoside reverse transcriptase inhibitor in rabbit, mouse and human: identification of fluorine NIH shift metabolites using NMR and... von Dear, G. J., Ismail, I. M., Mutch, P. J., Plumb, R. S., Davies, L. H., Sweatman, B. C.

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Formation of a defluorinated metabolite of a quinoxaline antiviral drug catalysed by human cytochrome P450 1A2 von Mutch, Peter J., Dear, Gordon J., Ismail, Issy M.

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Ultra-high flow rate capillary liquid chromatography with mass spectrometric detection for the direct analysis of pharmaceuticals in plasma at sub-nanogram per millilitre concentra... von Ayrton, J., Clare, R. A., Dear, G. J., Mallett, D. N., Plumb, R. S.

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N-O glucuronidation: a major human metabolic pathway in the elimination of two novel anticonvulsant drug candidates von Ismail, I. M., Dear, G. J., Roberts, A. D., Plumb, R. S., Ayrton, J., Sweatman, B. C., Bowers, G. D.

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Determination of 4-hydroxytamoxifen in mouse plasma in the pg/mL range by gradient capillary liquid chromatography/tandem mass spectrometry von Plumb, R. S., Warwick, H., Higton, D., Dear, G. J., Mallett, D. N.

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Direct analysis of a polar pharmaceutical compound in plasma using ultra-high flow rate liquid chromatography/mass spectrometry with a mixed-mode column von Mallett, D.N., Dear, G.J., Plumb, R.S.

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The use of preparative high performance liquid chromatography with tandem mass spectrometric directed fraction collection for the isolation and characterisation of drug metabolites... von Plumb, R. S., Ayrton, J., Dear, G. J., Sweatman, B. C., Ismail, I. M.

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