Control of Toll-like Receptor 7 Expression Is Essential to Restrict Autoimmunity and Dendritic Cell Proliferation von Deane, Jonathan A., Pisitkun, Prapaporn, Barrett, Rebecca S., Feigenbaum, Lionel, Town, Terrence, Ward, Jerrold M., Flavell, Richard A., Bolland, Silvia

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Ifih1 gene dose effect reveals MDA5-mediated chronic type I IFN gene signature, viral resistance, and accelerated autoimmunity von Crampton, Steve P, Deane, Jonathan A, Feigenbaum, Lionel, Bolland, Silvia

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Dual signaling by innate and adaptive immune receptors is required for TLR7-induced B-cell–mediated autoimmunity von Walsh, Elizabeth R, Pisitkun, Prapaporn, Voynova, Elisaveta, Deane, Jonathan A, Scott, Bethany L, Caspi, Rachel R, Bolland, Silvia

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Autoreactive B Cell Responses to RNA-Related Antigens Due to TLR7 Gene Duplication von Pisitkun, Prapaporn, Deane, Jonathan A, Difilippantonio, Michael J, Tarasenko, Tatyana, Satterthwaite, Anne B, Bolland, Silvia

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Role of Phosphoinositide 3-Kinase Regulatory Isoforms in Development and Actin Rearrangement von Brachmann, Saskia M., Yballe, Claudine M., Innocenti, Metello, Deane, Jonathan A., Fruman, David A., Thomas, Sheila M., Cantley, Lewis C.

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Sjögren's Syndrome-Like Disease in Mice with T Cells Lacking Class 1A Phosphoinositide-3-Kinase von Oak, Jean S., Deane, Jonathan A., Kharas, Michael G., Luo, Ji, Lane, Thomas E., Cantley, Lewis C., Fruman, David A.

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Class IA Phosphoinositide 3-Kinase Modulates Basal Lymphocyte Motility in the Lymph Node von Matheu, Melanie P, Deane, Jonathan A, Parker, Ian, Fruman, David A, Cahalan, Michael D

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Phosphoinositide 3-kinase: diverse roles in immune cell activation von Deane, Jonathan A, Fruman, David A

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Phosphoinositide 3-kinase signaling is essential for ABL oncogene–mediated transformation of B-lineage cells von Kharas, Michael G., Deane, Jonathan A., Wong, Stephane, O’Bosky, Karen R., Rosenberg, Naomi, Witte, Owen N., Fruman, David A.

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Nucleic Acid-Sensing TLRs as Modifiers of Autoimmunity von Deane, Jonathan A, Bolland, Silvia

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T-cell function is partially maintained in the absence of class IA phosphoinositide 3-kinase signaling von Deane, Jonathan A., Kharas, Michael G., Oak, Jean S., Stiles, Linda N., Luo, Ji, Moore, Travis I., Ji, Hong, Rommel, Christian, Cantley, Lewis C., Lane, Thomas E., Fruman, David A.

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Tangent-Free Property for Periodic Cells Generated by Some General Piecewise Isometries von Yu, Rongzhong, Fu, Xinchu

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Enhanced T Cell Proliferation in Mice Lacking the p85β Subunit of Phosphoinositide 3-Kinase von Deane, Jonathan A., Trifilo, Matthew J., Yballe, Claudine M., Choi, Sangdun, Lane, Thomas E., Fruman, David A.

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Abstract 4128: Identification and characterization of LHC165, a TLR7 agonist designed for localized intratumoral therapies von Deane, Jonathan A., Cortez, German A., Li, Chun, Eifler, Nora, Kasibhatla, Shailaja, Parikh, Nehal, Pan, Shifeng, Bender, Steven

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Dual signaling by innate and adaptive immune receptors is required for TLR7-induced B-celL-mediated autoimmunity von Walsh, Elizabeth R, Pisitkun, Prapaporn, Voynova, Elisaveta, Deane, Jonathan A, Scott, Bethany L, Caspi, Rachel R, Bolland, Silvia

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CD40L is crucial for the development of autoimmunity induced by TLR7 overexpression von Pisitkun, Prapaporn, Deane, Jonathan A., Bolland, Silvia

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Infection with VSV ameliorates autoimmune disease in FcγR2B deficient mice (50.23) von Kole, Hemanta K, Deane, Jonathan A, Bolland, Silvia

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Phenotypes of TLR7 -overexpressing B cells suggest a TLR7 -mediated increase in antigen presentation (129.11) von Pisitkun, Prapaporn, Deane, Jonathan A., Bolland, Silvia

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P hosphoinositide 3-K inase : Diverse Roles in Immune Cell Activation von Deane, Jonathan A., Fruman, David A.

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The p85β regulatory subunit of phosphoinositide 3-kinase has unique and redundant functions in B cells von Oak, Jean S., Chen, Jing, Peralta, Raechel Q., Deane, Jonathan A., Fruman, David A.

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