Genomewide association study for susceptibility genes contributing to familial Parkinson disease von Pankratz, Nathan, Wilk, Jemma B, Latourelle, Jeanne C, DeStefano, Anita L, Halter, Cheryl, Pugh, Elizabeth W, Doheny, Kimberly F, Gusella, James F, Nichols, William C, Foroud, Tatiana, Myers, Richard H

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Bone mineral density and the risk of incident dementia: A meta‐analysis von Lary, Christine W., Ghatan, Samuel, Gerety, Meghan, Hinton, Alexandra, Nagarajan, Archana, Rosen, Clifford, Ross, Ryan D., Bennett, David A., DeStefano, Anita L., Ikram, Mohammad A., Rivadeneira, Fernando, Kiel, Douglas P., Seshadri, Sudha, Beiser, Alexa

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Copy number variation in familial Parkinson disease von Pankratz, Nathan, Dumitriu, Alexandra, Hetrick, Kurt N, Sun, Mei, Latourelle, Jeanne C, Wilk, Jemma B, Halter, Cheryl, Doheny, Kimberly F, Gusella, James F, Nichols, William C, Myers, Richard H, Foroud, Tatiana, DeStefano, Anita L

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Meta-analysis of Parkinson's Disease: Identification of a novel locus, RIT2 von Pankratz, Nathan, Beecham, Gary W., DeStefano, Anita L., Dawson, Ted M., Doheny, Kimberly F., Factor, Stewart A., Hamza, Taye H., Hung, Albert Y., Hyman, Bradley T., Ivinson, Adrian J., Krainc, Dmitri, Latourelle, Jeanne C., Clark, Lorraine N., Marder, Karen, Martin, Eden R., Mayeux, Richard, Ross, Owen A., Scherzer, Clemens R., Simon, David K., Tanner, Caroline, Vance, Jeffery M., Wszolek, Zbigniew K., Zabetian, Cyrus P., Myers, Richard H., Payami, Haydeh, Scott, William K., Foroud, Tatiana

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Large-scale meta-analysis of genome-wide association data identifies six new risk loci for Parkinson's disease von Nalls, Mike A, Pankratz, Nathan, Lill, Christina M, Do, Chuong B, Hernandez, Dena G, Saad, Mohamad, DeStefano, Anita L, Kara, Eleanna, Bras, Jose, Sharma, Manu, Schulte, Claudia, Keller, Margaux F, Arepalli, Sampath, Letson, Christopher, Edsall, Connor, Stefansson, Hreinn, Liu, Xinmin, Pliner, Hannah, Lee, Joseph H, Cheng, Rong, Ikram, M Arfan, Ioannidis, John P A, Hadjigeorgiou, Georgios M, Bis, Joshua C, Martinez, Maria, Perlmutter, Joel S, Goate, Alison, Marder, Karen, Fiske, Brian, Sutherland, Margaret, Xiromerisiou, Georgia, Myers, Richard H, Clark, Lorraine N, Stefansson, Kari, Hardy, John A, Heutink, Peter, Chen, Honglei, Wood, Nicholas W, Houlden, Henry, Payami, Haydeh, Brice, Alexis, Scott, William K, Gasser, Thomas, Bertram, Lars, Eriksson, Nicholas, Foroud, Tatiana, Singleton, Andrew B

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Exome sequencing identifies rare LDLR and APOA5 alleles conferring risk for myocardial infarction von Do, Ron, Stitziel, Nathan O., Won, Hong-Hee, Jørgensen, Anders Berg, Duga, Stefano, Angelica Merlini, Pier, Kiezun, Adam, Farrall, Martin, Goel, Anuj, Zuk, Or, Guella, Illaria, Asselta, Rosanna, Lange, Leslie A., Peloso, Gina M., Auer, Paul L., Girelli, Domenico, Martinelli, Nicola, Farlow, Deborah N., DePristo, Mark A., Roberts, Robert, Stewart, Alexander F. R., Saleheen, Danish, Danesh, John, Epstein, Stephen E., Sivapalaratnam, Suthesh, Kees Hovingh, G., Kastelein, John J., Samani, Nilesh J., Schunkert, Heribert, Erdmann, Jeanette, Shah, Svati H., Kraus, William E., Davies, Robert, Nikpay, Majid, Johansen, Christopher T., Wang, Jian, Hegele, Robert A., Hechter, Eliana, Marz, Winfried, Kleber, Marcus E., Huang, Jie, Johnson, Andrew D., Li, Mingyao, Burke, Greg L., Gross, Myron, Liu, Yongmei, Assimes, Themistocles L., Heiss, Gerardo, Lange, Ethan M., Folsom, Aaron R., Taylor, Herman A., Olivieri, Oliviero, Hamsten, Anders, Clarke, Robert, Reilly, Dermot F., Yin, Wu, Rivas, Manuel A., Donnelly, Peter, Rossouw, Jacques E., Psaty, Bruce M., Herrington, David M., Wilson, James G., Rich, Stephen S., Bamshad, Michael J., Tracy, Russell P., Adrienne Cupples, L., Rader, Daniel J., Reilly, Muredach P., Spertus, John A., Cresci, Sharon, Hartiala, Jaana, Wilson Tang, W. H., Hazen, Stanley L., Allayee, Hooman, Reiner, Alex P., Carlson, Christopher S., Kooperberg, Charles, Jackson, Rebecca D., Boerwinkle, Eric, Lander, Eric S., Schwartz, Stephen M., Siscovick, David S., McPherson, Ruth, Tybjaerg-Hansen, Anne, Abecasis, Goncalo R., Watkins, Hugh, Nickerson, Deborah A., Ardissino, Diego, Sunyaev, Shamil R., O'Donnell, Christopher J., Altshuler, David, Gabriel, Stacey, Kathiresan, Sekar

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Genomewide association study for onset age in Parkinson disease von Latourelle, Jeanne C, Pankratz, Nathan, Dumitriu, Alexandra, Wilk, Jemma B, Goldwurm, Stefano, Pezzoli, Gianni, Mariani, Claudio B, DeStefano, Anita L, Halter, Cheryl, Gusella, James F, Nichols, William C, Myers, Richard H, Foroud, Tatiana

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NeuroX, a fast and efficient genotyping platform for investigation of neurodegenerative diseases von Nalls, Mike A, Bras, Jose, Hernandez, Dena G, Keller, Margaux F, Majounie, Elisa, Renton, Alan E, Saad, Mohamad, Jansen, Iris, Guerreiro, Rita, Lubbe, Steven, Plagnol, Vincent, Gibbs, J. Raphael, Schulte, Claudia, Pankratz, Nathan, Sutherland, Margaret, Bertram, Lars, Lill, Christina M, DeStefano, Anita L, Faroud, Tatiana, Eriksson, Nicholas, Tung, Joyce Y, Edsall, Connor, Nichols, Noah, Brooks, Janet, Arepalli, Sampath, Pliner, Hannah, Letson, Chris, Heutink, Peter, Martinez, Maria, Gasser, Thomas, Traynor, Bryan J, Wood, Nick, Hardy, John, Singleton, Andrew B

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Rare and Coding Region Genetic Variants Associated With Risk of Ischemic Stroke: The NHLBI Exome Sequence Project von Auer, Paul L, Nalls, Mike, Meschia, James F, Worrall, Bradford B, Longstreth, W. T, Seshadri, Sudha, Kooperberg, Charles, Burger, Kathleen M, Carlson, Christopher S, Carty, Cara L, Chen, Wei-Min, Cupples, L. Adrienne, DeStefano, Anita L, Fornage, Myriam, Hardy, John, Hsu, Li, Jackson, Rebecca D, Jarvik, Gail P, Kim, Daniel S, Lakshminarayan, Kamakshi, Lange, Leslie A, Manichaikul, Ani, Quinlan, Aaron R, Singleton, Andrew B, Thornton, Timothy A, Nickerson, Deborah A, Peters, Ulrike, Rich, Stephen S

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Analysis of 6,515 exomes reveals the recent origin of most human protein-coding variants von Fu, Wenqing, O’Connor, Timothy D., Jun, Goo, Kang, Hyun Min, Abecasis, Goncalo, Leal, Suzanne M., Gabriel, Stacey, Rieder, Mark J., Altshuler, David, Shendure, Jay, Nickerson, Deborah A., Bamshad, Michael J., NHLBI Exome Sequencing Project, Akey, Joshua M.

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Quality control and integration of genotypes from two calling pipelines for whole genome sequence data in the Alzheimer's disease sequencing project von Naj, Adam C., Lin, Honghuang, Vardarajan, Badri N., White, Simon, Lancour, Daniel, Ma, Yiyi, Schmidt, Michael, Sun, Fangui, Butkiewicz, Mariusz, Bush, William S., Kunkle, Brian W., Malamon, John, Amin, Najaf, Choi, Seung Hoan, Hamilton-Nelson, Kara L., van der Lee, Sven J., Gupta, Namrata, Koboldt, Daniel C., Saad, Mohamad, Wang, Bowen, Nato, Alejandro Q., Sohi, Harkirat K., Kuzma, Amanda, Wang, Li-San, Cupples, L. Adrienne, van Duijn, Cornelia, Seshadri, Sudha, Schellenberg, Gerard D., Boerwinkle, Eric, Bis, Joshua C., Dupuis, Josée, Salerno, William J., Wijsman, Ellen M., Martin, Eden R., DeStefano, Anita L.

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Recurrent Gain-of-Function Mutation in PRKG1 Causes Thoracic Aortic Aneurysms and Acute Aortic Dissections von Guo, Dong-chuan, Regalado, Ellen, Casteel, Darren E., Santos-Cortez, Regie L., Gong, Limin, Kim, Jeong Joo, Dyack, Sarah, Horne, S. Gabrielle, Chang, Guijuan, Jondeau, Guillaume, Boileau, Catherine, Coselli, Joseph S., Li, Zhenyu, Leal, Suzanne M., Shendure, Jay, Rieder, Mark J., Bamshad, Michael J., Nickerson, Deborah A., Kim, Choel, Milewicz, Dianna M.

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Comprehensive research synopsis and systematic meta-analyses in Parkinson's disease genetics: The PDGene database von Lill, Christina M, Roehr, Johannes T, McQueen, Matthew B, Kavvoura, Fotini K, Bagade, Sachin, Schjeide, Brit-Maren M, Schjeide, Leif M, Meissner, Esther, Zauft, Ute, Allen, Nicole C, Liu, Tian, Schilling, Marcel, Anderson, Kari J, Beecham, Gary, Berg, Daniela, Biernacka, Joanna M, Brice, Alexis, DeStefano, Anita L, Do, Chuong B, Eriksson, Nicholas, Factor, Stewart A, Farrer, Matthew J, Foroud, Tatiana, Gasser, Thomas, Hamza, Taye, Hardy, John A, Heutink, Peter, Hill-Burns, Erin M, Klein, Christine, Latourelle, Jeanne C, Maraganore, Demetrius M, Martin, Eden R, Martinez, Maria, Myers, Richard H, Nalls, Michael A, Pankratz, Nathan, Payami, Haydeh, Satake, Wataru, Scott, William K, Sharma, Manu, Singleton, Andrew B, Stefansson, Kari, Toda, Tatsushi, Tung, Joyce Y, Vance, Jeffery, Wood, Nick W, Zabetian, Cyrus P, Young, Peter, Tanzi, Rudolph E, Khoury, Muin J, Zipp, Frauke, Lehrach, Hans, Ioannidis, John P A, Bertram, Lars

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Large‐scale sequencing studies expand the known genetic architecture of Alzheimer's disease von Xue, Diane, Bush, William S., Renton, Alan E., Marcora, Edoardo A., Bis, Joshua C., Kunkle, Brian W., Boerwinkle, Eric, DeStefano, Anita L., Farrer, Lindsay, Goate, Alison, Mayeux, Richard, Pericak‐Vance, Margaret, Schellenberg, Gerard, Seshadri, Sudha, Wijsman, Ellen, Haines, Jonathan L., Blue, Elizabeth E.

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Common variants at 12q14 and 12q24 are associated with hippocampal volume von Bis, Joshua C, DeCarli, Charles, Smith, Albert Vernon, van der Lijn, Fedde, Crivello, Fabrice, Fornage, Myriam, Debette, Stephanie, Shulman, Joshua M, Schmidt, Helena, Srikanth, Velandai, Schuur, Maaike, Yu, Lei, Choi, Seung-Hoan, Sigurdsson, Sigurdur, Verhaaren, Benjamin F J, DeStefano, Anita L, Lambert, Jean-Charles, Jack, Jr, Clifford R, Struchalin, Maksim, Stankovich, Jim, Ibrahim-Verbaas, Carla A, Fleischman, Debra, Zijdenbos, Alex, den Heijer, Tom, Mazoyer, Bernard, Coker, Laura H, Enzinger, Christian, Danoy, Patrick, Amin, Najaf, Arfanakis, Konstantinos, van Buchem, Mark A, de Bruijn, Renée F A G, Beiser, Alexa, Dufouil, Carole, Huang, Juebin, Cavalieri, Margherita, Thomson, Russell, Niessen, Wiro J, Chibnik, Lori B, Gislason, Gauti K, Hofman, Albert, Pikula, Aleksandra, Amouyel, Philippe, Freeman, Kevin B, Phan, Thanh G, Oostra, Ben A, Stein, Jason L, Medland, Sarah E, Vasquez, Alejandro Arias, Hibar, Derrek P, Wright, Margaret J, Franke, Barbara, Martin, Nicholas G, Thompson, Paul M, Nalls, Michael A, Uitterlinden, Andre G, Au, Rhoda, Elbaz, Alexis, Beare, Richard J, van Swieten, John C, Lopez, Oscar L, Harris, Tamara B, Chouraki, Vincent, Breteler, Monique M B, De Jager, Philip L, Becker, James T, Vernooij, Meike W, Knopman, David, Fazekas, Franz, Wolf, Philip A, van der Lugt, Aad, Gudnason, Vilmundur, Longstreth, Jr, W T, Brown, Matthew A, Bennett, David A, van Duijn, Cornelia M, Mosley, Thomas H, Schmidt, Reinhold, Tzourio, Christophe, Launer, Lenore J, Ikram, M Arfan, Seshadri, Sudha

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Genome-wide association studies of cerebral white matter lesion burden von Fornage, Myriam, Debette, Stephanie, Bis, Joshua C., Schmidt, Helena, Ikram, M. Arfan, Dufouil, Carole, Sigurdsson, Sigurdur, Lumley, Thomas, DeStefano, Anita L., Fazekas, Franz, Vrooman, Henri A., Shibata, Dean K., Maillard, Pauline, Zijdenbos, Alex, Smith, Albert V., Gudnason, Haukur, de Boer, Renske, Cushman, Mary, Mazoyer, Bernard, Heiss, Gerardo, Vernooij, Meike W., Enzinger, Christian, Glazer, Nicole L., Beiser, Alexa, Knopman, David S., Cavalieri, Margherita, Niessen, Wiro J., Harris, Tamara B., Petrovic, Katja, Lopez, Oscar L., Au, Rhoda, Lambert, Jean-Charles, Hofman, Albert, Gottesman, Rebecca F., Garcia, Melissa, Heckbert, Susan R., Atwood, Larry D., Catellier, Diane J., Uitterlinden, Andre G., Yang, Qiong, Smith, Nicholas L., Aspelund, Thor, Romero, Jose R., Rice, Kenneth, Taylor, Kent D., Nalls, Michael A., Rotter, Jerome I., Sharrett, Richey, van Duijn, Cornelia M., Amouyel, Philippe, Wolf, Philip A., Gudnason, Vilmundur, van der Lugt, Aad, Boerwinkle, Eric, Psaty, Bruce M., Seshadri, Sudha, Tzourio, Christophe, Breteler, Monique M. B., Mosley, Thomas H., Schmidt, Reinhold, Longstreth, W. T., DeCarli, Charles, Launer, Lenore J.

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Pathogenic Variants for Mendelian and Complex Traits in Exomes of 6,517 European and African Americans: Implications for the Return of Incidental Results von Tabor, Holly K., Auer, Paul L., Jamal, Seema M., Chong, Jessica X., Yu, Joon-Ho, Gordon, Adam S., Graubert, Timothy A., O’Donnell, Christopher J., Rich, Stephen S., Nickerson, Deborah A., Bamshad, Michael J.

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Whole genome sequence association analysis of Brain MRI measures von Shade, Lincoln MP, Satizabal, Claudia L, Glahn, David C, Mosley, Thomas H, Heckbert, Susan R., Launer, Lenore J., Yanek, Lisa R, Bis, Joshua C, Smith, Jennifer A, DeCarli, Charles S., Arnett, Donna K, Psaty, Bruce M., Nyquist, Paul A, Mathias, Rasika A, Rotter, Jerome I, Rich, Stephen S, Blangero, John, DeStefano, Anita L., Fardo, David W., Fornage, Myriam, Seshadri, Sudha, Sarnowski, Chloé

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Rare Functional Variant in TM2D3 is Associated with Late-Onset Alzheimer's Disease von Jakobsdottir, Johanna, van der Lee, Sven J, Bis, Joshua C, Chouraki, Vincent, Li-Kroeger, David, Yamamoto, Shinya, Grove, Megan L, Naj, Adam, Vronskaya, Maria, Salazar, Jose L, DeStefano, Anita L, Brody, Jennifer A, Smith, Albert V, Amin, Najaf, Sims, Rebecca, Ibrahim-Verbaas, Carla A, Choi, Seung-Hoan, Satizabal, Claudia L, Lopez, Oscar L, Beiser, Alexa, Ikram, M Arfan, Garcia, Melissa E, Hayward, Caroline, Varga, Tibor V, Ripatti, Samuli, Franks, Paul W, Hallmans, Göran, Rolandsson, Olov, Jansson, Jan-Håkon, Porteous, David J, Salomaa, Veikko, Eiriksdottir, Gudny, Rice, Kenneth M, Bellen, Hugo J, Levy, Daniel, Uitterlinden, Andre G, Emilsson, Valur, Rotter, Jerome I, Aspelund, Thor, O'Donnell, Christopher J, Fitzpatrick, Annette L, Launer, Lenore J, Hofman, Albert, Wang, Li-San, Williams, Julie, Schellenberg, Gerard D, Boerwinkle, Eric, Psaty, Bruce M, Seshadri, Sudha, Shulman, Joshua M, Gudnason, Vilmundur, van Duijn, Cornelia M

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Predicting Stroke Through Genetic Risk Functions The CHARGE Risk Score Project von IBRAHIM-VERBAAS, Carla A, FORNAGE, Myriam, KATHIRESAN, Sekar, EHRET, Georg B, FOX, Caroline S, MALIK, Rainer, DICHGANS, Martin, SCHMIDT, Helena, LAHTI, Jari, HECKBERT, Susan R, LUMLEY, Thomas, RICE, Kenneth, BIS, Joshua C, ROTTER, Jerome I, TAYLOR, Kent D, FOLSOM, Aaron R, BOERWINKLE, Eric, ROSAMOND, Wayne D, SHAHAR, Eyal, GOTTESMAN, Rebecca F, KOUDSTAAL, Peter J, AMIN, Najaf, WIEBERDINK, Renske G, SEUNG HOAN CHOI, DEHGHAN, Abbas, HOFMAN, Albert, UITTERLINDEN, André G, DESTEFANO, Anita L, DEBETTE, Stephanie, LUTING XUE, BEISER, Alexa, WOLF, Philip A, DECARLI, Charles, IKRAM, M. Arfan, PSATY, Bruce M, SESHADRI, Sudha, MOSLEY, Thomas H, LONGSTRETH, W. T, VAN DUIJN, Cornelia M, LAUNER, Lenore J, MEIGS, James B, RAO, Madhu, NALLS, Mike, FONTES, Joao D, O'DONNELL, Christopher J

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