Progesterone Interacts with P-Glycoprotein in Multidrug-resistant Cells and in the Endometrium of Gravid Uterus von Yang, C P H, DePinho, S G, Greenberger, L M, Arceci, R J, Horwitz, S B

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FoxO1 integrates direct and indirect effects of insulin on hepatic glucose production and glucose utilization von O-Sullivan, InSug, Zhang, Wenwei, Wasserman, David H., Liew, Chong Wee, Liu, Jonathan, Paik, Jihye, DePinho, Ronald A., Stolz, Donna Beer, Kahn, C. Ronald, Schwartz, Michael W., Unterman, Terry G.

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Context-Dependent Transformation of Adult Pancreatic Cells by Oncogenic K-Ras von Friedlander, Sharon Y. Gidekel, Chu, Gerald C., Snyder, Eric L., Girnius, Nomeda, Dibelius, Gregory, Crowley, Denise, Vasile, Eliza, DePinho, Ronald A., Jacks, Tyler

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Telomere dysfunction promotes non-reciprocal translocations and epithelial cancers in mice von DePinho, Ronald A, Artandi, Steven E, Chang, Sandy, Lee, Shwu-Luan, Alson, Scott, Gottlieb, Geoffrey J, Chin, Lynda

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The WNT receptor ROR2 drives the interaction of multiple myeloma cells with the microenvironment through AKT activation von Frenquelli, M., Caridi, N., Antonini, E., Storti, F., Viganò, V., Gaviraghi, M., Occhionorelli, M., Bianchessi, S., Bongiovanni, L., Spinelli, A., Marcatti, M., Belloni, D., Ferrero, E., Karki, S., Brambilla, P., Martinelli-Boneschi, F., Colla, S., Ponzoni, M., DePinho, R. A., Tonon, G.

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Fungal mycobiome drives IL-33 secretion and type 2 immunity in pancreatic cancer von Alam, Aftab, Levanduski, Eric, Denz, Parker, Villavicencio, Helena Solleiro, Bhatta, Maulasri, Alhorebi, Lamees, Zhang, Yali, Gomez, Eduardo Cortes, Morreale, Brian, Senchanthisai, Sharon, Li, Jun, Turowski, Steven G., Sexton, Sandra, Sait, Sheila Jani, Singh, Prashant K., Wang, Jianmin, Maitra, Anirban, Kalinski, Pawel, DePinho, Ronald A., Wang, Huamin, Liao, Wenting, Abrams, Scott I., Segal, Brahm H., Dey, Prasenjit

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FoxOs Are Critical Mediators of Hematopoietic Stem Cell Resistance to Physiologic Oxidative Stress von Tothova, Zuzana, Kollipara, Ramya, Huntly, Brian J., Lee, Benjamin H., Castrillon, Diego H., Cullen, Dana E., McDowell, Elizabeth P., Lazo-Kallanian, Suzan, Williams, Ifor R., Sears, Christopher, Armstrong, Scott A., Passegué, Emmanuelle, DePinho, Ronald A., Gilliland, D. Gary

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PKM2 Isoform-Specific Deletion Reveals a Differential Requirement for Pyruvate Kinase in Tumor Cells von Israelsen, William J., Dayton, Talya L., Davidson, Shawn M., Fiske, Brian P., Hosios, Aaron M., Bellinger, Gary, Li, Jie, Yu, Yimin, Sasaki, Mika, Horner, James W., Burga, Laura N., Xie, Jianxin, Jurczak, Michael J., DePinho, Ronald A., Clish, Clary B., Jacks, Tyler, Kibbey, Richard G., Wulf, Gerburg M., Di Vizio, Dolores, Mills, Gordon B., Cantley, Lewis C., Vander Heiden, Matthew G.

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Forkhead box O transcription factors in chondrocytes regulate endochondral bone formation von Eelen, G., Verlinden, L., Maes, C., Beullens, I., Gysemans, C., Paik, J.-H., DePinho, R.A., Bouillon, R., Carmeliet, G., Verstuyf, A.

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A Genetic Screen for Candidate Tumor Suppressors Identifies REST von Westbrook, Thomas F., Martin, Eric S., Schlabach, Michael R., Leng, Yumei, Liang, Anthony C., Feng, Bin, Zhao, Jean J., Roberts, Thomas M., Mandel, Gail, Hannon, Gregory J., DePinho, Ronald A., Chin, Lynda, Elledge, Stephen J.

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Tumor heterogeneity is an active process maintained by a mutant EGFR-induced cytokine circuit in glioblastoma von Inda, Maria-del-Mar, Bonavia, Rudy, Mukasa, Akitake, Narita, Yoshitaka, Sah, Dinah W Y, Vandenberg, Scott, Brennan, Cameron, Johns, Terrance G, Bachoo, Robert, Hadwiger, Philipp, Tan, Pamela, Depinho, Ronald A, Cavenee, Webster, Furnari, Frank

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Tumor Evolution of Glioma-Intrinsic Gene Expression Subtypes Associates with Immunological Changes in the Microenvironment von Wang, Qianghu, Hu, Baoli, Hu, Xin, Kim, Hoon, Squatrito, Massimo, Scarpace, Lisa, deCarvalho, Ana C., Lyu, Sali, Li, Pengping, Li, Yan, Barthel, Floris, Cho, Hee Jin, Lin, Yu-Hsi, Satani, Nikunj, Martinez-Ledesma, Emmanuel, Zheng, Siyuan, Chang, Edward, Sauvé, Charles-Etienne Gabriel, Olar, Adriana, Lan, Zheng D., Finocchiaro, Gaetano, Phillips, Joanna J., Berger, Mitchel S., Gabrusiewicz, Konrad R., Wang, Guocan, Eskilsson, Eskil, Hu, Jian, Mikkelsen, Tom, DePinho, Ronald A., Muller, Florian, Heimberger, Amy B., Sulman, Erik P., Nam, Do-Hyun, Verhaak, Roel G.W.

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Essential role for oncogenic Ras in tumour maintenance von Chin, Lynda, DePinho#, Ronald A, Tam, Alice, Pomerantz, Jason, Wong, Michelle, Holash, Jocelyn, Bardeesy, Nabeel, Shen, Qiong, O'Hagan, Ronan, Pantginis, Joe, Zhou, Hao, Horner, James W, Cordon-Cardo, Carlos, Yancopoulos, George D

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Synthetic vulnerabilities of mesenchymal subpopulations in pancreatic cancer von Genovese, Giannicola, Carugo, Alessandro, Tepper, James, Robinson, Frederick Scott, Li, Liren, Svelto, Maria, Nezi, Luigi, Corti, Denise, Minelli, Rosalba, Pettazzoni, Piergiorgio, Gutschner, Tony, Wu, Chia-Chin, Seth, Sahil, Akdemir, Kadir Caner, Leo, Elisabetta, Amin, Samirkumar, Molin, Marco Dal, Ying, Haoqiang, Kwong, Lawrence N., Colla, Simona, Takahashi, Koichi, Ghosh, Papia, Giuliani, Virginia, Muller, Florian, Dey, Prasenjit, Jiang, Shan, Garvey, Jill, Liu, Chang-Gong, Zhang, Jianhua, Heffernan, Timothy P., Toniatti, Carlo, Fleming, Jason B., Goggins, Michael G., Wood, Laura D., Sgambato, Alessandro, Agaimy, Abbas, Maitra, Anirban, Roberts, Charles W. M., Wang, Huamin, Viale, Andrea, DePinho, Ronald A., Draetta, Giulio F., Chin, Lynda

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Essential role of limiting telomeres in the pathogenesis of Werner syndrome von Chang, Sandy, DePinho, Ronald A, Multani, Asha S, Cabrera, Noelia G, Naylor, Maria L, Laud, Purnima, Lombard, David, Pathak, Sen, Guarente, Leonard

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Mouse Model for Noninvasive Imaging of HIF Prolyl Hydroxylase Activity: Assessment of an Oral Agent That Stimulates Erythropoietin Production von Safran, Michal, Kim, William Y., O'Connell, Fionnuala, Flippin, Lee, Günzler, Volkmar, Horner, James W., DePinho, Ronald A., Kaelin, William G.

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FoxOs Are Lineage-Restricted Redundant Tumor Suppressors and Regulate Endothelial Cell Homeostasis von Paik, Ji-Hye, Kollipara, Ramya, Chu, Gerald, Ji, Hongkai, Xiao, Yonghong, Ding, Zhihu, Miao, Lili, Tothova, Zuzana, Horner, James W., Carrasco, Daniel R., Jiang, Shan, Gilliland, D. Gary, Chin, Lynda, Wong, Wing H., Castrillon, Diego H., DePinho, Ronald A.

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IL-7 Engages Multiple Mechanisms to Overcome Chronic Viral Infection and Limit Organ Pathology von Pellegrini, Marc, Calzascia, Thomas, Toe, Jesse G., Preston, Simon P., Lin, Amy E., Elford, Alisha R., Shahinian, Arda, Lang, Philipp A., Lang, Karl S., Morre, Michel, Assouline, Brigitte, Lahl, Katharina, Sparwasser, Tim, Tedder, Thomas F., Paik, Ji-hye, DePinho, Ronald A., Basta, Sameh, Ohashi, Pamela S., Mak, Tak W.

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High-resolution genomic profiles define distinct clinico-pathogenetic subgroups of multiple myeloma patients von Carrasco, Daniel R., Tonon, Giovanni, Huang, Yongsheng, Zhang, Yunyu, Sinha, Raktim, Feng, Bin, Stewart, James P., Zhan, Fenghuang, Khatry, Deepak, Protopopova, Marina, Protopopov, Alexei, Sukhdeo, Kumar, Hanamura, Ichiro, Stephens, Owen, Barlogie, Bart, Anderson, Kenneth C., Chin, Lynda, Shaughnessy, John D., Brennan, Cameron, DePinho, Ronald A.

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3D imaging analysis on an organoid-based platform guides personalized treatment in pancreatic ductal adenocarcinoma von Kang, Ya'an, Deng, Jenying, Ling, Jianhua, Li, Xinqun, Chiang, Yi-Ju, Koay, Eugene J, Wang, Huamin, Burks, Jared K, Chiao, Paul J, Hurd, Mark W, Bhutani, Manoop S, Lee, Jeffrey H, Weston, Brian R, Maitra, Anirban, Ikoma, Naruhiko, Tzeng, Ching-Wei D, Lee, Jeffrey E, DePinho, Ronald A, Wolff, Robert A, Pant, Shubham, McAllister, Florencia, Katz, Matthew Hg, Fleming, Jason B, Kim, Michael P

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