Telomeres: history, health, and hallmarks of aging von Chakravarti, Deepavali, LaBella, Kyle A., DePinho, Ronald A.

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Genetics and biology of prostate cancer von Wang, Guocan, Zhao, Di, Spring, Denise J, DePinho, Ronald A

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Metabolic Codependencies in the Tumor Microenvironment von Dey, Prasenjit, Kimmelman, Alec C., DePinho, Ronald A.

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Genetics and biology of pancreatic ductal adenocarcinoma von Ying, Haoqiang, Dey, Prasenjit, Yao, Wantong, Kimmelman, Alec C, Draetta, Giulio F, Maitra, Anirban, DePinho, Ronald A

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Symbiotic Macrophage-Glioma Cell Interactions Reveal Synthetic Lethality in PTEN-Null Glioma von Chen, Peiwen, Zhao, Di, Li, Jun, Liang, Xin, Li, Jiexi, Chang, Andrew, Henry, Verlene K., Lan, Zhengdao, Spring, Denise J., Rao, Ganesh, Wang, Y. Alan, DePinho, Ronald A.

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Regulation of autophagy and the ubiquitin–proteasome system by the FoxO transcriptional network during muscle atrophy von Milan, Giulia, Romanello, Vanina, Pescatore, Francesca, Armani, Andrea, Paik, Ji-Hye, Frasson, Laura, Seydel, Anke, Zhao, Jinghui, Abraham, Reimar, Goldberg, Alfred L., Blaauw, Bert, DePinho, Ronald A., Sandri, Marco

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Yap1 Activation Enables Bypass of Oncogenic Kras Addiction in Pancreatic Cancer von Kapoor, Avnish, Yao, Wantong, Ying, Haoqiang, Hua, Sujun, Liewen, Alison, Wang, Qiuyun, Zhong, Yi, Wu, Chang-Jiun, Sadanandam, Anguraj, Hu, Baoli, Chang, Qing, Chu, Gerald C., Al-Khalil, Ramsey, Jiang, Shan, Xia, Hongai, Fletcher-Sananikone, Eliot, Lim, Carol, Horwitz, Gillian I., Viale, Andrea, Pettazzoni, Piergiorgio, Sanchez, Nora, Wang, Huamin, Protopopov, Alexei, Zhang, Jianhua, Heffernan, Timothy, Johnson, Randy L., Chin, Lynda, Wang, Y. Alan, Draetta, Giulio, DePinho, Ronald A.

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Effective combinatorial immunotherapy for castration-resistant prostate cancer von Lu, Xin, Horner, James W., Paul, Erin, Shang, Xiaoying, Troncoso, Patricia, Deng, Pingna, Jiang, Shan, Chang, Qing, Spring, Denise J., Sharma, Padmanee, Zebala, John A., Maeda, Dean Y., Wang, Y. Alan, DePinho, Ronald A.

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Deacetylation of FoxO by Sirt1 Plays an Essential Role in Mediating Starvation-Induced Autophagy in Cardiac Myocytes von Hariharan, Nirmala, Maejima, Yasuhiro, Nakae, Jun, Paik, Jihye, DePinho, Ronald A, Sadoshima, Junichi

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An inhibitor of oxidative phosphorylation exploits cancer vulnerability von Molina, Jennifer R., Sun, Yuting, Protopopova, Marina, Gera, Sonal, Bandi, Madhavi, Bristow, Christopher, McAfoos, Timothy, Morlacchi, Pietro, Ackroyd, Jeffrey, Agip, Ahmed-Noor A., Al-Atrash, Gheath, Asara, John, Bardenhagen, Jennifer, Carrillo, Caroline C., Carroll, Christopher, Chang, Edward, Ciurea, Stefan, Cross, Jason B., Czako, Barbara, Deem, Angela, Daver, Naval, de Groot, John Frederick, Dong, Jian-Wen, Feng, Ningping, Gao, Guang, Gay, Jason, Do, Mary Geck, Greer, Jennifer, Giuliani, Virginia, Han, Jing, Han, Lina, Henry, Verlene K., Hirst, Judy, Huang, Sha, Jiang, Yongying, Kang, Zhijun, Khor, Tin, Konoplev, Sergej, Lin, Yu-Hsi, Liu, Gang, Lodi, Alessia, Lofton, Timothy, Ma, Helen, Mahendra, Mikhila, Matre, Polina, Mullinax, Robert, Peoples, Michael, Petrocchi, Alessia, Rodriguez-Canale, Jaime, Serreli, Riccardo, Shi, Thomas, Smith, Melinda, Tabe, Yoko, Theroff, Jay, Tiziani, Stefano, Xu, Quanyun, Zhang, Qi, Muller, Florian, DePinho, Ronald A., Toniatti, Carlo, Draetta, Giulio F., Heffernan, Timothy P., Konopleva, Marina, Jones, Philip, Di Francesco, M. Emilia, Marszalek, Joseph R.

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The Autophagy-related Gene 14 (Atg14) Is Regulated by Forkhead Box O Transcription Factors and Circadian Rhythms and Plays a Critical Role in Hepatic Autophagy and Lipid Metabolism von Xiong, Xiwen, Tao, Rongya, DePinho, Ronald A., Dong, X.Charlie

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The mighty mouse: genetically engineered mouse models in cancer drug development von Sharpless, Norman E, DePinho, Ronald A

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Deletion of hepatic FoxO1/3/4 genes in mice significantly impacts on glucose metabolism through downregulation of gluconeogenesis and upregulation of glycolysis von Xiong, Xiwen, Tao, Rongya, DePinho, Ronald A, Dong, X Charlie

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Impaired Regulation of Hepatic Glucose Production in Mice Lacking the Forkhead Transcription Factor Foxo1 in Liver von Matsumoto, Michihiro, Pocai, Alessandro, Rossetti, Luciano, DePinho, Ronald A., Accili, Domenico

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FoxO Transcription Factors Promote Cardiomyocyte Survival upon Induction of Oxidative Stress von Sengupta, Arunima, Molkentin, Jeffery D., Paik, Ji-Hye, DePinho, Ronald A., Yutzey, Katherine E.

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FoxO3 Transcription Factor and Sirt6 Deacetylase Regulate Low Density Lipoprotein (LDL)-cholesterol Homeostasis via Control of the Proprotein Convertase Subtilisin/Kexin Type 9 (Pc... von Tao, Rongya, Xiong, Xiwen, DePinho, Ronald A., Deng, Chu-Xia, Dong, X. Charlie

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Generation of functional insulin-producing cells in the gut by Foxo1 ablation von Talchai, Chutima, Xuan, Shouhong, Kitamura, Tadahiro, DePinho, Ronald A, Accili, Domenico

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FoxO1 integrates direct and indirect effects of insulin on hepatic glucose production and glucose utilization von O-Sullivan, InSug, Zhang, Wenwei, Wasserman, David H., Liew, Chong Wee, Liu, Jonathan, Paik, Jihye, DePinho, Ronald A., Stolz, Donna Beer, Kahn, C. Ronald, Schwartz, Michael W., Unterman, Terry G.

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Histone demethylase KDM5D upregulation drives sex differences in colon cancer von Li, Jiexi, Lan, Zhengdao, Liao, Wenting, Horner, James W., Xu, Xueping, Liu, Jielin, Yoshihama, Yohei, Jiang, Shan, Shim, Hong Seok, Slotnik, Max, LaBella, Kyle A., Wu, Chang-Jiun, Dunner, Kenneth, Hsu, Wen-Hao, Lee, Rumi, Khanduri, Isha, Terranova, Christopher, Akdemir, Kadir, Chakravarti, Deepavali, Shang, Xiaoying, Spring, Denise J., Wang, Y. Alan, DePinho, Ronald A.

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Genomic deletion of malic enzyme 2 confers collateral lethality in pancreatic cancer von Dey, Prasenjit, Baddour, Joelle, Muller, Florian, Wu, Chia Chin, Wang, Huamin, Liao, Wen-Ting, Lan, Zangdao, Chen, Alina, Gutschner, Tony, Kang, Yaan, Fleming, Jason, Satani, Nikunj, Zhao, Di, Achreja, Abhinav, Yang, Lifeng, Lee, Jiyoon, Chang, Edward, Genovese, Giannicola, Viale, Andrea, Ying, Haoqiang, Draetta, Giulio, Maitra, Anirban, Wang, Y. Alan, Nagrath, Deepak, DePinho, Ronald A.

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